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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Inogatran

    CAS:
    <p>Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.</p>
    Formula:C21H38N6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.56
  • Paltimatrectinib

    CAS:
    <p>Paltimatrectinib (PBI-200) is a tyrosine kinase inhibitor with anticancer activity, and is used in the study of bladder, breast, and colorectal cancers.</p>
    Formula:C20H15F5N6
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:434.37
  • ABP 25

    CAS:
    <p>ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.</p>
    Formula:C55H66ClN5O3
    Color and Shape:Solid
    Molecular weight:880.6
  • Beclabuvir HCl

    CAS:
    <p>Beclabuvir (BMS-791325) is an HCV inhibitor targeting NS5B polymerase with sub-28 nM potency for genotypes 1, 3, 4, 5.</p>
    Formula:C36H46ClN5O5S
    Color and Shape:Solid
    Molecular weight:696.3
  • BAY-678

    CAS:
    <p>BAY-678: Oral selective human neutrophil elastase inhibitor; IC50: 20 nM; SGC-approved chemical probe.</p>
    Formula:C20H15F3N4O2
    Purity:97.89%
    Color and Shape:Solid
    Molecular weight:400.35
  • Proteasome-IN-5

    CAS:
    <p>Proteasome-IN-5, also known as compound 5, acts as a proteasome inhibitor [1].</p>
    Formula:C20H30BN5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:463.29
  • Collagen proline hydroxylase inhibitor

    CAS:
    <p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>
    Formula:C18H18N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:354.36
  • Ro 31-9790

    CAS:
    <p>Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).</p>
    Formula:C15H29N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:315.41
  • ONO 4817

    CAS:
    <p>ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.</p>
    Formula:C22H28N2O6
    Color and Shape:Solid
    Molecular weight:416.47
  • MMP-7-IN-3

    CAS:
    <p>MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.</p>
    Formula:C34H43ClF3N7O9S
    Purity:99.915%
    Color and Shape:Solid
    Molecular weight:818.26
  • KB-R7785

    CAS:
    <p>KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.</p>
    Formula:C18H27N3O4
    Color and Shape:Solid
    Molecular weight:349.42
  • Cipemastat

    CAS:
    <p>Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).</p>
    Formula:C22H36N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:436.55
  • Azt-pmap

    CAS:
    <p>AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].</p>
    Formula:C20H25N6O8P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:508.42
  • XL-784 free base

    CAS:
    <p>XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).</p>
    Formula:C21H22ClF2N3O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:549.93
  • MDL 27324

    CAS:
    <p>MDL 27324 is an inhibitor of human neutrophil elastase.</p>
    Formula:C29H38F3N5O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:641.7
  • AA74-1

    CAS:
    <p>AA74-1 is a potent, selective APEH inhibitor that significantly enhances T-cell proliferation by inhibiting APEH activity [1].</p>
    Formula:C16H28N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:308.42
  • Ro 32-7315

    CAS:
    <p>Ro 32-7315 is a selective inhibitor of ADAM17.</p>
    Formula:C22H35N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:453.6
  • MK-3281

    CAS:
    <p>MK-3281: Oral, potent HCV NS5B inhibitor with promising properties and efficacy in replication trials, suitable for clinical use.</p>
    Formula:C29H37N3O3
    Color and Shape:Solid
    Molecular weight:475.62
  • MDL 101146

    CAS:
    <p>MDL 101146 is an orally active neutrophil elastase inhibitor.</p>
    Formula:C29H37F5N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:632.62
  • JW 480

    CAS:
    <p>JW480 is a potent and selective inhibitor of KIAA1363, a serine hydrolase enzyme.</p>
    Formula:C22H23NO2
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:333.42