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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 985 products of "Proteases/Proteasome"

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  • Anti-infective agent 10

    CAS:
    Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.
    Formula:C26H25N3O7S
    Color and Shape:Solid
    Molecular weight:523.56

    Ref: TM-T207374

    10mg
    To inquire
    50mg
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  • Freselestat quarterhydrate


    ONO-6818 quarterhydrate: oral neutrophil elastase inhibitor, Ki 12.2 nM; >100x less effective on other proteases; strong anti-inflammatory.
    Formula:C23H30N6O5
    Color and Shape:Solid
    Molecular weight:457.03

    Ref: TM-T62846

    25mg
    1,026.00€
    50mg
    1,341.00€
    100mg
    2,052.00€
  • SD-2590 HCl

    CAS:
    SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.
    Formula:C22H26ClF3N2O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:554.96

    Ref: TM-T24775

    1mg
    148.00€
    5mg
    447.00€
  • CE-2072

    CAS:
    CE-2072 is a synthetic host serine proteases inhibitor.
    Formula:C33H41N5O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:603.71

    Ref: TM-T25218

    25mg
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    50mg
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    100mg
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  • Faldaprevir sodium

    CAS:
    Faldaprevir sodium: HCV treatment, inhibits NS3/NS4A protease, P-glycoprotein, CYP3A4, UGT1A1.
    Formula:C40H48BrN6NaO9S
    Color and Shape:Solid
    Molecular weight:891.81

    Ref: TM-T71215

    25mg
    2,718.00€
    50mg
    3,582.00€
    100mg
    4,950.00€
  • Immunoproteasome activator 1

    CAS:
    Immunoproteasome Activator 1 (compound A) is a selective immunoproteasome activator that enhances the presentation of individual MHC-I binding peptides by over 100 times. It binds to the proteasomal structural subunit PSMA1 and facilitates the association of the proteasome activators PA28α/β (PSME1/PSME2) with the immunoproteasome.
    Formula:C24H23N3O3
    Color and Shape:Solid
    Molecular weight:401.46

    Ref: TM-T200985

    25mg
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    50mg
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    100mg
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  • AEP-IN-1


    APE-IN-1, a potent AEP inhibitor (IC50: 89 nM), aids Alzheimer's diagnosis and drug research.
    Formula:C18H27N3O3
    Color and Shape:Solid
    Molecular weight:333.43

    Ref: TM-T61004

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Pyridoxatin

    CAS:
    Pyridoxatin: fungal metabolite; blocks TBARS production, prevents AAPH-induced hemolysis, and acts against C. albicans.
    Formula:C15H21NO3
    Color and Shape:Solid
    Molecular weight:263.33

    Ref: TM-T70891

    1mg
    298.00€
    500µg
    178.00€
  • JBIR-22

    CAS:
    JBIR-22 is a natural inhibitor for protein−protein interaction of the homodimer of proteasome assembly factor 3.
    Formula:C23H33NO6
    Color and Shape:Solid
    Molecular weight:419.51

    Ref: TM-T71203

    25mg
    2,448.00€
    50mg
    3,222.00€
    100mg
    4,410.00€
  • Enantiomer of Sofosbuvir


    Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.
    Formula:C22H29FN3O9P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:529.45

    Ref: TM-T11195

    25mg
    1,494.00€
    50mg
    2,043.00€
    100mg
    2,512.00€
  • RDN2150

    CAS:
    RDN2150 (Compound 25), a ZAP-70 inhibitor with an IC50 of 14.6 nM, covalently binds to the C346 residue of ZAP-70, suppressing the expression of CD25 and CD69
    Formula:C28H29ClN8O4
    Color and Shape:Solid
    Molecular weight:577.03

    Ref: TM-T81308

    1mg
    260.00€
    5mg
    580.00€
    10mg
    888.00€
    25mg
    1,783.00€
    50mg
    2,943.00€
    100mg
    3,979.00€
  • JBJ-08-178-01

    CAS:
    JBJ-08-178-01, a mutant-selective tyrosine kinase inhibitor, targets (HER2) human epidermal growth factor receptor 2 and exhibits antitumoral activity. This compound not only diminishes HER2's kinase activity and protein levels through the induction of proteasomal degradation of the receptor but also shows promise in non-small-cell lung cancer research.
    Formula:C31H30N8O3
    Color and Shape:Solid
    Molecular weight:562.62

    Ref: TM-T200308

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • RIPK1-IN-26

    CAS:
    RIPK1-IN-26 is a potent inhibitor of Receptor-Interacting Serine/Threonine Kinase 1 (RIPK1), exhibiting anti-necrotic properties in cells. This compound demonstrates good metabolic stability and binding specificity in mice. RIPK1-IN-26 holds potential for development as a PET imaging probe and in the research of neurodegenerative diseases.
    Formula:C15H20FNO2
    Color and Shape:Solid
    Molecular weight:265.32

    Ref: TM-T200690

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • PLGLAG

    CAS:
    PLGLAG is a peptide chain that acts as a linker in activatable cell-penetrating peptides (ACPPs). ACPPs containing the PLGLAG linker are primarily sensitive to MMP-2 and MMP-9 in vivo. PLGLAG is applicable in cancer research.
    Formula:C24H42N6O7
    Color and Shape:Solid
    Molecular weight:526.63

    Ref: TM-TP3961

    10mg
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    50mg
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  • Cyclophilin inhibitor 1

    CAS:
    Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.
    Formula:C31H39N5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:593.67

    Ref: TM-T10919

    25mg
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    50mg
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    100mg
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  • ABT-072

    CAS:
    ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.
    Formula:C24H27N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:469.55

    Ref: TM-T14086

    25mg
    1,691.00€
    50mg
    2,205.00€
    100mg
    3,345.00€
  • Valopicitabine

    CAS:
    Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic
    Formula:C15H24N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:356.37

    Ref: TM-T13281

    25mg
    2,547.00€
    50mg
    3,861.00€
    100mg
    4,599.00€
  • Odiparcil

    CAS:
    Odiparcil is an orally active beta-d-thioxyloside analog.
    Formula:C15H16O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.35

    Ref: TM-T16377

    2mg
    161.00€
    25mg
    690.00€
    50mg
    897.00€
    100mg
    1,386.00€
  • Marizomib

    CAS:
    Marizomib is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L, CT-T-laspase-like, and trypsin-like 20S proteasomes.Cost-effective and quality-assured.
    Formula:C15H20ClNO4
    Purity:98.03% - 99.41%
    Color and Shape:Solid
    Molecular weight:313.78

    Ref: TM-T16012

    1mg
    525.00€
    5mg
    1,121.00€
    100µg
    120.00€
    500µg
    321.00€
  • RO5461111

    CAS:
    RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) & 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation & lupus nephritis.
    Formula:C27H24F6N4O4S
    Color and Shape:Solid
    Molecular weight:614.56

    Ref: TM-T73220

    25mg
    2,942.00€
    50mg
    4,319.00€
    100mg
    To inquire