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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Z-PDLDA-NHOH

    CAS:
    <p>Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].</p>
    Formula:C22H32N4O6
    Color and Shape:Solid
    Molecular weight:448.51
  • HIV-1 protease-IN-9

    CAS:
    <p>HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and a</p>
    Formula:C37H41N7O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:679.83
  • DCLK1-IN-2

    CAS:
    <p>DCLK1-IN-2 (Compound I-5) is a potent inhibitor of DCLK1, exhibiting an IC50 of 171.3 nM, and demonstrates significant antiproliferative effects on SW1990 cell</p>
    Formula:C26H32N8O3S
    Color and Shape:Solid
    Molecular weight:536.65
  • Berotralstat HCl

    CAS:
    <p>Berotralstat HCl is a selective plasma kallikrein inhibitor, reducing pain and swelling in HAE by blocking bradykinin release.</p>
    Formula:C30H28Cl2F4N6O
    Color and Shape:Solid
    Molecular weight:635.4886
  • Z-DEVD-CMK

    CAS:
    <p>Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].</p>
    Formula:C27H35ClN4O12
    Color and Shape:Solid
    Molecular weight:643.04
  • I-XW-053

    CAS:
    <p>I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-</p>
    Formula:C22H16N2O2
    Purity:99.05%
    Color and Shape:Solid
    Molecular weight:340.37
  • O-Benzoylhydroxylamine

    CAS:
    <p>O-Benzoyl hydroxylamine exhibits properties as a dipeptidyl peptidase-IV (DPP-IV) inhibitor and demonstrates antidiabetic effects[1].</p>
    Formula:C7H7NO2
    Color and Shape:Solid
    Molecular weight:137.14
  • Kallikrein-IN-2

    CAS:
    <p>Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein.</p>
    Formula:C28H25F3N4O4
    Color and Shape:Solid
    Molecular weight:538.52
  • Neurodegenerative Disorder-Targeting Compound 1

    CAS:
    <p>Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].</p>
    Formula:C28H28N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:484.55
  • NCI-B16

    CAS:
    <p>NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].</p>
    Formula:C27H26N8O4
    Color and Shape:Solid
    Molecular weight:526.55
  • KCC009

    CAS:
    <p>KCC009 is a potent and selective Transglutaminase 2 Inhibitor.</p>
    Formula:C21H22BrN3O5
    Color and Shape:Solid
    Molecular weight:476.32
  • SQ 32056

    CAS:
    <p>SQ 32056 is a cathepsin E inhibitor.</p>
    Formula:C37H56N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:636.86
  • BMS-189664 HCl

    CAS:
    <p>BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.</p>
    Formula:C22H35ClN6O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:515.07
  • Ecallantide

    CAS:
    <p>Ecallantide (DX-88) is a recombinant inhibitor specifically targeting plasma kallikrein, which serves to impede the synthesis of bradykinin.</p>
    Formula:C305H448N88O91S8
    Color and Shape:Solid
    Molecular weight:7059.88
  • Proteasome-IN-4


    <p>Proteasome-IN-4, a potent non-covalent inhibitor (IC50=8.39nM), halts cancer cell growth, useful for oncology studies.</p>
    Formula:C44H58N6O5
    Color and Shape:Solid
    Molecular weight:750.97
  • MMP-145

    CAS:
    <p>MMP-145 is used as a protease inhibitor.</p>
    Formula:C20H20N2O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:432.45
  • HIV-1 protease-IN-8

    CAS:
    <p>HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.</p>
    Formula:C25H35N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:489.63
  • Human enteropeptidase-IN-1

    CAS:
    <p>Enteropeptidase-IN-1: orally active, potent inhibitor, low systemic exposure, for anti-obesity research.</p>
    Formula:C20H18N4O7
    Color and Shape:Solid
    Molecular weight:426.38
  • MeOSuc-AAPV-CMK

    CAS:
    <p>MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediated</p>
    Formula:C22H35ClN4O7
    Color and Shape:Solid
    Molecular weight:502.99
  • NK3201

    CAS:
    <p>NK3201, a specific chymase inhibitor, suppresses bleomycin-induced pulmonary fibrosis in hamsters.</p>
    Formula:C31H29N5O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:567.59