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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 984 products of "Proteases/Proteasome"

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  • Belactin A

    CAS:
    Belactin A acts as an inhibitor of vasohibin-1 [VASH-1] with an IC50 of 0.18 µg/ml.
    Formula:C17H21ClN2O4
    Color and Shape:Solid
    Molecular weight:352.81

    Ref: TM-T207748

    10mg
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    50mg
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  • (1R,3S)-THCCA-Asn


    (1R,3S)-THCCA-Asn (4j) is a selective inhibitor of thrombin (IC50: 0.07-0.14 μM) with anti-thrombotic effects.
    Formula:C24H24N4O6
    Color and Shape:Solid
    Molecular weight:464.47

    Ref: TM-T62949

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • RBx-0597

    CAS:
    RBx-0597 is a selective DPP-IV inhibitor with IC50 values of 32 nM, 31 nM, and 39 nM for human, mouse, and rat plasma DPP-IV, respectively. It is utilized in research focused on type 2 diabetes.
    Formula:C19H20F2N4O2
    Color and Shape:Solid
    Molecular weight:374.384

    Ref: TM-T206740

    10mg
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    50mg
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  • Tilpisertib fosmecarbil

    CAS:
    Tilpisertib fosmecarbil is a potent inhibitor of serine/threonine kinases with anti-inflammatory properties.
    Formula:C35H36ClN8O7P
    Color and Shape:Solid
    Molecular weight:747.14

    Ref: TM-T72292

    25mg
    2,853.00€
    50mg
    3,763.00€
    100mg
    5,220.00€
  • RO5461111

    CAS:
    RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) & 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation & lupus nephritis.
    Formula:C27H24F6N4O4S
    Color and Shape:Solid
    Molecular weight:614.56

    Ref: TM-T73220

    25mg
    2,942.00€
    50mg
    4,319.00€
    100mg
    To inquire
  • RJF02215

    CAS:
    RJF02215, an MMP-9 inhibitor, exhibits growth inhibitory activity against the ovarian cancer cell line SKOV3. It is utilized in tumor research.
    Formula:C17H12ClN3OS3
    Color and Shape:Solid
    Molecular weight:405.95

    Ref: TM-T89894

    10mg
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    50mg
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  • Faldaprevir sodium

    CAS:
    Faldaprevir sodium: HCV treatment, inhibits NS3/NS4A protease, P-glycoprotein, CYP3A4, UGT1A1.
    Formula:C40H48BrN6NaO9S
    Color and Shape:Solid
    Molecular weight:891.81

    Ref: TM-T71215

    25mg
    2,718.00€
    50mg
    3,582.00€
    100mg
    4,950.00€
  • Plasma kallikrein-IN-2


    Plasma kallikrein-IN-2: PKal inhibitor, IC50=0.1 nM. Used in angioedema, diabetic eye disease research.
    Formula:C28H24ClF3N8O3
    Color and Shape:Solid
    Molecular weight:612.99

    Ref: TM-T72337

    25mg
    2,718.00€
    50mg
    3,582.00€
    100mg
    4,950.00€
  • Tyrosinase-IN-37

    CAS:
    Tyrosinase-IN-37 (Compound 3c) is a potent inhibitor of tyrosinase, with an IC50 value of 1.02 μM, which is 14 times more effective than kojic acid (IC50 of 14.74 μM). This compound effectively prevents the browning of Rosa roxburghii and can also inhibit browning not caused by tyrosinase.
    Formula:C12H12N6S
    Color and Shape:Solid
    Molecular weight:272.33

    Ref: TM-T200626

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • BI-1942

    CAS:
    BI-1942 is a chymase inhibitor with an IC50 value of 0.4 nM against human chymase. It is applicable for research in ophthalmic diseases.
    Formula:C24H26N4O4
    Color and Shape:Solid
    Molecular weight:434.488

    Ref: TM-T205535

    10mg
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    50mg
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  • SD-7300

    CAS:
    SD-7300 (SC-81490) functions as an orally active inhibitor targeting MMP-2, MMP-9, and MMP-13, exhibiting potent inhibition with K_i values of 0.03, 0.01, and 0.03 nM, respectively. By inhibiting these metalloproteinases, SD-7300 effectively reduces extracellular matrix degradation by tumor cells, thereby curbing their invasion and metastasis. Additionally, this compound acts as a dose-dependent inhibitor of mouse corneal angiogenesis and prevents interleukin-1-induced degradation of bovine cartilage. SD-7300 is applicable in the study of breast cancer.
    Formula:C21H30F3N3O7S
    Color and Shape:Solid
    Molecular weight:525.54

    Ref: TM-T200306

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • BMT-052

    CAS:
    BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).
    Formula:C30H17D9F4N6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:635.61

    Ref: TM-T26871

    25mg
    2,718.00€
    50mg
    3,582.00€
    100mg
    4,950.00€
  • Cathepsin C-IN-3


    Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).
    Formula:C28H21F3N6OS
    Color and Shape:Solid
    Molecular weight:546.57

    Ref: TM-T63854

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • SD-2590 HCl

    CAS:
    SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.
    Formula:C22H26ClF3N2O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:554.96

    Ref: TM-T24775

    1mg
    148.00€
    5mg
    447.00€
  • Tyrosinase-IN-33

    CAS:
    Tyrosinase-IN-33 (compound 5), a pyridine-based compound, acts as an effective inhibitor of diphenolase activity in mushroom tyrosinase. It significantly reduces enzyme activity with an IC50 of 9.0 μM.
    Formula:C19H17NS2
    Color and Shape:Solid
    Molecular weight:323.48

    Ref: TM-T200002

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • HCV-IN-38


    Potent oral HCV inhibitor HCV-IN-38 has 15 nM EC50, 431 SI, high efficacy, and low toxicity.
    Formula:C22H24ClF3N4O4
    Color and Shape:Solid
    Molecular weight:500.9

    Ref: TM-T63396

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • SSR-182289A (Free)

    CAS:
    SSR-182289A (Free) is a thrombin inhibitor.
    Formula:C30H33F2N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:597.68

    Ref: TM-T28857

    25mg
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    50mg
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    100mg
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  • Valopicitabine

    CAS:
    Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic
    Formula:C15H24N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:356.37

    Ref: TM-T13281

    25mg
    2,547.00€
    50mg
    3,861.00€
    100mg
    4,599.00€
  • Tyrosinase-IN-35

    CAS:
    Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.
    Formula:C17H15N5OS
    Color and Shape:Solid
    Molecular weight:337.40

    Ref: TM-T200078

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • HCV NS5B polymerase-IN-2

    CAS:
    HCVNS5B polymerase-IN-2 (Compound 298) is an inhibitor of the Ns5b polymerase. It holds potential for research into the treatment of hepatitis C virus (HCV) infections.
    Formula:C26H24N2O4
    Color and Shape:Solid
    Molecular weight:428.48

    Ref: TM-T204671

    10mg
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    50mg
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