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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 992 products of "Proteases/Proteasome"

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  • Talabostat

    CAS:
    Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.
    Formula:C9H19BN2O3
    Color and Shape:Solid
    Molecular weight:214.07

    Ref: TM-T37861

    5mg
    100.00€
    10mg
    148.00€
    50mg
    545.00€
  • Ichorcumab

    CAS:

    Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.

    Color and Shape:Liquid

    Ref: TM-T9901A-779

    1mg
    To inquire
    5mg
    To inquire
  • PROTAC CG167


    PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47

    Ref: TM-T205234

    10mg
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    50mg
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  • Nitidanin


    Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.
    Formula:C21H24O8
    Color and Shape:Solid
    Molecular weight:404.415

    Ref: TM-T125599

    1mg
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    5mg
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  • 5-epi-Arvestonate A

    CAS:

    5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.

    Formula:C16H26O5
    Color and Shape:Solid
    Molecular weight:298.37

    Ref: TM-T75535

    5mg
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    50mg
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  • HCV-IN-7 hydrochloride

    CAS:
    HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.
    Formula:C40H50Cl2N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:841.85

    Ref: TM-T11548L

    25mg
    1,369.00€
  • RXP470

    CAS:
    RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).
    Formula:C35H35BrClN4O10P
    Color and Shape:Solid
    Molecular weight:818

    Ref: TM-T28633

    5mg
    4,626.00€
  • RJS308


    RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)
    Formula:C63H75N13O11S
    Color and Shape:Solid
    Molecular weight:1222.42

    Ref: TM-T205591

    10mg
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    50mg
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  • Grazoprevir potassium salt

    CAS:

    Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.

    Formula:C38H49KN6O9S
    Color and Shape:Solid
    Molecular weight:805

    Ref: TM-T19948

    50mg
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    100mg
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  • Relacatib

    CAS:
    Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.
    Formula:C27H32N4O6S
    Color and Shape:Solid
    Molecular weight:540.64

    Ref: TM-T40463

    5mg
    1,773.00€
  • VD2173

    CAS:
    VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.
    Formula:C31H45N9O6S
    Color and Shape:Solid
    Molecular weight:671.81

    Ref: TM-T74390

    5mg
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    50mg
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  • Bortezomib analog


    Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.
    Color and Shape:Odour Solid

    Ref: TM-T200528

    10mg
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    50mg
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  • HIV-1 Rev (34-50)

    CAS:
    HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity.
    Formula:C97H173N51O24
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:2437.74

    Ref: TM-TP1149

    1mg
    131.00€
    5mg
    198.00€
    10mg
    288.00€
    25mg
    452.00€
    50mg
    607.00€
    100mg
    785.00€
    200mg
    1,045.00€
  • 6,6′-Dihydroxythiobinupharidine

    CAS:
    6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-fold
    Formula:C30H42N2O4S
    Color and Shape:Solid
    Molecular weight:526.73

    Ref: TM-T79978

    5mg
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    50mg
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  • GCPII-IN-1

    CAS:

    GCPII-IN-1, a potent PSMA inhibitor, binds with 44.3 nM affinity.

    Formula:C12H21N3O7
    Color and Shape:Solid
    Molecular weight:319.314

    Ref: TM-T38420

    5mg
    922.00€
  • PSI-7409

    CAS:

    PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).

    Formula:C10H16FN2O14P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:500.16

    Ref: TM-T12572

    25mg
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    50mg
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    100mg
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  • Neutrophil elastase inhibitor 4


    Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.
    Formula:C20H21N3O5
    Color and Shape:Solid
    Molecular weight:383.4

    Ref: TM-T79397

    5mg
    To inquire
    50mg
    To inquire
  • AP-C2

    CAS:
    AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.
    Formula:C18H16N4S
    Purity:99.99%
    Color and Shape:Soild
    Molecular weight:320.41

    Ref: TM-T77570

    2mg
    38.00€
    5mg
    59.00€
    10mg
    82.00€
    25mg
    148.00€
    50mg
    245.00€
    100mg
    427.00€
    200mg
    577.00€
  • 15,16-Dihydrotanshindiol C


    15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.
    Formula:C18H18O5
    Color and Shape:Solid
    Molecular weight:314.337

    Ref: TM-T123985

    1mg
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    5mg
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  • C-telopeptide

    CAS:
    C-telopeptide from type I collagen is released during bone resorption; it correlates with bone mineral density.
    Formula:C34H56N14O13
    Purity:98%
    Color and Shape:Solid
    Molecular weight:868.9

    Ref: TM-TP1779

    1mg
    109.00€
    5mg
    424.00€
    10mg
    720.00€