
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
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Found 1045 products of "Proteases/Proteasome"
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Enantiomer of Sofosbuvir
<p>Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.</p>Formula:C22H29FN3O9PPurity:98%Color and Shape:SolidMolecular weight:529.45BI-1915
CAS:<p>BI-1915 is a selective inhibitor of Cathepsin S, with an IC50 of 17 nM. It is utilized in the research of autoimmune diseases.</p>Formula:C21H37N5O3Color and Shape:SolidMolecular weight:407.55Deleobuvir
CAS:<p>Deleobuvir(BI207127) is an inhibitor of non-nucleoside hepatitis C virus NS5B polymerase for the treatment of hepatitis C.</p>Formula:C34H33BrN6O3Color and Shape:SolidMolecular weight:653.57Plasma kallikrein-IN-2
<p>Plasma kallikrein-IN-2: PKal inhibitor, IC50=0.1 nM. Used in angioedema, diabetic eye disease research.</p>Formula:C28H24ClF3N8O3Color and Shape:SolidMolecular weight:612.99Valopicitabine dihydrochloride
CAS:<p>Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Formula:C15H25ClN4O6Color and Shape:SolidMolecular weight:392.84Cathepsin C-IN-4
<p>Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).</p>Formula:C21H14ClF3N4SColor and Shape:SolidMolecular weight:446.88SMCypI C31
<p>SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).</p>Formula:C27H30N4O2SColor and Shape:SolidMolecular weight:474.62(1R,3S)-THCCA-Asn
<p>(1R,3S)-THCCA-Asn (4j) is a selective inhibitor of thrombin (IC50: 0.07-0.14 μM) with anti-thrombotic effects.</p>Formula:C24H24N4O6Color and Shape:SolidMolecular weight:464.47RO5461111
CAS:<p>RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) & 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation & lupus nephritis.</p>Formula:C27H24F6N4O4SColor and Shape:SolidMolecular weight:614.56CE-2072
CAS:<p>CE-2072 is a synthetic host serine proteases inhibitor.</p>Formula:C33H41N5O6Purity:98%Color and Shape:SolidMolecular weight:603.71Antiplatelet agent 3
CAS:<p>Antiplatelet agent 3 (Compound K-10) is a compound with antiplatelet aggregation activity, exhibiting IC50 values of 2.55, 3.22, and 2.09 mg/mL for platelet aggregation induced by ADP, AA, and COL, respectively. It holds potential for research in cardiovascular diseases.</p>Formula:C38H32N2O5Color and Shape:SolidMolecular weight:596.671Cathepsin C-IN-3
<p>Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).</p>Formula:C28H21F3N6OSColor and Shape:SolidMolecular weight:546.57Zetomipzomib
CAS:<p>KZR-616: Immunoproteasome inhibitor targeting LMP7 (IC50: 39/57 nM) & LMP2 (IC50: 131/179 nM), potential in autoimmune disease research.</p>Formula:C30H42N4O8Color and Shape:SolidMolecular weight:586.68Human enteropeptidase-IN-2
<p>Human enteropeptidase-IN-2 is a potent inhibitor of enteropeptidase (enteropeptidase) and can be used in anti-obesity studies.</p>Formula:C20H19F3N4O7Color and Shape:SolidMolecular weight:484.38SD-2590 HCl
CAS:<p>SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.</p>Formula:C22H26ClF3N2O7SPurity:98%Color and Shape:SolidMolecular weight:554.96SBI-581
<p>SBI-581: oral, potent TAO3 inhibitor, IC50=42nM, alters TKS5α at RAB11+ vesicles, blocks invadopodia, good mouse pharmacokinetics, anti-tumor.</p>Formula:C24H21N3O2Color and Shape:SolidMolecular weight:383.44TG-2-IN-4
CAS:<p>TG-2-IN-4 (compound 8), an inhibitor of transglutaminase 2 (TG2) with an IC 50 value of less than 0.5 mM, is utilized in the study of inflammatory disorders [1].</p>Formula:C34H40N6O5Color and Shape:SolidMolecular weight:612.72Faldaprevir
CAS:<p>Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.</p>Formula:C40H49BrN6O9SPurity:99.04% - 99.19%Color and Shape:SolidMolecular weight:869.82HCV-IN-38
<p>Potent oral HCV inhibitor HCV-IN-38 has 15 nM EC50, 431 SI, high efficacy, and low toxicity.</p>Formula:C22H24ClF3N4O4Color and Shape:SolidMolecular weight:500.9SAR107375
CAS:<p>SAR107375 is a potent, orally active dual inhibitor of thrombin and factor Xa, with K_i values of 1 nM and 8 nM for factor Xa and thrombin, respectively [1].</p>Formula:C24H30ClN5O5S2Color and Shape:SolidMolecular weight:568.11

