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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 984 products of "Proteases/Proteasome"

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  • FFAGLDD


    "FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."
    Formula:C37H49N7O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:783.82

    Ref: TM-TP1545

    2mg
    71.00€
    5mg
    92.00€
    10mg
    131.00€
    25mg
    229.00€
    50mg
    343.00€
    100mg
    517.00€
  • DPP-4-IN-14


    DPP-4-IN-14 (compound 30) is an inhibitor of DPP-4, with an IC50 value of 12.82 nM.
    Formula:C33H27N7O3
    Color and Shape:Solid
    Molecular weight:569.613

    Ref: TM-T204855

    10mg
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    50mg
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  • Dutogliptin

    CAS:
    Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
    Formula:C10H20BN3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:241.10

    Ref: TM-T11128

    25mg
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    50mg
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    100mg
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  • EP 171

    CAS:
    EP 171 is a potent agonist of TP-receptors.
    Formula:C23H29FO5
    Color and Shape:Solid
    Molecular weight:404.47

    Ref: TM-T27273

    25mg
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    50mg
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    100mg
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  • AP-C2

    CAS:
    AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.
    Formula:C18H16N4S
    Purity:99.99%
    Color and Shape:Soild
    Molecular weight:320.41

    Ref: TM-T77570

    2mg
    38.00€
    5mg
    59.00€
    10mg
    82.00€
    25mg
    148.00€
    50mg
    245.00€
    100mg
    427.00€
    200mg
    577.00€
  • Bortezomib analog


    Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.
    Color and Shape:Odour Solid

    Ref: TM-T200528

    10mg
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    50mg
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  • Obtusifolin-2-O-glucoside

    CAS:
    Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].
    Formula:C22H22O10
    Color and Shape:Solid
    Molecular weight:446.4

    Ref: TM-T75572

    5mg
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    50mg
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  • Calpain Inhibitor-1

    CAS:
    Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.
    Formula:C19H17FN6O5S
    Color and Shape:Solid
    Molecular weight:460.44

    Ref: TM-T38931

    5mg
    3,780.00€
  • Tyrosinase-IN-36


    Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.
    Color and Shape:Odour Solid

    Ref: TM-T200699

    10mg
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    50mg
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  • RXP470

    CAS:
    RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).
    Formula:C35H35BrClN4O10P
    Color and Shape:Solid
    Molecular weight:818

    Ref: TM-T28633

    5mg
    4,626.00€
  • midesteine

    CAS:
    Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.
    Formula:C12H13NO3S3
    Purity:99.87% - 99.98%
    Color and Shape:Solid
    Molecular weight:315.43

    Ref: TM-T68099

    1mg
    50.00€
    5mg
    111.00€
    10mg
    165.00€
    25mg
    266.00€
    50mg
    379.00€
    100mg
    540.00€
    200mg
    757.00€
  • PSI-353661

    CAS:
    PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.
    Formula:C24H32FN6O8P
    Color and Shape:Solid
    Molecular weight:582.52

    Ref: TM-T74301

    5mg
    To inquire
    50mg
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  • STK33-IN-1

    CAS:
    STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.
    Formula:C24H27N7O2
    Color and Shape:Solid
    Molecular weight:445.527

    Ref: TM-T38835

    5mg
    873.00€
  • HCV-IN-7 hydrochloride

    CAS:
    HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.
    Formula:C40H50Cl2N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:841.85

    Ref: TM-T11548L

    25mg
    1,369.00€
  • Ichorcumab

    CAS:

    Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.

    Color and Shape:Liquid

    Ref: TM-T9901A-779

    1mg
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    5mg
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  • Relacatib

    CAS:
    Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.
    Formula:C27H32N4O6S
    Color and Shape:Solid
    Molecular weight:540.64

    Ref: TM-T40463

    5mg
    1,773.00€
  • Stevia Powder


    Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.
    Color and Shape:Odour Solid

    Ref: TM-TN8189

    10mg
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    50mg
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  • Histatin 5 (TFA)(115966-68-2,free)


    Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM
    Formula:C135H196F3N51O35
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3150.32

    Ref: TM-TP1446

    1mg
    159.00€
    5mg
    532.00€
    10mg
    832.00€
    25mg
    1,489.00€
    50mg
    2,247.00€
  • Iso-VQA-ACC acetate


    Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.
    Color and Shape:Odour Solid

    Ref: TM-TP2884

    10mg
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    50mg
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  • Phaeosphaone D

    CAS:
    Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).
    Formula:C20H27N3O3S2
    Color and Shape:Solid
    Molecular weight:421.58

    Ref: TM-T75470

    5mg
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    50mg
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