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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 987 products of "Proteases/Proteasome"

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  • Iso-VQA-ACC acetate


    Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.
    Color and Shape:Odour Solid

    Ref: TM-TP2884

    10mg
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    50mg
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  • Dutogliptin

    CAS:
    Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
    Formula:C10H20BN3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:241.10

    Ref: TM-T11128

    25mg
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    50mg
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    100mg
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  • Calpain Inhibitor-1

    CAS:
    Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.
    Formula:C19H17FN6O5S
    Color and Shape:Solid
    Molecular weight:460.44

    Ref: TM-T38931

    5mg
    3,780.00€
  • PSI-7409

    CAS:

    PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).

    Formula:C10H16FN2O14P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:500.16

    Ref: TM-T12572

    25mg
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    50mg
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    100mg
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  • Monodes(N-carboxymethyl)valine Daclatasvir

    CAS:
    Monodes(N-carboxymethyl)valine Daclatasvir, or Daclatasvir Impurity A, degrades Daclatasvir, a strong HCV NS5A inhibitor.
    Formula:C33H39N7O3
    Color and Shape:Solid
    Molecular weight:581.71

    Ref: TM-T37915

    5mg
    299.00€
    10mg
    507.00€
  • Ecallantide TFA


    Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of
    Color and Shape:Odour Solid

    Ref: TM-T82510

    5mg
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    50mg
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  • Tyrosinase-IN-38


    Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.
    Color and Shape:Odour Solid

    Ref: TM-T200602

    10mg
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    50mg
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  • midesteine

    CAS:
    Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.
    Formula:C12H13NO3S3
    Purity:99.87% - 99.98%
    Color and Shape:Solid
    Molecular weight:315.43

    Ref: TM-T68099

    1mg
    50.00€
    5mg
    111.00€
    10mg
    165.00€
    25mg
    266.00€
    50mg
    379.00€
    100mg
    540.00€
    200mg
    757.00€
  • Bortezomib analog


    Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.
    Color and Shape:Odour Solid

    Ref: TM-T200528

    10mg
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    50mg
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  • Berotralstat

    CAS:
    Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.
    Formula:C30H26F4N6O
    Color and Shape:Solid
    Molecular weight:562.56

    Ref: TM-T35869

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • Sofosbuvir impurity H


    Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir.
    Formula:C29H33FN3O10P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:633.56

    Ref: TM-T12963

    25mg
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    50mg
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    100mg
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  • Tyrosinase-IN-36


    Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.
    Color and Shape:Odour Solid

    Ref: TM-T200699

    10mg
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    50mg
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  • NVP-DPP728 dihydrochloride

    CAS:
    NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.
    Formula:C15H20Cl2N6O
    Color and Shape:Solid
    Molecular weight:371.27

    Ref: TM-T39481

    25mg
    1,369.00€
  • Ellipyrone B


    Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50
    Formula:C25H38O7
    Color and Shape:Solid
    Molecular weight:450.57

    Ref: TM-T75493

    5mg
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    50mg
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  • Alisporivir

    CAS:
    Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.
    Formula:C63H113N11O12
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:1216.64

    Ref: TM-T14180

    1mg
    177.00€
    5mg
    447.00€
    10mg
    650.00€
    25mg
    1,018.00€
    50mg
    1,369.00€
  • α 1(I) Collagen (614-639), human

    CAS:
    This is a peptide inhibitor of collagen fibrillar matrix assembly.
    Formula:C134H189N37O39
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2942.16

    Ref: TM-TP1643

    100mg
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    500mg
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  • RXP470

    CAS:
    RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).
    Formula:C35H35BrClN4O10P
    Color and Shape:Solid
    Molecular weight:818

    Ref: TM-T28633

    5mg
    4,626.00€
  • Ichorcumab

    CAS:

    Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.

    Color and Shape:Liquid

    Ref: TM-T9901A-779

    1mg
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    5mg
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  • Relacatib

    CAS:
    Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.
    Formula:C27H32N4O6S
    Color and Shape:Solid
    Molecular weight:540.64

    Ref: TM-T40463

    5mg
    1,773.00€
  • Sadopeptins B


    Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].
    Formula:C48H69N9O13S
    Color and Shape:Solid
    Molecular weight:1012.18

    Ref: TM-T75624

    5mg
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    50mg
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