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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • PF 00356231

    CAS:
    <p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>
    Formula:C25H20N2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:428.5
  • Ellipyrone A


    <p>Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).</p>
    Formula:C25H34O8
    Color and Shape:Solid
    Molecular weight:462.53
  • JC-10

    CAS:
    <p>JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.</p>
    Formula:C25H29Cl2IN4
    Purity:95%
    Color and Shape:Solid
    Molecular weight:583.34
  • HIV-1 inhibitor-6 

    CAS:
    <p>HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing</p>
    Formula:C14H10N4O4S
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:330.32
  • CRA-2059 hydrochloride


    <p>CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].</p>
    Color and Shape:Solid
  • BPHA

    CAS:
    <p>BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.</p>
    Formula:C21H20N2O4S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:396.46
  • C-telopeptide

    CAS:
    <p>C-telopeptide from type I collagen is released during bone resorption; it correlates with bone mineral density.</p>
    Formula:C34H56N14O13
    Purity:98%
    Color and Shape:Solid
    Molecular weight:868.9
  • AL-611

    CAS:
    <p>AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).</p>
    Formula:C25H33F2N6O8P
    Color and Shape:Solid
    Molecular weight:614.544
  • Cys-TAT(47-57) acetate(583836-55-9 Free base)


    <p>Cys-TAT(47-57) acetate is derived from the HIV-1 transactivating protein. Cys-TAT(47-57) acetate is an arginine rich peptide that can penetrate cells.</p>
    Formula:C69H128N34O16S
    Purity:95.1100%
    Color and Shape:Solid
    Molecular weight:1722.04
  • Ecallantide TFA


    <p>Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of</p>
    Color and Shape:Odour Solid
  • GCPII-IN-1

    CAS:
    <p>GCPII-IN-1, a potent PSMA inhibitor, binds with 44.3 nM affinity.</p>
    Formula:C12H21N3O7
    Color and Shape:Solid
    Molecular weight:319.314
  • APC-6860

    CAS:
    <p>APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.</p>
    Formula:C9H7IN2S
    Color and Shape:Solid
    Molecular weight:302.13
  • PS 915

    CAS:
    <p>PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.</p>
    Formula:C27H36ClN7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:590.08
  • N-CBZ-Phe-Arg-AMC TFA


    <p>N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.</p>
    Formula:C35H37F3N6O8
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:726.7
  • TMC647055 Choline salt


    <p>TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).</p>
    Formula:C37H53N5O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:727.91
  • KKI-5

    CAS:
    <p>KKI 5: Serine protease inhibitor, blocks kallikrein &amp; plasmin, potential for cancer therapy &amp; angioedema treatment.</p>
    Formula:C35H55N11O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:773.88
  • Linagliptin Methyldimer

    CAS:
    <p>Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.</p>
    Formula:C50H56N16O4
    Purity:97.23%
    Color and Shape:Solid
    Molecular weight:945.08
  • BAY 1217224

    CAS:
    <p>BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.</p>
    Formula:C24H27ClFN3O5
    Color and Shape:Solid
    Molecular weight:491.94
  • Ellipyrone B


    <p>Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50</p>
    Formula:C25H38O7
    Color and Shape:Solid
    Molecular weight:450.57
  • Cathepsin C-IN-6


    <p>Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase</p>
    Formula:C24H35N5O4·xC2HF3O2
    Color and Shape:Solid