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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 985 products of "Proteases/Proteasome"

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  • PF 00356231

    CAS:

    PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).

    Formula:C25H20N2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:428.5

    Ref: TM-T60071

    1mg
    185.00€
    5mg
    415.00€
    10mg
    622.00€
    25mg
    1,119.00€
    50mg
    1,679.00€
    100mg
    2,520.00€
    200mg
    3,780.00€
  • APC-6860

    CAS:
    APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.
    Formula:C9H7IN2S
    Color and Shape:Solid
    Molecular weight:302.13

    Ref: TM-T39029

    5mg
    873.00€
  • CTTHWGFTLC, CYCLIC

    CAS:
    CTT Gelatinase Inhibitor peptide blocks MMP-2/9, hindering cancer by stopping tumor growth.
    Formula:C52H71N13O14S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1166.33

    Ref: TM-TP1501

    100mg
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    500mg
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  • TP0597850

    CAS:
    TP0597850, a selective MMP2 inhibitor with an IC50 value of 0.22 nM, demonstrates a prolonged dissociation half-life from MMP2 (t1/2 = 265 minutes) [1].
    Formula:C41H57N9O13S
    Color and Shape:Solid
    Molecular weight:916.01

    Ref: TM-T74714

    5mg
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    50mg
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  • Berotralstat

    CAS:
    Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.
    Formula:C30H26F4N6O
    Color and Shape:Solid
    Molecular weight:562.56

    Ref: TM-T35869

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • Sofosbuvir impurity J

    CAS:
    Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
    Formula:C22H30FN4O8P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.47

    Ref: TM-T12965

    25mg
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    50mg
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    100mg
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  • Ac-Phe-Gly-pNA

    CAS:
    Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .
    Formula:C19H20N4O5
    Color and Shape:Solid
    Molecular weight:384.39

    Ref: TM-T74692

    5mg
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    50mg
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  • BMS-767778

    CAS:
    BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.
    Formula:C19H20Cl2N4O2
    Color and Shape:Solid
    Molecular weight:407.29

    Ref: TM-T26857

    25mg
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    50mg
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    100mg
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  • GSK2818713

    CAS:
    GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.
    Formula:C46H56N8O8
    Color and Shape:Solid
    Molecular weight:849.002

    Ref: TM-T38858

    5mg
    922.00€
  • FFAGLDD


    "FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."
    Formula:C37H49N7O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:783.82

    Ref: TM-TP1545

    2mg
    71.00€
    5mg
    92.00€
    10mg
    131.00€
    25mg
    229.00€
    50mg
    343.00€
    100mg
    517.00€
  • L 659286

    CAS:
    L 659286 is one kind of cephalosporin derivative.
    Formula:C17H21N5O7S2
    Color and Shape:Solid
    Molecular weight:471.51

    Ref: TM-T32460

    25mg
    1,369.00€
  • PS 915

    CAS:
    PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.
    Formula:C27H36ClN7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:590.08

    Ref: TM-T24674

    25mg
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    50mg
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    100mg
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  • Nostosin G


    Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).
    Formula:C25H33N5O6
    Color and Shape:Solid
    Molecular weight:499.56

    Ref: TM-T75647

    5mg
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    50mg
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  • NIM811

    CAS:
    NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.
    Formula:C62H111N11O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1202.635

    Ref: TM-T12226

    5mg
    To inquire
  • TAPI1 acetate


    TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .
    Formula:C28H41N5O7
    Purity:98.82% - 99.94%
    Color and Shape:Solid
    Molecular weight:559.65

    Ref: TM-T6009L

    1mg
    560.00€
    5mg
    1,198.00€
    10mg
    1,611.00€
    25mg
    2,385.00€
    50mg
    3,222.00€
  • Cathepsin C-IN-6


    Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase
    Formula:C24H35N5O4·xC2HF3O2
    Color and Shape:Solid

    Ref: TM-T79496

    5mg
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    50mg
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  • Aristololactam IIIa

    CAS:
    Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.
    Formula:C16H9NO4
    Color and Shape:Solid
    Molecular weight:279.25

    Ref: TM-T75619

    5mg
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    50mg
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  • Anticancer agent 114


    Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.
    Formula:C28H33BF6N2O7
    Color and Shape:Solid
    Molecular weight:634.37

    Ref: TM-T74839

    5mg
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    50mg
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  • (-)-Taxifolin

    CAS:
    (-)-Taxifolin, less active enantiomer with anti-tyrosinase, collagenase inhibition (IC50 = 193.3 μM), antifibrotic, antioxidant properties.
    Formula:C15H12O7
    Color and Shape:Solid
    Molecular weight:304.25

    Ref: TM-T38497

    25mg
    1,369.00€
  • N-CBZ-Phe-Arg-AMC

    CAS:
    Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.
    Formula:C33H36N6O6
    Purity:98%
    Color and Shape:White To Off-White Powder
    Molecular weight:612.68

    Ref: TM-TP1013

    100mg
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    500mg
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