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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • 6,6′-Dihydroxythiobinupharidine

    CAS:
    <p>6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-fold</p>
    Formula:C30H42N2O4S
    Color and Shape:Solid
    Molecular weight:526.73
  • Grazoprevir potassium salt

    CAS:
    <p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>
    Formula:C38H49KN6O9S
    Color and Shape:Solid
    Molecular weight:805
  • Ac-PAL-AMC

    CAS:
    <p>Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.</p>
    Formula:C26H34N4O6
    Color and Shape:Solid
    Molecular weight:498.57
  • Ac-VDQQD-pNA

    CAS:
    <p>Ac-VDQQD-pNA serves as a substrate for Caspase 2, which cleaves it to yield the yellow compound pNA (p-nitroaniline).</p>
    Formula:C31H43N9O14
    Color and Shape:Solid
    Molecular weight:765.73
  • Sadopeptins B


    <p>Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].</p>
    Formula:C48H69N9O13S
    Color and Shape:Solid
    Molecular weight:1012.18
  • 15,16-Dihydrotanshindiol C


    <p>15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.</p>
    Formula:C18H18O5
    Color and Shape:Solid
    Molecular weight:314.337
  • Talabostat

    CAS:
    <p>Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.</p>
    Formula:C9H19BN2O3
    Color and Shape:Solid
    Molecular weight:214.07
  • ZG36


    <p>ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrial</p>
    Color and Shape:Odour Solid
  • HIV-1 TAT (48-60) Acetate


    <p>Lilotomab (HH1) is a murine anti-CD37 antibody that can be used to synthesize anti-CD37 antibody-radionuclide couplings.</p>
    Formula:C72H135N35O18
    Purity:99.93%
    Color and Shape:Soild
    Molecular weight:1779.07
  • Phaeosphaone D

    CAS:
    <p>Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).</p>
    Formula:C20H27N3O3S2
    Color and Shape:Solid
    Molecular weight:421.58
  • Tyrosinase-IN-34


    <p>Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.</p>
    Formula:C19H14BrClN4O
    Color and Shape:Solid
    Molecular weight:429.7
  • Histatin 5 (TFA)(115966-68-2,free)


    <p>Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM</p>
    Formula:C135H196F3N51O35
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3150.32
  • NVP-DPP728 dihydrochloride

    CAS:
    <p>NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.</p>
    Formula:C15H20Cl2N6O
    Color and Shape:Solid
    Molecular weight:371.27
  • Stevia Powder


    <p>Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.</p>
    Color and Shape:Odour Solid
  • Ecallantide TFA


    <p>Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of</p>
    Color and Shape:Odour Solid
  • STK33-IN-1

    CAS:
    <p>STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.</p>
    Formula:C24H27N7O2
    Color and Shape:Solid
    Molecular weight:445.527
  • Pseudostellarin G

    CAS:
    <p>Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.</p>
    Formula:C42H56N8O9
    Color and Shape:Solid
    Molecular weight:816.94
  • Histatin 5

    CAS:
    <p>Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.</p>
    Formula:C133H195N51O33
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3036.29
  • Plasma kallikrein-IN-1

    CAS:
    <p>Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.</p>
    Formula:C23H25F2N7O
    Color and Shape:Solid
    Molecular weight:453.498
  • Zetomipzomib maleate

    CAS:
    <p>Zetomipzomib maleate (KZR-616) selectively targets LMP7/2 in immunoproteasomes, potential for autoimmune research.</p>
    Formula:C34H46N4O12
    Color and Shape:Solid
    Molecular weight:702.758