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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Lersivirine

    CAS:
    <p>Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.</p>
    Formula:C17H18N4O2
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:310.35
  • Cilastatin

    CAS:
    <p>Cilastatin (MK0791): protects imipenem from renal breakdown; inhibits leukotriene D4 metabolism.</p>
    Formula:C16H26N2O5S
    Purity:97.76% - 99.71%
    Color and Shape:Solid
    Molecular weight:358.45
  • Etravirine

    CAS:
    <p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>
    Formula:C20H15BrN6O
    Purity:97.61% - 99.74%
    Color and Shape:White To Off-White Solid
    Molecular weight:435.28
  • Thiamine disulfide

    CAS:
    <p>Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication.</p>
    Formula:C24H34N8O4S2
    Purity:99.81%
    Color and Shape:Coa
    Molecular weight:562.71
  • Darunavir Ethanolate

    CAS:
    <p>Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>
    Formula:C29H43N3O8S
    Purity:99.84% - 99.86%
    Color and Shape:Solid
    Molecular weight:593.74
  • Dabigatran Etexilate Mesylate

    CAS:
    <p>Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.</p>
    Formula:C34H41N7O5·CH4O3S
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:723.84
  • Omarigliptin

    CAS:
    <p>Omarigliptin is a potent and selective oral dipeptidyl peptidase 4 (DPP4) inhibitor with IC50 value of 1.6 nM. Cost-effective and quality-assured.</p>
    Formula:C17H20F2N4O3S
    Purity:99.68% - 99.77%
    Color and Shape:Solid
    Molecular weight:398.43
  • Y-29794 Tosylate

    CAS:
    <p>Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.</p>
    Formula:C30H42N2O4S3
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:590.86
  • JNJ0966

    CAS:
    <p>JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).</p>
    Formula:C16H16N4O2S2
    Purity:99.46% - 99.62%
    Color and Shape:Solid
    Molecular weight:360.45
  • (S,S)-TAPI-1

    CAS:
    <p>"(S,S)-TAPI-1, an isomer of TAPI-1, inhibits MMPs and TACE (ADAM17), reducing cell surface protein shedding."</p>
    Formula:C26H37N5O5
    Color and Shape:Solid
    Molecular weight:499.6
  • Darunavir

    CAS:
    <p>Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>
    Formula:C27H37N3O7S
    Purity:99.67% - 99.76%
    Color and Shape:White Amorphous Solid
    Molecular weight:547.66
  • Belnacasan

    CAS:
    <p>Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.</p>
    Formula:C24H33ClN4O6
    Purity:96.53% - 99.5%
    Color and Shape:Solid
    Molecular weight:508.99
  • Coblopasvir dihydrochloride

    CAS:
    <p>Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.</p>
    Formula:C41H52Cl2N8O8
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:855.81
  • Obefazimod

    CAS:
    <p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>
    Formula:C16H10ClF3N2O
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:338.71
  • KKI-5 acetate(97145-43-2 free base)


    <p>KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.</p>
    Formula:C37H59N11O11
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:833.95
  • Tris(4-aminophenyl)methane

    CAS:
    <p>Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.</p>
    Formula:C19H19N3
    Purity:95.73%
    Color and Shape:Beige Solid Crystalline
    Molecular weight:289.37
  • Mericitabine

    CAS:
    <p>Mericitabine (R-7128) is an HCV inhibitor that terminates RNA chains, halting replication.</p>
    Formula:C18H26FN3O6
    Purity:97.77% - 98.54%
    Color and Shape:Solid
    Molecular weight:399.41
  • L-Albizziin

    CAS:
    <p>L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.</p>
    Formula:C4H9N3O3
    Purity:99.98%
    Color and Shape:White Powder
    Molecular weight:147.13
  • XMD8-87

    CAS:
    <p>XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.</p>
    Formula:C24H27N7O2
    Purity:98.05% - 99.89%
    Color and Shape:Solid
    Molecular weight:445.52
  • Boc-Asp(OMe)-fluoromethyl ketone

    CAS:
    <p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>
    Formula:C11H18FNO5
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:263.26
  • NBD-557

    CAS:
    <p>NBD-557 is a potentially HIV-1 inhibitor.</p>
    Formula:C17H24BrN3O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:382.3
  • Alvelestat

    CAS:
    <p>Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.</p>
    Formula:C25H22F3N5O4S
    Purity:98% - >99.99%
    Color and Shape:Solid
    Molecular weight:545.53
  • Avatrombopag

    CAS:
    <p>Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation</p>
    Formula:C29H34Cl2N6O3S2
    Purity:99.01% - 99.63%
    Color and Shape:Solid
    Molecular weight:649.65
  • SU 4942

    CAS:
    <p>SU-4942 is a modulator of tyrosine kinase signaling.</p>
    Formula:C15H10BrNO
    Purity:99% - 99.32%
    Color and Shape:Solid
    Molecular weight:300.15
  • 7-Amino-4-methylcoumarin-3-acetic acid

    CAS:
    <p>7-Amino-4-methylcoumarin-3-acetic acid (7-Amino-4-methylcoumarin) is more suitable as a substrate for enteropeptidase than GD(4)K-NA.</p>
    Formula:C12H11NO4
    Purity:98.38%
    Color and Shape:Solid
    Molecular weight:233.22
  • S 3304

    CAS:
    <p>S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.</p>
    Formula:C24H20N2O4S2
    Purity:98.09%
    Color and Shape:Solid
    Molecular weight:464.56
  • HZ-1157

    CAS:
    <p>HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.</p>
    Formula:C12H16N4O
    Purity:98.23%
    Color and Shape:Solid
    Molecular weight:232.28
  • BMS-707035

    CAS:
    <p>BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.</p>
    Formula:C17H19FN4O5S
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:410.42
  • Tenofovir alafenamide

    CAS:
    <p>Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.</p>
    Formula:C21H29N6O5P
    Purity:99.68% - 99.81%
    Color and Shape:Solid
    Molecular weight:476.47
  • Velpatasvir

    CAS:
    <p>Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor.</p>
    Formula:C49H54N8O8
    Purity:99.17% - 99.83%
    Color and Shape:Solid
    Molecular weight:883
  • Paritaprevir

    CAS:
    <p>Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂,对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂,IC50为 1.31 μM。</p>
    Formula:C40H43N7O7S
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:765.88
  • XMD16-5

    CAS:
    <p>XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.</p>
    Formula:C23H24N6O2
    Purity:98.89% - 99.98%
    Color and Shape:Solid
    Molecular weight:416.48
  • Sofosbuvir

    CAS:
    <p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>
    Formula:C22H29FN3O9P
    Purity:99.77% - 99.82%
    Color and Shape:Solid
    Molecular weight:529.45
  • 4-Butylresorcinol

    CAS:
    <p>4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.</p>
    Formula:C10H14O2
    Purity:98.64% - ≥95%
    Color and Shape:Light Beige Solid Powder
    Molecular weight:166.22
  • Odanacatib

    CAS:
    <p>Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.</p>
    Formula:C25H27F4N3O3S
    Purity:98.53% - 99.53%
    Color and Shape:Solid
    Molecular weight:525.56
  • Ximelagatran

    CAS:
    <p>Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.</p>
    Formula:C24H35N5O5
    Purity:95.48% - 99.60%
    Color and Shape:Solid
    Molecular weight:473.57
  • Daclatasvir dihydrochloride

    CAS:
    <p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>
    Formula:C40H52Cl2N8O6
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:811.8
  • TAPI-1 trifluoroacetate (163847-77-6(free base))


    <p>TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.</p>
    Formula:C28H38F3N5O7
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:613.62
  • Elbasvir

    CAS:
    <p>Elbasvir (MK-8742) is an NS5A inhibitor developed for chronic HCV treatment.</p>
    Formula:C49H55N9O7
    Purity:98.95% - 99.85%
    Color and Shape:Solid
    Molecular weight:882.02
  • Ixazomib citrate

    CAS:
    <p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>
    Formula:C20H23BCl2N2O9
    Purity:98.37% - >99.99%
    Color and Shape:Solid
    Molecular weight:517.12
  • Tegobuvir

    CAS:
    <p>Tegobuvir (GS 333126) is a specific and covalent HCV NS5B polymerase inhibitor.</p>
    Formula:C25H14F7N5
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:517.4
  • Voxilaprevir

    CAS:
    <p>Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease.</p>
    Formula:C40H52F4N6O9S
    Purity:99.83% - 99.93%
    Color and Shape:Solid
    Molecular weight:868.93
  • Grazoprevir

    CAS:
    <p>Grazoprevir (MK-5172) is a protease inhibitor targeting hepatitis C virus NS3/4A used for treating chronic HCV genotypes 1 or 4 infections. Cost-effective and quality-assured.</p>
    Formula:C38H50N6O9S
    Purity:99.36% - >99.99%
    Color and Shape:Solid
    Molecular weight:766.9
  • Ac-DEVD-AMC

    CAS:
    <p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>
    Formula:C30H37N5O13
    Purity:98.20%
    Color and Shape:White Powder
    Molecular weight:675.64
  • 4-Phenoxybenzylamine

    CAS:
    <p>4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .</p>
    Formula:C13H13NO
    Purity:97.26%
    Color and Shape:Solid
    Molecular weight:199.25
  • (R)-MG-132

    CAS:
    <p>(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.</p>
    Formula:C26H41N3O5
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:475.62
  • Dolutegravir sodium

    CAS:
    <p>Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature</p>
    Formula:C20H18F2N3NaO5
    Purity:98% - 99.46%
    Color and Shape:Solid
    Molecular weight:441.36
  • Peptide T acetate(106362-32-7 free base)


    <p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>
    Formula:C37H59N9O18
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:917.91
  • CA-074 methyl ester

    CAS:
    <p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>
    Formula:C19H31N3O6
    Purity:97.26% - 99.58%
    Color and Shape:Solid
    Molecular weight:397.47
  • Letermovir

    CAS:
    <p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>
    Formula:C29H28F4N4O4
    Purity:99.85% - 99.87%
    Color and Shape:Solid
    Molecular weight:572.55