
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
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Lersivirine
CAS:<p>Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.</p>Formula:C17H18N4O2Purity:98.01%Color and Shape:SolidMolecular weight:310.35Cilastatin
CAS:<p>Cilastatin (MK0791): protects imipenem from renal breakdown; inhibits leukotriene D4 metabolism.</p>Formula:C16H26N2O5SPurity:97.76% - 99.71%Color and Shape:SolidMolecular weight:358.45Etravirine
CAS:<p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Formula:C20H15BrN6OPurity:97.61% - 99.74%Color and Shape:White To Off-White SolidMolecular weight:435.28Thiamine disulfide
CAS:<p>Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication.</p>Formula:C24H34N8O4S2Purity:99.81%Color and Shape:CoaMolecular weight:562.71Darunavir Ethanolate
CAS:<p>Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>Formula:C29H43N3O8SPurity:99.84% - 99.86%Color and Shape:SolidMolecular weight:593.74Dabigatran Etexilate Mesylate
CAS:<p>Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.</p>Formula:C34H41N7O5·CH4O3SPurity:99.91%Color and Shape:SolidMolecular weight:723.84Omarigliptin
CAS:<p>Omarigliptin is a potent and selective oral dipeptidyl peptidase 4 (DPP4) inhibitor with IC50 value of 1.6 nM. Cost-effective and quality-assured.</p>Formula:C17H20F2N4O3SPurity:99.68% - 99.77%Color and Shape:SolidMolecular weight:398.43Y-29794 Tosylate
CAS:<p>Y-29794 Tosylate (Y-29794) is an orally active, effective, and specific non-peptide-prolyl endopeptidase (PPCE) inhibitor.</p>Formula:C30H42N2O4S3Purity:99.86%Color and Shape:SolidMolecular weight:590.86JNJ0966
CAS:<p>JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).</p>Formula:C16H16N4O2S2Purity:99.46% - 99.62%Color and Shape:SolidMolecular weight:360.45(S,S)-TAPI-1
CAS:<p>"(S,S)-TAPI-1, an isomer of TAPI-1, inhibits MMPs and TACE (ADAM17), reducing cell surface protein shedding."</p>Formula:C26H37N5O5Color and Shape:SolidMolecular weight:499.6Darunavir
CAS:<p>Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>Formula:C27H37N3O7SPurity:99.67% - 99.76%Color and Shape:White Amorphous SolidMolecular weight:547.66Belnacasan
CAS:<p>Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.</p>Formula:C24H33ClN4O6Purity:96.53% - 99.5%Color and Shape:SolidMolecular weight:508.99Coblopasvir dihydrochloride
CAS:<p>Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.</p>Formula:C41H52Cl2N8O8Purity:99.33%Color and Shape:SolidMolecular weight:855.81Obefazimod
CAS:<p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>Formula:C16H10ClF3N2OPurity:99.86%Color and Shape:SolidMolecular weight:338.71KKI-5 acetate(97145-43-2 free base)
<p>KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.</p>Formula:C37H59N11O11Purity:99.44%Color and Shape:SolidMolecular weight:833.95Tris(4-aminophenyl)methane
CAS:<p>Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.</p>Formula:C19H19N3Purity:95.73%Color and Shape:Beige Solid CrystallineMolecular weight:289.37Mericitabine
CAS:<p>Mericitabine (R-7128) is an HCV inhibitor that terminates RNA chains, halting replication.</p>Formula:C18H26FN3O6Purity:97.77% - 98.54%Color and Shape:SolidMolecular weight:399.41L-Albizziin
CAS:<p>L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.</p>Formula:C4H9N3O3Purity:99.98%Color and Shape:White PowderMolecular weight:147.13XMD8-87
CAS:<p>XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.</p>Formula:C24H27N7O2Purity:98.05% - 99.89%Color and Shape:SolidMolecular weight:445.52Boc-Asp(OMe)-fluoromethyl ketone
CAS:<p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>Formula:C11H18FNO5Purity:≥98%Color and Shape:SolidMolecular weight:263.26NBD-557
CAS:<p>NBD-557 is a potentially HIV-1 inhibitor.</p>Formula:C17H24BrN3O2Purity:99.52%Color and Shape:SolidMolecular weight:382.3Alvelestat
CAS:<p>Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.</p>Formula:C25H22F3N5O4SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:545.53Avatrombopag
CAS:<p>Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation</p>Formula:C29H34Cl2N6O3S2Purity:99.01% - 99.63%Color and Shape:SolidMolecular weight:649.65SU 4942
CAS:<p>SU-4942 is a modulator of tyrosine kinase signaling.</p>Formula:C15H10BrNOPurity:99% - 99.32%Color and Shape:SolidMolecular weight:300.157-Amino-4-methylcoumarin-3-acetic acid
CAS:<p>7-Amino-4-methylcoumarin-3-acetic acid (7-Amino-4-methylcoumarin) is more suitable as a substrate for enteropeptidase than GD(4)K-NA.</p>Formula:C12H11NO4Purity:98.38%Color and Shape:SolidMolecular weight:233.22S 3304
CAS:<p>S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.</p>Formula:C24H20N2O4S2Purity:98.09%Color and Shape:SolidMolecular weight:464.56HZ-1157
CAS:<p>HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.</p>Formula:C12H16N4OPurity:98.23%Color and Shape:SolidMolecular weight:232.28BMS-707035
CAS:<p>BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.</p>Formula:C17H19FN4O5SPurity:99.78%Color and Shape:SolidMolecular weight:410.42Tenofovir alafenamide
CAS:<p>Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.</p>Formula:C21H29N6O5PPurity:99.68% - 99.81%Color and Shape:SolidMolecular weight:476.47Velpatasvir
CAS:<p>Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor.</p>Formula:C49H54N8O8Purity:99.17% - 99.83%Color and Shape:SolidMolecular weight:883Paritaprevir
CAS:<p>Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂,对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂,IC50为 1.31 μM。</p>Formula:C40H43N7O7SPurity:99.72%Color and Shape:SolidMolecular weight:765.88XMD16-5
CAS:<p>XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.</p>Formula:C23H24N6O2Purity:98.89% - 99.98%Color and Shape:SolidMolecular weight:416.48Sofosbuvir
CAS:<p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>Formula:C22H29FN3O9PPurity:99.77% - 99.82%Color and Shape:SolidMolecular weight:529.454-Butylresorcinol
CAS:<p>4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.</p>Formula:C10H14O2Purity:98.64% - ≥95%Color and Shape:Light Beige Solid PowderMolecular weight:166.22Odanacatib
CAS:<p>Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.</p>Formula:C25H27F4N3O3SPurity:98.53% - 99.53%Color and Shape:SolidMolecular weight:525.56Ximelagatran
CAS:<p>Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.</p>Formula:C24H35N5O5Purity:95.48% - 99.60%Color and Shape:SolidMolecular weight:473.57Daclatasvir dihydrochloride
CAS:<p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>Formula:C40H52Cl2N8O6Purity:99.67%Color and Shape:SolidMolecular weight:811.8TAPI-1 trifluoroacetate (163847-77-6(free base))
<p>TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.</p>Formula:C28H38F3N5O7Purity:98.06%Color and Shape:SolidMolecular weight:613.62Elbasvir
CAS:<p>Elbasvir (MK-8742) is an NS5A inhibitor developed for chronic HCV treatment.</p>Formula:C49H55N9O7Purity:98.95% - 99.85%Color and Shape:SolidMolecular weight:882.02Ixazomib citrate
CAS:<p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>Formula:C20H23BCl2N2O9Purity:98.37% - >99.99%Color and Shape:SolidMolecular weight:517.12Tegobuvir
CAS:<p>Tegobuvir (GS 333126) is a specific and covalent HCV NS5B polymerase inhibitor.</p>Formula:C25H14F7N5Purity:99.21%Color and Shape:SolidMolecular weight:517.4Voxilaprevir
CAS:<p>Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease.</p>Formula:C40H52F4N6O9SPurity:99.83% - 99.93%Color and Shape:SolidMolecular weight:868.93Grazoprevir
CAS:<p>Grazoprevir (MK-5172) is a protease inhibitor targeting hepatitis C virus NS3/4A used for treating chronic HCV genotypes 1 or 4 infections. Cost-effective and quality-assured.</p>Formula:C38H50N6O9SPurity:99.36% - >99.99%Color and Shape:SolidMolecular weight:766.9Ac-DEVD-AMC
CAS:<p>Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .</p>Formula:C30H37N5O13Purity:98.20%Color and Shape:White PowderMolecular weight:675.644-Phenoxybenzylamine
CAS:<p>4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .</p>Formula:C13H13NOPurity:97.26%Color and Shape:SolidMolecular weight:199.25(R)-MG-132
CAS:<p>(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.</p>Formula:C26H41N3O5Purity:98.45%Color and Shape:SolidMolecular weight:475.62Dolutegravir sodium
CAS:<p>Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature</p>Formula:C20H18F2N3NaO5Purity:98% - 99.46%Color and Shape:SolidMolecular weight:441.36Peptide T acetate(106362-32-7 free base)
<p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>Formula:C37H59N9O18Purity:99.47%Color and Shape:SolidMolecular weight:917.91CA-074 methyl ester
CAS:<p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>Formula:C19H31N3O6Purity:97.26% - 99.58%Color and Shape:SolidMolecular weight:397.47Letermovir
CAS:<p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>Formula:C29H28F4N4O4Purity:99.85% - 99.87%Color and Shape:SolidMolecular weight:572.55
