
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(38 products)
- Cysteine Protease(111 products)
- DPP-4(27 products)
- Glutaminase(45 products)
- HIV Protease(506 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(87 products)
- Serine Protease(54 products)
- p97(15 products)
Show 3 more subcategories
Found 986 products of "Proteases/Proteasome"
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Alvelestat
CAS:Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.Formula:C25H22F3N5O4SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:545.53Ref: TM-T3107
1mg34.00€2mg43.00€5mg56.00€10mg84.00€25mg148.00€50mg219.00€100mg349.00€500mg830.00€1mL*10mM (DMSO)74.00€Ximelagatran
CAS:Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.Formula:C24H35N5O5Purity:95.48% - 99.60%Color and Shape:SolidMolecular weight:473.57Dabigatran Etexilate Mesylate
CAS:Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.Formula:C34H41N7O5·CH4O3SPurity:99.91%Color and Shape:SolidMolecular weight:723.84Ref: TM-T5133
5mg39.00€10mg54.00€25mg71.00€50mg90.00€100mg105.00€200mg160.00€500mg227.00€1mL*10mM (DMSO)60.00€SU 4942
CAS:SU-4942 is a modulator of tyrosine kinase signaling.Formula:C15H10BrNOPurity:99% - 99.32%Color and Shape:SolidMolecular weight:300.15S 3304
CAS:S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.Formula:C24H20N2O4S2Purity:98.09%Color and Shape:SolidMolecular weight:464.56Ref: TM-T16966
1mg42.00€2mg60.00€5mg105.00€10mg170.00€25mg281.00€50mg395.00€100mg537.00€200mg725.00€1mL*10mM (DMSO)108.00€Efegatran
CAS:Efegatran is a hematologic agent and platelet aggregation inhibitor.
Formula:C21H32N6O3Color and Shape:SolidMolecular weight:416.52T-26c
CAS:T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor (IC50: 6.75 pM).Formula:C24H21N3O6SPurity:>99.99%Color and Shape:SolidMolecular weight:479.51Ref: TM-T5361
1mg46.00€2mg60.00€5mg90.00€10mg144.00€25mg236.00€50mg403.00€100mg582.00€1mL*10mM (DMSO)92.00€Bz-RS-ISer(3-Ph)-Ome
CAS:Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle.
Formula:C17H17NO4Purity:99.36% - 99.89%Color and Shape:White CrystalMolecular weight:299.32Glutaminase C-IN-1
CAS:Glutaminase C-IN-1 (Compound 968) is a Glutaminase C allosteric inhibitor.Formula:C27H27BrN2OPurity:99.68% - >99.99%Color and Shape:SolidMolecular weight:475.42Ref: TM-T3964
2mg42.00€5mg60.00€10mg87.00€25mg162.00€50mg273.00€100mg378.00€200mg557.00€1mL*10mM (DMSO)67.00€Camostat free base
CAS:Camostat (FOY 305) inhibits serine protease, treats cancer, viral infections, fibrosis, and blocks SARS-CoV, Coronavirus, and SARS-CoV-2 in studies.Formula:C20H22N4O5Color and Shape:SolidMolecular weight:398.41Samatasvir
CAS:Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.Formula:C47H48N8O6S2Purity:98.03%Color and Shape:SolidMolecular weight:885.06Ref: TM-T9567
1mg55.00€5mg116.00€10mg187.00€25mg376.00€50mg632.00€100mg1,008.00€1mL*10mM (DMSO)197.00€NM107
CAS:NM107, a ribonucleoside, inhibits HCV NS5B polymerase. It has broad antiviral properties with EC50 of 1.85 μM in wild-type cells.Formula:C10H15N3O5Purity:97.85%Color and Shape:White To Off-White PowderMolecular weight:257.24Patamostat
CAS:Patamostat (E-3123) inhibits trypsin, plasmin, and thrombin; may reduce acute pancreatitis progression. IC50: trypsin 39 nM, plasmin 950 nM, thrombin 1.9 μM.Formula:C20H20N4O4SColor and Shape:SolidMolecular weight:412.46L-006235
CAS:L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.Formula:C24H30N6O2SPurity:99.37%Color and Shape:SolidMolecular weight:466.6Ref: TM-T21616
2mg39.00€5mg60.00€10mg92.00€25mg177.00€50mg299.00€100mg432.00€200mg602.00€1mL*10mM (DMSO)62.00€Omarigliptin
CAS:Omarigliptin is a potent and selective oral dipeptidyl peptidase 4 (DPP4) inhibitor with IC50 value of 1.6 nM. Cost-effective and quality-assured.Formula:C17H20F2N4O3SPurity:99.68% - 99.77%Color and Shape:SolidMolecular weight:398.43Ref: TM-T2316
1mg38.00€2mg50.00€5mg80.00€10mg117.00€25mg200.00€50mg333.00€100mg477.00€500mg1,063.00€1mL*10mM (DMSO)131.00€UAMC00039 dihydrochloride
CAS:UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.Formula:C16H26Cl3N3OPurity:>99.99%Color and Shape:SolidMolecular weight:382.762-Cyanopyrimidine
CAS:2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)Formula:C5H3N3Purity:99.27%Color and Shape:Crystalline SolidMolecular weight:105.1Tegobuvir
CAS:Tegobuvir (GS 333126) is a specific and covalent HCV NS5B polymerase inhibitor.Formula:C25H14F7N5Purity:99.21%Color and Shape:SolidMolecular weight:517.4Ref: TM-T17029
1mg84.00€5mg177.00€10mg295.00€25mg504.00€50mg712.00€100mg982.00€1mL*10mM (DMSO)202.00€Anagliptin
CAS:Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.Formula:C19H25N7O2Purity:97.59% - 99.98%Color and Shape:SolidMolecular weight:383.45Ref: TM-T7133
1mg47.00€5mg92.00€10mg137.00€25mg224.00€50mg331.00€100mg502.00€200mg715.00€1mL*10mM (DMSO)97.00€7-Amino-4-methylcoumarin-3-acetic acid
CAS:7-Amino-4-methylcoumarin-3-acetic acid (7-Amino-4-methylcoumarin) is more suitable as a substrate for enteropeptidase than GD(4)K-NA.Formula:C12H11NO4Purity:98.38%Color and Shape:SolidMolecular weight:233.22MUN57694
CAS:MUN57694 is an inhibitor of 26S proteasome.Formula:C23H25N3O4Purity:99%Color and Shape:SolidMolecular weight:407.46Ref: TM-T9090
2mg35.00€5mg52.00€10mg86.00€25mg145.00€50mg210.00€100mg296.00€200mg414.00€1mL*10mM (DMSO)64.00€PF-00835231
CAS:PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-Formula:C24H32N4O6Purity:97.83%Color and Shape:SolidMolecular weight:472.53Ref: TM-T9458
1mg54.00€2mg77.00€5mg114.00€10mg177.00€25mg321.00€50mg482.00€100mg710.00€200mg982.00€1mL*10mM (DMSO)126.00€Tris(4-aminophenyl)methane
CAS:Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.Formula:C19H19N3Purity:95.73%Color and Shape:Beige Solid CrystallineMolecular weight:289.37Trelagliptin succinate
CAS:Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (Formula:C22H26FN5O6Purity:99.27% - 99.92%Color and Shape:SolidMolecular weight:475.47Tenofovir alafenamide hemifumarate
CAS:Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir.
Formula:C21H29N6O5PC4H4O4Purity:99.33% - 99.96%Color and Shape:SolidMolecular weight:534.51Carbobenzoxyproline
CAS:Carbobenzoxyproline (Carbobenzoxy-S-proline) is a prolidase inhibitor.Formula:C13H15NO4Purity:99.79%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:249.26SB-3CT
CAS:SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).Formula:C15H14O3S2Purity:98% - 99.38%Color and Shape:SolidMolecular weight:306.4Ref: TM-T2009
1mg46.00€2mg62.00€5mg94.00€10mg150.00€25mg234.00€50mg349.00€100mg518.00€500mg1,134.00€1mL*10mM (DMSO)94.00€Picolamine
CAS:Picolamine acts as a potential inhibitor of DPP-4.Formula:C6H8N2Purity:98.3%Color and Shape:Light Yellow LiquidMolecular weight:108.14CGS 27023A
CAS:CGS 27023A is a non-peptidic, potent, and orally active stromelysin inhibitor.Formula:C18H24ClN3O5SPurity:99.08%Color and Shape:SolidMolecular weight:429.92PSI-6206
CAS:PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.Formula:C10H13FN2O5Purity:98% - 99.79%Color and Shape:SolidMolecular weight:260.22KKI-5 acetate(97145-43-2 free base)
KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.Formula:C37H59N11O11Purity:99.44%Color and Shape:SolidMolecular weight:833.95Telaprevir
CAS:Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).Formula:C36H53N7O6Purity:96.9% - 98.89%Color and Shape:SolidMolecular weight:679.85GSK-A1
CAS:GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression.Formula:C29H27FN6O4SPurity:97.97% - 98.97%Color and Shape:SolidMolecular weight:574.63AF 399
CAS:AF 399 is a CCR4 antagonist. It reverses the tumor-promoting environment.Formula:C12H17N3O3SPurity:99.83%Color and Shape:SolidMolecular weight:283.35Ref: TM-T23646
1mg64.00€5mg129.00€10mg188.00€25mg299.00€50mg427.00€100mg575.00€200mg750.00€1mL*10mM (DMSO)124.00€Clemizole hydrochloride
CAS:Clemizole hydrochloride blocks H1 histamine receptors and inhibits HCV replication and NS4B RNA binding.Formula:C19H21Cl2N3Purity:>99.99%Color and Shape:SolidMolecular weight:362.3STK16-IN-1
CAS:STK16-IN-1 is an inhibitor of STK16 kinase (IC50: 295 nM).Formula:C17H12FN3OPurity:99.52%Color and Shape:SolidMolecular weight:293.3Batimastat
CAS:Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor.Formula:C23H31N3O4S2Purity:98.15% - 99.5%Color and Shape:SolidMolecular weight:477.64Talabostat mesylate
CAS:Talabostat mesylate (PT100): Oral DPP4 inhibitor, IC50 0.18 nM, targets tumor-linked proteins, boosts hematopoiesis.Formula:C10H23BN2O6SPurity:98% - 99.91%Color and Shape:SolidMolecular weight:310.18Darunavir Ethanolate
CAS:Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.Formula:C29H43N3O8SPurity:99.84% - 99.86%Color and Shape:SolidMolecular weight:593.74Ref: TM-T3335
5mg37.00€10mg52.00€25mg80.00€50mg111.00€100mg165.00€200mg236.00€500mg399.00€1mL*10mM (DMSO)48.00€PSI-6130
CAS:PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.Formula:C10H14FN3O4Purity:98.63% - 99.79%Color and Shape:SolidMolecular weight:259.23Ref: TM-T7607
1mg38.00€5mg94.00€10mg122.00€25mg212.00€50mg313.00€100mg457.00€200mg618.00€1mL*10mM (DMSO)73.00€HZ-1157
CAS:HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.Formula:C12H16N4OPurity:98.23%Color and Shape:SolidMolecular weight:232.28Anagliptin hydrochloride
CAS:Anagliptin (SK-0403) hydrochloride: potent, selective oral DPP-4 inhibitor; IC50: DPP-4 3.8 nM, DPP-8 68 nM, DPP-9 60 nM.Formula:C19H26ClN7O2Color and Shape:SolidMolecular weight:419.91Histatin 5 acetate
Histatin 5 acetate inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.Formula:C135H199N51O35Purity:98.72%Color and Shape:SolidMolecular weight:3096.35Diprotin A
CAS:Diprotin A (Ile-Pro-Ile) (Ile-Pro-Ile) is a dipeptidyl peptidase IV (DPP-IV) inhibitor.Formula:C17H31N3O4Purity:99.29%Color and Shape:White PowderMolecular weight:341.45Clemizole
CAS:Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.Formula:C19H20ClN3Purity:98% - 99.65%Color and Shape:SolidMolecular weight:325.84Ref: TM-T1822
1mg42.00€5mg82.00€10mg101.00€25mg152.00€50mg256.00€100mg460.00€500mg973.00€1mL*10mM (DMSO)93.00€LY 3000328
CAS:LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.Formula:C25H29FN4O5Purity:97.83% - 99.54%Color and Shape:SolidMolecular weight:484.52Ref: TM-TQ0116
1mg90.00€2mg130.00€5mg198.00€10mg263.00€25mg462.00€50mg672.00€100mg945.00€1mL*10mM (DMSO)207.00€Proteinase K
CAS:Proteinase K (Protease K) is a non-specific serine protease. Proteinase K hydrolyzes peptide bonds and is used for protein digestion. Cost-effective and quality-assured.Formula:C29H27N2O12PPurity:98%Color and Shape:SolidMolecular weight:626.511NSC 405020
CAS:NSC 405020 is a noncatalytic inhibitor of MT1-MMP.Formula:C12H15Cl2NOPurity:96.93% - 99.07%Color and Shape:SolidMolecular weight:260.16Sofosbuvir
CAS:Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatmentFormula:C22H29FN3O9PPurity:99.77% - 99.82%Color and Shape:SolidMolecular weight:529.45TAPI-1 trifluoroacetate (163847-77-6(free base))
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.Formula:C28H38F3N5O7Purity:98.06%Color and Shape:SolidMolecular weight:613.62
