Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(41 products)
- Cysteine Protease(117 products)
- DPP-4(26 products)
- Glutaminase(44 products)
- HIV Protease(473 products)
- PAI-1(27 products)
- Protease Inhibitors(49 products)
- Protease-activated Receptor(55 products)
- Proteasome(84 products)
- Serine Protease(55 products)
- p97(15 products)
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Found 895 products for "Proteases/Proteasome".
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(Arg)9 TFA (143413-47-2 free base)
CAS:(Arg)9 TFA (Peptide R9 TFA) is a cell-penetrating peptide. (Arg)9 TFA exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model.Formula:C56H111F3N36O12Purity:>99.99%Color and Shape:SolidMolecular weight:1537.71Proteinase K
CAS:Proteinase K (Protease K) is a non-specific serine protease. Proteinase K hydrolyzes peptide bonds and is used for protein digestion. Cost-effective and quality-assured.Formula:C29H27N2O12PPurity:98%Color and Shape:SolidMolecular weight:626.511Batimastat
CAS:Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor.Formula:C23H31N3O4S2Purity:98.15% - 99.5%Color and Shape:SolidMolecular weight:477.647-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS:7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a inhibitor of Hepatitis C Virus(HCV).Formula:C15H16N4Purity:99.22%Color and Shape:White SolidMolecular weight:252.31MMP-9-IN-1
CAS:MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).Formula:C16H17F2N3O3SPurity:99.21% - 99.91%Color and Shape:White SolidMolecular weight:369.39Ref: TM-T8310
2mg71.00€5mg105.00€1mL*10mM (DMSO)117.00€10mg167.00€25mg326.00€50mg497.00€100mg708.00€200mg964.00€Ximelagatran
CAS:Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.Formula:C24H35N5O5Purity:95.48% - 99.60%Color and Shape:SolidMolecular weight:473.57Ledipasvir
CAS:Ledipasvir (GS-5885) is a Hepatitis C Virus NS5A Inhibitor.Formula:C49H54F2N8O6Purity:99.96%Color and Shape:SolidMolecular weight:889Ref: TM-T6200
1mg35.00€2mg50.00€5mg74.00€10mg94.00€1mL*10mM (DMSO)94.00€25mg150.00€50mg244.00€100mg421.00€500mg964.00€Teneligliptin
CAS:Teneligliptin (MP-513), potent DPP-4 inhibitor, IC50 ~1 nM, blocks DPP-4 in human/rat plasma and recombinant forms.Formula:C22H30N6OSPurity:99.73%Color and Shape:SolidMolecular weight:426.58KP-457
CAS:KP-457 is a ADAM17 and a TNFα converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF).Formula:C21H24N2O7S2Purity:98.33%Color and Shape:SolidMolecular weight:480.56Ref: TM-T77778
1mg96.00€5mg205.00€1mL*10mM (DMSO)219.00€10mg334.00€25mg620.00€50mg982.00€100mg1,333.00€(1S,2R)-Alicapistat
CAS:(1S,2R)-Alicapistat inhibits calpains 1 and 2, shows promise for Alzheimer's, and has an IC50 of 395 nM.Formula:C25H27N3O4Purity:99.60%Color and Shape:White SolidMolecular weight:433.5Ref: TM-T60150
1mg64.00€5mg142.00€1mL*10mM (DMSO)167.00€10mg197.00€25mg299.00€50mg400.00€100mg537.00€(R)-Trolox
CAS:(R)-Trolox is a selective tyrosinase inhibitor used in food, cosmetics, and pharmaceutical products.Formula:C14H18O4Purity:99.88%Color and Shape:SolidMolecular weight:250.29PSI
CAS:PSI is a proteasome inhibitor.Formula:C32H50N4O8Purity:97% - 98.33%Color and Shape:SolidMolecular weight:618.76Danoprevir
CAS:Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).Formula:C35H46FN5O9SPurity:98% - 99.80%Color and Shape:SolidMolecular weight:731.83KZR-504
CAS:KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).Formula:C21H23N3O6Color and Shape:SolidMolecular weight:413.42Triton X-45(n=4)
CAS:Triton X-45: nonionic, low HLB surfactant, dispersible in water, high Krafft point, relevant for HCV research.Formula:C22H38O5Color and Shape:SolidMolecular weight:382.53Nelfinavir Mesylate
CAS:Formula:C32H45N3O4S·CH4O3SPurity:>97.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:663.89(-)-Gallocatechin Gallate
CAS:Formula:C22H18O11Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:458.38ALLM
CAS:ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].Formula:C19H35N3O4SPurity:98%Color and Shape:SolidMolecular weight:401.56S 2160
CAS:S 2160 is a synthetic chromogenic substrate for thrombin.Formula:C33H40N8O6Color and Shape:SolidMolecular weight:644.72HCV-IN-30
CAS:HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).Formula:C36H44N6O4Purity:99.6%Color and Shape:SolidMolecular weight:624.77Carboxypeptidase G2 (CPG2) Inhibitor
CAS:Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.Formula:C13H15NO6SPurity:99.96%Color and Shape:SolidMolecular weight:313.33Cathepsin Inhibitor 1
CAS:Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.Formula:C20H24ClN5O2Purity:99.78%Color and Shape:SolidMolecular weight:401.89Ref: TM-T6015
1mg46.00€5mg90.00€1mL*10mM (DMSO)100.00€10mg144.00€25mg236.00€50mg371.00€100mg522.00€200mg743.00€MMP2-IN-2
CAS:MMP2-IN-2 is an MMP-2 inhibitor that inhibits MMP-13, MMP-9, and MMP-8, and can be used in the study of cancer and immune diseases.Formula:C13H8N4O4Purity:98.09%Color and Shape:SolidMolecular weight:284.23ER 27319 maleate
CAS:Selective inhibitor of Syk kinaseFormula:C22H24N2O5Purity:98.45%Color and Shape:Yellow SolidMolecular weight:396.44Diprotin B
CAS:Diprotin B is a dipeptidyl peptidase IV inhibitor.Formula:C16H29N3O4Purity:98%Color and Shape:SolidMolecular weight:327.42Tyrosinase-IN-4
CAS:Tyrosinase-IN-4, a potent inhibitor, has uses in skin-whitening, food preservation, cosmetics, agriculture, and medicine.Formula:C15H9ClO3Color and Shape:SolidMolecular weight:272.68MyoMed 205
CAS:MyoMed-205 is an inhibitor of MuRF1 (muscle ring finger protein 1) activity. It effectively prevents early diaphragm contractile dysfunction and atrophy following 12 hours of unilateral phrenic nerve denervation. By inhibiting MuRF1, MyoMed-205 reduces muscle protein ubiquitination and subsequent proteasome degradation. It also increases the protein levels of phosphorylated Akt (ser473), an essential signaling molecule for muscle growth and maintenance. MyoMed-205 is applicable in the research and treatment of diaphragm dysfunction and atrophy (DIDD) due to early disuse, particularly in clinical situations such as diaphragm paralysis or mechanical ventilation.Formula:C26H25N3O5SColor and Shape:SolidMolecular weight:491.56Tanomastat
CAS:Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor.Formula:C23H19ClO3SPurity:98%Color and Shape:SolidMolecular weight:410.91Gemigliptin Tartrate(911637-19-9 free base)
CAS:Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4).Formula:C22H25F8N5O8Purity:>99.99%Color and Shape:SolidMolecular weight:639.45BR351
CAS:BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).Formula:C20H25FN2O5SPurity:98%Color and Shape:SolidMolecular weight:424.49OM-189
CAS:OM-189 is a selective inhibitor of synthetic thrombin.Formula:C24H36N6O3SPurity:98%Color and Shape:SolidMolecular weight:488.65Tyrosinase-IN-1
CAS:Tyrosinase-IN-1: potent inhibitor for skin-whitening & food preservation with uses in cosmetics & medicine.Formula:C10H9N3O2S2Color and Shape:SolidMolecular weight:267.33Gü1303
CAS:Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK).Formula:C20H22N4O3Color and Shape:SolidMolecular weight:366.41ABT-770
CAS:ABT-770: an orally potent and selective MMP inhibitor, shown to reduce tumor growth in animal models.Formula:C22H22F3N3O6Color and Shape:SolidMolecular weight:481.42A-933548
CAS:A-933548: potent calpain inhibitor, selective vs. cathepsins, stable, effective in cell assays.Formula:C25H21N5O3Purity:98%Color and Shape:SolidMolecular weight:439.47SP-Chymostatin B
CAS:SP-Chymostatin B inhibits proteases like chymotrypsin and papain; less effective on human elastase; works at 100-200 μg/ml.Formula:C30H41N7O6Purity:98%Color and Shape:SolidMolecular weight:595.69DPP-IV-IN-1
CAS:DPP-IV-IN-1 is an effective inhibitor of dipeptidyl peptidase IV (DPP-IV), a serine protease (IC50: 4.6 nM).Formula:C11H18FN3O2Purity:98%Color and Shape:SolidMolecular weight:243.28(Rac)-Tanomastat
CAS:Tanomastat (BAY 12-9566) is an oral biphenyl MMP inhibitor; blocks MMP-2, -3, -9, -13, with anti-invasive and anti-metastatic properties.Formula:C23H19ClO3SColor and Shape:SolidMolecular weight:410.91GSK2793660 HCl
CAS:GSK2793660 is a irreversible covalent α,β-unsaturated amide based DPP1 inhibitor.Formula:C22H32ClN3O3Color and Shape:SolidMolecular weight:421.96Cysteine Protease inhibitor
CAS:Cysteine protease inhibitors are inhibitors of cysteine proteases. Target: Cysteine ProteaseFormula:C18H14N4OPurity:98%Color and Shape:SolidMolecular weight:302.33Elastase-IN-1
CAS:Elastase-IN-1 (Compound Q11) is a non-toxic elastase inhibitor with an IC 50 of 0.897 μM [1].Formula:C17H12N4O3Color and Shape:SolidMolecular weight:320.3Plasma kallikrein-IN-3
CAS:Plasma kallikrein-IN-3 is a potent inhibitor (IC50: 0.15 μM) used in hereditary angioedema and diabetic eye disease research.Formula:C20H23N5O2Color and Shape:SolidMolecular weight:365.43HCV-IN-3
CAS:HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor (IC50: 20 μM; Kd: 29 μM).Formula:C13H11F2NOPurity:98%Color and Shape:SolidMolecular weight:235.23Cathepsin L/S-IN-1
Cathepsin L/S-IN-1 inhibits Cathepsin L & S (IC50: 4.10 & 1.79 μM) and reduces metastasis in pancreatic cancer cells.Formula:C29H33BrN4O4SColor and Shape:SolidMolecular weight:613.57Ro 09-1679
CAS:Ro 09-1679 is a thrombin inhibitor.Formula:C22H39N9O6Purity:98%Color and Shape:SolidMolecular weight:525.6JPM-OEt
CAS:JPM-OEt: broad-spectrum, covalent cysteine cathepsin inhibitor with antitumor effects.Formula:C20H28N2O6Purity:98%Color and Shape:SolidMolecular weight:392.45Grazoprevir sodium salt
CAS:Grazoprevir sodium salt is a selective Hepatitis C virus NS3/4a protease inhibitor with broad activity across genotypes and resistant variants.Formula:C38H50N6NaO9SPurity:98%Color and Shape:SolidMolecular weight:789.9Prodipine hydrochloride
CAS:Prodipine hydrochloride for purified and plasma Dipeptidyl peptidase IV (DPP IV) from the rabbit (IC50 of 4.5 μM and 30 μM, respectively).Formula:C20H26ClNPurity:98%Color and Shape:SolidMolecular weight:315.88DTS
CAS:DTS is a selective and isoform-specific RSK1 kinase inhibitor. It also has broad cancer therapeutic potential.Formula:C14H14S3Purity:98%Color and Shape:SolidMolecular weight:278.46Cyclophilin inhibitor 3
CAS:Cyclophilin inhibitor 3 (compound 7c), a potent inhibitor of cyclophilin A (CypA), exhibited potent anti-HCV effects with an EC50 value of 4.2 μM.Formula:C34H38N4O6Color and Shape:SolidMolecular weight:598.69
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