
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(38 products)
- Cysteine Protease(111 products)
- DPP-4(24 products)
- Glutaminase(44 products)
- HIV Protease(505 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(89 products)
- Serine Protease(54 products)
- p97(15 products)
Show 3 more subcategories
Found 987 products of "Proteases/Proteasome"
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ABT-770
CAS:ABT-770: an orally potent and selective MMP inhibitor, shown to reduce tumor growth in animal models.Formula:C22H22F3N3O6Color and Shape:SolidMolecular weight:481.42Antiviral agent 30
CAS:Antiviral Agent 30 (Example 118) is an active compound against HCV and RSV with an inhibitory concentration (IC 50) of greater than 25μM [1].Formula:C21H32N2O3SColor and Shape:SolidMolecular weight:392.56A-933548
CAS:A-933548: potent calpain inhibitor, selective vs. cathepsins, stable, effective in cell assays.Formula:C25H21N5O3Purity:98%Color and Shape:SolidMolecular weight:439.47SP-Chymostatin B
CAS:SP-Chymostatin B inhibits proteases like chymotrypsin and papain; less effective on human elastase; works at 100-200 μg/ml.Formula:C30H41N7O6Purity:98%Color and Shape:SolidMolecular weight:595.69DPP-IV-IN-1
CAS:DPP-IV-IN-1 is an effective inhibitor of dipeptidyl peptidase IV (DPP-IV), a serine protease (IC50: 4.6 nM).Formula:C11H18FN3O2Purity:98%Color and Shape:SolidMolecular weight:243.28(Rac)-Tanomastat
CAS:Tanomastat (BAY 12-9566) is an oral biphenyl MMP inhibitor; blocks MMP-2, -3, -9, -13, with anti-invasive and anti-metastatic properties.Formula:C23H19ClO3SColor and Shape:SolidMolecular weight:410.91GSK2793660 HCl
CAS:GSK2793660 is a irreversible covalent α,β-unsaturated amide based DPP1 inhibitor.Formula:C22H32ClN3O3Color and Shape:SolidMolecular weight:421.96Cysteine Protease inhibitor
CAS:Cysteine protease inhibitors are inhibitors of cysteine proteases. Target: Cysteine ProteaseFormula:C18H14N4OPurity:98%Color and Shape:SolidMolecular weight:302.33Elastase-IN-1
CAS:Elastase-IN-1 (Compound Q11) is a non-toxic elastase inhibitor with an IC 50 of 0.897 μM [1].Formula:C17H12N4O3Color and Shape:SolidMolecular weight:320.3Plasma kallikrein-IN-3
CAS:Plasma kallikrein-IN-3 is a potent inhibitor (IC50: 0.15 μM) used in hereditary angioedema and diabetic eye disease research.Formula:C20H23N5O2Color and Shape:SolidMolecular weight:365.43HCV-IN-3
CAS:HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor (IC50: 20 μM; Kd: 29 μM).Formula:C13H11F2NOPurity:98%Color and Shape:SolidMolecular weight:235.23Cathepsin L/S-IN-1
Cathepsin L/S-IN-1 inhibits Cathepsin L & S (IC50: 4.10 & 1.79 μM) and reduces metastasis in pancreatic cancer cells.Formula:C29H33BrN4O4SColor and Shape:SolidMolecular weight:613.57Ro 09-1679
CAS:Ro 09-1679 is a thrombin inhibitor.Formula:C22H39N9O6Purity:98%Color and Shape:SolidMolecular weight:525.6JPM-OEt
CAS:JPM-OEt: broad-spectrum, covalent cysteine cathepsin inhibitor with antitumor effects.Formula:C20H28N2O6Purity:98%Color and Shape:SolidMolecular weight:392.45Grazoprevir sodium salt
CAS:Grazoprevir sodium salt is a selective Hepatitis C virus NS3/4a protease inhibitor with broad activity across genotypes and resistant variants.Formula:C38H50N6NaO9SPurity:98%Color and Shape:SolidMolecular weight:789.9Prodipine hydrochloride
CAS:Prodipine hydrochloride for purified and plasma Dipeptidyl peptidase IV (DPP IV) from the rabbit (IC50 of 4.5 μM and 30 μM, respectively).Formula:C20H26ClNPurity:98%Color and Shape:SolidMolecular weight:315.88DTS
CAS:DTS is a selective and isoform-specific RSK1 kinase inhibitor. It also has broad cancer therapeutic potential.Formula:C14H14S3Purity:98%Color and Shape:SolidMolecular weight:278.46Cyclophilin inhibitor 3
CAS:Cyclophilin inhibitor 3 (compound 7c), a potent inhibitor of cyclophilin A (CypA), exhibited potent anti-HCV effects with an EC50 value of 4.2 μM.Formula:C34H38N4O6Color and Shape:SolidMolecular weight:598.69Desirudin
CAS:Desirudin (CGP 39393) inhibits thrombin, prevents thrombosis, and is used in thrombocytopenia research.Color and Shape:SolidAA9 TG2 inhibitor
CAS:AA9 is a novel transglutaminase (TG2) inhibitor.Formula:C32H36N4O5Color and Shape:SolidMolecular weight:556.65STOCK2S-26016
CAS:WNK-IN-B, a cell-permeable diaminoacridine, selectively inhibits WNK signaling in mpkDCT/MOVAS by targeting SPAK/OSR1 CCT domain.Formula:C20H19N3O2Color and Shape:SolidMolecular weight:333.38Desethyl KBT-3022
CAS:Desethyl KBT-3022 is an active metabolite of the antiplatelet compound KBT-3022.Formula:C23H20N2O4SPurity:98%Color and Shape:SolidMolecular weight:420.48IMB-26
CAS:IMB-26 is an HCV inhibitor (EC50: 2.1 μM) and has shown potent anti-HCV effects.Formula:C20H23BrN2O6Color and Shape:SolidMolecular weight:467.31MDL-101146, (S)-
CAS:MDL-101146, (S)- is an effective orally active inhibitor of human neutrophil elastase.Formula:C29H37F5N4O6Purity:98%Color and Shape:SolidMolecular weight:632.62U 27391
CAS:U 27391 is a metalloproteinase inhibitor. It acts by inhibits the action of human recombinant interleukin-1beta and glycosaminoglycan synthesis.Formula:C23H36N4O5Purity:98%Color and Shape:SolidMolecular weight:448.56LB-30057
CAS:LB-30057 is used as an oral thrombin inhibitor.Formula:C26H31N5O3SPurity:98%Color and Shape:SolidMolecular weight:493.62BMS-986094
CAS:INX 08189 is an RNA-directed RNA polymerase (NS5B) inhibitor.Formula:C30H39N6O9PColor and Shape:SolidMolecular weight:658.64FK-448 Free base
CAS:FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM.Formula:C25H30N2O3Purity:98%Color and Shape:SolidMolecular weight:406.52KIN1400
CAS:KIN1400 activates IRF3, boosts antiviral immunity, stimulates IFNbeta, and inhibits WNV, DV, and HCV.Formula:C24H17F2N3O2SPurity:98%Color and Shape:SolidMolecular weight:449.47HCV-IN-37
CAS:HCV-IN-37: potent HCV inhibitor, stable in rat plasma post-oral dose (15 mg/kg), blocks virus entry phase.Formula:C31H35F2N5Color and Shape:SolidMolecular weight:515.64LY 135305
CAS:LY 135305 is a inhibition of spontaneous metastasis.Formula:C19H20ClNPurity:98%Color and Shape:SolidMolecular weight:297.82Thrombin inhibitor 6
CAS:Thrombin Inhibitor 6, with an IC 50 of 1 nM, acts as a potent anticoagulant by inhibiting thrombin.Formula:C18H19ClN4O2SColor and Shape:SolidMolecular weight:390.89Ono-3307 mesylate
CAS:no-3307 mesylate is a protease inhibitor that inhibits a variety of proteases and may be used to study pancreatitis.Formula:C15H18N4O7S2Purity:97.60% - 98.16%Color and Shape:SolidMolecular weight:430.46RS-104966
CAS:RS-104966 is an inhibitor of collagenase that acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1.Formula:C19H21NO6SPurity:98%Color and Shape:SolidMolecular weight:391.44BR351 precursor
CAS:BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).Formula:C27H32N2O8S2Purity:98%Color and Shape:SolidMolecular weight:576.68WNK-IN-7
CAS:WNK-IN-7 is a potent and selective WNK1 kinase inhibitor.Formula:C26H29N3OPurity:98%Color and Shape:SolidMolecular weight:399.53BAY-678 racemate
CAS:BAY-678 racemate: orally active, selective cell-permeable HNE inhibitor with IC50 of 20 nM.Formula:C20H15F3N4O2Purity:98%Color and Shape:SolidMolecular weight:400.35PTIQ
CAS:MMP-3 expression inhibitorFormula:C13H17NO3Purity:98%Color and Shape:SolidMolecular weight:235.28K 579
CAS:K 579 is a dipeptidyl peptidase IV inhibitor.Formula:C17H24N6OPurity:98%Color and Shape:SolidMolecular weight:328.41TNK2-IN-1
CAS:TNK2-IN-1 is a TNK2 inhibitor (IC50: 224 nM) that can be used in cancer research.Formula:C23H24N6O2Color and Shape:SolidMolecular weight:416.48GSK-2793660
CAS:GSK-2793660, an oral, irreversible CTSC inhibitor, aids bronchiectasis research.Formula:C20H27N3O3Purity:98%Color and Shape:SolidMolecular weight:357.45Epostatin
CAS:Epostatin is a new dipeptidyl peptidase II (DPP-II, EC 3.4.14.2) inhibitor.Formula:C23H33N3O5Purity:98%Color and Shape:SolidMolecular weight:431.53WAY-151693
CAS:WAY-151693 is an inhibitor of human collagenase-3 (MMP-13).Formula:C21H22ClN3O5SColor and Shape:SolidMolecular weight:463.93Nucleoside-Analog-1
CAS:Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.Formula:C9H9N5O5Purity:98%Color and Shape:SolidMolecular weight:267.2YM-53601
CAS:YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.Formula:C21H22ClFN2OPurity:99.65%Color and Shape:SolidMolecular weight:372.86ND-336
CAS:ND-336 selectively inhibits MMP-2, MMP-9, MMP-14, boosts diabetic wound healing, reduces inflammation, and promotes angiogenesis and skin repair.Formula:C16H18ClNO3S2Color and Shape:SolidMolecular weight:371.9Bz-D-Arg-pNA hydrochloride
CAS:Bz-D-Arg-pNA hydrochloride is a competitive trypsin inhibitor.Formula:C19H23ClN6O4Color and Shape:SolidMolecular weight:434.88NVP DPP 728 dihydrochloride
CAS:NVP-DPP728 is a reversible DPP-IV inhibitor with a K i of 11 nM, enhancing insulin release by preventing GLP-1 degradation, used for diabetes research.Formula:C15H18N6OColor and Shape:SolidMolecular weight:298.34GLS1 Inhibitor
CAS:GLS1 inhibitor blocks glutaminase 1 (IC50=0.021 μM), hinders NCI H1703 NSCLC cell growth in vitro (GI50=0.011 μM), and suppresses tumors in mice.Formula:C19H21N7O2SColor and Shape:SolidMolecular weight:411.48Nucleoside-Analog-2
CAS:Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.Formula:C9H11N5O6Purity:98%Color and Shape:SolidMolecular weight:285.21
