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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)


    <p>CTTHWGFTLC, CYCLIC acetate is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9.</p>
    Formula:C54H75N13O16S2
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:1226.39
  • Dabigatran

    CAS:
    <p>Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.</p>
    Formula:C25H25N7O3
    Purity:97.44% - 98.7%
    Color and Shape:Tan Solid
    Molecular weight:471.51
  • CeMMEC13

    CAS:
    <p>CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).</p>
    Formula:C19H16N2O4
    Purity:98.52%
    Color and Shape:Solid
    Molecular weight:336.34
  • Doravirine

    CAS:
    <p>Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.</p>
    Formula:C17H11ClF3N5O3
    Purity:99.65% - 99.79%
    Color and Shape:Solid
    Molecular weight:425.75
  • L-Albizziin

    CAS:
    <p>L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.</p>
    Formula:C4H9N3O3
    Purity:99.98%
    Color and Shape:White Powder
    Molecular weight:147.13
  • Anagliptin

    CAS:
    <p>Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.</p>
    Formula:C19H25N7O2
    Purity:97.59% - 99.98%
    Color and Shape:Solid
    Molecular weight:383.45
  • P-113 acetate


    <p>P-113 acetate: AMP from histatin 5, treats gingivitis and HIV-related oral candidiasis safely and effectively.</p>
    Formula:C73H114N28O15
    Purity:97.4%
    Color and Shape:Solid
    Molecular weight:1623.86
  • Samatasvir

    CAS:
    <p>Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.</p>
    Formula:C47H48N8O6S2
    Purity:98.03%
    Color and Shape:Solid
    Molecular weight:885.06
  • Glutaminase C-IN-1

    CAS:
    <p>Glutaminase C-IN-1 (Compound 968) is a Glutaminase C allosteric inhibitor.</p>
    Formula:C27H27BrN2O
    Purity:99.68% - >99.99%
    Color and Shape:Solid
    Molecular weight:475.42
  • 2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-

    CAS:
    <p>2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine</p>
    Formula:C13H16O3
    Purity:99.53% - 99.81%
    Color and Shape:Solid
    Molecular weight:220.26
  • Ixazomib

    CAS:
    <p>Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.</p>
    Formula:C14H19BCl2N2O4
    Purity:98% - 98.92%
    Color and Shape:Solid
    Molecular weight:361.03
  • Batimastat

    CAS:
    <p>Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor.</p>
    Formula:C23H31N3O4S2
    Purity:98.15% - 99.5%
    Color and Shape:Solid
    Molecular weight:477.64
  • Elvitegravir

    CAS:
    <p>Elvitegravir (JTK-303) is an HIV integrase inhibitor and CYP2C9 inducer.</p>
    Formula:C23H23ClFNO5
    Purity:98.43% - 99.57%
    Color and Shape:Solid
    Molecular weight:447.88
  • Telaprevir

    CAS:
    <p>Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).</p>
    Formula:C36H53N7O6
    Purity:96.9% - 98.89%
    Color and Shape:Solid
    Molecular weight:679.85
  • 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride

    CAS:
    <p>4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is an inhibitor of HIV-1 RT (HIV reverse transcriptase) .</p>
    Formula:C8H6Cl2F3NO
    Purity:97.15%
    Color and Shape:Solid
    Molecular weight:260.04
  • Ceritinib

    CAS:
    <p>Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.</p>
    Formula:C28H36ClN5O3S
    Purity:98.52% - 99.77%
    Color and Shape:Solid
    Molecular weight:558.14
  • CGS 27023A

    CAS:
    <p>CGS 27023A is a non-peptidic, potent, and orally active stromelysin inhibitor.</p>
    Formula:C18H24ClN3O5S
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:429.92
  • Picolamine

    CAS:
    <p>Picolamine acts as a potential inhibitor of DPP-4.</p>
    Formula:C6H8N2
    Purity:98.3%
    Color and Shape:Light Yellow Liquid
    Molecular weight:108.14
  • SB-3CT

    CAS:
    <p>SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).</p>
    Formula:C15H14O3S2
    Purity:98% - 99.38%
    Color and Shape:Solid
    Molecular weight:306.4
  • S-methyl-KE-298

    CAS:
    <p>S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production</p>
    Formula:C13H16O3S
    Purity:97.33%
    Color and Shape:Solid
    Molecular weight:252.33
  • Tenofovir alafenamide hemifumarate

    CAS:
    <p>Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir.</p>
    Formula:C21H29N6O5PC4H4O4
    Purity:99.33% - 99.96%
    Color and Shape:Solid
    Molecular weight:534.51
  • Trelagliptin succinate

    CAS:
    <p>Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (</p>
    Formula:C22H26FN5O6
    Purity:99.27% - 99.92%
    Color and Shape:Solid
    Molecular weight:475.47
  • Ilomastat

    CAS:
    <p>Ilomastat (GM6001) (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor.</p>
    Formula:C20H28N4O4
    Purity:97.04% - 99.51%
    Color and Shape:Solid
    Molecular weight:388.46
  • 2-Benzylsuccinic acid

    CAS:
    <p>2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is a bacterial xenobiotic metabolite.</p>
    Formula:C11H12O4
    Purity:99.01% - ≥95%
    Color and Shape:Solid
    Molecular weight:208.21
  • (R)-MG-132

    CAS:
    <p>(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.</p>
    Formula:C26H41N3O5
    Purity:98.45%
    Color and Shape:Solid
    Molecular weight:475.62
  • NBD-557

    CAS:
    <p>NBD-557 is a potentially HIV-1 inhibitor.</p>
    Formula:C17H24BrN3O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:382.3
  • Sofosbuvir

    CAS:
    <p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>
    Formula:C22H29FN3O9P
    Purity:99.77% - 99.82%
    Color and Shape:Solid
    Molecular weight:529.45
  • Vesnarinone

    CAS:
    <p>Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but</p>
    Formula:C22H25N3O4
    Purity:96.69% - 98.13%
    Color and Shape:Solid
    Molecular weight:395.45
  • Lersivirine

    CAS:
    <p>Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.</p>
    Formula:C17H18N4O2
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:310.35
  • Boceprevir

    CAS:
    <p>Boceprevir (SCH 503034), an oral HCV NS3 protease inhibitor, has a Ki of 14 nM and EC90 of 350 nM.</p>
    Formula:C27H45N5O5
    Purity:95% - 99.16%
    Color and Shape:Solid
    Molecular weight:519.68
  • Trovirdine

    CAS:
    <p>Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.</p>
    Formula:C13H13BrN4S
    Purity:98.12% - 98.50%
    Color and Shape:Solid
    Molecular weight:337.24
  • HCV-IN-31

    CAS:
    <p>HCV-IN-31 is a HCV inhibitor with an EC50/EC95 of 15.7 μM.</p>
    Formula:C12H17FN6O3
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:312.3
  • VCH-916

    CAS:
    <p>VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.</p>
    Formula:C26H36KNO4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:497.73
  • 2-PMPA

    CAS:
    <p>2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) (IC50=300 pM).</p>
    Formula:C6H11O7P
    Purity:97.4% - 99.5%
    Color and Shape:Solid
    Molecular weight:226.12
  • Bz-RS-ISer(3-Ph)-Ome

    CAS:
    <p>Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle.</p>
    Formula:C17H17NO4
    Purity:99.36% - 99.89%
    Color and Shape:White Crystal
    Molecular weight:299.32
  • Ledipasvir (acetone)

    CAS:
    <p>Ledipasvir (acetone) (GS-5885 acetone) is an HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.</p>
    Formula:C52H60F2N8O7
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:947.08
  • (R)-Trolox

    CAS:
    <p>(R)-Trolox is a selective tyrosinase inhibitor used in food, cosmetics, and pharmaceutical products.</p>
    Formula:C14H18O4
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:250.29
  • (1S,2R)-Alicapistat

    CAS:
    <p>(1S,2R)-Alicapistat inhibits calpains 1 and 2, shows promise for Alzheimer's, and has an IC50 of 395 nM.</p>
    Formula:C25H27N3O4
    Purity:99.60%
    Color and Shape:Soild
    Molecular weight:433.5
  • KP-457

    CAS:
    <p>KP-457 is a ADAM17 and a TNFα converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF).</p>
    Formula:C21H24N2O7S2
    Purity:98.33%
    Color and Shape:Solid
    Molecular weight:480.56
  • Rilpivirine HCl

    CAS:
    <p>Rilpivirine HCl (Rilpivirine hydrochloride) is an NNRTI inhibitor with antiviral activity that inhibits the HIV virus.</p>
    Formula:C22H19ClN6
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:402.88
  • Teneligliptin

    CAS:
    <p>Teneligliptin (MP-513), potent DPP-4 inhibitor, IC50 ~1 nM, blocks DPP-4 in human/rat plasma and recombinant forms.</p>
    Formula:C22H30N6OS
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:426.58
  • Methylchloroisothiazolinone/Methylisothiazolinone Mixture

    CAS:
    <p>Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW),a preservative, activates MMPs in human bronchial epithelial cells.</p>
    Formula:C8H9ClN2O2S2
    Color and Shape:Solid
    Molecular weight:264.75
  • Sitagliptin phosphate monohydrate

    CAS:
    <p>Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.</p>
    Formula:C16H15F6N5O·H3PO4·H2O
    Purity:99.85% - 99.98%
    Color and Shape:White Or Almost White Crystalline Powder
    Molecular weight:523.33
  • Ledipasvir

    CAS:
    <p>Ledipasvir (GS-5885) is a Hepatitis C Virus NS5A Inhibitor.</p>
    Formula:C49H54F2N8O6
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:889
  • Nelfinavir

    CAS:
    <p>Nelfinavir (AG1341), with Ki=2 nM, is an HIV treatment and broad-spectrum anticancer drug.</p>
    Formula:C32H45N3O4S
    Purity:98.16% - 99.5%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:567.78
  • PSI

    CAS:
    <p>PSI is a proteasome inhibitor.</p>
    Formula:C32H50N4O8
    Purity:97% - 98.33%
    Color and Shape:Solid
    Molecular weight:618.76
  • Danoprevir

    CAS:
    <p>Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).</p>
    Formula:C35H46FN5O9S
    Purity:98% - 99.35%
    Color and Shape:Solid
    Molecular weight:731.83
  • Triton X-45(n=4)

    CAS:
    <p>Triton X-45: nonionic, low HLB surfactant, dispersible in water, high Krafft point, relevant for HCV research.</p>
    Formula:C22H38O5
    Color and Shape:Solid
    Molecular weight:382.53
  • Lanadelumab

    CAS:
    <p>Lanadelumab (SHP643), a humanized IgG1 antibody, inhibits plasma kallikrein and its interaction with HMWK, supporting hereditary angioedema research.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • KZR-504

    CAS:
    <p>KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).</p>
    Formula:C21H23N3O6
    Color and Shape:Solid
    Molecular weight:413.42