
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
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CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)
<p>CTTHWGFTLC, CYCLIC acetate is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9.</p>Formula:C54H75N13O16S2Purity:99.71%Color and Shape:SolidMolecular weight:1226.39Dabigatran
CAS:<p>Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.</p>Formula:C25H25N7O3Purity:97.44% - 98.7%Color and Shape:Tan SolidMolecular weight:471.51CeMMEC13
CAS:<p>CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).</p>Formula:C19H16N2O4Purity:98.52%Color and Shape:SolidMolecular weight:336.34Doravirine
CAS:<p>Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.</p>Formula:C17H11ClF3N5O3Purity:99.65% - 99.79%Color and Shape:SolidMolecular weight:425.75L-Albizziin
CAS:<p>L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.</p>Formula:C4H9N3O3Purity:99.98%Color and Shape:White PowderMolecular weight:147.13Anagliptin
CAS:<p>Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.</p>Formula:C19H25N7O2Purity:97.59% - 99.98%Color and Shape:SolidMolecular weight:383.45P-113 acetate
<p>P-113 acetate: AMP from histatin 5, treats gingivitis and HIV-related oral candidiasis safely and effectively.</p>Formula:C73H114N28O15Purity:97.4%Color and Shape:SolidMolecular weight:1623.86Samatasvir
CAS:<p>Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.</p>Formula:C47H48N8O6S2Purity:98.03%Color and Shape:SolidMolecular weight:885.06Glutaminase C-IN-1
CAS:<p>Glutaminase C-IN-1 (Compound 968) is a Glutaminase C allosteric inhibitor.</p>Formula:C27H27BrN2OPurity:99.68% - >99.99%Color and Shape:SolidMolecular weight:475.422,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-
CAS:<p>2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine</p>Formula:C13H16O3Purity:99.53% - 99.81%Color and Shape:SolidMolecular weight:220.26Ixazomib
CAS:<p>Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.</p>Formula:C14H19BCl2N2O4Purity:98% - 98.92%Color and Shape:SolidMolecular weight:361.03Batimastat
CAS:<p>Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor.</p>Formula:C23H31N3O4S2Purity:98.15% - 99.5%Color and Shape:SolidMolecular weight:477.64Elvitegravir
CAS:<p>Elvitegravir (JTK-303) is an HIV integrase inhibitor and CYP2C9 inducer.</p>Formula:C23H23ClFNO5Purity:98.43% - 99.57%Color and Shape:SolidMolecular weight:447.88Telaprevir
CAS:<p>Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).</p>Formula:C36H53N7O6Purity:96.9% - 98.89%Color and Shape:SolidMolecular weight:679.854-Chloro-2-(trifluoroacetyl)aniline hydrochloride
CAS:<p>4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is an inhibitor of HIV-1 RT (HIV reverse transcriptase) .</p>Formula:C8H6Cl2F3NOPurity:97.15%Color and Shape:SolidMolecular weight:260.04Ceritinib
CAS:<p>Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C28H36ClN5O3SPurity:98.52% - 99.77%Color and Shape:SolidMolecular weight:558.14CGS 27023A
CAS:<p>CGS 27023A is a non-peptidic, potent, and orally active stromelysin inhibitor.</p>Formula:C18H24ClN3O5SPurity:99.08%Color and Shape:SolidMolecular weight:429.92Picolamine
CAS:<p>Picolamine acts as a potential inhibitor of DPP-4.</p>Formula:C6H8N2Purity:98.3%Color and Shape:Light Yellow LiquidMolecular weight:108.14SB-3CT
CAS:<p>SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).</p>Formula:C15H14O3S2Purity:98% - 99.38%Color and Shape:SolidMolecular weight:306.4S-methyl-KE-298
CAS:<p>S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production</p>Formula:C13H16O3SPurity:97.33%Color and Shape:SolidMolecular weight:252.33Tenofovir alafenamide hemifumarate
CAS:<p>Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir.</p>Formula:C21H29N6O5PC4H4O4Purity:99.33% - 99.96%Color and Shape:SolidMolecular weight:534.51Trelagliptin succinate
CAS:<p>Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (</p>Formula:C22H26FN5O6Purity:99.27% - 99.92%Color and Shape:SolidMolecular weight:475.47Ilomastat
CAS:<p>Ilomastat (GM6001) (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor.</p>Formula:C20H28N4O4Purity:97.04% - 99.51%Color and Shape:SolidMolecular weight:388.462-Benzylsuccinic acid
CAS:<p>2-Benzylsuccinic acid (DL-Benzylsuccinic acid) is a bacterial xenobiotic metabolite.</p>Formula:C11H12O4Purity:99.01% - ≥95%Color and Shape:SolidMolecular weight:208.21(R)-MG-132
CAS:<p>(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.</p>Formula:C26H41N3O5Purity:98.45%Color and Shape:SolidMolecular weight:475.62NBD-557
CAS:<p>NBD-557 is a potentially HIV-1 inhibitor.</p>Formula:C17H24BrN3O2Purity:99.52%Color and Shape:SolidMolecular weight:382.3Sofosbuvir
CAS:<p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>Formula:C22H29FN3O9PPurity:99.77% - 99.82%Color and Shape:SolidMolecular weight:529.45Vesnarinone
CAS:<p>Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but</p>Formula:C22H25N3O4Purity:96.69% - 98.13%Color and Shape:SolidMolecular weight:395.45Lersivirine
CAS:<p>Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.</p>Formula:C17H18N4O2Purity:98.01%Color and Shape:SolidMolecular weight:310.35Boceprevir
CAS:<p>Boceprevir (SCH 503034), an oral HCV NS3 protease inhibitor, has a Ki of 14 nM and EC90 of 350 nM.</p>Formula:C27H45N5O5Purity:95% - 99.16%Color and Shape:SolidMolecular weight:519.68Trovirdine
CAS:<p>Trovirdine (LY300046) is a thiourea non-nucleoside reverse transcriptase inhibitor.</p>Formula:C13H13BrN4SPurity:98.12% - 98.50%Color and Shape:SolidMolecular weight:337.24HCV-IN-31
CAS:<p>HCV-IN-31 is a HCV inhibitor with an EC50/EC95 of 15.7 μM.</p>Formula:C12H17FN6O3Purity:99.83%Color and Shape:SolidMolecular weight:312.3VCH-916
CAS:<p>VCH-916 is a new nonnucleoside inhibitor of HCV NS5B polymerase.</p>Formula:C26H36KNO4SPurity:98%Color and Shape:SolidMolecular weight:497.732-PMPA
CAS:<p>2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) (IC50=300 pM).</p>Formula:C6H11O7PPurity:97.4% - 99.5%Color and Shape:SolidMolecular weight:226.12Bz-RS-ISer(3-Ph)-Ome
CAS:<p>Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle.</p>Formula:C17H17NO4Purity:99.36% - 99.89%Color and Shape:White CrystalMolecular weight:299.32Ledipasvir (acetone)
CAS:<p>Ledipasvir (acetone) (GS-5885 acetone) is an HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.</p>Formula:C52H60F2N8O7Purity:99.72%Color and Shape:SolidMolecular weight:947.08(R)-Trolox
CAS:<p>(R)-Trolox is a selective tyrosinase inhibitor used in food, cosmetics, and pharmaceutical products.</p>Formula:C14H18O4Purity:99.88%Color and Shape:SolidMolecular weight:250.29(1S,2R)-Alicapistat
CAS:<p>(1S,2R)-Alicapistat inhibits calpains 1 and 2, shows promise for Alzheimer's, and has an IC50 of 395 nM.</p>Formula:C25H27N3O4Purity:99.60%Color and Shape:SoildMolecular weight:433.5KP-457
CAS:<p>KP-457 is a ADAM17 and a TNFα converting enzyme TACE inhibitor that blocks the production of soluble TNF (sTNF).</p>Formula:C21H24N2O7S2Purity:98.33%Color and Shape:SolidMolecular weight:480.56Rilpivirine HCl
CAS:<p>Rilpivirine HCl (Rilpivirine hydrochloride) is an NNRTI inhibitor with antiviral activity that inhibits the HIV virus.</p>Formula:C22H19ClN6Purity:99.48%Color and Shape:SolidMolecular weight:402.88Teneligliptin
CAS:<p>Teneligliptin (MP-513), potent DPP-4 inhibitor, IC50 ~1 nM, blocks DPP-4 in human/rat plasma and recombinant forms.</p>Formula:C22H30N6OSPurity:99.73%Color and Shape:SolidMolecular weight:426.58Methylchloroisothiazolinone/Methylisothiazolinone Mixture
CAS:<p>Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW),a preservative, activates MMPs in human bronchial epithelial cells.</p>Formula:C8H9ClN2O2S2Color and Shape:SolidMolecular weight:264.75Sitagliptin phosphate monohydrate
CAS:<p>Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.</p>Formula:C16H15F6N5O·H3PO4·H2OPurity:99.85% - 99.98%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:523.33Ledipasvir
CAS:<p>Ledipasvir (GS-5885) is a Hepatitis C Virus NS5A Inhibitor.</p>Formula:C49H54F2N8O6Purity:99.96%Color and Shape:SolidMolecular weight:889Nelfinavir
CAS:<p>Nelfinavir (AG1341), with Ki=2 nM, is an HIV treatment and broad-spectrum anticancer drug.</p>Formula:C32H45N3O4SPurity:98.16% - 99.5%Color and Shape:White To Off-White Crystalline PowderMolecular weight:567.78PSI
CAS:<p>PSI is a proteasome inhibitor.</p>Formula:C32H50N4O8Purity:97% - 98.33%Color and Shape:SolidMolecular weight:618.76Danoprevir
CAS:<p>Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).</p>Formula:C35H46FN5O9SPurity:98% - 99.35%Color and Shape:SolidMolecular weight:731.83Triton X-45(n=4)
CAS:<p>Triton X-45: nonionic, low HLB surfactant, dispersible in water, high Krafft point, relevant for HCV research.</p>Formula:C22H38O5Color and Shape:SolidMolecular weight:382.53Lanadelumab
CAS:<p>Lanadelumab (SHP643), a humanized IgG1 antibody, inhibits plasma kallikrein and its interaction with HMWK, supporting hereditary angioedema research.</p>Purity:95% - 95%Color and Shape:LiquidKZR-504
CAS:<p>KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).</p>Formula:C21H23N3O6Color and Shape:SolidMolecular weight:413.42

