
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
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DPP-IV-IN-1
CAS:<p>DPP-IV-IN-1 is an effective inhibitor of dipeptidyl peptidase IV (DPP-IV), a serine protease (IC50: 4.6 nM).</p>Formula:C11H18FN3O2Purity:98%Color and Shape:SolidMolecular weight:243.28TNIK-IN-1
CAS:<p>TNIK-IN-1 is an inhibitor of Traf2- and Nck-interacting kinase (TNIK).</p>Formula:C19H17N5O3SPurity:98%Color and Shape:SolidMolecular weight:395.43Kallikrein 5-IN-2
CAS:<p>Kallikrein 5-IN-2 inhibits KLK5 (pIC50=7.1); may normalize skin shedding, lessen inflammation & itching.</p>Formula:C23H22N6OColor and Shape:SolidMolecular weight:398.46Diethyl pyimDC
CAS:<p>Diethyl pyimDC is an inhibitor of human collagen prolyl 4-hydroxylase 1 (CP4H1).</p>Formula:C14H15N3O4Color and Shape:SolidMolecular weight:289.29Aldumastat
CAS:<p>Aldumastat (GLPG1972) is a highly potent, specific and orally active inhibitor of ADAMTS-5.Aldumastat is used for the study of osteoarthritis of the knee.</p>Formula:C20H24F2N4O3Purity:99.87%Color and Shape:SolidMolecular weight:406.43ND-336
CAS:<p>ND-336 selectively inhibits MMP-2, MMP-9, MMP-14, boosts diabetic wound healing, reduces inflammation, and promotes angiogenesis and skin repair.</p>Formula:C16H18ClNO3S2Color and Shape:SolidMolecular weight:371.9Tyrosinase-IN-11
CAS:<p>Tyrosinase-IN-11: potent inhibitor, IC50 - 50nM/64nM (L-tyrosinase/L-dopa), antioxidant, low toxicity, for hyperpigmentation study.</p>Formula:C15H14O5Color and Shape:SolidMolecular weight:274.27MK-4882
CAS:<p>MK-4882 is an effective inhibitor of HCV NS5A.</p>Formula:C42H50N8O7Purity:98%Color and Shape:SolidMolecular weight:778.9YM-53601
CAS:<p>YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.</p>Formula:C21H22ClFN2OPurity:99.65%Color and Shape:SolidMolecular weight:372.86Gosogliptin
CAS:<p>Gosogliptin is a potent, orally active, highly selective, reversible and competitive inhibitor of DPP-4, increasing the level of intestinal GLP-1 and GIP.</p>Formula:C17H24F2N6OPurity:99.74%Color and Shape:SolidMolecular weight:366.41(R)-ND-336
CAS:<p>(R)-ND-336: potent, selective MMP-9 inhibitor (K i = 19 nM); inhibits MMP-2 (127 nM), MMP-14 (119 nM); studied for diabetic foot ulcers.</p>Formula:C16H18ClNO3S2Color and Shape:SolidMolecular weight:371.89L-873724
CAS:<p>L-873724: Selective, reversible cathepsin K inhibitor; IC50s—cat K: 0.2 nM, cat S: 178 nM, cat L: 264 nM, cat B: 5239 nM; inhibits bone resorption.</p>Formula:C23H26F3N3O3SPurity:98%Color and Shape:SolidMolecular weight:481.53JO146
CAS:<p>JO146为针对沙眼衣原体高温需要蛋白A(CtHtrA)的蛋白酶抑制剂,其对CtHtrA和人中性粒细胞弹性蛋白酶(HNE)的IC50值分别为21.86 μM和1.15 μM,可应用于细菌感染的抑制。</p>Formula:C31H44N3O7PColor and Shape:SolidMolecular weight:601.67Sortin1
CAS:<p>Sortin1, a chemical genetic-hit compound, specifically induces mislocalization of both soluble and membrane-associated vacuolar markers in plants and yeast.</p>Formula:C26H19NO6Purity:98%Color and Shape:SolidMolecular weight:441.43MDK7677
CAS:<p>MDK7677 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities.</p>Formula:C12H10N4O3Color and Shape:SolidMolecular weight:258.23Furaprofen
CAS:<p>Furaprofen is an HCV inhibitor with anti-inflammatory activity that inhibits carrageenan-induced paw edema in rats.</p>Formula:C17H14O3Purity:98.49% - 99.52%Color and Shape:SolidMolecular weight:266.29Immunoproteasome inhibitor 1
CAS:<p>Potent, reversible immunoproteasome inhibitor; Ki: β5c 1.18 μM, β1i 0.27 μM, β5i 1.91 μM; potential in treating cancer.</p>Formula:C20H26N2O4Color and Shape:SolidMolecular weight:358.43GEMSA
CAS:<p>GEMSA is a potent inhibitor of enkephalin convertase ( K i =8.8 nM) with analgesic effect[1].</p>Formula:C7H13N3O4SColor and Shape:SolidMolecular weight:235.26Cysteine Protease inhibitor hydrochloride
CAS:<p>Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor.</p>Formula:C18H15ClN4OPurity:98%Color and Shape:SolidMolecular weight:338.79GSK2793660 HCl
CAS:<p>GSK2793660 is a irreversible covalent α,β-unsaturated amide based DPP1 inhibitor.</p>Formula:C22H32ClN3O3Color and Shape:SolidMolecular weight:421.96PMPA sodium
CAS:<p>PMPA sodium is a potent and selective glutamate carboxypeptidase 2 (GCP II/N-acetylated a-linked dipeptidase/NAALADase) inhibitor.</p>Formula:C6H11Na4O7PPurity:98%Color and Shape:SolidMolecular weight:318.08Nucleoside-Analog-1
CAS:<p>Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.</p>Formula:C9H9N5O5Purity:98%Color and Shape:SolidMolecular weight:267.2AK 275
CAS:<p>AK 275 is a calpain inhibitor that prevents degradation of cytoskeletal and myelin proteins in spinal cord in vitro.</p>Formula:C20H31N3O4Color and Shape:SolidMolecular weight:377.48AZD-9684
CAS:<p>AZD-9684, a carboxypeptidase U inhibitor, is used potentially for the prevention of thrombosis.</p>Formula:C10H14N2O2SColor and Shape:SolidMolecular weight:226.3CAA0225
CAS:<p>CAA0225 is a selective inhibitor of cathepsin L. CAA0225 is a probe for autophagic proteolysis.</p>Formula:C28H29N3O5Color and Shape:SolidMolecular weight:487.55ITX-4520
CAS:<p>ITX-4520 novel highly potent, orally bioavailable inhibitor of hepatitis C virus (HCV) entry.</p>Formula:C24H23F2N3OSColor and Shape:SolidMolecular weight:439.52WAY-151693
CAS:<p>WAY-151693 is an inhibitor of human collagenase-3 (MMP-13).</p>Formula:C21H22ClN3O5SColor and Shape:SolidMolecular weight:463.93L 722151
CAS:<p>L 722151 is an FXIIIa inhibitor.</p>Formula:C8H9ClN2O5S3Purity:98%Color and Shape:SolidMolecular weight:344.82Epostatin
CAS:<p>Epostatin is a new dipeptidyl peptidase II (DPP-II, EC 3.4.14.2) inhibitor.</p>Formula:C23H33N3O5Purity:98%Color and Shape:SolidMolecular weight:431.53Chymase-IN-1
CAS:<p>Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).</p>Formula:C20H15ClNO4PSPurity:99.17%Color and Shape:SolidMolecular weight:431.83AL-9
CAS:<p>AL-9 is a GT-1b and GT-2a replication inhibitor.</p>Formula:C23H22N4O3Purity:98%Color and Shape:SolidMolecular weight:402.45ADAMTS-5-IN-2
CAS:<p>ADAMTS-5-IN-2 is a potent inhibitor of ADAMTS-5, exhibiting an IC50 of 0.71 µM, and holds potential for osteoarthritis research.</p>Formula:C17H15N3OSColor and Shape:SolidMolecular weight:309.39GSK-2793660
CAS:<p>GSK-2793660, an oral, irreversible CTSC inhibitor, aids bronchiectasis research.</p>Formula:C20H27N3O3Purity:98%Color and Shape:SolidMolecular weight:357.45Safironil
CAS:<p>Safironil, a novel antifibrotic, competitively inhibits collagen synthesis and modulates fibrosis, impacting type I/III collagen levels.</p>Formula:C15H23N3O4Purity:99.83%Color and Shape:SolidMolecular weight:309.36RID-F
CAS:<p>RID-F is an inhibitor of the nonpeptidic proteasome.</p>Formula:C38H50N2O2Purity:98%Color and Shape:SolidMolecular weight:566.82SP-Chymostatin B
CAS:<p>SP-Chymostatin B inhibits proteases like chymotrypsin and papain; less effective on human elastase; works at 100-200 μg/ml.</p>Formula:C30H41N7O6Purity:98%Color and Shape:SolidMolecular weight:595.69TNK2-IN-1
CAS:<p>TNK2-IN-1 is a TNK2 inhibitor (IC50: 224 nM) that can be used in cancer research.</p>Formula:C23H24N6O2Color and Shape:SolidMolecular weight:416.48BC-05
CAS:<p>BC-05, an orally active inhibitor targeting CD13 and the proteasome, displays potent inhibition with IC50 values of 0.13 μM against human CD13 and 1.39 μM for</p>Formula:C21H29BN2O9Purity:98%Color and Shape:SolidMolecular weight:464.27A-933548
CAS:<p>A-933548: potent calpain inhibitor, selective vs. cathepsins, stable, effective in cell assays.</p>Formula:C25H21N5O3Purity:98%Color and Shape:SolidMolecular weight:439.47Antiviral agent 30
CAS:<p>Antiviral Agent 30 (Example 118) is an active compound against HCV and RSV with an inhibitory concentration (IC 50) of greater than 25μM [1].</p>Formula:C21H32N2O3SColor and Shape:SolidMolecular weight:392.56K 579
CAS:<p>K 579 is a dipeptidyl peptidase IV inhibitor.</p>Formula:C17H24N6OPurity:98%Color and Shape:SolidMolecular weight:328.41Tyrosinase-IN-7
CAS:<p>Tyrosinase-IN-7 is a small-molecule tyrosinase inhibitor (IC50 1.57 μM) that suppresses melanin activity and cell growth with low cytotoxicity.</p>Formula:C15H10O5Purity:99%Color and Shape:SolidMolecular weight:270.24PTIQ
CAS:<p>MMP-3 expression inhibitor</p>Formula:C13H17NO3Purity:98%Color and Shape:SolidMolecular weight:235.28MDL 27399
CAS:<p>MDL 27399 suppresses human neutrophil cathepsin G.</p>Formula:C26H36N4O8Color and Shape:SolidMolecular weight:532.59AM 4299 B
CAS:<p>AM 4299 B is a novel inhibitor of a thiol protease.</p>Formula:C16H27N3O7Purity:98%Color and Shape:SolidMolecular weight:373.4BAY-678 racemate
CAS:<p>BAY-678 racemate: orally active, selective cell-permeable HNE inhibitor with IC50 of 20 nM.</p>Formula:C20H15F3N4O2Purity:98%Color and Shape:SolidMolecular weight:400.35HCV-IN-34
CAS:<p>HCV-IN-35, an oral HCV blocker, has an EC50 of 0.010 μM and a CC50 of 7.5 μM, indicating strong antiviral effects.</p>Formula:C31H36ClN5Color and Shape:SolidMolecular weight:514.1ABT-770
CAS:<p>ABT-770: an orally potent and selective MMP inhibitor, shown to reduce tumor growth in animal models.</p>Formula:C22H22F3N3O6Color and Shape:SolidMolecular weight:481.42Calpain Inhibitor XI
CAS:<p>Calpain Inhibitor XI, a reversible covalent inhibitor of calpain-1, is utilized in the research of neurodegenerative disorders.</p>Formula:C26H40N4O6Color and Shape:SolidMolecular weight:504.62Azo-Resveratrol
CAS:<p>Azo-Resveratrol is an analog of Resveratrol used as a potent tyrosinase inhibitor.</p>Formula:C12H10N2O3Color and Shape:SolidMolecular weight:230.22
