
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
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WNK-IN-7
CAS:<p>WNK-IN-7 is a potent and selective WNK1 kinase inhibitor.</p>Formula:C26H29N3OPurity:98%Color and Shape:SolidMolecular weight:399.53CA 074
CAS:<p>CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates</p>Formula:C18H29N3O6Purity:97.80%Color and Shape:SolidMolecular weight:383.44XMU-MP-2
CAS:<p>XMU-MP-2 is a potent and selective protease inhibitor with anticancer activity that inhibits the growth of oncogenic BRK-driven tumors in a mouse xenograft</p>Formula:C32H33F3N8O2Purity:99.29%Color and Shape:SolidMolecular weight:618.65BR351 precursor
CAS:<p>BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).</p>Formula:C27H32N2O8S2Purity:98%Color and Shape:SolidMolecular weight:576.68RS-104966
CAS:<p>RS-104966 is an inhibitor of collagenase that acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1.</p>Formula:C19H21NO6SPurity:98%Color and Shape:SolidMolecular weight:391.44(3S,4S)-A2-32-01
<p>(3S,4S)-A2-32-01, a less active (S,S)-enantiomer of A2-32-01. A2-32-01 is a potent caseinolytic protein proteases (ClpP) inhibitor .</p>Formula:C19H27NO2Color and Shape:SolidMolecular weight:301.42Ono-3307 mesylate
CAS:<p>no-3307 mesylate is a protease inhibitor that inhibits a variety of proteases and may be used to study pancreatitis.</p>Formula:C15H18N4O7S2Purity:97.60% - 98.16%Color and Shape:SolidMolecular weight:430.462',5-Difluoro-2'-deoxycytidine
CAS:<p>2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.</p>Formula:C9H11F2N3O4Purity:98%Color and Shape:SolidMolecular weight:263.2MMP-1-IN-1
<p>MMP-1-IN-1 is a highly potent MMP-1 inhibitor with an IC 50 of 0.034 μM .</p>Formula:C14H17ClN2O3Color and Shape:SolidMolecular weight:296.75Gü1303
CAS:<p>Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK).</p>Formula:C20H22N4O3Color and Shape:SolidMolecular weight:366.41HCV-IN-35
CAS:<p>HCV-IN-35 is a potent inhibitor of HCV and shows potential for infectious disease research.</p>Formula:C30H36ClN5Color and Shape:SolidMolecular weight:502.09Thrombin inhibitor 6
CAS:<p>Thrombin Inhibitor 6, with an IC 50 of 1 nM, acts as a potent anticoagulant by inhibiting thrombin.</p>Formula:C18H19ClN4O2SColor and Shape:SolidMolecular weight:390.89NAAA-IN-2
CAS:<p>NAAA-IN-2, a selective inhibitor with 50 nM IC50, targets NAAA, an enzyme hydrolyzing PEA/OEA, and may aid inflammation and pain studies.</p>Formula:C11H13N3O2SColor and Shape:SolidMolecular weight:251.3TAPI-0
CAS:<p>TAPI-0 is a matrix metalloprotease (MMP) and TACE inhibitor.</p>Formula:C24H32N4O5Color and Shape:SolidMolecular weight:456.53Tyrosinase-IN-10
CAS:<p>Tyrosinase-IN-10 serves as a partially competitive inhibitor of tyrosinase, demonstrating an inhibition concentration (IC50) value of 1.6 μM against the enzyme'</p>Formula:C16H12O4Color and Shape:SolidMolecular weight:268.26Calpain-2-IN-1
CAS:<p>Calpain-2-IN-1 is a selective calpain-2 inhibitor that prolongs ERK activation and thus enhances learning and memory.</p>Formula:C28H37N3O7Color and Shape:SolidMolecular weight:527.61LY 135305
CAS:<p>LY 135305 is a inhibition of spontaneous metastasis.</p>Formula:C19H20ClNPurity:98%Color and Shape:SolidMolecular weight:297.822-MPPA
CAS:<p>2-MPPA (GPI-5693) is a GCP II inhibitor and NAALADase inhibitor, used in research on neurodegenerative diseases.</p>Formula:C8H14O4SPurity:99.81%Color and Shape:SolidMolecular weight:206.26Plasma kallikrein-IN-3
CAS:<p>Plasma kallikrein-IN-3 is a potent inhibitor (IC50: 0.15 μM) used in hereditary angioedema and diabetic eye disease research.</p>Formula:C20H23N5O2Color and Shape:SolidMolecular weight:365.43Tec-IN-21
CAS:<p>Tec-IN-21 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2).</p>Formula:C16H15ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:362.83RO-9187
CAS:<p>RO-9187 is an effective HCV virus replication inhibitor(IC50: 171 nM).</p>Formula:C9H12N6O5Purity:98%Color and Shape:SolidMolecular weight:284.23Flovagatran
CAS:<p>Flovagatran (TGN 255) is a potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism.</p>Formula:C27H36BN3O7Purity:99.56%Color and Shape:SolidMolecular weight:525.4HCV-IN-3
CAS:<p>HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor (IC50: 20 μM; Kd: 29 μM).</p>Formula:C13H11F2NOPurity:98%Color and Shape:SolidMolecular weight:235.23Batimastat sodium salt
CAS:<p>Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).</p>Formula:C23H31N3NaO4S2Purity:98%Color and Shape:SolidMolecular weight:500.63BrBzGCp2
CAS:<p>BrBzGCp2 (p BrBzGSH(Cp)2) is a GLO1 inhibitor with antitumor activities, relieving anxiety, and is useful in researching neurological disorders.</p>Formula:C27H38BrN3O6SPurity:98.68% - 98.68%Color and Shape:SolidMolecular weight:612.58ACH-806
CAS:<p>ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.</p>Formula:C19H20F3N3O2SPurity:98%Color and Shape:SolidMolecular weight:411.44Sheng Gelieting
CAS:<p>CGT-8012 inhibits DP-IV enzyme, aiding type II diabetes research, with an IC50 of 87 nM.</p>Formula:C17H16F6N4OColor and Shape:SolidMolecular weight:406.33HCV-IN-37
CAS:<p>HCV-IN-37: potent HCV inhibitor, stable in rat plasma post-oral dose (15 mg/kg), blocks virus entry phase.</p>Formula:C31H35F2N5Color and Shape:SolidMolecular weight:515.64Tyrosinase-IN-1
CAS:<p>Tyrosinase-IN-1: potent inhibitor for skin-whitening & food preservation with uses in cosmetics & medicine.</p>Formula:C10H9N3O2S2Color and Shape:SolidMolecular weight:267.33Calpain Inhibitor XII
CAS:<p>Calpain Inhibitor XII (Z-L-Nva-CONH-CH2-2-Py) is a calpain I inhibitor that inhibits calpain II and cathepsin B.</p>Formula:C26H34N4O5Color and Shape:SolidMolecular weight:482.57Diprotin B
CAS:<p>Diprotin B is a dipeptidyl peptidase IV inhibitor.</p>Formula:C16H29N3O4Purity:98%Color and Shape:White Lyophilized PowderMolecular weight:327.42ZM223 hydrochloride (2031177-48-5 free base)
<p>ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.</p>Formula:C23H18ClF3N4O2S2Purity:98%Color and Shape:SolidMolecular weight:538.99MK-2048
CAS:<p>MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.</p>Formula:C21H21ClFN5O4Purity:98%Color and Shape:SolidMolecular weight:461.87Navuridine
CAS:<p>Navuridine (AZdU) is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.</p>Formula:C9H11N5O4Purity:99.83%Color and Shape:SolidMolecular weight:253.22KIN1400
CAS:<p>KIN1400 activates IRF3, boosts antiviral immunity, stimulates IFNbeta, and inhibits WNV, DV, and HCV.</p>Formula:C24H17F2N3O2SPurity:98%Color and Shape:SolidMolecular weight:449.47Cathepsin L/S-IN-1
<p>Cathepsin L/S-IN-1 inhibits Cathepsin L & S (IC50: 4.10 & 1.79 μM) and reduces metastasis in pancreatic cancer cells.</p>Formula:C29H33BrN4O4SColor and Shape:SolidMolecular weight:613.57OM-189
CAS:<p>OM-189 is a selective inhibitor of synthetic thrombin.</p>Formula:C24H36N6O3SPurity:98%Color and Shape:SolidMolecular weight:488.65NNGH
CAS:<p>NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane-binding.</p>Formula:C13H20N2O5SPurity:98.41%Color and Shape:SolidMolecular weight:316.37Cofrogliptin
CAS:<p>Cofrogliptin (HSK7653) is a DPP-4 inhibitor with hypoglycemic effects, which can be used to study type 2 diabetes (T2D).</p>Formula:C18H19F5N4O3SColor and Shape:SolidMolecular weight:466.43Ro 09-1679
CAS:<p>Ro 09-1679 is a thrombin inhibitor.</p>Formula:C22H39N9O6Purity:98%Color and Shape:SolidMolecular weight:525.6Gü2602
CAS:<p>Gü2602 inhibits the cathepsin K zymogen autocatalytic activation that is a potent, reversible inhibitor of cathepsin K (CatK) with a Ki of 0.013 nM for mature</p>Formula:C16H22N4O3Color and Shape:SolidMolecular weight:318.37Adafosbuvir PM
CAS:<p>Adafosbuvir PM (AL-335 PM) is a small molecule NS5B inhibitor that can be used to study chronic hepatitis C.</p>Formula:C10H13FN2O6Purity:97.08%Color and Shape:SolidMolecular weight:276.22BC-23
CAS:<p>BC-23 (NSC 45382) is a proteasome inhibitor with antitumor and antimicrobial activity for the study of leukemia and small cell lung cancer.</p>Formula:C21H14ClN3O4SPurity:98%Color and Shape:SolidMolecular weight:439.87CP-471474
CAS:<p>MMP inhibitor with IC50: MMP-2 (0.7 nM), MMP-13 (0.9 nM), MMP-9 (13 nM), MMP-3 (16 nM), MMP-1 (1170 nM); reduces heart dilation post-infarct.</p>Formula:C16H17FN2O5SPurity:98%Color and Shape:SolidMolecular weight:368.38PF-00356231 hydrochloride
CAS:<p>PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM.</p>Formula:C25H21ClN2O3SPurity:98.39%Color and Shape:SolidMolecular weight:464.96Tyrosinase-IN-3
CAS:<p>Tyrosinase-IN-3 inhibits melanin production; potential for skin whitening and food preservation.</p>Formula:C21H23NO5Color and Shape:SolidMolecular weight:369.41AGLME
CAS:<p>AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.</p>Formula:C11H21N3O4Color and Shape:SolidMolecular weight:259.3p-Aminobenzamidine dihydrochloride
CAS:<p>4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type</p>Formula:C7H11Cl2N3Purity:99.00% - 99.56%Color and Shape:SolidMolecular weight:208.088FK-448 Free base
CAS:<p>FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM.</p>Formula:C25H30N2O3Purity:98%Color and Shape:SolidMolecular weight:406.52N-Phenylthiourea
CAS:<p>N-Phenylthiourea (Phenylthiocarbamide) is EC 1.14.18.1 (tyrosinase) inhibitor, a diphenolase inhibitor, and a non-competitive inhibitor of the PvdP tyrosinase.</p>Formula:C7H8N2SPurity:99.71%Color and Shape:SolidMolecular weight:152.22
