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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • WNK-IN-7

    CAS:
    <p>WNK-IN-7 is a potent and selective WNK1 kinase inhibitor.</p>
    Formula:C26H29N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:399.53
  • CA 074

    CAS:
    <p>CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates</p>
    Formula:C18H29N3O6
    Purity:97.80%
    Color and Shape:Solid
    Molecular weight:383.44
  • XMU-MP-2

    CAS:
    <p>XMU-MP-2 is a potent and selective protease inhibitor with anticancer activity that inhibits the growth of oncogenic BRK-driven tumors in a mouse xenograft</p>
    Formula:C32H33F3N8O2
    Purity:99.29%
    Color and Shape:Solid
    Molecular weight:618.65
  • BR351 precursor

    CAS:
    <p>BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).</p>
    Formula:C27H32N2O8S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:576.68
  • RS-104966

    CAS:
    <p>RS-104966 is an inhibitor of collagenase that acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1.</p>
    Formula:C19H21NO6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:391.44
  • (3S,4S)-A2-32-01


    <p>(3S,4S)-A2-32-01, a less active (S,S)-enantiomer of A2-32-01. A2-32-01 is a potent caseinolytic protein proteases (ClpP) inhibitor .</p>
    Formula:C19H27NO2
    Color and Shape:Solid
    Molecular weight:301.42
  • Ono-3307 mesylate

    CAS:
    <p>no-3307 mesylate is a protease inhibitor that inhibits a variety of proteases and may be used to study pancreatitis.</p>
    Formula:C15H18N4O7S2
    Purity:97.60% - 98.16%
    Color and Shape:Solid
    Molecular weight:430.46
  • 2',5-Difluoro-2'-deoxycytidine

    CAS:
    <p>2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.</p>
    Formula:C9H11F2N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:263.2
  • MMP-1-IN-1


    <p>MMP-1-IN-1 is a highly potent MMP-1 inhibitor with an IC 50 of 0.034 μM .</p>
    Formula:C14H17ClN2O3
    Color and Shape:Solid
    Molecular weight:296.75
  • Gü1303

    CAS:
    <p>Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK).</p>
    Formula:C20H22N4O3
    Color and Shape:Solid
    Molecular weight:366.41
  • HCV-IN-35

    CAS:
    <p>HCV-IN-35 is a potent inhibitor of HCV and shows potential for infectious disease research.</p>
    Formula:C30H36ClN5
    Color and Shape:Solid
    Molecular weight:502.09
  • Thrombin inhibitor 6

    CAS:
    <p>Thrombin Inhibitor 6, with an IC 50 of 1 nM, acts as a potent anticoagulant by inhibiting thrombin.</p>
    Formula:C18H19ClN4O2S
    Color and Shape:Solid
    Molecular weight:390.89
  • NAAA-IN-2

    CAS:
    <p>NAAA-IN-2, a selective inhibitor with 50 nM IC50, targets NAAA, an enzyme hydrolyzing PEA/OEA, and may aid inflammation and pain studies.</p>
    Formula:C11H13N3O2S
    Color and Shape:Solid
    Molecular weight:251.3
  • TAPI-0

    CAS:
    <p>TAPI-0 is a matrix metalloprotease (MMP) and TACE inhibitor.</p>
    Formula:C24H32N4O5
    Color and Shape:Solid
    Molecular weight:456.53
  • Tyrosinase-IN-10

    CAS:
    <p>Tyrosinase-IN-10 serves as a partially competitive inhibitor of tyrosinase, demonstrating an inhibition concentration (IC50) value of 1.6 μM against the enzyme'</p>
    Formula:C16H12O4
    Color and Shape:Solid
    Molecular weight:268.26
  • Calpain-2-IN-1

    CAS:
    <p>Calpain-2-IN-1 is a selective calpain-2 inhibitor that prolongs ERK activation and thus enhances learning and memory.</p>
    Formula:C28H37N3O7
    Color and Shape:Solid
    Molecular weight:527.61
  • LY 135305

    CAS:
    <p>LY 135305 is a inhibition of spontaneous metastasis.</p>
    Formula:C19H20ClN
    Purity:98%
    Color and Shape:Solid
    Molecular weight:297.82
  • 2-MPPA

    CAS:
    <p>2-MPPA (GPI-5693) is a GCP II inhibitor and NAALADase inhibitor, used in research on neurodegenerative diseases.</p>
    Formula:C8H14O4S
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:206.26
  • Plasma kallikrein-IN-3

    CAS:
    <p>Plasma kallikrein-IN-3 is a potent inhibitor (IC50: 0.15 μM) used in hereditary angioedema and diabetic eye disease research.</p>
    Formula:C20H23N5O2
    Color and Shape:Solid
    Molecular weight:365.43
  • Tec-IN-21

    CAS:
    <p>Tec-IN-21 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2).</p>
    Formula:C16H15ClN4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:362.83
  • RO-9187

    CAS:
    <p>RO-9187 is an effective HCV virus replication inhibitor(IC50: 171 nM).</p>
    Formula:C9H12N6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:284.23
  • Flovagatran

    CAS:
    <p>Flovagatran (TGN 255) is a potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism.</p>
    Formula:C27H36BN3O7
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:525.4
  • HCV-IN-3

    CAS:
    <p>HCV-IN-3 is a hepatitis C virus (HCV) NS3/4a protein inhibitor (IC50: 20 μM; Kd: 29 μM).</p>
    Formula:C13H11F2NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:235.23
  • Batimastat sodium salt

    CAS:
    <p>Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).</p>
    Formula:C23H31N3NaO4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:500.63
  • BrBzGCp2

    CAS:
    <p>BrBzGCp2 (p BrBzGSH(Cp)2) is a GLO1 inhibitor with antitumor activities, relieving anxiety, and is useful in researching neurological disorders.</p>
    Formula:C27H38BrN3O6S
    Purity:98.68% - 98.68%
    Color and Shape:Solid
    Molecular weight:612.58
  • ACH-806

    CAS:
    <p>ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.</p>
    Formula:C19H20F3N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:411.44
  • Sheng Gelieting

    CAS:
    <p>CGT-8012 inhibits DP-IV enzyme, aiding type II diabetes research, with an IC50 of 87 nM.</p>
    Formula:C17H16F6N4O
    Color and Shape:Solid
    Molecular weight:406.33
  • HCV-IN-37

    CAS:
    <p>HCV-IN-37: potent HCV inhibitor, stable in rat plasma post-oral dose (15 mg/kg), blocks virus entry phase.</p>
    Formula:C31H35F2N5
    Color and Shape:Solid
    Molecular weight:515.64
  • Tyrosinase-IN-1

    CAS:
    <p>Tyrosinase-IN-1: potent inhibitor for skin-whitening &amp; food preservation with uses in cosmetics &amp; medicine.</p>
    Formula:C10H9N3O2S2
    Color and Shape:Solid
    Molecular weight:267.33
  • Calpain Inhibitor XII

    CAS:
    <p>Calpain Inhibitor XII (Z-L-Nva-CONH-CH2-2-Py) is a calpain I inhibitor that inhibits calpain II and cathepsin B.</p>
    Formula:C26H34N4O5
    Color and Shape:Solid
    Molecular weight:482.57
  • Diprotin B

    CAS:
    <p>Diprotin B is a dipeptidyl peptidase IV inhibitor.</p>
    Formula:C16H29N3O4
    Purity:98%
    Color and Shape:White Lyophilized Powder
    Molecular weight:327.42
  • ZM223 hydrochloride (2031177-48-5 free base)


    <p>ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.</p>
    Formula:C23H18ClF3N4O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:538.99
  • MK-2048

    CAS:
    <p>MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.</p>
    Formula:C21H21ClFN5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:461.87
  • Navuridine

    CAS:
    <p>Navuridine (AZdU) is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.</p>
    Formula:C9H11N5O4
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:253.22
  • KIN1400

    CAS:
    <p>KIN1400 activates IRF3, boosts antiviral immunity, stimulates IFNbeta, and inhibits WNV, DV, and HCV.</p>
    Formula:C24H17F2N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:449.47
  • Cathepsin L/S-IN-1


    <p>Cathepsin L/S-IN-1 inhibits Cathepsin L &amp; S (IC50: 4.10 &amp; 1.79 μM) and reduces metastasis in pancreatic cancer cells.</p>
    Formula:C29H33BrN4O4S
    Color and Shape:Solid
    Molecular weight:613.57
  • OM-189

    CAS:
    <p>OM-189 is a selective inhibitor of synthetic thrombin.</p>
    Formula:C24H36N6O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:488.65
  • NNGH

    CAS:
    <p>NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane-binding.</p>
    Formula:C13H20N2O5S
    Purity:98.41%
    Color and Shape:Solid
    Molecular weight:316.37
  • Cofrogliptin

    CAS:
    <p>Cofrogliptin (HSK7653) is a DPP-4 inhibitor with hypoglycemic effects, which can be used to study type 2 diabetes (T2D).</p>
    Formula:C18H19F5N4O3S
    Color and Shape:Solid
    Molecular weight:466.43
  • Ro 09-1679

    CAS:
    <p>Ro 09-1679 is a thrombin inhibitor.</p>
    Formula:C22H39N9O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:525.6
  • Gü2602

    CAS:
    <p>Gü2602 inhibits the cathepsin K zymogen autocatalytic activation that is a potent, reversible inhibitor of cathepsin K (CatK) with a Ki of 0.013 nM for mature</p>
    Formula:C16H22N4O3
    Color and Shape:Solid
    Molecular weight:318.37
  • Adafosbuvir PM

    CAS:
    <p>Adafosbuvir PM (AL-335 PM) is a small molecule NS5B inhibitor that can be used to study chronic hepatitis C.</p>
    Formula:C10H13FN2O6
    Purity:97.08%
    Color and Shape:Solid
    Molecular weight:276.22
  • BC-23

    CAS:
    <p>BC-23 (NSC 45382) is a proteasome inhibitor with antitumor and antimicrobial activity for the study of leukemia and small cell lung cancer.</p>
    Formula:C21H14ClN3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:439.87
  • CP-471474

    CAS:
    <p>MMP inhibitor with IC50: MMP-2 (0.7 nM), MMP-13 (0.9 nM), MMP-9 (13 nM), MMP-3 (16 nM), MMP-1 (1170 nM); reduces heart dilation post-infarct.</p>
    Formula:C16H17FN2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:368.38
  • PF-00356231 hydrochloride

    CAS:
    <p>PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM.</p>
    Formula:C25H21ClN2O3S
    Purity:98.39%
    Color and Shape:Solid
    Molecular weight:464.96
  • Tyrosinase-IN-3

    CAS:
    <p>Tyrosinase-IN-3 inhibits melanin production; potential for skin whitening and food preservation.</p>
    Formula:C21H23NO5
    Color and Shape:Solid
    Molecular weight:369.41
  • AGLME

    CAS:
    <p>AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.</p>
    Formula:C11H21N3O4
    Color and Shape:Solid
    Molecular weight:259.3
  • p-Aminobenzamidine dihydrochloride

    CAS:
    <p>4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type</p>
    Formula:C7H11Cl2N3
    Purity:99.00% - 99.56%
    Color and Shape:Solid
    Molecular weight:208.088
  • FK-448 Free base

    CAS:
    <p>FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM.</p>
    Formula:C25H30N2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:406.52
  • N-Phenylthiourea

    CAS:
    <p>N-Phenylthiourea (Phenylthiocarbamide) is EC 1.14.18.1 (tyrosinase) inhibitor, a diphenolase inhibitor, and a non-competitive inhibitor of the PvdP tyrosinase.</p>
    Formula:C7H8N2S
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:152.22