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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 1045 products of "Proteases/Proteasome"

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  • Lenacapavir

    CAS:
    <p>Lenacapavir (GS-6207) is the first HIV-1 capsid inhibitor approved by the U.S. Food and Drug Administration, the European Medicines Agency, and Health Canada for the treatment of MDR HIV-1 infection.Cost-effective and quality-assured.</p>
    Formula:C39H32ClF10N7O5S2
    Purity:99.61% - 99.87%
    Color and Shape:Solid
    Molecular weight:968.28
  • Etarotene

    CAS:
    <p>Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a</p>
    Formula:C25H32O2S
    Purity:99.58% - 99.93%
    Color and Shape:Solid
    Molecular weight:396.59
  • BDCRB


    <p>BDCRB disrupts HCMV DNA maturation by altering terminase cleavage, extending packaging 30 kb until second site.</p>
    Formula:C12H11BrCl2N2O4
    Purity:99.41% - 99.43%
    Color and Shape:Soild
    Molecular weight:398.04
  • BILB-1941

    CAS:
    <p>BILB-1941 (BILB-1941ZW) is an inhibitor of HCV NS5B polymerase and can be used in studies about HCV infection.</p>
    Formula:C34H34N4O4
    Purity:99.51% - 99.65%
    Color and Shape:Solid
    Molecular weight:562.66
  • 2'-C-Methyladenosine

    CAS:
    <p>2'-C-Methyladenosine from C. renalis inhibits HCV, NS5B RNA synthesis (IC50: 0.3, 1.9µM), and LRV1 in L. guyanensis, L. braziliensis.</p>
    Formula:C11H15N5O4
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:281.27
  • CPA inhibitor

    CAS:
    <p>CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.</p>
    Formula:C18H19NO4
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:313.35
  • Cathepsin X-IN-1

    CAS:
    <p>Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].</p>
    Formula:C15H13N3O3S
    Purity:99.34%
    Color and Shape:Solid
    Molecular weight:315.35
  • P32/98 hemifumarate

    CAS:
    <p>P32/98 hemifumarate is a DPP4 inhibitor with hypoglycemic properties and is used in the study of type 2 diabetes.</p>
    Formula:C22H40N4O6S2
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:520.71
  • Atevirdine

    CAS:
    <p>Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).</p>
    Formula:C21H25N5O2
    Purity:98.20%
    Color and Shape:Solid
    Molecular weight:379.46
  • DB04760

    CAS:
    <p>DB04760: selective MMP-13 inhibitor, non-zinc-chelating, IC50=8nM, reduces paclitaxel neurotoxicity, anticancer.</p>
    Formula:C22H20F2N4O2
    Purity:99.93% - 99.99%
    Color and Shape:Solid
    Molecular weight:410.42
  • JNJ-10311795

    CAS:
    <p>JNJ-10311795 (RWJ-355871) is an inhibitor of neutrophil elastase G and mast cell chymase, demonstrating significant anti-inflammatory effects.</p>
    Formula:C40H35N2O6P
    Purity:97.43%
    Color and Shape:Solid
    Molecular weight:670.69
  • TG-2-IN-1

    CAS:
    <p>TG-2-IN-1 (Compound D003) is a transglutaminase-2 ( TGM-2 ) inhibitor. TG-2-IN-1 can be used in myopia research[1].</p>
    Formula:C8H13ClN2OS
    Purity:98.43%
    Color and Shape:Solid
    Molecular weight:220.72
  • CP-544439

    CAS:
    <p>CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development.</p>
    Formula:C18H19FN2O6S
    Purity:95.02% - 98.66%
    Color and Shape:Solid
    Molecular weight:410.42
  • Setrobuvir

    CAS:
    <p>Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with</p>
    Formula:C25H25FN4O6S2
    Purity:98.92% - >99.99%
    Color and Shape:Solid
    Molecular weight:560.62
  • Granotapide

    CAS:
    <p>Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic</p>
    Formula:C39H37F3N2O8
    Purity:99.70% - 99.79%
    Color and Shape:Solid
    Molecular weight:718.71
  • PG-116800

    CAS:
    <p>PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.</p>
    Formula:C24H27N3O7S
    Purity:98.03% - 99.66%
    Color and Shape:Solid
    Molecular weight:501.55
  • Sovaprevir

    CAS:
    <p>Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.</p>
    Formula:C43H53N5O8S
    Purity:99.11%
    Color and Shape:Solid
    Molecular weight:799.97
  • Melagatran

    CAS:
    <p>Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin.Cost-effective and quality-assured.</p>
    Formula:C22H31N5O4
    Purity:98.29% - >99.99%
    Color and Shape:Solid
    Molecular weight:429.51
  • Opaviraline

    CAS:
    <p>Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.</p>
    Formula:C14H17FN2O3
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:280.29
  • MMP2-IN-3

    CAS:
    <p>MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM).</p>
    Formula:C23H21N3O
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:355.43
  • Uprifosbuvir

    CAS:
    <p>Uprifosbuvir is an inhibitor of uridine nucleotide analog HCV NS5B polymerase.</p>
    Formula:C22H29ClN3O9P
    Purity:99.73% - >99.99%
    Color and Shape:Solid
    Molecular weight:545.91
  • Sirpiglenastat

    CAS:
    <p>Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.</p>
    Formula:C22H27N5O5
    Purity:98.01% - 98.37%
    Color and Shape:Solid
    Molecular weight:441.48
  • Emivirine

    CAS:
    <p>Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.</p>
    Formula:C17H22N2O3
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:302.37
  • Tyrosinase-IN-2

    CAS:
    <p>Tyrosinase-IN-2, a potent tyrosinase inhibitor, may help in skin lightening and food preservation research.</p>
    Formula:C8H8N4O2S
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:224.24
  • Isatoribine

    CAS:
    <p>Isatoribine(ANA245) free base is a potent TLR7 receptor agonist with anti-hepatitis C virus infection activity for the study of HCV infection.</p>
    Formula:C10H12N4O6S
    Purity:98.99% - 99.75%
    Color and Shape:Solid
    Molecular weight:316.29
  • AGPS-IN-2i

    CAS:
    <p>AGPS-IN-2i inhibits alkylglycerol phosphate synthase, affecting ether lipid metabolism and reducing cancer cell migration and proliferation.</p>
    Formula:C18H17F2N3O2
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:345.34
  • HIV-1 integrase inhibitor 8

    CAS:
    <p>HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].</p>
    Formula:C21H24O2
    Purity:98.91%
    Color and Shape:Solid
    Molecular weight:308.41
  • TS-021

    CAS:
    <p>TS-021 is a selective dipeptidyl peptidase 4 (DPP-4) inhibitor with antidiabetic activity for the study of type 2 diabetes.</p>
    Formula:C17H24FN3O5S
    Purity:>99.99% - >99.99%
    Color and Shape:Solid
    Molecular weight:401.45
  • MMP-2/MMP-9 Inhibitor I

    CAS:
    <p>MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.</p>
    Formula:C21H19NO4S
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:381.44
  • KM-023

    CAS:
    <p>KM-023 is a new second-generation non-nucleoside reverse transcriptase inhibitor for the study of human immunodeficiency virus (HIV) type 1 infection.</p>
    Formula:C18H19N3O3
    Purity:99.47% - >99.99%
    Color and Shape:Solid
    Molecular weight:325.36
  • L 756423

    CAS:
    <p>L756423 is a potent, selective HIV protease inhibitor (Ki=0.049 nM), effective against HIV spread in MT25 lymphocytes at 0.1-0.5 nM, useful for AIDS research.</p>
    Formula:C39H48N4O5
    Purity:99.34% - 99.88%
    Color and Shape:Solid
    Molecular weight:652.82
  • 20S Proteasome activator 1

    CAS:
    <p>20S Proteasome activator 1: IC50—0.3 μM (trypsin), 0.7 μM (chymotrypsin), 1.8 μM (caspase); reduces alpha-synuclein A53T, aids neurodegenerative studies.</p>
    Formula:C27H19ClF2N2OS
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:492.97
  • Gemigliptin

    CAS:
    <p>Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)</p>
    Formula:C18H19F8N5O2
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:489.36
  • MK-8325

    CAS:
    <p>MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailability</p>
    Formula:C43H54Cl2F2N8O6Si
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:915.93
  • Thrombin inhibitor 1

    CAS:
    <p>Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).</p>
    Formula:C22H20Cl2F2N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:497.32
  • GS-6620

    CAS:
    <p>GS-6620 is a HCV nonstructural protein 5B (NS5B) inhibitor.</p>
    Formula:C29H37N6O9P
    Color and Shape:Solid
    Molecular weight:644.61
  • SSR 69071

    CAS:
    <p>SSR69071: selective neutrophil elastase inhibitor, stronger for humans (Ki=0.0168 nM), may treat COPD, asthma, and reduce heart injury.</p>
    Formula:C27H32N4O7S
    Color and Shape:Solid
    Molecular weight:556.63
  • NS5A-IN-2

    CAS:
    <p>NS5A-IN-2, a potent inhibitor, is highly effective against HCV 1b and shows increased activity for GT 3a with good metabolic stability.</p>
    Formula:C46H45N7O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:807.89
  • XL-784

    CAS:
    <p>XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.</p>
    Formula:C42H42Cl2F4MgN6O16S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1122.15
  • Ravidasvir HCl

    CAS:
    <p>Ravidasvir, also known as PPI-668 and ASC16, is a second-generation, orally active, potent and selective HCV NS5A protein inhibitor.</p>
    Formula:C42H52Cl2N8O6
    Color and Shape:Solid
    Molecular weight:835.828
  • Inogatran

    CAS:
    <p>Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.</p>
    Formula:C21H38N6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.56
  • Paltimatrectinib

    CAS:
    <p>Paltimatrectinib (PBI-200) is a tyrosine kinase inhibitor with anticancer activity, and is used in the study of bladder, breast, and colorectal cancers.</p>
    Formula:C20H15F5N6
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:434.37
  • ABP 25

    CAS:
    <p>ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.</p>
    Formula:C55H66ClN5O3
    Color and Shape:Solid
    Molecular weight:880.6
  • Beclabuvir HCl

    CAS:
    <p>Beclabuvir (BMS-791325) is an HCV inhibitor targeting NS5B polymerase with sub-28 nM potency for genotypes 1, 3, 4, 5.</p>
    Formula:C36H46ClN5O5S
    Color and Shape:Solid
    Molecular weight:696.3
  • BAY-678

    CAS:
    <p>BAY-678: Oral selective human neutrophil elastase inhibitor; IC50: 20 nM; SGC-approved chemical probe.</p>
    Formula:C20H15F3N4O2
    Purity:97.89%
    Color and Shape:Solid
    Molecular weight:400.35
  • Proteasome-IN-5

    CAS:
    <p>Proteasome-IN-5, also known as compound 5, acts as a proteasome inhibitor [1].</p>
    Formula:C20H30BN5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:463.29
  • Collagen proline hydroxylase inhibitor

    CAS:
    <p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>
    Formula:C18H18N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:354.36
  • Ro 31-9790

    CAS:
    <p>Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).</p>
    Formula:C15H29N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:315.41
  • ONO 4817

    CAS:
    <p>ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.</p>
    Formula:C22H28N2O6
    Color and Shape:Solid
    Molecular weight:416.47
  • MMP-7-IN-3

    CAS:
    <p>MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.</p>
    Formula:C34H43ClF3N7O9S
    Purity:99.915%
    Color and Shape:Solid
    Molecular weight:818.26