
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
Show 3 more subcategories
Found 1045 products of "Proteases/Proteasome"
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Lenacapavir
CAS:<p>Lenacapavir (GS-6207) is the first HIV-1 capsid inhibitor approved by the U.S. Food and Drug Administration, the European Medicines Agency, and Health Canada for the treatment of MDR HIV-1 infection.Cost-effective and quality-assured.</p>Formula:C39H32ClF10N7O5S2Purity:99.61% - 99.87%Color and Shape:SolidMolecular weight:968.28Etarotene
CAS:<p>Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a</p>Formula:C25H32O2SPurity:99.58% - 99.93%Color and Shape:SolidMolecular weight:396.59BDCRB
<p>BDCRB disrupts HCMV DNA maturation by altering terminase cleavage, extending packaging 30 kb until second site.</p>Formula:C12H11BrCl2N2O4Purity:99.41% - 99.43%Color and Shape:SoildMolecular weight:398.04BILB-1941
CAS:<p>BILB-1941 (BILB-1941ZW) is an inhibitor of HCV NS5B polymerase and can be used in studies about HCV infection.</p>Formula:C34H34N4O4Purity:99.51% - 99.65%Color and Shape:SolidMolecular weight:562.662'-C-Methyladenosine
CAS:<p>2'-C-Methyladenosine from C. renalis inhibits HCV, NS5B RNA synthesis (IC50: 0.3, 1.9µM), and LRV1 in L. guyanensis, L. braziliensis.</p>Formula:C11H15N5O4Purity:99.85%Color and Shape:SolidMolecular weight:281.27CPA inhibitor
CAS:<p>CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.</p>Formula:C18H19NO4Purity:99.94%Color and Shape:SolidMolecular weight:313.35Cathepsin X-IN-1
CAS:<p>Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].</p>Formula:C15H13N3O3SPurity:99.34%Color and Shape:SolidMolecular weight:315.35P32/98 hemifumarate
CAS:<p>P32/98 hemifumarate is a DPP4 inhibitor with hypoglycemic properties and is used in the study of type 2 diabetes.</p>Formula:C22H40N4O6S2Purity:99.46%Color and Shape:SolidMolecular weight:520.71Atevirdine
CAS:<p>Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).</p>Formula:C21H25N5O2Purity:98.20%Color and Shape:SolidMolecular weight:379.46DB04760
CAS:<p>DB04760: selective MMP-13 inhibitor, non-zinc-chelating, IC50=8nM, reduces paclitaxel neurotoxicity, anticancer.</p>Formula:C22H20F2N4O2Purity:99.93% - 99.99%Color and Shape:SolidMolecular weight:410.42JNJ-10311795
CAS:<p>JNJ-10311795 (RWJ-355871) is an inhibitor of neutrophil elastase G and mast cell chymase, demonstrating significant anti-inflammatory effects.</p>Formula:C40H35N2O6PPurity:97.43%Color and Shape:SolidMolecular weight:670.69TG-2-IN-1
CAS:<p>TG-2-IN-1 (Compound D003) is a transglutaminase-2 ( TGM-2 ) inhibitor. TG-2-IN-1 can be used in myopia research[1].</p>Formula:C8H13ClN2OSPurity:98.43%Color and Shape:SolidMolecular weight:220.72CP-544439
CAS:<p>CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development.</p>Formula:C18H19FN2O6SPurity:95.02% - 98.66%Color and Shape:SolidMolecular weight:410.42Setrobuvir
CAS:<p>Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with</p>Formula:C25H25FN4O6S2Purity:98.92% - >99.99%Color and Shape:SolidMolecular weight:560.62Granotapide
CAS:<p>Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic</p>Formula:C39H37F3N2O8Purity:99.70% - 99.79%Color and Shape:SolidMolecular weight:718.71PG-116800
CAS:<p>PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.</p>Formula:C24H27N3O7SPurity:98.03% - 99.66%Color and Shape:SolidMolecular weight:501.55Sovaprevir
CAS:<p>Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.</p>Formula:C43H53N5O8SPurity:99.11%Color and Shape:SolidMolecular weight:799.97Melagatran
CAS:<p>Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin.Cost-effective and quality-assured.</p>Formula:C22H31N5O4Purity:98.29% - >99.99%Color and Shape:SolidMolecular weight:429.51Opaviraline
CAS:<p>Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.</p>Formula:C14H17FN2O3Purity:99.94%Color and Shape:SolidMolecular weight:280.29MMP2-IN-3
CAS:<p>MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM).</p>Formula:C23H21N3OPurity:99.38%Color and Shape:SolidMolecular weight:355.43Uprifosbuvir
CAS:<p>Uprifosbuvir is an inhibitor of uridine nucleotide analog HCV NS5B polymerase.</p>Formula:C22H29ClN3O9PPurity:99.73% - >99.99%Color and Shape:SolidMolecular weight:545.91Sirpiglenastat
CAS:<p>Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.</p>Formula:C22H27N5O5Purity:98.01% - 98.37%Color and Shape:SolidMolecular weight:441.48Emivirine
CAS:<p>Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.</p>Formula:C17H22N2O3Purity:99.8%Color and Shape:SolidMolecular weight:302.37Tyrosinase-IN-2
CAS:<p>Tyrosinase-IN-2, a potent tyrosinase inhibitor, may help in skin lightening and food preservation research.</p>Formula:C8H8N4O2SPurity:99.78%Color and Shape:SolidMolecular weight:224.24Isatoribine
CAS:<p>Isatoribine(ANA245) free base is a potent TLR7 receptor agonist with anti-hepatitis C virus infection activity for the study of HCV infection.</p>Formula:C10H12N4O6SPurity:98.99% - 99.75%Color and Shape:SolidMolecular weight:316.29AGPS-IN-2i
CAS:<p>AGPS-IN-2i inhibits alkylglycerol phosphate synthase, affecting ether lipid metabolism and reducing cancer cell migration and proliferation.</p>Formula:C18H17F2N3O2Purity:98.92%Color and Shape:SolidMolecular weight:345.34HIV-1 integrase inhibitor 8
CAS:<p>HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].</p>Formula:C21H24O2Purity:98.91%Color and Shape:SolidMolecular weight:308.41TS-021
CAS:<p>TS-021 is a selective dipeptidyl peptidase 4 (DPP-4) inhibitor with antidiabetic activity for the study of type 2 diabetes.</p>Formula:C17H24FN3O5SPurity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:401.45MMP-2/MMP-9 Inhibitor I
CAS:<p>MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.</p>Formula:C21H19NO4SPurity:99.74%Color and Shape:SolidMolecular weight:381.44KM-023
CAS:<p>KM-023 is a new second-generation non-nucleoside reverse transcriptase inhibitor for the study of human immunodeficiency virus (HIV) type 1 infection.</p>Formula:C18H19N3O3Purity:99.47% - >99.99%Color and Shape:SolidMolecular weight:325.36L 756423
CAS:<p>L756423 is a potent, selective HIV protease inhibitor (Ki=0.049 nM), effective against HIV spread in MT25 lymphocytes at 0.1-0.5 nM, useful for AIDS research.</p>Formula:C39H48N4O5Purity:99.34% - 99.88%Color and Shape:SolidMolecular weight:652.8220S Proteasome activator 1
CAS:<p>20S Proteasome activator 1: IC50—0.3 μM (trypsin), 0.7 μM (chymotrypsin), 1.8 μM (caspase); reduces alpha-synuclein A53T, aids neurodegenerative studies.</p>Formula:C27H19ClF2N2OSPurity:99.82%Color and Shape:SolidMolecular weight:492.97Gemigliptin
CAS:<p>Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)</p>Formula:C18H19F8N5O2Purity:99.72%Color and Shape:SolidMolecular weight:489.36MK-8325
CAS:<p>MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailability</p>Formula:C43H54Cl2F2N8O6SiPurity:>99.99%Color and Shape:SolidMolecular weight:915.93Thrombin inhibitor 1
CAS:<p>Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).</p>Formula:C22H20Cl2F2N4O3Purity:98%Color and Shape:SolidMolecular weight:497.32GS-6620
CAS:<p>GS-6620 is a HCV nonstructural protein 5B (NS5B) inhibitor.</p>Formula:C29H37N6O9PColor and Shape:SolidMolecular weight:644.61SSR 69071
CAS:<p>SSR69071: selective neutrophil elastase inhibitor, stronger for humans (Ki=0.0168 nM), may treat COPD, asthma, and reduce heart injury.</p>Formula:C27H32N4O7SColor and Shape:SolidMolecular weight:556.63NS5A-IN-2
CAS:<p>NS5A-IN-2, a potent inhibitor, is highly effective against HCV 1b and shows increased activity for GT 3a with good metabolic stability.</p>Formula:C46H45N7O7Purity:98%Color and Shape:SolidMolecular weight:807.89XL-784
CAS:<p>XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.</p>Formula:C42H42Cl2F4MgN6O16S2Purity:98%Color and Shape:SolidMolecular weight:1122.15Ravidasvir HCl
CAS:<p>Ravidasvir, also known as PPI-668 and ASC16, is a second-generation, orally active, potent and selective HCV NS5A protein inhibitor.</p>Formula:C42H52Cl2N8O6Color and Shape:SolidMolecular weight:835.828Inogatran
CAS:<p>Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.</p>Formula:C21H38N6O4Purity:98%Color and Shape:SolidMolecular weight:438.56Paltimatrectinib
CAS:<p>Paltimatrectinib (PBI-200) is a tyrosine kinase inhibitor with anticancer activity, and is used in the study of bladder, breast, and colorectal cancers.</p>Formula:C20H15F5N6Purity:99.96%Color and Shape:SolidMolecular weight:434.37ABP 25
CAS:<p>ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.</p>Formula:C55H66ClN5O3Color and Shape:SolidMolecular weight:880.6Beclabuvir HCl
CAS:<p>Beclabuvir (BMS-791325) is an HCV inhibitor targeting NS5B polymerase with sub-28 nM potency for genotypes 1, 3, 4, 5.</p>Formula:C36H46ClN5O5SColor and Shape:SolidMolecular weight:696.3BAY-678
CAS:<p>BAY-678: Oral selective human neutrophil elastase inhibitor; IC50: 20 nM; SGC-approved chemical probe.</p>Formula:C20H15F3N4O2Purity:97.89%Color and Shape:SolidMolecular weight:400.35Proteasome-IN-5
CAS:<p>Proteasome-IN-5, also known as compound 5, acts as a proteasome inhibitor [1].</p>Formula:C20H30BN5O7Purity:98%Color and Shape:SolidMolecular weight:463.29Collagen proline hydroxylase inhibitor
CAS:<p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>Formula:C18H18N4O4Purity:98%Color and Shape:SolidMolecular weight:354.36Ro 31-9790
CAS:<p>Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).</p>Formula:C15H29N3O4Purity:98%Color and Shape:SolidMolecular weight:315.41ONO 4817
CAS:<p>ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.</p>Formula:C22H28N2O6Color and Shape:SolidMolecular weight:416.47MMP-7-IN-3
CAS:<p>MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.</p>Formula:C34H43ClF3N7O9SPurity:99.915%Color and Shape:SolidMolecular weight:818.26

