
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(38 products)
- Cysteine Protease(111 products)
- DPP-4(27 products)
- Glutaminase(46 products)
- HIV Protease(506 products)
- PAI-1(26 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(55 products)
- Proteasome(86 products)
- Serine Protease(54 products)
- p97(15 products)
Show 3 more subcategories
Found 985 products of "Proteases/Proteasome"
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MDL 27324
CAS:MDL 27324 is an inhibitor of human neutrophil elastase.Formula:C29H38F3N5O6SPurity:98%Color and Shape:SolidMolecular weight:641.7DS-1040 Tosylate
CAS:DS-1040 Tosylate is a thrombin-activated fibrinolysis inhibitor (TAFI) inhibitor and a fibrinolysis enhancer, used for researching thromboembolic diseases.Formula:C23H35N3O5SColor and Shape:SolidMolecular weight:465.61Berotralstat HCl
CAS:Berotralstat HCl is a selective plasma kallikrein inhibitor, reducing pain and swelling in HAE by blocking bradykinin release.Formula:C30H28Cl2F4N6OColor and Shape:SolidMolecular weight:635.4886Kallikrein-IN-2
CAS:Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein.Formula:C28H25F3N4O4Color and Shape:SolidMolecular weight:538.52Proteasome-IN-4
Proteasome-IN-4, a potent non-covalent inhibitor (IC50=8.39nM), halts cancer cell growth, useful for oncology studies.Formula:C44H58N6O5Color and Shape:SolidMolecular weight:750.97Cathepsin K inhibitor 3
CAS:Cathepsin K inhibitor 3: Selective, IC50 of 0.5 nM, good pharmacokinetics, potential for OA research.Formula:C30H31FN4O4SColor and Shape:SolidMolecular weight:562.65Phe-Pro-Ala-pNA
CAS:Phe-Pro-Ala-pNA is a chromogenic substrate utilized for assessing tripeptidyl peptidase activity.Formula:C23H27N5O5Color and Shape:SolidMolecular weight:453.49MMP-9 Inhibitor I
CAS:MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively).Formula:C27H33N3O5SColor and Shape:SolidMolecular weight:511.63SSR 69071
CAS:SSR69071: selective neutrophil elastase inhibitor, stronger for humans (Ki=0.0168 nM), may treat COPD, asthma, and reduce heart injury.Formula:C27H32N4O7SColor and Shape:SolidMolecular weight:556.63MDL-101146, (R)-
CAS:MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.Formula:C29H37F5N4O6Purity:98%Color and Shape:SolidMolecular weight:632.62XL-784 free base
CAS:XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).Formula:C21H22ClF2N3O8SPurity:98%Color and Shape:SolidMolecular weight:549.93Ravidasvir HCl
CAS:Ravidasvir, also known as PPI-668 and ASC16, is a second-generation, orally active, potent and selective HCV NS5A protein inhibitor.Formula:C42H52Cl2N8O6Color and Shape:SolidMolecular weight:835.828GSK-2485852
CAS:GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.Formula:C27H25BF2N2O6SColor and Shape:SolidMolecular weight:554.37MMP13-IN-3
CAS:MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.Formula:C24H22N4O5Purity:99.76%Color and Shape:SolidMolecular weight:446.46Ref: TM-T16124
1mg93.00€5mg205.00€10mg334.00€25mg587.00€50mg802.00€100mg1,108.00€1mL*10mM (DMSO)227.00€Cathepsin Inhibitor 2
CAS:Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).Formula:C19H21F6N3OPurity:98%Color and Shape:SolidMolecular weight:421.38XL-784
CAS:XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.Formula:C42H42Cl2F4MgN6O16S2Purity:98%Color and Shape:SolidMolecular weight:1122.15NCI-B16
CAS:NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].Formula:C27H26N8O4Color and Shape:SolidMolecular weight:526.55FK706
CAS:FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.Formula:C26H33F3N4NaO7Color and Shape:SolidMolecular weight:593.556Atecegatran metoxil
CAS:Atecegatran Metoxil (AZD0837), an oral thrombin inhibitor in development for stroke prevention in atrial fibrillation, is well-tolerated with favorable PK.Formula:C22H23ClF2N4O5Color and Shape:SolidMolecular weight:496.89Cyclotheonellazole A
CAS:Cyclotheonellazole A inhibits elastase (IC50=0.034nM) & chymotrypsin (IC50=0.62nM), a natural macrocyclic peptide.Formula:C44H54N9NaO14S2Color and Shape:SolidMolecular weight:1020.07Petesicatib
CAS:Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.Formula:C25H23F6N5O4SPurity:99.76%Color and Shape:SolidMolecular weight:603.54Ref: TM-T16474
1mg100.00€5mg236.00€10mg371.00€25mg735.00€50mg1,134.00€100mg1,468.00€200mg1,972.00€1mL*10mM (DMSO)314.00€Inogatran
CAS:Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.Formula:C21H38N6O4Purity:98%Color and Shape:SolidMolecular weight:438.56Z-PDLDA-NHOH
CAS:Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].Formula:C22H32N4O6Color and Shape:SolidMolecular weight:448.51Collagen proline hydroxylase inhibitor
CAS:Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.Formula:C18H18N4O4Purity:98%Color and Shape:SolidMolecular weight:354.36Cipemastat
CAS:Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).Formula:C22H36N4O5Purity:98%Color and Shape:SolidMolecular weight:436.55MMP-7-IN-2
CAS:MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.Formula:C28H40ClF3N6O9SPurity:97.82%Color and Shape:SolidMolecular weight:729.17LY52
CAS:LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.Formula:C22H24N4O6Purity:98%Color and Shape:SolidMolecular weight:440.45MK-3281
CAS:MK-3281: Oral, potent HCV NS5B inhibitor with promising properties and efficacy in replication trials, suitable for clinical use.Formula:C29H37N3O3Color and Shape:SolidMolecular weight:475.62PTC725
CAS:PTC725 is a selective HCV 1b replicons inhibitor. It has been shown to target the nonstructural protein 4B.Formula:C23H18F4N6O2SPurity:98%Color and Shape:SolidMolecular weight:518.49JTK-853
CAS:JTK-853: novel non-nucleoside HCV polymerase inhibitor with strong antiviral activity (EC50: 0.38 μM genotype 1a, 0.035 μM 1b).Formula:C28H23F7N6O4S2Purity:98%Color and Shape:SolidMolecular weight:704.64KCC009
CAS:KCC009 is a potent and selective Transglutaminase 2 Inhibitor.Formula:C21H22BrN3O5Color and Shape:SolidMolecular weight:476.32LMP7-IN-2
CAS:LMP7-IN-2 is an inhibitor of LMP7 and may be utilized in the treatment of associated inflammatory diseases and disorders [1].Formula:C28H27N3O3SColor and Shape:SolidMolecular weight:485.6(Rac)-Neurodegenerative Disorder-Targeting Compound 1
CAS:(Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.Formula:C28H28N4O4Color and Shape:SolidMolecular weight:484.55AZD-9819
CAS:AZD-9819 is a neutrophil elastase (HNE) inhibitor applicable for research into chronic obstructive pulmonary disease (COPD).Formula:C25H19F3N6O2Purity:100% - 99.18%Color and Shape:SolidMolecular weight:492.45Ro 31-9790
CAS:Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).Formula:C15H29N3O4Purity:98%Color and Shape:SolidMolecular weight:315.41Thrombin inhibitor 1
CAS:Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).Formula:C22H20Cl2F2N4O3Purity:98%Color and Shape:SolidMolecular weight:497.32AA74-1
CAS:AA74-1 is a potent, selective APEH inhibitor that significantly enhances T-cell proliferation by inhibiting APEH activity [1].Formula:C16H28N4O2Purity:98%Color and Shape:SolidMolecular weight:308.42JW 480
CAS:JW480 is a potent and selective inhibitor of KIAA1363, a serine hydrolase enzyme.Formula:C22H23NO2Purity:99.72%Color and Shape:SolidMolecular weight:333.42Ref: TM-T22883
2mg35.00€5mg49.00€10mg79.00€25mg160.00€50mg259.00€100mg416.00€200mg587.00€1mL*10mM (DMSO)57.00€H-Gly-Pro-Hyp-OH acetate
CAS:H-Gly-Pro-Hyp-OH, a peptide dipeptidyl peptidase 4 (DPP-4) inhibitor with an inhibition concentration (IC50) of 2.51 mM, effectively hinders the activity of the DPP-4 enzyme.Formula:C12H19N3O5C2H4O2Color and Shape:SolidMolecular weight:345.35LU-005i
CAS:LU-005i is a powerful inhibitor targeting the β5i subunit of immunoproteasomes, displaying a high potency with an IC 50 value of 6.6 nM, and exhibits selectivity by preferring β5i over the β5c subunit, which has an IC 50 value of 287 nM [1].Formula:C31H46N4O7Color and Shape:SolidMolecular weight:586.72MMP-9-IN-8
CAS:MMP-9-IN-8 (Compound 3), an MMP-9 inhibitor, exhibits inhibitory activities of 42.16% at 10 μM and 58.28% at 50 μM.Formula:C20H21F4N7OColor and Shape:SolidMolecular weight:451.42Flovagatran sodium
CAS:Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.Formula:C27H36BN3NaO7Purity:98%Color and Shape:SolidMolecular weight:548.4BMS-538305 HCl
CAS:BMS-538305 is a potent, selective inhibitor of dipeptidyl peptidase IV (DPP-IV).Formula:C17H27ClN2O2Color and Shape:SolidMolecular weight:326.86BAY-320
CAS:BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.Formula:C26H26F2N6O2Purity:98%Color and Shape:SolidMolecular weight:492.52Cardanol diene
CAS:Cardanol diene: phenol in cashew shells; anti-tyrosinase (IC50=52.5μM); used to make anti-E. coli biofilm complexes.Formula:C21H32OColor and Shape:SolidMolecular weight:300.48Z-LVG
CAS:Z-LVG, an irreversible cysteine protease inhibitor and a tripeptide derivative of cystatin C, serves as an inhibitor of viral replication and is utilized inFormula:C21H31N3O6Color and Shape:SolidMolecular weight:421.49SQ 32056
CAS:SQ 32056 is a cathepsin E inhibitor.Formula:C37H56N4O5Purity:98%Color and Shape:SolidMolecular weight:636.86BMS-189664 HCl
CAS:BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.Formula:C22H35ClN6O4SPurity:98%Color and Shape:SolidMolecular weight:515.07LONP1-IN-2
CAS:LONP1-IN-2: Potent LONP1 inhibitor, IC50=0.187μM; weak on 20S proteasome (>10μM); for cancer research.Formula:C16H27BN4O4Color and Shape:SolidMolecular weight:350.22ASP-8497
CAS:ASP8497 is a potent DPP-IV inhibitor enhancing GLP-1, used for type 2 diabetes and glucose intolerance.Formula:C18H27FN4O7SColor and Shape:SolidMolecular weight:462.49

