CymitQuimica logo
Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

Show 3 more subcategories

Found 985 products of "Proteases/Proteasome"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • MDL 27324

    CAS:
    MDL 27324 is an inhibitor of human neutrophil elastase.
    Formula:C29H38F3N5O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:641.7

    Ref: TM-T25782

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • DS-1040 Tosylate

    CAS:
    DS-1040 Tosylate is a thrombin-activated fibrinolysis inhibitor (TAFI) inhibitor and a fibrinolysis enhancer, used for researching thromboembolic diseases.
    Formula:C23H35N3O5S
    Color and Shape:Solid
    Molecular weight:465.61

    Ref: TM-T11100

    2mg
    111.00€
    25mg
    552.00€
    50mg
    718.00€
    100mg
    1,224.00€
  • Berotralstat HCl

    CAS:
    Berotralstat HCl is a selective plasma kallikrein inhibitor, reducing pain and swelling in HAE by blocking bradykinin release.
    Formula:C30H28Cl2F4N6O
    Color and Shape:Solid
    Molecular weight:635.4886

    Ref: TM-T70161

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • Kallikrein-IN-2

    CAS:
    Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein.
    Formula:C28H25F3N4O4
    Color and Shape:Solid
    Molecular weight:538.52

    Ref: TM-T63796

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Proteasome-IN-4


    Proteasome-IN-4, a potent non-covalent inhibitor (IC50=8.39nM), halts cancer cell growth, useful for oncology studies.
    Formula:C44H58N6O5
    Color and Shape:Solid
    Molecular weight:750.97

    Ref: TM-T72762

    25mg
    1,908.00€
    50mg
    2,502.00€
    100mg
    3,330.00€
  • Cathepsin K inhibitor 3

    CAS:
    Cathepsin K inhibitor 3: Selective, IC50 of 0.5 nM, good pharmacokinetics, potential for OA research.
    Formula:C30H31FN4O4S
    Color and Shape:Solid
    Molecular weight:562.65

    Ref: TM-T72296

    25mg
    1,908.00€
    50mg
    2,502.00€
    100mg
    3,330.00€
  • Phe-Pro-Ala-pNA

    CAS:
    Phe-Pro-Ala-pNA is a chromogenic substrate utilized for assessing tripeptidyl peptidase activity.
    Formula:C23H27N5O5
    Color and Shape:Solid
    Molecular weight:453.49

    Ref: TM-T84840

    10mg
    To inquire
    50mg
    To inquire
  • MMP-9 Inhibitor I

    CAS:
    MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively).
    Formula:C27H33N3O5S
    Color and Shape:Solid
    Molecular weight:511.63

    Ref: TM-T37726

    500µg
    474.00€
  • SSR 69071

    CAS:
    SSR69071: selective neutrophil elastase inhibitor, stronger for humans (Ki=0.0168 nM), may treat COPD, asthma, and reduce heart injury.
    Formula:C27H32N4O7S
    Color and Shape:Solid
    Molecular weight:556.63

    Ref: TM-T21989

    1mg
    105.00€
    5mg
    388.00€
    10mg
    750.00€
  • MDL-101146, (R)-

    CAS:
    MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.
    Formula:C29H37F5N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:632.62

    Ref: TM-T25784

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • XL-784 free base

    CAS:
    XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).
    Formula:C21H22ClF2N3O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:549.93

    Ref: TM-T13357

    25mg
    1,908.00€
    50mg
    2,502.00€
    100mg
    3,330.00€
  • Ravidasvir HCl

    CAS:
    Ravidasvir, also known as PPI-668 and ASC16, is a second-generation, orally active, potent and selective HCV NS5A protein inhibitor.
    Formula:C42H52Cl2N8O6
    Color and Shape:Solid
    Molecular weight:835.828

    Ref: TM-T71964

    1mg
    132.00€
    5mg
    587.00€
    10mg
    888.00€
    25mg
    1,945.00€
  • GSK-2485852

    CAS:
    GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.
    Formula:C27H25BF2N2O6S
    Color and Shape:Solid
    Molecular weight:554.37

    Ref: TM-T27463

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • MMP13-IN-3

    CAS:
    MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.
    Formula:C24H22N4O5
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:446.46

    Ref: TM-T16124

    1mg
    93.00€
    5mg
    205.00€
    10mg
    334.00€
    25mg
    587.00€
    50mg
    802.00€
    100mg
    1,108.00€
    1mL*10mM (DMSO)
    227.00€
  • Cathepsin Inhibitor 2

    CAS:
    Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).
    Formula:C19H21F6N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.38

    Ref: TM-T11554

    25mg
    1,872.00€
    50mg
    2,452.00€
    100mg
    3,230.00€
  • XL-784

    CAS:
    XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.
    Formula:C42H42Cl2F4MgN6O16S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1122.15

    Ref: TM-T13358

    2mg
    359.00€
    1mL*10mM (DMSO)
    33.00€
  • NCI-B16

    CAS:
    NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].
    Formula:C27H26N8O4
    Color and Shape:Solid
    Molecular weight:526.55

    Ref: TM-T81694

    5mg
    To inquire
    50mg
    To inquire
  • FK706

    CAS:
    FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.
    Formula:C26H33F3N4NaO7
    Color and Shape:Solid
    Molecular weight:593.556

    Ref: TM-T15285

    25mg
    1,378.00€
    50mg
    1,791.00€
    100mg
    2,872.00€
  • Atecegatran metoxil

    CAS:
    Atecegatran Metoxil (AZD0837), an oral thrombin inhibitor in development for stroke prevention in atrial fibrillation, is well-tolerated with favorable PK.
    Formula:C22H23ClF2N4O5
    Color and Shape:Solid
    Molecular weight:496.89

    Ref: TM-T30192

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • Cyclotheonellazole A

    CAS:
    Cyclotheonellazole A inhibits elastase (IC50=0.034nM) & chymotrypsin (IC50=0.62nM), a natural macrocyclic peptide.
    Formula:C44H54N9NaO14S2
    Color and Shape:Solid
    Molecular weight:1020.07

    Ref: TM-T76231

    5mg
    To inquire
    50mg
    To inquire
  • Petesicatib

    CAS:
    Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.
    Formula:C25H23F6N5O4S
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:603.54

    Ref: TM-T16474

    1mg
    100.00€
    5mg
    236.00€
    10mg
    371.00€
    25mg
    735.00€
    50mg
    1,134.00€
    100mg
    1,468.00€
    200mg
    1,972.00€
    1mL*10mM (DMSO)
    314.00€
  • Inogatran

    CAS:
    Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.
    Formula:C21H38N6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:438.56

    Ref: TM-T11659

    25mg
    1,908.00€
    50mg
    2,502.00€
    100mg
    3,330.00€
  • Z-PDLDA-NHOH

    CAS:
    Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].
    Formula:C22H32N4O6
    Color and Shape:Solid
    Molecular weight:448.51

    Ref: TM-T80719

    5mg
    To inquire
    50mg
    To inquire
  • Collagen proline hydroxylase inhibitor

    CAS:
    Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.
    Formula:C18H18N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:354.36

    Ref: TM-T10862

    25mg
    690.00€
    50mg
    897.00€
    100mg
    1,378.00€
  • Cipemastat

    CAS:
    Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).
    Formula:C22H36N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:436.55

    Ref: TM-T10817

    25mg
    1,251.00€
    50mg
    1,629.00€
    100mg
    2,475.00€
  • MMP-7-IN-2

    CAS:
    MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.
    Formula:C28H40ClF3N6O9S
    Purity:97.82%
    Color and Shape:Solid
    Molecular weight:729.17

    Ref: TM-T78181

    1mg
    240.00€
    5mg
    590.00€
    10mg
    1,064.00€
    25mg
    1,578.00€
    50mg
    2,118.00€
  • LY52

    CAS:
    LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.
    Formula:C22H24N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:440.45

    Ref: TM-T25765

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • MK-3281

    CAS:
    MK-3281: Oral, potent HCV NS5B inhibitor with promising properties and efficacy in replication trials, suitable for clinical use.
    Formula:C29H37N3O3
    Color and Shape:Solid
    Molecular weight:475.62

    Ref: TM-T33432

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • PTC725

    CAS:
    PTC725 is a selective HCV 1b replicons inhibitor. It has been shown to target the nonstructural protein 4B.
    Formula:C23H18F4N6O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:518.49

    Ref: TM-T24682

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • JTK-853

    CAS:
    JTK-853: novel non-nucleoside HCV polymerase inhibitor with strong antiviral activity (EC50: 0.38 μM genotype 1a, 0.035 μM 1b).
    Formula:C28H23F7N6O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:704.64

    Ref: TM-T15631

    25mg
    4,374.00€
    50mg
    5,686.00€
    100mg
    7,397.00€
  • KCC009

    CAS:
    KCC009 is a potent and selective Transglutaminase 2 Inhibitor.
    Formula:C21H22BrN3O5
    Color and Shape:Solid
    Molecular weight:476.32

    Ref: TM-T27717

    25mg
    690.00€
    50mg
    897.00€
    100mg
    1,341.00€
  • LMP7-IN-2

    CAS:
    LMP7-IN-2 is an inhibitor of LMP7 and may be utilized in the treatment of associated inflammatory diseases and disorders [1].
    Formula:C28H27N3O3S
    Color and Shape:Solid
    Molecular weight:485.6

    Ref: TM-T81921

    5mg
    To inquire
    50mg
    To inquire
  • (Rac)-Neurodegenerative Disorder-Targeting Compound 1

    CAS:
    (Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.
    Formula:C28H28N4O4
    Color and Shape:Solid
    Molecular weight:484.55

    Ref: TM-T83527

    5mg
    To inquire
    50mg
    To inquire
  • AZD-9819

    CAS:
    AZD-9819 is a neutrophil elastase (HNE) inhibitor applicable for research into chronic obstructive pulmonary disease (COPD).
    Formula:C25H19F3N6O2
    Purity:100% - 99.18%
    Color and Shape:Solid
    Molecular weight:492.45

    Ref: TM-T68240

    1mg
    411.00€
    5mg
    954.00€
    10mg
    1,279.00€
    25mg
    1,873.00€
    50mg
    2,547.00€
  • Ro 31-9790

    CAS:
    Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).
    Formula:C15H29N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:315.41

    Ref: TM-T12762

    25mg
    1,730.00€
    50mg
    2,262.00€
    100mg
    2,945.00€
  • Thrombin inhibitor 1

    CAS:
    Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).
    Formula:C22H20Cl2F2N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:497.32

    Ref: TM-T10081

    25mg
    1,908.00€
    50mg
    2,502.00€
    100mg
    3,330.00€
  • AA74-1

    CAS:
    AA74-1 is a potent, selective APEH inhibitor that significantly enhances T-cell proliferation by inhibiting APEH activity [1].
    Formula:C16H28N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:308.42

    Ref: TM-T78134

    5mg
    To inquire
    50mg
    To inquire
  • JW 480

    CAS:
    JW480 is a potent and selective inhibitor of KIAA1363, a serine hydrolase enzyme.
    Formula:C22H23NO2
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:333.42

    Ref: TM-T22883

    2mg
    35.00€
    5mg
    49.00€
    10mg
    79.00€
    25mg
    160.00€
    50mg
    259.00€
    100mg
    416.00€
    200mg
    587.00€
    1mL*10mM (DMSO)
    57.00€
  • H-Gly-Pro-Hyp-OH acetate

    CAS:
    H-Gly-Pro-Hyp-OH, a peptide dipeptidyl peptidase 4 (DPP-4) inhibitor with an inhibition concentration (IC50) of 2.51 mM, effectively hinders the activity of the DPP-4 enzyme.
    Formula:C12H19N3O5C2H4O2
    Color and Shape:Solid
    Molecular weight:345.35

    Ref: TM-T84970

    10mg
    To inquire
    50mg
    To inquire
  • LU-005i

    CAS:
    LU-005i is a powerful inhibitor targeting the β5i subunit of immunoproteasomes, displaying a high potency with an IC 50 value of 6.6 nM, and exhibits selectivity by preferring β5i over the β5c subunit, which has an IC 50 value of 287 nM [1].
    Formula:C31H46N4O7
    Color and Shape:Solid
    Molecular weight:586.72

    Ref: TM-T84755

    10mg
    To inquire
    50mg
    To inquire
  • MMP-9-IN-8

    CAS:
    MMP-9-IN-8 (Compound 3), an MMP-9 inhibitor, exhibits inhibitory activities of 42.16% at 10 μM and 58.28% at 50 μM.
    Formula:C20H21F4N7O
    Color and Shape:Solid
    Molecular weight:451.42

    Ref: TM-T81777

    5mg
    To inquire
    50mg
    To inquire
  • Flovagatran sodium

    CAS:
    Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.
    Formula:C27H36BN3NaO7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:548.4

    Ref: TM-T27336

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • BMS-538305 HCl

    CAS:
    BMS-538305 is a potent, selective inhibitor of dipeptidyl peptidase IV (DPP-IV).
    Formula:C17H27ClN2O2
    Color and Shape:Solid
    Molecular weight:326.86

    Ref: TM-T26850

    25mg
    1,773.00€
    50mg
    2,322.00€
    100mg
    3,060.00€
  • BAY-320

    CAS:
    BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.
    Formula:C26H26F2N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:492.52

    Ref: TM-T14503

    25mg
    1,485.00€
    50mg
    1,935.00€
    100mg
    2,980.00€
  • Cardanol diene

    CAS:
    Cardanol diene: phenol in cashew shells; anti-tyrosinase (IC50=52.5μM); used to make anti-E. coli biofilm complexes.
    Formula:C21H32O
    Color and Shape:Solid
    Molecular weight:300.48

    Ref: TM-T71813

    1mg
    530.00€
    5mg
    2,395.00€
    10mg
    4,438.00€
    500µg
    284.00€
  • Z-LVG

    CAS:
    Z-LVG, an irreversible cysteine protease inhibitor and a tripeptide derivative of cystatin C, serves as an inhibitor of viral replication and is utilized in
    Formula:C21H31N3O6
    Color and Shape:Solid
    Molecular weight:421.49

    Ref: TM-T80722

    5mg
    To inquire
    50mg
    To inquire
  • SQ 32056

    CAS:
    SQ 32056 is a cathepsin E inhibitor.
    Formula:C37H56N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:636.86

    Ref: TM-T26217

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • BMS-189664 HCl

    CAS:
    BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.
    Formula:C22H35ClN6O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:515.07

    Ref: TM-T25165L

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • LONP1-IN-2

    CAS:
    LONP1-IN-2: Potent LONP1 inhibitor, IC50=0.187μM; weak on 20S proteasome (>10μM); for cancer research.
    Formula:C16H27BN4O4
    Color and Shape:Solid
    Molecular weight:350.22

    Ref: TM-T73191

    10mg
    2,788.00€
    25mg
    To inquire
  • ASP-8497

    CAS:
    ASP8497 is a potent DPP-IV inhibitor enhancing GLP-1, used for type 2 diabetes and glucose intolerance.
    Formula:C18H27FN4O7S
    Color and Shape:Solid
    Molecular weight:462.49

    Ref: TM-T30169

    25mg
    1,908.00€
    50mg
    2,502.00€
    100mg
    3,330.00€