CymitQuimica logo
Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

Show 3 more subcategories

Found 994 products of "Proteases/Proteasome"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • GSK2336805

    CAS:
    GSK-2336805, an HCV NS5A inhibitor, is effective against genotypes 1, 4, 5, and some of 6.
    Formula:C42H52N8O8
    Color and Shape:Solid
    Molecular weight:796.91

    Ref: TM-T27461

    25mg
    2,178.00€
    50mg
    2,862.00€
    100mg
    3,870.00€
  • Tyrosinase-IN-38


    Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.
    Color and Shape:Odour Solid

    Ref: TM-T200602

    10mg
    To inquire
    50mg
    To inquire
  • Aristololactam IIIa

    CAS:
    Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.
    Formula:C16H9NO4
    Color and Shape:Solid
    Molecular weight:279.25

    Ref: TM-T75619

    5mg
    To inquire
    50mg
    To inquire
  • Iso-VQA-ACC acetate


    Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.
    Color and Shape:Odour Solid

    Ref: TM-TP2884

    10mg
    To inquire
    50mg
    To inquire
  • HIV-1 TAT (48-60) Acetate


    Lilotomab (HH1) is a murine anti-CD37 antibody that can be used to synthesize anti-CD37 antibody-radionuclide couplings.
    Formula:C72H135N35O18
    Purity:99.93%
    Color and Shape:Soild
    Molecular weight:1779.07

    Ref: TM-T75964L

    1mg
    74.00€
    5mg
    150.00€
    10mg
    214.00€
    25mg
    364.00€
    50mg
    536.00€
  • MK-6169

    CAS:
    MK-6169 is an effective Pan-Genotype Hepatitis C Virus NS5A inhibitor. It also has Optimized Activity against Common Resistance-Associated Substitutions.
    Formula:C54H62FN9O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1016.2

    Ref: TM-T24476

    25mg
    1,369.00€
  • NIM811

    CAS:
    NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.
    Formula:C62H111N11O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1202.635

    Ref: TM-T12226

    5mg
    To inquire
  • GSK2818713

    CAS:
    GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.
    Formula:C46H56N8O8
    Color and Shape:Solid
    Molecular weight:849.002

    Ref: TM-T38858

    5mg
    922.00€
  • Sadopeptins A


    Sadopeptins A, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].
    Formula:C49H71N9O13S
    Color and Shape:Solid
    Molecular weight:1026.21

    Ref: TM-T75623

    5mg
    To inquire
    50mg
    To inquire
  • PSI-7409

    CAS:

    PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).

    Formula:C10H16FN2O14P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:500.16

    Ref: TM-T12572

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Talabostat

    CAS:
    Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.
    Formula:C9H19BN2O3
    Color and Shape:Solid
    Molecular weight:214.07

    Ref: TM-T37861

    5mg
    100.00€
    10mg
    148.00€
    50mg
    545.00€
  • Bortezomib analog


    Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.
    Color and Shape:Odour Solid

    Ref: TM-T200528

    10mg
    To inquire
    50mg
    To inquire
  • Neutrophil elastase inhibitor 4


    Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.
    Formula:C20H21N3O5
    Color and Shape:Solid
    Molecular weight:383.4

    Ref: TM-T79397

    5mg
    To inquire
    50mg
    To inquire
  • Tyrosinase-IN-36


    Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.
    Color and Shape:Odour Solid

    Ref: TM-T200699

    10mg
    To inquire
    50mg
    To inquire
  • PS 915

    CAS:
    PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.
    Formula:C27H36ClN7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:590.08

    Ref: TM-T24674

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Ellipyrone B


    Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50
    Formula:C25H38O7
    Color and Shape:Solid
    Molecular weight:450.57

    Ref: TM-T75493

    5mg
    To inquire
    50mg
    To inquire
  • PSI-353661

    CAS:
    PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.
    Formula:C24H32FN6O8P
    Color and Shape:Solid
    Molecular weight:582.52

    Ref: TM-T74301

    5mg
    To inquire
    50mg
    To inquire
  • NS5A-IN-1


    NS5A-IN-1 is a proagent of the HCV NS5A inhibitor Pibrentasvir (ABT-530).
    Formula:C72H86F5N10O14P
    Color and Shape:Solid
    Molecular weight:1441.48

    Ref: TM-T74403

    5mg
    To inquire
    50mg
    To inquire
  • HCV-IN-7 hydrochloride

    CAS:
    HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.
    Formula:C40H50Cl2N8O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:841.85

    Ref: TM-T11548L

    25mg
    1,369.00€
  • Ichorcumab

    CAS:

    Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.

    Color and Shape:Liquid

    Ref: TM-T9901A-779

    1mg
    To inquire
    5mg
    To inquire
  • FFAGLDD


    "FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."
    Formula:C37H49N7O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:783.82

    Ref: TM-TP1545

    2mg
    71.00€
    5mg
    92.00€
    10mg
    131.00€
    25mg
    229.00€
    50mg
    343.00€
    100mg
    517.00€
  • Relacatib

    CAS:
    Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.
    Formula:C27H32N4O6S
    Color and Shape:Solid
    Molecular weight:540.64

    Ref: TM-T40463

    5mg
    1,773.00€
  • STK33-IN-1

    CAS:
    STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.
    Formula:C24H27N7O2
    Color and Shape:Solid
    Molecular weight:445.527

    Ref: TM-T38835

    5mg
    873.00€
  • Calpain Inhibitor-1

    CAS:
    Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.
    Formula:C19H17FN6O5S
    Color and Shape:Solid
    Molecular weight:460.44

    Ref: TM-T38931

    5mg
    3,780.00€
  • Tyrosinase-IN-34


    Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.
    Formula:C19H14BrClN4O
    Color and Shape:Solid
    Molecular weight:429.7

    Ref: TM-T89968

    10mg
    To inquire
    50mg
    To inquire
  • BAY 1217224

    CAS:

    BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.

    Formula:C24H27ClFN3O5
    Color and Shape:Solid
    Molecular weight:491.94

    Ref: TM-T39124

    25mg
    7,590.00€
  • Rivulariapeptolides 988


    Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).
    Formula:C50H68N8O13
    Color and Shape:Solid
    Molecular weight:989.12

    Ref: TM-T75651

    5mg
    To inquire
    50mg
    To inquire
  • GCPII-IN-1

    CAS:

    GCPII-IN-1, a potent PSMA inhibitor, binds with 44.3 nM affinity.

    Formula:C12H21N3O7
    Color and Shape:Solid
    Molecular weight:319.314

    Ref: TM-T38420

    5mg
    922.00€
  • LXE408 fumarate


    LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.

    Formula:C27H22FN7O6
    Purity:99.89%
    Color and Shape:Soild
    Molecular weight:559.51

    Ref: TM-T39214L

    1mg
    315.00€
    2mg
    472.00€
    5mg
    595.00€
    10mg
    947.00€
    25mg
    1,396.00€
    50mg
    1,890.00€
    100mg
    2,547.00€
  • PROTAC CG167


    PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47

    Ref: TM-T205234

    10mg
    To inquire
    50mg
    To inquire
  • Ac-Phe-Gly-pNA

    CAS:
    Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .
    Formula:C19H20N4O5
    Color and Shape:Solid
    Molecular weight:384.39

    Ref: TM-T74692

    5mg
    To inquire
    50mg
    To inquire
  • Anticancer agent 114


    Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.
    Formula:C28H33BF6N2O7
    Color and Shape:Solid
    Molecular weight:634.37

    Ref: TM-T74839

    5mg
    To inquire
    50mg
    To inquire
  • Fotagliptin

    CAS:
    Fotagliptin is a dipeptidyl peptidase IV inhibitor.
    Formula:C17H19FN6O
    Color and Shape:Solid
    Molecular weight:342.37

    Ref: TM-T27353

    5mg
    1,414.00€
    50mg
    2,862.00€
    100mg
    3,870.00€
  • N-CBZ-Phe-Arg-AMC

    CAS:
    Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.
    Formula:C33H36N6O6
    Purity:98%
    Color and Shape:White To Off-White Powder
    Molecular weight:612.68

    Ref: TM-TP1013

    100mg
    To inquire
    500mg
    To inquire
  • BPHA

    CAS:
    BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.
    Formula:C21H20N2O4S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:396.46

    Ref: TM-T36712

    1mg
    167.00€
    5mg
    442.00€
    10mg
    620.00€
    25mg
    954.00€
    50mg
    1,305.00€
    100mg
    1,738.00€
    200mg
    2,322.00€
    1mL*10mM (DMSO)
    442.00€
  • HIV-1 inhibitor-6 

    CAS:
    HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing
    Formula:C14H10N4O4S
    Purity:99.33%
    Color and Shape:Solid
    Molecular weight:330.32

    Ref: TM-T9854

    1mg
    75.00€
    5mg
    169.00€
    10mg
    284.00€
    25mg
    452.00€
    50mg
    645.00€
    100mg
    867.00€
    500mg
    To inquire
  • Sadopeptins B


    Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].
    Formula:C48H69N9O13S
    Color and Shape:Solid
    Molecular weight:1012.18

    Ref: TM-T75624

    5mg
    To inquire
    50mg
    To inquire
  • TMC647055 Choline salt


    TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).
    Formula:C37H53N5O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:727.91

    Ref: TM-T13170

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Phaeosphaone D

    CAS:
    Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).
    Formula:C20H27N3O3S2
    Color and Shape:Solid
    Molecular weight:421.58

    Ref: TM-T75470

    5mg
    To inquire
    50mg
    To inquire
  • Tyrosinase/elastase-IN-1


    Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastase
    Formula:C33H52O5
    Color and Shape:Solid
    Molecular weight:528.76

    Ref: TM-T74243

    5mg
    To inquire
    50mg
    To inquire
  • PF 00356231

    CAS:

    PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).

    Formula:C25H20N2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:428.5

    Ref: TM-T60071

    1mg
    185.00€
    5mg
    415.00€
    10mg
    622.00€
    25mg
    1,119.00€
    50mg
    1,679.00€
    100mg
    2,520.00€
    200mg
    3,780.00€
  • Berotralstat

    CAS:
    Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.
    Formula:C30H26F4N6O
    Color and Shape:Solid
    Molecular weight:562.56

    Ref: TM-T35869

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • MMP-9-IN-6

    CAS:
    MMP-9-IN-6: MMP-9 inhibitor, IC50 of 50 µM, anti-ulcer, potential anti-tumor, for tissue repair studies.
    Formula:C25H19NO2
    Purity:98.96%
    Color and Shape:Soild
    Molecular weight:365.42

    Ref: TM-T77617

    1mg
    70.00€
    5mg
    138.00€
    10mg
    195.00€
    25mg
    309.00€
    50mg
    408.00€
    100mg
    562.00€
    200mg
    743.00€
  • Sofosbuvir impurity J

    CAS:
    Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
    Formula:C22H30FN4O8P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.47

    Ref: TM-T12965

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Elastatinal

    CAS:
    Elastatinal is an elastase inhibitor. It is found in culture filtrates of various species of actinomyces.
    Formula:C21H36N8O7
    Color and Shape:Yellowish Solid
    Molecular weight:512.56

    Ref: TM-T20130

    5mg
    304.00€
    10mg
    575.00€
    25mg
    1,251.00€
  • Histatin 5

    CAS:
    Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.
    Formula:C133H195N51O33
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3036.29

    Ref: TM-TP1741

    1mg
    163.00€
    5mg
    562.00€
    10mg
    892.00€
  • Dutogliptin tartrate

    CAS:
    Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
    Formula:C14H26BN3O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:391.18

    Ref: TM-T11127

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • EP 171

    CAS:
    EP 171 is a potent agonist of TP-receptors.
    Formula:C23H29FO5
    Color and Shape:Solid
    Molecular weight:404.47

    Ref: TM-T27273

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • 15,16-Dihydrotanshindiol C


    15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.
    Formula:C18H18O5
    Color and Shape:Solid
    Molecular weight:314.337

    Ref: TM-T123985

    1mg
    To inquire
    5mg
    To inquire
  • CRA-2059 TFA


    CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].
    Color and Shape:Solid

    Ref: TM-T38052

    5mg
    1,295.00€