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Proteases/Proteasome

Proteases/Proteasome

Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.

Subcategories of "Proteases/Proteasome"

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Found 899 products for "Proteases/Proteasome".

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  • Anticancer agent 114


    Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.
    Formula:C28H33BF6N2O7
    Color and Shape:Solid
    Molecular weight:634.37

    Ref: TM-T74839

    5mg
    To inquire
    50mg
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  • BAY 1217224

    CAS:
    BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.
    Formula:C24H27ClFN3O5
    Color and Shape:Solid
    Molecular weight:491.94

    Ref: TM-T39124

    25mg
    7,192.00€
  • KKI-5

    CAS:
    KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.
    Formula:C35H55N11O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:773.88

    Ref: TM-TP1792

    1mg
    60.00€
    5mg
    163.00€
    10mg
    284.00€
  • APC-6860

    CAS:
    APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.
    Formula:C9H7IN2S
    Color and Shape:Solid
    Molecular weight:302.13

    Ref: TM-T39029

    5mg
    873.00€
  • PF 00356231

    CAS:
    PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).
    Formula:C25H20N2O3S
    Purity:99.35%
    Color and Shape:Solid
    Molecular weight:428.5

    Ref: TM-T60071

    1mg
    175.00€
    5mg
    394.00€
    10mg
    590.00€
    25mg
    1,060.00€
    50mg
    1,591.00€
    100mg
    2,387.00€
    200mg
    3,580.00€
  • CDD-3290


    CDD-3290 serves as a functional therapeutic tool specifically designed to enable the precise detection and inhibition of the proteolytic activity of PSA which plays a pivotal role in the progression of prostate cancer during strictly monitored laboratory observation periods and molecular investigations to evaluate the pharmacological potential of targeted kallikrein inhibition in specialized preclinical research environments.
    Formula:C17H14N6O2
    Purity:99.13%
    Color and Shape:White Solid
    Molecular weight:334.33

    Ref: TM-T89314

    1mg
    172.00€
  • Dihydrofuran-3(2H)-one

    CAS:
    Dihydrofuran-3(2H)-one, with CAS No. 22929-52-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Dihydrofuran-3(2H)-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
    Formula:C4H6O2
    Purity:99.92%
    Molecular weight:86.09

    Ref: TM-T7228

    1mL*10mM (DMSO)
    33.00€
    200mg
    33.00€
  • BPHA

    CAS:
    BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.
    Formula:C21H20N2O4S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:396.46

    Ref: TM-T36712

    1mg
    167.00€
    5mg
    442.00€
    1mL*10mM (DMSO)
    442.00€
    10mg
    620.00€
    25mg
    954.00€
    50mg
    1,305.00€
    100mg
    1,738.00€
    200mg
    2,322.00€
  • AMG-222

    CAS:
    AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.
    Formula:C32H39N9O3
    Color and Shape:Solid
    Molecular weight:597.71

    Ref: TM-T29970

    25mg
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    50mg
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    100mg
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  • PS 915

    CAS:
    PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.
    Formula:C27H36ClN7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:590.08

    Ref: TM-T24674

    25mg
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    50mg
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    100mg
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  • Rivulariapeptolides 1185


    Rivulariapeptolides 1185 inhibits serine proteases; IC50: chymotrypsin 13.17 nM, elastase 23.59 nM, proteinase K 55.26 nM.
    Formula:C61H87N9O15
    Color and Shape:Solid
    Molecular weight:1186.39

    Ref: TM-T75649

    5mg
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    50mg
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  • LXE408 fumarate


    LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.
    Formula:C27H22FN7O6
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:559.51

    Ref: TM-T39214L

    1mg
    299.00€
    2mg
    447.00€
    5mg
    563.00€
    1mL*10mM (DMSO)
    830.00€
    10mg
    897.00€
    25mg
    1,324.00€
    50mg
    1,791.00€
    100mg
    2,412.00€
  • Recombinant Proteinase K


    Recombinant Proteinase K: serine protease, cleaves carboxy-terminus peptides, digests proteins, purifies nucleic acids.
    Color and Shape:Solid

    Ref: TM-T76202

    5mg
    To inquire
    50mg
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  • Tyrosinase-IN-38


    Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.
    Color and Shape:Odour Solid

    Ref: TM-T200602

    10mg
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    50mg
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  • Barbituric acid

    CAS:
    Barbituric acid is a pyrimidine derivative and the basic skeleton of barbiturate drugs, barbiturate drugs and other heterocyclic compounds.
    Formula:C4H4N2O3
    Purity:99.83%
    Molecular weight:128.09

    Ref: TM-T205940

    50mg
    58.00€
    100mg
    87.00€
  • Iso-VQA-ACC acetate


    Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.
    Color and Shape:Odour Solid

    Ref: TM-TP2884

    10mg
    To inquire
    50mg
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  • AR-H067637

    CAS:
    AR-H067637 is a fast-acting, reversible thrombin inhibitor with K(i) 2-4 nM; it also reduces clot-bound thrombin and platelet activation/aggregation.
    Formula:C21H21ClF2N4O4
    Color and Shape:Solid
    Molecular weight:466.87

    Ref: TM-T26657

    25mg
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    50mg
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    100mg
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  • Monodes(N-carboxymethyl)valine Daclatasvir

    CAS:
    Monodes(N-carboxymethyl)valine Daclatasvir, or Daclatasvir Impurity A, degrades Daclatasvir, a strong HCV NS5A inhibitor.
    Formula:C33H39N7O3
    Color and Shape:Solid
    Molecular weight:581.71

    Ref: TM-T37915

    5mg
    299.00€
    10mg
    507.00€
  • Carboxypeptidase C

    CAS:
    Carboxypeptidase C removes COOH-terminal amino acids and others in peptides for biochemical studies.
    Color and Shape:Solid

    Ref: TM-T76168

    5mg
    To inquire
    50mg
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  • Alisporivir

    CAS:
    Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.
    Formula:C63H113N11O12
    Purity:99.95%
    Color and Shape:White Solid
    Molecular weight:1216.64

    Ref: TM-T14180

    1mg
    177.00€
    5mg
    447.00€
    10mg
    650.00€
  • TAPI1 acetate


    TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .
    Formula:C28H41N5O7
    Purity:98.82% - 99.94%
    Color and Shape:White Solid
    Molecular weight:559.65

    Ref: TM-T6009L

    1mg
    560.00€
    5mg
    1,198.00€
    10mg
    1,611.00€
    25mg
    2,385.00€
    50mg
    3,222.00€
  • Calpain Inhibitor-1

    CAS:
    Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.
    Formula:C19H17FN6O5S
    Color and Shape:Solid
    Molecular weight:460.44

    Ref: TM-T38931

    5mg
    3,780.00€
  • Bortezomib analog


    Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.
    Color and Shape:Odour Solid

    Ref: TM-T200528

    10mg
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    50mg
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  • Histatin 5 (TFA)(115966-68-2,free)


    Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM
    Formula:C135H196F3N51O35
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3150.32

    Ref: TM-TP1446

    1mg
    159.00€
    5mg
    532.00€
    10mg
    832.00€
    25mg
    1,489.00€
    50mg
    2,247.00€
  • Tyrosinase/elastase-IN-1


    Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastase
    Formula:C33H52O5
    Color and Shape:Solid
    Molecular weight:528.76

    Ref: TM-T74243

    5mg
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    50mg
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  • Tyrosinase-IN-36


    Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.
    Color and Shape:Odour Solid

    Ref: TM-T200699

    10mg
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    50mg
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  • PPACK Dihydrochloride

    CAS:
    PPACK Dihydrochloride is a selective thrombin inhibitor used in anticoagulation and serine protease studies.
    Formula:C21H33Cl3N6O3
    Purity:98%
    Color and Shape:White Solid
    Molecular weight:523.88

    Ref: TM-T23177

    5mg
    421.00€
  • PROTAC CG167


    PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)
    Formula:C65H79N13O11S
    Color and Shape:Solid
    Molecular weight:1250.47

    Ref: TM-T205234

    10mg
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    50mg
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  • Neutrophil elastase inhibitor 4


    Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.
    Formula:C20H21N3O5
    Color and Shape:Solid
    Molecular weight:383.4

    Ref: TM-T79397

    5mg
    To inquire
    50mg
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  • VD2173

    CAS:
    VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.
    Formula:C31H45N9O6S
    Color and Shape:Solid
    Molecular weight:671.81

    Ref: TM-T74390

    5mg
    To inquire
    50mg
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  • Adamtsostatin 4

    CAS:
    Adamtsostatin 4, an anti-angiogenic peptide, is utilized in research related to angiogenesis inhibition [1].
    Formula:C80H121N27O27S2
    Molecular weight:1957.11

    Ref: TM-T83170

    5mg
    To inquire
    50mg
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  • C3TD879

    CAS:
    C3TD879 is an active molecule that can be used in life science related research. The CAS number of C3TD879 is 2850259-33-3.
    Formula:C22H28N4O
    Molecular weight:364.48

    Ref: TM-T85987

    25mg
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    50mg
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    100mg
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  • Rivulariapeptolides 988


    Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).
    Formula:C50H68N8O13
    Color and Shape:Solid
    Molecular weight:989.12

    Ref: TM-T75651

    5mg
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    50mg
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  • Cathepsin C-IN-6


    Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase
    Formula:C24H35N5O4·xC2HF3O2
    Color and Shape:Solid

    Ref: TM-T79496

    5mg
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    50mg
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  • Talabostat

    CAS:
    Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.
    Formula:C9H19BN2O3
    Color and Shape:Solid
    Molecular weight:214.07

    Ref: TM-T37861

    5mg
    100.00€
    10mg
    148.00€
    50mg
    545.00€
  • DPP-4-IN-14


    DPP-4-IN-14 (compound 30) is an inhibitor of DPP-4, with an IC50 value of 12.82 nM.
    Formula:C33H27N7O3
    Color and Shape:Solid
    Molecular weight:569.613

    Ref: TM-T204855

    10mg
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    50mg
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  • Sofigatran

    CAS:
    Sofigatran (MCC-977) is an oral anticoagulant targeting thrombin for cardiovascular research.
    Formula:C24H44N4O4S
    Color and Shape:Solid
    Molecular weight:484.7

    Ref: TM-T39310

    5mg
    873.00€
  • Nostosin G


    Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).
    Formula:C25H33N5O6
    Color and Shape:Solid
    Molecular weight:499.56

    Ref: TM-T75647

    5mg
    To inquire
    50mg
    To inquire
  • RJS308


    RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)
    Formula:C63H75N13O11S
    Color and Shape:Solid
    Molecular weight:1222.42

    Ref: TM-T205591

    10mg
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    50mg
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  • Berotralstat

    CAS:
    Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.
    Formula:C30H26F4N6O
    Color and Shape:Solid
    Molecular weight:562.56

    Ref: TM-T35869

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Ac-Phe-Gly-pNA

    CAS:
    Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .
    Formula:C19H20N4O5
    Color and Shape:Solid
    Molecular weight:384.39

    Ref: TM-T74692

    5mg
    To inquire
    50mg
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  • FFAGLDD


    "FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."
    Formula:C37H49N7O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:783.82

    Ref: TM-TP1545

    2mg
    71.00€
    5mg
    92.00€
    10mg
    131.00€
    25mg
    229.00€
    50mg
    343.00€
    100mg
    517.00€
  • Tyrosinase-IN-43


    Tyrosinase-IN-43 (Compound 12j) is a competitive tyrosinase inhibitor with an IC50 value of 10.49 μM for tyrosinase. It exhibits significant antioxidant activity and can be used in the study and treatment of pigmentation-related conditions such as melasma, freckles, age spots, and post-inflammatory hyperpigmentation.

    Ref: TM-T211567

    10mg
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    50mg
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  • TMC647055 Choline salt


    TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).
    Formula:C37H53N5O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:727.91

    Ref: TM-T13170

    25mg
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    50mg
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    100mg
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  • α 1(I) Collagen (614-639), human

    CAS:
    This is a peptide inhibitor of collagen fibrillar matrix assembly.
    Formula:C134H189N37O39
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2942.16

    Ref: TM-TP1643

    100mg
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    500mg
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  • Ac-DEMEEC-OH

    CAS:
    Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.
    Formula:C29H44N6O16S2
    Color and Shape:Solid
    Molecular weight:796.82

    Ref: TM-TP2848

    10mg
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    50mg
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  • Collagen Type II Fragment

    CAS:
    Collagen Type II Fragment is a peptide with anti-inflammatory properties that effectively inhibits collagen-induced arthritis (CIA) in mice. It is useful for research focused on inflammation and immunity [1].
    Formula:C106H174N32O37
    Color and Shape:Solid
    Molecular weight:2488.71

    Ref: TM-TP2649

    10mg
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    50mg
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  • RXP470

    CAS:
    RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).
    Formula:C35H35BrClN4O10P
    Color and Shape:Solid
    Molecular weight:818

    Ref: TM-T28633

    5mg
    4,626.00€
  • Paritaprevir dihydrate

    CAS:
    Paritaprevir dihydrate: potent oral HCV NS3/4A inhibitor (EC50: 0.21-1 nM), SARS-CoV-3CL blocker (IC50: 1.31 μM), metabolized by CYP3A, boosted by Ritonavir.
    Formula:C40H47N7O9S
    Color and Shape:Solid
    Molecular weight:801.91

    Ref: TM-T73898

    5mg
    To inquire
    50mg
    To inquire
  • TP0597850

    CAS:
    TP0597850, a selective MMP2 inhibitor with an IC50 value of 0.22 nM, demonstrates a prolonged dissociation half-life from MMP2 (t1/2 = 265 minutes) [1].
    Formula:C41H57N9O13S
    Color and Shape:Solid
    Molecular weight:916.01

    Ref: TM-T74714

    5mg
    To inquire
    50mg
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