
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(34 products)
- Cysteine Protease(96 products)
- DPP-4(20 products)
- Glutaminase(40 products)
- HIV Protease(447 products)
- PAI-1(25 products)
- Protease Inhibitors(50 products)
- Protease-activated Receptor(54 products)
- Proteasome(94 products)
- Serine Protease(50 products)
- p97(14 products)
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Found 1045 products of "Proteases/Proteasome"
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Sadopeptins B
<p>Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].</p>Formula:C48H69N9O13SColor and Shape:SolidMolecular weight:1012.18Peptide 74
CAS:<p>Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.</p>Formula:C62H107N23O20S2Purity:98%Color and Shape:SolidMolecular weight:1558.79FFAGLDD TFA
<p>FFAGLDD TFA: MMP9 peptide for controlled DOX delivery to cytoplasm.</p>Formula:C39H50F3N7O14Purity:98%Color and Shape:SolidMolecular weight:897.85Monodes(N-carboxymethyl)valine Daclatasvir
CAS:<p>Monodes(N-carboxymethyl)valine Daclatasvir, or Daclatasvir Impurity A, degrades Daclatasvir, a strong HCV NS5A inhibitor.</p>Formula:C33H39N7O3Color and Shape:SolidMolecular weight:581.71Neutrophil elastase inhibitor 4
<p>Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.</p>Formula:C20H21N3O5Color and Shape:SolidMolecular weight:383.4BAY 1217224
CAS:<p>BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.</p>Formula:C24H27ClFN3O5Color and Shape:SolidMolecular weight:491.94Calpain Inhibitor-1
CAS:<p>Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.</p>Formula:C19H17FN6O5SColor and Shape:SolidMolecular weight:460.44TAPI1 acetate
<p>TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .</p>Formula:C28H41N5O7Purity:98.82% - 99.94%Color and Shape:SolidMolecular weight:559.65EP 171
CAS:<p>EP 171 is a potent agonist of TP-receptors.</p>Formula:C23H29FO5Color and Shape:SolidMolecular weight:404.47Histatin 5
CAS:<p>Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.</p>Formula:C133H195N51O33Purity:98%Color and Shape:SolidMolecular weight:3036.29Aristololactam IIIa
CAS:<p>Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.</p>Formula:C16H9NO4Color and Shape:SolidMolecular weight:279.25NS5A-IN-4
CAS:<p>NS5A-IN-4 (Compound 1.12) is a hepatitis C inhibitor effective against multiple genotypes, with IC50 values ranging from 1.2 to 2296 pM.</p>Formula:C47H48N8O6Color and Shape:SolidMolecular weight:820.93Imitrodast
CAS:<p>Imitrodast is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor for the treatment of immune system disorders, respiratory disorders, and</p>Formula:C13H12N2O2SPurity:98.39%Color and Shape:SolidMolecular weight:260.31AP-C2
CAS:<p>AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.</p>Formula:C18H16N4SPurity:99.87%Color and Shape:SoildMolecular weight:320.41Sofosbuvir impurity A
CAS:<p>Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.</p>Formula:C22H29FN3O9PPurity:98%Color and Shape:SolidMolecular weight:529.45Sucunamostat
CAS:<p>Sucunamostat is an L-aspartic acid enteropeptidase inhibitor.</p>Formula:C22H22N4O8Color and Shape:SolidMolecular weight:470.438Plasma kallikrein-IN-1
CAS:<p>Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.</p>Formula:C23H25F2N7OColor and Shape:SolidMolecular weight:453.498Sofosbuvir impurity J
CAS:<p>Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.</p>Formula:C22H30FN4O8PPurity:98%Color and Shape:SolidMolecular weight:528.47Acetyl-Calpastatin(184-210)(human)
CAS:<p>Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.</p>Formula:C142H230N36O44SPurity:98%Color and Shape:SolidMolecular weight:3177.65Berotralstat
CAS:<p>Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.</p>Formula:C30H26F4N6OColor and Shape:SolidMolecular weight:562.56PF 00356231
CAS:<p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>Formula:C25H20N2O3SPurity:99.35%Color and Shape:SolidMolecular weight:428.5Phaeosphaone D
CAS:<p>Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).</p>Formula:C20H27N3O3S2Color and Shape:SolidMolecular weight:421.58CRA-2059 hydrochloride
<p>CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].</p>Color and Shape:SolidHIV-1 inhibitor-6
CAS:<p>HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing</p>Formula:C14H10N4O4SPurity:99.33%Color and Shape:SolidMolecular weight:330.32Nostosin G
<p>Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).</p>Formula:C25H33N5O6Color and Shape:SolidMolecular weight:499.56BPHA
CAS:<p>BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.</p>Formula:C21H20N2O4SPurity:99.44%Color and Shape:SolidMolecular weight:396.46Enzyme-IN-1
CAS:<p>Enzyme-IN-1(compound 1)为基于肽的N端亲核试剂(Ntn)水解酶抑制剂,特别针对20S蛋白酶体的糜胰蛋白酶样活性(CT-L)进行抑制,可能展现出抗炎特性。</p>Formula:C36H50N4O7Color and Shape:SolidMolecular weight:650.8Sadopeptins A
<p>Sadopeptins A, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].</p>Formula:C49H71N9O13SColor and Shape:SolidMolecular weight:1026.21JC-10
CAS:<p>JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.</p>Formula:C25H29Cl2IN4Purity:95%Color and Shape:SolidMolecular weight:583.34Ellipyrone A
<p>Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).</p>Formula:C25H34O8Color and Shape:SolidMolecular weight:462.53Leptosin D
CAS:<p>Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)</p>Formula:C25H24N4O3S2Color and Shape:SolidMolecular weight:492.61Cys-TAT(47-57) acetate(583836-55-9 Free base)
<p>Cys-TAT(47-57) acetate is derived from the HIV-1 transactivating protein. Cys-TAT(47-57) acetate is an arginine rich peptide that can penetrate cells.</p>Formula:C69H128N34O16SPurity:95.1100%Color and Shape:SolidMolecular weight:1722.04CRA-2059 TFA
<p>CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].</p>Color and Shape:SolidCL 82198 hydrochloride
CAS:<p>CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.</p>Formula:C17H23ClN2O3Color and Shape:SolidMolecular weight:338.83Nitidanin
<p>Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.</p>Formula:C21H24O8Color and Shape:SolidMolecular weight:404.415RJS308
<p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>Formula:C63H75N13O11SColor and Shape:SolidMolecular weight:1222.42N-CBZ-Phe-Arg-AMC TFA
<p>N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.</p>Formula:C35H37F3N6O8Purity:99.88%Color and Shape:SolidMolecular weight:726.7RXP470
CAS:<p>RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).</p>Formula:C35H35BrClN4O10PColor and Shape:SolidMolecular weight:818L 659286
CAS:<p>L 659286 is one kind of cephalosporin derivative.</p>Formula:C17H21N5O7S2Color and Shape:SolidMolecular weight:471.51α 1(I) Collagen (614-639), human
CAS:<p>This is a peptide inhibitor of collagen fibrillar matrix assembly.</p>Formula:C134H189N37O39Purity:98%Color and Shape:SolidMolecular weight:2942.16Linagliptin Methyldimer
CAS:<p>Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.</p>Formula:C50H56N16O4Purity:97.23%Color and Shape:SolidMolecular weight:945.08Alisporivir
CAS:<p>Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.</p>Formula:C63H113N11O12Purity:99.95%Color and Shape:SolidMolecular weight:1216.64Ecallantide TFA
<p>Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of</p>Color and Shape:Odour SolidObtusifolin-2-O-glucoside
CAS:<p>Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].</p>Formula:C22H22O10Color and Shape:SolidMolecular weight:446.4DPP8/9-IN-1
<p>DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.</p>Color and Shape:Odour SolidRecombinant Proteinase K
<p>Recombinant Proteinase K: serine protease, cleaves carboxy-terminus peptides, digests proteins, purifies nucleic acids.</p>Color and Shape:SolidRivulariapeptolides 1155
<p>Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).</p>Formula:C59H81N9O15Color and Shape:SolidMolecular weight:1156.33Ac-DEMEEC-OH
CAS:<p>Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.</p>Formula:C29H44N6O16S2Color and Shape:SolidMolecular weight:796.82Relacatib
CAS:<p>Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.</p>Formula:C27H32N4O6SColor and Shape:SolidMolecular weight:540.64Tyrosinase-IN-32
<p>Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.</p>Formula:C15H19NO3Color and Shape:SolidMolecular weight:261.32

