
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase(41 products)
- Cysteine Protease(117 products)
- DPP-4(26 products)
- Glutaminase(44 products)
- HIV Protease(477 products)
- PAI-1(27 products)
- Protease Inhibitors(49 products)
- Protease-activated Receptor(55 products)
- Proteasome(84 products)
- Serine Protease(55 products)
- p97(15 products)
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Found 899 products for "Proteases/Proteasome".
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Anticancer agent 114
Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.Formula:C28H33BF6N2O7Color and Shape:SolidMolecular weight:634.37BAY 1217224
CAS:BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.Formula:C24H27ClFN3O5Color and Shape:SolidMolecular weight:491.94KKI-5
CAS:KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.Formula:C35H55N11O9Purity:98%Color and Shape:SolidMolecular weight:773.88APC-6860
CAS:APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.Formula:C9H7IN2SColor and Shape:SolidMolecular weight:302.13PF 00356231
CAS:PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).Formula:C25H20N2O3SPurity:99.35%Color and Shape:SolidMolecular weight:428.5CDD-3290
CDD-3290 serves as a functional therapeutic tool specifically designed to enable the precise detection and inhibition of the proteolytic activity of PSA which plays a pivotal role in the progression of prostate cancer during strictly monitored laboratory observation periods and molecular investigations to evaluate the pharmacological potential of targeted kallikrein inhibition in specialized preclinical research environments.Formula:C17H14N6O2Purity:99.13%Color and Shape:White SolidMolecular weight:334.33Dihydrofuran-3(2H)-one
CAS:Dihydrofuran-3(2H)-one, with CAS No. 22929-52-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Dihydrofuran-3(2H)-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C4H6O2Purity:99.92%Molecular weight:86.09BPHA
CAS:BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.Formula:C21H20N2O4SPurity:99.44%Color and Shape:SolidMolecular weight:396.46Ref: TM-T36712
1mg167.00€5mg442.00€1mL*10mM (DMSO)442.00€10mg620.00€25mg954.00€50mg1,305.00€100mg1,738.00€200mg2,322.00€AMG-222
CAS:AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.Formula:C32H39N9O3Color and Shape:SolidMolecular weight:597.71PS 915
CAS:PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.Formula:C27H36ClN7O6Purity:98%Color and Shape:SolidMolecular weight:590.08Rivulariapeptolides 1185
Rivulariapeptolides 1185 inhibits serine proteases; IC50: chymotrypsin 13.17 nM, elastase 23.59 nM, proteinase K 55.26 nM.Formula:C61H87N9O15Color and Shape:SolidMolecular weight:1186.39LXE408 fumarate
LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.Formula:C27H22FN7O6Purity:99.89%Color and Shape:SolidMolecular weight:559.51Ref: TM-T39214L
1mg299.00€2mg447.00€5mg563.00€1mL*10mM (DMSO)830.00€10mg897.00€25mg1,324.00€50mg1,791.00€100mg2,412.00€Recombinant Proteinase K
Recombinant Proteinase K: serine protease, cleaves carboxy-terminus peptides, digests proteins, purifies nucleic acids.Color and Shape:SolidTyrosinase-IN-38
Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.Color and Shape:Odour SolidBarbituric acid
CAS:Barbituric acid is a pyrimidine derivative and the basic skeleton of barbiturate drugs, barbiturate drugs and other heterocyclic compounds.Formula:C4H4N2O3Purity:99.83%Molecular weight:128.09Iso-VQA-ACC acetate
Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.Color and Shape:Odour SolidAR-H067637
CAS:AR-H067637 is a fast-acting, reversible thrombin inhibitor with K(i) 2-4 nM; it also reduces clot-bound thrombin and platelet activation/aggregation.Formula:C21H21ClF2N4O4Color and Shape:SolidMolecular weight:466.87Monodes(N-carboxymethyl)valine Daclatasvir
CAS:Monodes(N-carboxymethyl)valine Daclatasvir, or Daclatasvir Impurity A, degrades Daclatasvir, a strong HCV NS5A inhibitor.Formula:C33H39N7O3Color and Shape:SolidMolecular weight:581.71Carboxypeptidase C
CAS:Carboxypeptidase C removes COOH-terminal amino acids and others in peptides for biochemical studies.Color and Shape:SolidAlisporivir
CAS:Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.Formula:C63H113N11O12Purity:99.95%Color and Shape:White SolidMolecular weight:1216.64TAPI1 acetate
TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .Formula:C28H41N5O7Purity:98.82% - 99.94%Color and Shape:White SolidMolecular weight:559.65Calpain Inhibitor-1
CAS:Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.Formula:C19H17FN6O5SColor and Shape:SolidMolecular weight:460.44Bortezomib analog
Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.Color and Shape:Odour SolidHistatin 5 (TFA)(115966-68-2,free)
Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μMFormula:C135H196F3N51O35Purity:98%Color and Shape:SolidMolecular weight:3150.32Tyrosinase/elastase-IN-1
Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastaseFormula:C33H52O5Color and Shape:SolidMolecular weight:528.76Tyrosinase-IN-36
Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.Color and Shape:Odour SolidPPACK Dihydrochloride
CAS:PPACK Dihydrochloride is a selective thrombin inhibitor used in anticoagulation and serine protease studies.Formula:C21H33Cl3N6O3Purity:98%Color and Shape:White SolidMolecular weight:523.88PROTAC CG167
PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)Formula:C65H79N13O11SColor and Shape:SolidMolecular weight:1250.47Neutrophil elastase inhibitor 4
Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.Formula:C20H21N3O5Color and Shape:SolidMolecular weight:383.4VD2173
CAS:VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.Formula:C31H45N9O6SColor and Shape:SolidMolecular weight:671.81Adamtsostatin 4
CAS:Adamtsostatin 4, an anti-angiogenic peptide, is utilized in research related to angiogenesis inhibition [1].Formula:C80H121N27O27S2Molecular weight:1957.11C3TD879
CAS:C3TD879 is an active molecule that can be used in life science related research. The CAS number of C3TD879 is 2850259-33-3.Formula:C22H28N4OMolecular weight:364.48Rivulariapeptolides 988
Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).Formula:C50H68N8O13Color and Shape:SolidMolecular weight:989.12Cathepsin C-IN-6
Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastaseFormula:C24H35N5O4·xC2HF3O2Color and Shape:SolidTalabostat
CAS:Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.Formula:C9H19BN2O3Color and Shape:SolidMolecular weight:214.07DPP-4-IN-14
DPP-4-IN-14 (compound 30) is an inhibitor of DPP-4, with an IC50 value of 12.82 nM.Formula:C33H27N7O3Color and Shape:SolidMolecular weight:569.613Sofigatran
CAS:Sofigatran (MCC-977) is an oral anticoagulant targeting thrombin for cardiovascular research.Formula:C24H44N4O4SColor and Shape:SolidMolecular weight:484.7Nostosin G
Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).Formula:C25H33N5O6Color and Shape:SolidMolecular weight:499.56RJS308
RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)Formula:C63H75N13O11SColor and Shape:SolidMolecular weight:1222.42Berotralstat
CAS:Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.Formula:C30H26F4N6OColor and Shape:SolidMolecular weight:562.56Ac-Phe-Gly-pNA
CAS:Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .Formula:C19H20N4O5Color and Shape:SolidMolecular weight:384.39FFAGLDD
"FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."Formula:C37H49N7O12Purity:98%Color and Shape:SolidMolecular weight:783.82Tyrosinase-IN-43
Tyrosinase-IN-43 (Compound 12j) is a competitive tyrosinase inhibitor with an IC50 value of 10.49 μM for tyrosinase. It exhibits significant antioxidant activity and can be used in the study and treatment of pigmentation-related conditions such as melasma, freckles, age spots, and post-inflammatory hyperpigmentation.TMC647055 Choline salt
TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).Formula:C37H53N5O8SPurity:98%Color and Shape:SolidMolecular weight:727.91α 1(I) Collagen (614-639), human
CAS:This is a peptide inhibitor of collagen fibrillar matrix assembly.Formula:C134H189N37O39Purity:98%Color and Shape:SolidMolecular weight:2942.16Ac-DEMEEC-OH
CAS:Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.Formula:C29H44N6O16S2Color and Shape:SolidMolecular weight:796.82Collagen Type II Fragment
CAS:Collagen Type II Fragment is a peptide with anti-inflammatory properties that effectively inhibits collagen-induced arthritis (CIA) in mice. It is useful for research focused on inflammation and immunity [1].Formula:C106H174N32O37Color and Shape:SolidMolecular weight:2488.71RXP470
CAS:RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).Formula:C35H35BrClN4O10PColor and Shape:SolidMolecular weight:818Paritaprevir dihydrate
CAS:Paritaprevir dihydrate: potent oral HCV NS3/4A inhibitor (EC50: 0.21-1 nM), SARS-CoV-3CL blocker (IC50: 1.31 μM), metabolized by CYP3A, boosted by Ritonavir.Formula:C40H47N7O9SColor and Shape:SolidMolecular weight:801.91TP0597850
CAS:TP0597850, a selective MMP2 inhibitor with an IC50 value of 0.22 nM, demonstrates a prolonged dissociation half-life from MMP2 (t1/2 = 265 minutes) [1].Formula:C41H57N9O13SColor and Shape:SolidMolecular weight:916.01

