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Stem Cell and Derivatives

Stem Cell and Derivatives

Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.

Subcategories of "Stem Cell and Derivatives"

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Found 693 products of "Stem Cell and Derivatives"

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  • JAK-IN-3
    Targetmol
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    JAK-IN-3

    CAS:
    <p>JAK-IN-3 is a potent JAK inhibitor that inhibits JAK3, JAK1, TYK2, and JAK2, and can be used for the study of immune system disorders.</p>
    Formula:C18H20N4O3
    Purity:98.04% - 98.19%
    Color and Shape:Solid
    Molecular weight:340.38

    Ref: TM-T11704

  • GSK-3 inhibitor 1
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    GSK-3 inhibitor 1

    CAS:
    <p>GSK-3 inhibitor 1 is a GSK-3 inhibitor.</p>
    Formula:C22H17ClFN5O2
    Purity:98.42%
    Color and Shape:Solid
    Molecular weight:437.85

    Ref: TM-T11468

  • JAK2 JH2 binder-1
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    JAK2 JH2 binder-1

    CAS:
    <p>JAK2 JH2 binder-1: potent, selective, Ki=37.1 nM, potential for studying myeloproliferative neoplasms.</p>
    Formula:C29H25N7O6S
    Color and Shape:Solid
    Molecular weight:599.62

    Ref: TM-T64227

  • Tyk2-IN-17
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    Tyk2-IN-17

    CAS:
    <p>Tyk2-IN-17 (compound 185) effectively inhibits TYK2 [1].</p>
    Formula:C20H20F2N8O
    Color and Shape:Solid
    Molecular weight:426.42

    Ref: TM-T87586

  • Tyk2-IN-15
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    Tyk2-IN-15

    CAS:
    <p>Tyk2-IN-15 (Compound 97) is a selective inhibitor of tyrosine kinase 2 (Tyk2) with an IC50 value ≤ 10 nM for Tyk2-JH2. It is utilized in the research of inflammatory and autoimmune diseases [1].</p>
    Formula:C21H25F2N7O
    Color and Shape:Solid
    Molecular weight:429.47

    Ref: TM-T87584

  • TEAD-IN-20
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    TEAD-IN-20

    CAS:
    <p>TEAD-IN-20 is a TEAD inhibitor with IC50 values of 0.021 μM in TEAD4 FRET and 0.044 μM in TEAD4 MCF7-Tead cell lines. It has potential applications in cancer research.</p>
    Formula:C20H19F3N4O3
    Color and Shape:Solid
    Molecular weight:420.39

    Ref: TM-T207373

  • CymitQuimica logo
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    JAK-IN-23

    <p>"JAK-IN-23: oral dual JAK/STAT &amp; NF-κB inhibitor; JAK1 (IC50: 8.9 nM), JAK2 (15 nM), JAK3 (46.2 nM); for IBD research."</p>
    Formula:C23H22Cl2N4O
    Color and Shape:Solid
    Molecular weight:441.35

    Ref: TM-T62556

  • CymitQuimica logo
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    Ten01

    <p>Ten01 exhibits a 5.0 nM inhibition of JAK1 kinase.</p>
    Formula:C18H20F6N4O
    Color and Shape:Solid
    Molecular weight:422.37

    Ref: TM-T62257

  • (+)-ITD-1
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    (+)-ITD-1

    CAS:
    <p>(+)-ITD-1 is an inhibitor of TGF-β, effectively inhibiting TGF-β2 with an IC50 of 0.46 μM. It promotes the degradation of the TGF-β type II receptor (TGFBR2) and the differentiation of cardiomyocytes. Additionally, it suppresses the formation of the mesoderm during the early differentiation of mouse embryonic stem cells (mESCs).</p>
    Formula:C27H29NO3
    Color and Shape:Solid
    Molecular weight:415.52

    Ref: TM-T201672

  • CymitQuimica logo
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    JAK1/TYK2-IN-3

    <p>JAK1/TYK2-IN-3, orally active, selectively inhibits TYK2 (IC50: 6 nM), JAK1 (37 nM), JAK2 (140 nM), JAK3 (362 nM), and has anti-inflammatory effects.</p>
    Color and Shape:Solid

    Ref: TM-T64265

  • CDK8-IN-11
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    CDK8-IN-11

    CAS:
    <p>CDK8-IN-11 is a CDK8 inhibitor that demonstrates anti-proliferative activity against colon cancer cell lines and inhibits the activation of WNT/β-catenin.</p>
    Formula:C19H15F3N4O2
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:388.34

    Ref: TM-T61742

  • CEE321
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    CEE321

    CAS:
    <p>CEE321 is an effective pan-JAK inhibitor with an IC50 of 54 nM. It effectively inhibits biomarkers associated with atopic dermatitis.</p>
    Formula:C18H16ClN5O
    Color and Shape:Solid
    Molecular weight:353.806

    Ref: TM-T204824

  • TEAD-IN-10
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    TEAD-IN-10

    CAS:
    <p>TEAD-IN-10 (compound 15), a covalent inhibitor, exhibits selective and potent inhibitory activity against TEAD1 (IC 50 =14 nM), TEAD2 (IC 50 =179 nM), and TEAD3 (IC 50 =4 nM). This compound is utilized in cancer research [1].</p>
    Formula:C15H14F3NO
    Color and Shape:Solid
    Molecular weight:281.27

    Ref: TM-T87500

  • Londamocitinib
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    Londamocitinib

    CAS:
    <p>Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.</p>
    Formula:C28H31F2N7O4S
    Purity:98.64% - 99.56%
    Color and Shape:Solid
    Molecular weight:599.65

    Ref: TM-T11706

  • PMMB-187
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    PMMB-187

    CAS:
    <p>PMMB-187, a selective STAT3 inhibitor, exhibits an IC50 of 1.81 μM in MDA-MB-231 cells. This compound induces apoptosis in MDA-MB-231 cells by inhibiting STAT3 transcriptional activity and nuclear translocation, reducing mitochondrial membrane potential, increasing reactive oxygen species (ROS) production, and upregulating the expression of apoptosis-related proteins. PMMB-187 is useful for research in the field of cancer.</p>
    Formula:C27H23BrN2O6S2
    Color and Shape:Solid
    Molecular weight:615.52

    Ref: TM-T200126

  • (R)-9b
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    (R)-9b

    CAS:
    <p>(R)-9b is an effective inhibitor of the ACK1 tyrosine kinase (IC50=56 nM) and exhibits anticancer activity. It selectively targets ACK1 but also inhibits kinases in the JAK family, specifically JAK2 and Tyk2. (R)-9b is used in research related to hormone-regulated cancers, such as prostate cancer and breast cancer.</p>
    Formula:C20H27ClN6O
    Color and Shape:Solid
    Molecular weight:402.92

    Ref: TM-T201776

  • Tyk2-IN-14
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    Tyk2-IN-14

    CAS:
    <p>Tyk2-IN-14, a small molecule inhibitor of TYK2, is significant in treating inflammatory diseases and conditions linked to hypersecretion of IFNa and interferons [1].</p>
    Formula:C22H21N9O2
    Color and Shape:Solid
    Molecular weight:443.46

    Ref: TM-T87583

  • γ-Secretase modulator 11 hydrochloride
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    γ-Secretase modulator 11 hydrochloride

    CAS:
    <p>γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM).</p>
    Formula:C28H23ClF2N4O2
    Color and Shape:Solid
    Molecular weight:520.96

    Ref: TM-T63638

  • Notch inhibitor 1
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    Notch inhibitor 1

    CAS:
    <p>Notch inhibitor 1 blocks Notch 1/3 (IC50: 7.8/8.5 nM) and aids cancer research.</p>
    Formula:C26H25F7N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:574.49

    Ref: TM-T16341

  • Tyk2-IN-20
    Targetmol
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    Tyk2-IN-20

    CAS:
    <p>Tyk2-IN-20 (Example 289) is an effective inhibitor of Tyk2 with an IC50 value below 5 nM. Additionally, it inhibits JAK1, JAK2, and JAK3 with IC50 values under 100 nM. This compound is utilized for the research of inflammatory diseases.</p>
    Formula:C24H25N7O2
    Color and Shape:Solid
    Molecular weight:443.50

    Ref: TM-T201155