Stem Cell and Derivatives
Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.
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Subcategories of "Stem Cell and Derivatives"
Gamma-secretase
Hedgehog/Smoothened
Hippo pathway
JAK
Porcupine
ROCK
STAT
Stem Cells
TGF-beta/Smad
Wnt/beta-catenin
Show 2 more subcategories
Products of "Stem Cell and Derivatives"
SAG
CAS:912545-86-9
SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective.
Formula:
C28H28ClN3OS
Purity:
98.16% - 98.88%
Color and Shape:
Solid
Molecular weight:
490.06
Ref: TM-T1779
| 1mg | 51.00 € | ||
| 2mg | 70.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 269.00 € | ||
| 50mg | 368.00 € | ||
| 100mg | 547.00 € | ||
| 200mg | 783.00 € | ||
| 500mg | 1,160.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
SH5-07
CAS:1456632-41-9
SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).
Formula:
C29H28F5N3O5S
Purity:
95.54%
Color and Shape:
Solid
Molecular weight:
625.61
Ref: TM-TQ0052
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 192.00 € | ||
| 50mg | 285.00 € | ||
| 100mg | 414.00 € | ||
| 200mg | 584.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
GSK429286A
CAS:864082-47-3
GSK429286A (RHO-15) is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM).
Formula:
C21H16F4N4O2
Purity:
97.68% - 98.42%
Color and Shape:
Solid
Molecular weight:
432.37
Ref: TM-T2633
| 2mg | 41.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 134.00 € | ||
| 50mg | 206.00 € | ||
| 100mg | 348.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Glasdegib
CAS:1095173-27-5
Glasdegib (PF-04449913) (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of …
Formula:
C21H22N6O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
374.44
Ref: TM-T6514
| 1mg | 42.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 296.00 € | ||
| 50mg | 500.00 € | ||
| 100mg | 723.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
IWR-1
CAS:1127442-82-3
IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).
Formula:
C25H19N3O3
Purity:
98.46% - 99.82%
Color and Shape:
Solid
Molecular weight:
409.44
Ref: TM-T2651
| 5mg | 54.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 162.00 € | ||
| 50mg | 286.00 € | ||
| 100mg | 407.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Fz7-21
CAS:2247635-23-8
Fz7-21, a peptide antagonist of FZD7, inhibits Wnt/β-catenin signaling (IC50=50-100nM) in cells with WNT3A.
Formula:
C83H114N18O23S2
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
1796.03
Ref: TM-TP1263
| 1mg | 74.00 € | ||
| 5mg | 168.00 € | ||
| 10mg | 271.00 € | ||
| 25mg | 462.00 € | ||
| 50mg | 646.00 € | ||
| 100mg | 913.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
RO495
CAS:1258296-60-4
RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested …
Formula:
C17H14Cl2N6O
Purity:
99.4%
Color and Shape:
Solid
Molecular weight:
389.24
Ref: TM-T22416
| 1mg | 61.00 € | ||
| 2mg | 83.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | 499.00 € | ||
| 100mg | 672.00 € | ||
| 200mg | 904.00 € | ||
| 1mL*10mM (DMSO) | 135.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
HODHBt
CAS:28230-32-2
HODHBt is a STAT5-SUMO protein-protein interaction inhibitor.
Formula:
C7H5N3O2
Purity:
99.51% - 99.95%
Color and Shape:
Off-White To Yellow Solid
Molecular weight:
163.13
Ref: TM-T21267
| 100mg | 51.00 € | ||
| 200mg | 60.00 € | ||
| 500mg | 88.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
(E)-SIS3
CAS:521984-48-5
(E)-SIS3 (SIS3), a selective Smad3 inhibitor, can attenuate TGF-β1-dependent Smad3 phosphorylation and DNA binding
Formula:
C28H27N3O3·HCl
Purity:
95.64% - 98.83%
Color and Shape:
Solid
Molecular weight:
489.99
Ref: TM-T3636
| 1mg | 42.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 337.00 € | ||
| 50mg | 502.00 € | ||
| 100mg | 716.00 € | ||
| 500mg | 1,439.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
TDZD-8
CAS:327036-89-5
TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal …
Formula:
C10H10N2O2S
Purity:
97.13% - 99.48%
Color and Shape:
White Solid
Molecular weight:
222.26
Ref: TM-T6187
| 5mg | 49.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 122.00 € | ||
| 100mg | 184.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
HPI 1
CAS:599150-20-6
HPI 1 suppresses Hh pathway: IC50 = 1.5 μM (Shh, SAG), 4 μM (Gli2), 6 …
Formula:
C27H29NO6
Purity:
94.4%
Color and Shape:
Solid
Molecular weight:
463.52
Ref: TM-T22089
| 1mg | 46.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 132.00 € | ||
| 25mg | 214.00 € | ||
| 50mg | 319.00 € | ||
| 100mg | 462.00 € | ||
| 500mg | 1,003.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
SAR407899 hydrochloride
CAS:923262-96-8
SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 …
Formula:
C14H17ClN2O2
Purity:
98.01%
Color and Shape:
Solid
Molecular weight:
280.75
Ref: TM-T23308
| 5mg | 34.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 82.00 € | ||
| 50mg | 126.00 € | ||
| 100mg | 195.00 € | ||
| 200mg | 287.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
URMC-099
CAS:1229582-33-5
URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 - MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.
Formula:
C27H27N5
Purity:
98.43% - 99.32%
Color and Shape:
Solid
Molecular weight:
421.54
Ref: TM-T6057
| 5mg | 56.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 371.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
IM-12
CAS:1129669-05-1
IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.
Formula:
C22H20FN3O2
Purity:
100% - 99.71%
Color and Shape:
Solid
Molecular weight:
377.41
Ref: TM-T2261
| 5mg | 53.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 155.00 € | ||
| 50mg | 282.00 € | ||
| 100mg | 468.00 € | ||
| 500mg | 1,016.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
GSK180736A
CAS:817194-38-0
GSK180736A: GRK2 inhibitor (IC50 0.77µM), >100x selectivity vs GRKs, weak at PKA (IC50 30µM), strong …
Formula:
C19H16FN5O2
Purity:
98.16% - 98.44%
Color and Shape:
Solid
Molecular weight:
365.36
Ref: TM-T3513
| 1mg | 41.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 300.00 € | ||
| 100mg | 555.00 € | ||
| 500mg | 1,203.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Thiazovivin
CAS:1226056-71-8
Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.
Formula:
C15H13N5OS
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
311.36
Ref: TM-T2155
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 555.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Tideglusib
CAS:865854-05-3
Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory …
Formula:
C19H14N2O2S
Purity:
98.89% - 99.84%
Color and Shape:
Solid
Molecular weight:
334.39
Ref: TM-T3067
| 10mg | 46.00 € | ||
| 25mg | 76.00 € | ||
| 50mg | 112.00 € | ||
| 100mg | 185.00 € | ||
| 200mg | 279.00 € | ||
| 500mg | 482.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
FLI-06
CAS:313967-18-9
FLI-06 is a Notch signaling inhibitor (EC50: 2.3 μM).
Formula:
C25H30N2O5
Purity:
100% - ≥98%
Color and Shape:
Solid
Molecular weight:
438.52
Ref: TM-T3075
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 307.00 € | ||
| 100mg | 532.00 € | ||
| 500mg | 1,161.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
CCG-222740
CAS:1922098-69-8
CCG-222740 is an inhibitor of Rho/MRTF pathway
Formula:
C23H19ClF2N2O3
Purity:
98.76%
Color and Shape:
Solid
Molecular weight:
444.86
Ref: TM-T7764
| 2mg | 41.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 97.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 271.00 € | ||
| 100mg | 402.00 € | ||
| 200mg | 570.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
Pacritinib
CAS:937272-79-2
Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 …
Formula:
C28H32N4O3
Purity:
99.27% - ≥95%
Color and Shape:
Solid
Molecular weight:
472.58
Ref: TM-T6020
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 148.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 368.00 € | ||
| 500mg | 866.00 € |
Estimated delivery in United States, on Thursday 12 Dec 2024
