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Stem Cell and Derivatives

Stem Cell and Derivatives

Stem cell inhibitors are compounds that specifically target signaling pathways and proteins involved in the maintenance, differentiation, and proliferation of stem cells. These inhibitors are crucial for understanding stem cell biology and for developing strategies to manipulate stem cells for therapeutic purposes, such as regenerative medicine and cancer treatment. By controlling stem cell fate, these inhibitors can help guide stem cell differentiation into specific cell types or prevent unwanted cell growth. At CymitQuimica, we offer a selection of high-quality stem cell inhibitors to support your research in stem cell biology, developmental biology, and regenerative medicine.

Subcategories of "Stem Cell and Derivatives"

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Found 693 products of "Stem Cell and Derivatives"

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  • ML115

    CAS:
    <p>ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.</p>
    Formula:C15H15ClN2O4
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:322.74
  • BT-GSI


    <p>BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma &amp; anti-resorptive for multiple myeloma/bone disease research.</p>
    Formula:C26H46BrN5O10P2
    Color and Shape:Solid
    Molecular weight:730.52
  • GSM-1

    CAS:
    <p>GSM-1 is a modulator of γ-Secretase.</p>
    Formula:C26H31ClF3NO2
    Color and Shape:Solid
    Molecular weight:481.98
  • Itacnosertib (hydrocholide)

    CAS:
    <p>Itacnosertib hydrochloride acts as an inhibitor targeting JAK2, ACVR1 (ALK2), and ALK5 [1].</p>
    Formula:C26H29ClN8O
    Color and Shape:Solid
    Molecular weight:505.01
  • Brepocitinib

    CAS:
    <p>Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).</p>
    Formula:C18H21F2N7O
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:389.4
  • JAK-IN-5

    CAS:
    <p>JAK-IN-5 is a JAK inhibitor.</p>
    Formula:C27H31FN6O
    Purity:98.1% - 99.37%
    Color and Shape:Solid
    Molecular weight:474.57
  • MRK-560

    CAS:
    <p>MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.</p>
    Formula:C19H17ClF5NO4S2
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:517.92
  • JAK2-IN-4

    CAS:
    <p>JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.</p>
    Formula:C23H27N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:469.56
  • Casein Kinase II Inhibitor IV

    CAS:
    <p>Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.</p>
    Formula:C24H23N5O3
    Purity:99.65% - 99.75%
    Color and Shape:Solid
    Molecular weight:429.47
  • Nezulcitinib

    CAS:
    <p>Nezulcitinib (TD-0903) is an inhaled pan-JAK inhibitor targeting COVID-19-related acute lung injury.</p>
    Formula:C30H37N7O2
    Color and Shape:Solid
    Molecular weight:527.66
  • ABBV-712

    CAS:
    <p>ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 μM, and is implicated in the regulation of autoimmune diseases</p>
    Formula:C24H28N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:452.5
  • SWTX-143

    CAS:
    <p>SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptional</p>
    Formula:C19H18F3N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:361.36
  • DT-6

    CAS:
    <p>DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing</p>
    Formula:C89H130N20O29S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2008.23
  • JAK-IN-1

    CAS:
    <p>JAK-IN-1 shows improved selectivity for JAK3 over JAK1. JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively.</p>
    Formula:C20H24N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:380.44
  • STAT3-IN-20

    CAS:
    <p>STAT3-IN-20 (Compound 40), with an IC50 of 0.65 μM, is a selective inhibitor targeting the SH2 domain of STAT3, thereby impeding its phosphorylation, nuclear</p>
    Formula:C30H27F4N7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:593.64
  • STAT6-IN-2

    CAS:
    <p>STAT6-IN-2(R)-84 is a STAT6 inhibitor that inhibits the secretion of eotaxin-3 and the tyrosine phosphorylation of STAT6.</p>
    Formula:C28H31N5O2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:469.58
  • GNE-7883

    CAS:
    <p>GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.</p>
    Formula:C28H29FN6O2
    Purity:97.61%
    Color and Shape:Solid
    Molecular weight:500.57
  • H-1152 dihydrochloride

    CAS:
    <p>H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.</p>
    Formula:C16H23Cl2N3O2S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:392.34
  • ROCK-IN-1

    CAS:
    <p>ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurological</p>
    Formula:C20H18FN3O
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:335.37
  • Gossypolone

    CAS:
    <p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>
    Formula:C30H26O10
    Purity:96.66%
    Color and Shape:Solid
    Molecular weight:546.52