Stem Cells
Stem cell inhibitors are compounds that specifically target stem cells and their signaling pathways, affecting their ability to self-renew and differentiate. These inhibitors are crucial in research focused on controlling stem cell behavior, understanding developmental processes, and developing therapies for diseases like cancer, where stem cells are thought to play a key role. At CymitQuimica, we offer a variety of stem cell inhibitors to support your research in regenerative medicine, developmental biology, and oncology.
Found 234 products of "Stem Cells"
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BMP signaling agonist sb4
CAS:BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)Formula:C14H10BrNOSPurity:99.48% - 99.805%Color and Shape:SolidMolecular weight:320.2Ref: TM-T7799
5mg44.00€10mg57.00€25mg94.00€50mg119.00€100mg177.00€200mg268.00€500mg465.00€1mL*10mM (DMSO)48.00€BMS986260
CAS:BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).Formula:C18H12ClFN6OPurity:97.67%Color and Shape:SolidMolecular weight:382.78ZINC00881524
CAS:ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.
Formula:C21H20N2O3SPurity:99.48%Color and Shape:SolidMolecular weight:380.46Adavivint
CAS:Adavivint (Adavivint (SM04690)) (SM04690) is a Wnt pathway inhibitor.
Formula:C29H24FN7OPurity:98.27% - 98.6%Color and Shape:SolidMolecular weight:505.55Porcn-IN-1
CAS:Porcn-IN-1 (Porcupine-IN-1) is an effective porcupine inhibitor (IC50: 0.5±0.2 nM).Formula:C25H19FN4OPurity:99.15%Color and Shape:SolidMolecular weight:410.44BIO-013077-01
CAS:BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.Formula:C17H13N5Purity:99.87%Color and Shape:SolidMolecular weight:287.32Ref: TM-T8330
1mg50.00€5mg92.00€10mg140.00€25mg273.00€50mg393.00€100mg557.00€200mg753.00€1mL*10mM (DMSO)138.00€IWP-O1
CAS:IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.Formula:C26H20N6OPurity:99.12%Color and Shape:SolidMolecular weight:432.48Ref: TM-T5342
2mg39.00€5mg64.00€10mg101.00€25mg163.00€50mg226.00€100mg320.00€200mg459.00€1mL*10mM (DMSO)70.00€Tegatrabetan
CAS:Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.Formula:C28H36N4O6S2Purity:98.01% - 99.18%Color and Shape:SolidMolecular weight:588.74Ref: TM-T5642
1mg40.00€2mg52.00€5mg85.00€10mg124.00€25mg210.00€50mg334.00€100mg565.00€1mL*10mM (DMSO)96.00€SRI-011381 hydrochloride
CAS:SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.Formula:C20H32ClN3OPurity:99.32% - 99.41%Color and Shape:SolidMolecular weight:365.94Ref: TM-T5129
1mg34.00€2mg44.00€5mg66.00€10mg105.00€25mg215.00€50mg334.00€100mg497.00€200mg755.00€1mL*10mM (DMSO)73.00€AZD1080
CAS:AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.Formula:C19H18N4O2Purity:97.72% - 99.75%Color and Shape:SolidMolecular weight:334.37Ref: TM-T1741
1mg43.00€2mg56.00€5mg85.00€10mg124.00€25mg219.00€50mg350.00€100mg429.00€1mL*10mM (DMSO)63.00€IQ 1
CAS:IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions.
Formula:C21H22N4O2Purity:98.57% - ≥95%Color and Shape:SolidMolecular weight:362.42ITD-1
CAS:ITD-1 is a potent and highly selective TGFβ pathway inhibitor.Formula:C27H29NO3Purity:99.89% - >99.99%Color and Shape:SolidMolecular weight:415.52β-catenin-IN-2
CAS:β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.Formula:C15H14FN3Purity:99.93%Color and Shape:SolidMolecular weight:255.29Ref: TM-T9696
1mg96.00€5mg227.00€10mg359.00€25mg607.00€50mg868.00€100mg1,169.00€500mg2,365.00€1mL*10mM (DMSO)264.00€Afuresertib hydrochloride
CAS:Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
Formula:C18H18Cl3FN4OSPurity:99.96%Color and Shape:SolidMolecular weight:463.8Galunisertib
CAS:Galunisertib (LY2157299) is a selective TGF-β receptor type I (TGF-βRI) inhibitor. Galunisertib has antitumor activity. Cost-effective and quality-assured.Formula:C22H19N5OPurity:97.09% - 99.98%Color and Shape:SolidMolecular weight:369.42Ref: TM-T2510
1g657.00€5mg46.00€10mg52.00€25mg84.00€50mg114.00€100mg178.00€200mg269.00€500mg442.00€1mL*10mM (DMSO)52.00€I3MT-3
CAS:I3MT-3 (HMPSNE) is a selective inhibitor of 3MST, targeting active site cysteine residues and permeating cell membranes.Formula:C17H14N2O2SPurity:99.76%Color and Shape:SolidMolecular weight:310.37exo-IWR-1
CAS:exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin
Formula:C25H19N3O3Purity:97.41%Color and Shape:SolidMolecular weight:409.44YO-01027
CAS:YO-01027 (DBZ) is a potent γ-secretase inhibitor.
Formula:C26H23F2N3O3Purity:97.21% - 99.58%Color and Shape:SolidMolecular weight:463.48Belumosudil
CAS:Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM).Formula:C26H24N6O2Purity:97.64% - 98.59%Color and Shape:SolidMolecular weight:452.51Ref: TM-T6867
2mg48.00€5mg73.00€10mg90.00€25mg166.00€50mg250.00€100mg376.00€500mg895.00€1mL*10mM (DMSO)79.00€GSK269962A
CAS:GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.Formula:C29H30N8O5Purity:99.14% - 99.71%Color and Shape:SolidMolecular weight:570.6IHR-1
CAS:IHR-1, a Smo inhibitor (IC50 7.6 nM), blocks Hedgehog pathway, not Wnt/Notch, and prevents Smo in primary cilium.Formula:C20H12Cl4N2O2Purity:97.02%Color and Shape:SolidMolecular weight:454.13Ref: TM-T24159
2mg33.00€5mg50.00€10mg80.00€25mg131.00€50mg193.00€100mg290.00€200mg416.00€1mL*10mM (DMSO)55.00€MRT-14
CAS:MRT-14 is a potent Smo antagonist and can be used in several types of cancers linked to abnormal Hh signaling studies.Formula:C24H24N4O5Purity:99.54%Color and Shape:SolidMolecular weight:448.47Lats-IN-1
CAS:Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.Formula:C18H14N4OSPurity:97.54% - 99.79%Color and Shape:SolidMolecular weight:334.39Ref: TM-T9053
1mg52.00€2mg73.00€5mg105.00€10mg167.00€25mg309.00€50mg416.00€100mg592.00€200mg842.00€1mL*10mM (DMSO)118.00€LY3200882
CAS:LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).Formula:C24H29N5O3Purity:99.46% - 99.63%Color and Shape:SolidMolecular weight:435.52XMU-MP-1
CAS:XMU-MP-1 is a reversible and selective MST1/2 kinase inhibitor, IC50 values for MST1 and MST2 are 71.1 nM and 38.1 nM, respectively. High-Quality, Low-Cost!Formula:C17H16N6O3S2Purity:99.68% - 99.86%Color and Shape:SolidMolecular weight:416.48Ref: TM-T4212
1mg52.00€2mg79.00€5mg97.00€10mg153.00€25mg305.00€50mg512.00€100mg663.00€1mL*10mM (DMSO)95.00€Fosciclopirox
CAS:Fosciclopirox (CPX-POM), the phosphoryloxymethyl ester of CPX (Ciclopirox Prodrug, CPX-POM), selectively delivers the active metabolite, CPX, to the entireFormula:C13H20NO6PPurity:99.83%Color and Shape:SolidMolecular weight:317.27Ref: TM-T9422
2mg35.00€5mg52.00€10mg90.00€25mg170.00€50mg259.00€100mg383.00€200mg545.00€1mL*10mM (DMSO)58.00€AR-A014418
CAS:AR-A014418 (GSK 3β inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor.Formula:C12H12N4O4SPurity:>99.99% - ≥95%Color and Shape:SolidMolecular weight:308.31SRI-011381
CAS:SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.Formula:C20H31N3OPurity:98.64%Color and Shape:SolidMolecular weight:329.48SB 216763
CAS:SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).Formula:C19H12Cl2N2O2Purity:98.9% - 99.13%Color and Shape:SolidMolecular weight:371.22Ref: TM-T3077
2mg39.00€5mg52.00€10mg79.00€25mg131.00€50mg197.00€100mg334.00€500mg803.00€1mL*10mM (DMSO)52.00€PF-5274857
CAS:PF-5274857: selective hedgehog pathway inhibitor (IC50: 5.8 nM, Ki: 4.6 nM), treats brain tumors, crosses blood-brain barrier, orally stable.Formula:C20H25ClN4O3SPurity:98.53%Color and Shape:SolidMolecular weight:436.96MYF-01-37
CAS:MYF-01-37 (1-[3-Methyl-3-[3-(trifluoromethyl)anilino]pyrrolidin-1-yl]prop-2-en-1-one) is a novel covalent TEAD inhibitor.Formula:C15H17F3N2OPurity:99.46% - 99.5%Color and Shape:SolidMolecular weight:298.3Ref: TM-T22372
2mg38.00€5mg57.00€10mg90.00€25mg166.00€50mg281.00€100mg421.00€500mg888.00€1mL*10mM (DMSO)63.00€SD-208
CAS:SD-208 (ALK5 Inhibitor V), a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-βRII.Formula:C17H10ClFN6Purity:98.72% - 99.65%Color and Shape:SolidMolecular weight:352.75VP3.15 dihydrobromide
CAS:VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.Formula:C20H24Br2N4OSPurity:99.67% - ≥95%Color and Shape:SolidMolecular weight:528.3LGK974
CAS:LGK974 (NVP-LGK974) is a selective PORCN inhibitor that blocks Wnt signaling, used in metastatic colorectal and head/neck cancer trials. IC50: 0.4 nM.Formula:C23H20N6OPurity:98.8% - >99.99%Color and Shape:SolidMolecular weight:396.44Ref: TM-T2618
1mg46.00€2mg62.00€5mg90.00€10mg156.00€25mg288.00€50mg515.00€100mg737.00€1mL*10mM (DMSO)90.00€SJ000291942
CAS:SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.Formula:C16H15FN2O4Purity:99.66%Color and Shape:SolidMolecular weight:318.3Ref: TM-T4662
1mg34.00€2mg44.00€5mg63.00€10mg100.00€25mg205.00€50mg349.00€100mg557.00€200mg790.00€1mL*10mM (DMSO)71.00€Indirubin-3′-oxime
CAS:Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.
Formula:C16H11N3O2Purity:98.34%Color and Shape:SolidMolecular weight:277.28RKI1313
CAS:RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasionFormula:C17H16N4O2SPurity:99.53% - ≥95%Color and Shape:SolidMolecular weight:340.4Ref: TM-T2011
1mg70.00€5mg142.00€10mg207.00€25mg369.00€50mg540.00€100mg772.00€500µg49.00€1mL*10mM (DMSO)160.00€LSKL, Inhibitor of Thrombospondin TSP-1 2TFA
LSKL, Inhibitor of Thrombospondin TSP-1 acetate is activation of TGF-β .Formula:C25H44F6N6O9Purity:99.75%Color and Shape:SolidMolecular weight:686.64Ref: TM-T7676
2mg42.00€5mg54.00€10mg84.00€25mg138.00€50mg207.00€100mg316.00€200mg442.00€1mL*10mM (DMSO)93.00€Kartogenin
CAS:Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.Formula:C20H15NO3Purity:96.25% - 97.79%Color and Shape:SolidMolecular weight:317.34TBB
CAS:TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).
Formula:C6HBr4N3Purity:98.51% - 99.45%Color and Shape:Off-White SolidMolecular weight:434.71BML-284
CAS:BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.Formula:C19H18N4O3Purity:99.91% - 99.921%Color and Shape:SolidMolecular weight:350.37Ref: TM-T3144
5mg60.00€10mg88.00€25mg140.00€50mg253.00€100mg427.00€200mg615.00€500mg938.00€1mL*10mM (DMSO)66.00€IWP L6
CAS:IWP L6 (Porcn Inhibitor III) is an extremely effective Porcn inhibitor (EC50: 0.5 nM).
Formula:C25H20N4O2S2Purity:99.51% - >99.99%Color and Shape:SolidMolecular weight:472.58PF-4800567
CAS:PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.Formula:C17H18ClN5O2Purity:99.74% - 99.76%Color and Shape:SolidMolecular weight:359.81PRI-724
CAS:PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.
Formula:C33H35N6O7PPurity:98.25% - 99.11%Color and Shape:SoildMolecular weight:658.64EasyStep Human Cys-C(CystatinC) ELISA Kit
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Cys-C, and the Human Cys-C standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human Cys-C. After TMB substrate solution is added, only those wells that contain Human Cys-C and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human Cys-C in the samples is then determined by comparing the OD of the samples to the standard curve.Color and Shape:Colourless TransparentliquidVT107
CAS:VT107 is a potent pan-TEAD autopalmitoylation inhibitor. VT-107 can be used in cancer therapy research.Cost-effective and quality-assured.Formula:C25H20F3N3OPurity:99.72% - 99.92%Color and Shape:SolidMolecular weight:435.44Ref: TM-T35545
1mg130.00€5mg314.00€10mg477.00€25mg768.00€50mg1,045.00€100mg1,406.00€200mg1,882.00€1mL*10mM (DMSO)343.00€RO7185876
CAS:RO7185876 is a selective gamma secretase modulator, which can be used in the study of Alzheimer's disease.Formula:C25H28F3N7Purity:99.50%Color and Shape:SolidMolecular weight:483.532CHIR 98024
CAS:CHIR 98024: strong GSK-3α/β blocker, IC50 0.65/0.58 nM, selective over Cdc2/ERK2.Formula:C20H17Cl2N9O2Purity:99.45%Color and Shape:SolidMolecular weight:486.31Ref: TM-T3074
1mg44.00€2mg55.00€5mg96.00€10mg153.00€25mg298.00€50mg487.00€100mg705.00€1mL*10mM (DMSO)97.00€YAP/TAZ inhibitor-2
CAS:Potent oral TEAD-YAP/TAZ inhibitor-2 with 3 nM EC50; exhibits anti-proliferative and antitumor effects.Formula:C19H14F4N4OPurity:98.65%Color and Shape:SoildMolecular weight:390.33Ref: TM-T60218
1mg87.00€2mg113.00€5mg177.00€10mg281.00€25mg475.00€50mg687.00€100mg964.00€500mg1,918.00€1mL*10mM (DMSO)197.00€Ginisortamab
CAS:Ginisortamab (UCB6114) is a fully humanized monoclonal antibody targeting Gremlin-1, IC50=8.2 nM and 9 nM against human and mouse Gremlin-1, respectively.Purity:95% - 96.0% (SDS-PAGE); 97.0% (SEC-HPLC)Color and Shape:LiquidMolecular weight:147.55 kDaTrevogrumab
CAS:Trevogrumab is a human monoclonal antibody that inhibits myostatin (GDF8) to promote muscle growth, and is under research for treating age-related muscle loss (sarcopenia).Purity:95% - 97.6% (SDS-PAGE); 95.9% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.02 kDaTEAD-IN-6
CAS:TEAD-IN-6 (Example 11-1) is a TEAD modulator that inhibits the YAP1/TAZ-TEAD interaction, and has applications in cancer research [1].Formula:C19H17F3N4O3SPurity:98%Color and Shape:SolidMolecular weight:438.42VT103
CAS:VT103, an oral TEAD1 palmitoylation inhibitor, shows promise against various cancers by disrupting YAP/TAZ-TEAD interactions.Formula:C18H17F3N4O2SPurity:99.58%Color and Shape:SolidMolecular weight:410.41Ref: TM-T62077
1mg112.00€5mg268.00€10mg424.00€25mg735.00€50mg1,071.00€100mg1,549.00€200mg2,097.00€1mL*10mM (DMSO)295.00€JAK3/BTK-IN-2
CAS:JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.
Formula:C25H32N8O2Purity:99.64% - 99.87%Color and Shape:SolidMolecular weight:476.57Aβ42-IN-2
CAS:Aβ42-IN-2 is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42. Aβ42-IN-2 can be used for the Alzheimer's disease research[1].Formula:C24H26N6O2Purity:98.09% - 99.87%Color and Shape:SolidMolecular weight:430.5Ref: TM-T9641
1mg42.00€5mg94.00€10mg134.00€25mg215.00€50mg304.00€100mg420.00€200mg582.00€1mL*10mM (DMSO)93.00€TEAD-IN-2
CAS:TEAD-IN-2 is a potent and bifunctional TEAD inhibitor to induce TEAD protein degradation via the ubiquitination pathway, with anticancer potential.Formula:C16H18BrF3N2OColor and Shape:SolidMolecular weight:391.23CJJ300
CAS:CJJ300 is a TGF-β inhibitor disrupting TGF-β-TβR complex formation, with an IC50 of 5.3 μM, and halts cell migration.Formula:C30H33N3Purity:99.51%Color and Shape:SolidMolecular weight:435.6Ref: TM-T62483
2mg35.00€5mg51.00€10mg90.00€25mg164.00€50mg259.00€100mg393.00€200mg552.00€1mL*10mM (DMSO)57.00€CAY10746
CAS:CAY10746 selectively inhibits ROCK I/II with IC50s: 0.014/0.003 μM, useful for diabetic retinopathy research.Formula:C26H23N3O5Purity:99.71%Color and Shape:SolidMolecular weight:457.48Ref: TM-T36196
2mg35.00€5mg57.00€10mg90.00€25mg182.00€50mg274.00€100mg434.00€200mg582.00€1mL*10mM (DMSO)57.00€BRD0209
CAS:BRD0209 is a highly selective and potent GSK3 inhibitor.
Formula:C22H25N3OPurity:99.92%Color and Shape:SolidMolecular weight:347.45AF-2112
AF-2112, a TEAD inhibitor derived from Flufenamic acid, significantly diminishes the expression of CTGF, Cyr61, Axl, and NF2.
Formula:C21H18FNO3Purity:98%Color and Shape:SolidMolecular weight:351.37Chromenone 1
CAS:Chromenone 1 is a potent potentiator of osteogenic bone morphogenetic protein (BMP).Formula:C18H10F3N3O2Purity:99.83% - 99.93%Color and Shape:SolidMolecular weight:357.29Ref: TM-T61301
1mg52.00€5mg111.00€10mg162.00€25mg235.00€50mg330.00€100mg452.00€200mg607.00€1mL*10mM (DMSO)113.00€JA310
CAS:JA310 is a highly selective inhibitor of the MST3 kinase, demonstrating significant cellular potency with an EC50 value of 106 nM [1].Formula:C17H19N7OColor and Shape:SolidMolecular weight:337.38(Rac)-SIS3 free base
CAS:SIS3 free base is a potent and selective Smad3 phosphorylation inhibitor. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1.Formula:C28H27N3O3Purity:98%Color and Shape:SolidMolecular weight:453.53TGFβRI-IN-1
CAS:TGFβRI-IN-1 is an oral active and selective inhibitor of TGFβ receptor type I (TGFβRI) kinase(IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII,Formula:C20H14D3N5O2Purity:98%Color and Shape:SolidMolecular weight:362.4Wnt pathway activator 2
CAS:Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.Formula:C17H15NO4Purity:99.41%Color and Shape:SolidMolecular weight:297.31Ref: TM-T13345
1mg52.00€5mg100.00€10mg160.00€25mg329.00€50mg533.00€100mg770.00€200mg1,035.00€1mL*10mM (DMSO)111.00€GSK-3β inhibitor 12
CAS:GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.GSK-3βFormula:C14H13N3OSPurity:98.58%Color and Shape:SolidMolecular weight:271.34MSC-4106
CAS:MSC-4106, an oral YAP/TAZ-TEAD inhibitor, blocks TEAD1/3 auto-palmitoylation and suppresses NCI-H226 tumors.
Formula:C18H12F3N3O2Purity:99.89%Color and Shape:SoildMolecular weight:359.3XL413 xHCl
CAS:BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215
Formula:C14H12ClN3O2·xHClPurity:99.37% - 99.67%Color and Shape:SolidMolecular weight:326.18IHMT-MST1-58
CAS:IHMT-MST1-58 is a STE20-like protein 1 kinase (MST1) inhibitor (IC50:23 nM) with high efficiency, selectivity and oral activity.
Formula:C21H22N6O3SPurity:98.31% - 99.92%Color and Shape:SolidMolecular weight:438.5BIP-135
CAS:BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor.
Formula:C21H13BrN2O3Purity:99.93%Color and Shape:SolidMolecular weight:421.24GSK-3β inhibitor 2
CAS:GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) is a BBB-crossing and selective inhibitor of GSK-3β (IC50
Formula:C14H14N4O3SPurity:99.08%Color and Shape:SolidMolecular weight:318.35ABC1183
CAS:ABC1183, an oral diaminothiazole, inhibits GSK3α/β, CDK9, hinders cancer cell growth, induces G2/M arrest, and modulates phosphorylation.
Formula:C18H14N4OSPurity:98.92%Color and Shape:SolidMolecular weight:334.39LEQ506
CAS:LEQ506 is a Smo inhibitor with IC50s of 2 nM and 4 nM for hSmo and mSmo, respectively.Formula:C25H32N6OPurity:99.76%Color and Shape:SolidMolecular weight:432.56Ref: TM-T11838
1mg64.00€5mg145.00€10mg210.00€25mg338.00€50mg455.00€100mg610.00€200mg823.00€1mL*10mM (DMSO)160.00€CID-5056270
CAS:CID-5056270 has anticancer activity and can inhibit lung cancer, anal cancer, bladder cancer, cervical cancer, vulvar cancer, penile cancer, Burkitt's lymphoma
Formula:C17H13N3O3SPurity:99.6%Color and Shape:SolidMolecular weight:339.37GSK-3 Inhibitor XIII
CAS:GSK-3 InhibitorXIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.Formula:C18H15N5Purity:99.85% - 99.86%Color and Shape:SolidMolecular weight:301.35Ref: TM-T78578
1mg106.00€5mg243.00€10mg437.00€25mg934.00€50mg1,283.00€100mg1,730.00€200mg2,337.00€1mL*10mM (DMSO)251.00€GSK-3β inhibitor 11
CAS:GSK-3β inhibitor 11 (compound 21) is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β) with an inhibitory concentration (IC50) of 10.02 μM.
Formula:C20H15N3O4SPurity:97.33%Color and Shape:SolidMolecular weight:393.42SJ000063181
CAS:SJ000063181 activates BMP signaling (EC50 ≤1μM), usable as probe in zebrafish embryos.
Formula:C14H14ClFN2O2Purity:99.94%Color and Shape:SolidMolecular weight:296.72FzM1
CAS:FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)Formula:C21H16N2O2SPurity:99.37% - 99.89%Color and Shape:SolidMolecular weight:360.43Ref: TM-T24076
1mg42.00€5mg64.00€10mg99.00€25mg188.00€50mg328.00€100mg528.00€500mg1,130.00€1mL*10mM (DMSO)62.00€TT-10
CAS:TT-10 (TAZ-K) activates YAP-TEAD; useful in heart disease with cardiomyocyte loss research.
Formula:C11H10FN3OS2Purity:99.29%Color and Shape:SolidMolecular weight:283.35JAK1-IN-8
CAS:JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
Formula:C22H23FN4O3SPurity:98.4%Color and Shape:SolidMolecular weight:442.51LM-41
CAS:LM-41 is a TEAD binding agent with potential anticancer activity for the study of breast cancer.Formula:C19H14FNO2Purity:99.73%Color and Shape:SolidMolecular weight:307.32SWTX-143
CAS:SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptionalFormula:C19H18F3N3OPurity:98%Color and Shape:SolidMolecular weight:361.36ABBV-712
CAS:ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 μM, and is implicated in the regulation of autoimmune diseases
Formula:C24H28N4O5Purity:98%Color and Shape:SolidMolecular weight:452.5ML115
CAS:ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.Formula:C15H15ClN2O4Purity:99.97%Color and Shape:SolidMolecular weight:322.74Ref: TM-T35544
1mg95.00€5mg227.00€10mg359.00€25mg630.00€50mg882.00€100mg1,188.00€200mg1,596.00€500mg2,357.00€1mL*10mM (DMSO)251.00€TGFβ-IN-5
CAS:TGFβ-IN-5 (WAY-641966) is a potent TGFβ inhibitor with anti-prion activity for the study of fibroproliferative diseases associated with TGF-β signaling.Formula:C20H16N4Purity:99.29% - 99.62%Color and Shape:SolidMolecular weight:312.37ROCK2-IN-6 hydrochloride
CAS:ROCK2-IN-6 hydrochloride (Comp A)为一种选择性ROCK2抑制剂，适用于研究ROCK介导的疾病、自身免疫性病症与炎症。Formula:C26H22ClF2N7OPurity:98%Color and Shape:SolidMolecular weight:521.95DT-6
CAS:DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing
Formula:C89H130N20O29S2Purity:98%Color and Shape:SolidMolecular weight:2008.23TM2 TEAD inhibitor
CAS:TM2 TEAD inhibitor, a robust and reversible inhibitor of the TEA domain transcription factor, presents dual inhibitory concentrations (IC50) of 38 nM for TEAD4Formula:C26H33N3O3Purity:99.91%Color and Shape:SolidMolecular weight:435.57Stafib-2
CAS:Stafib-2 is a potent and selective inhibitor of the transcription factor STAT5b.Stafib-2 inhibits STAT5b and STAT5a with IC50 values of 82 nM and 1.7 μM,
Formula:C28H26N2O12P2Purity:98.48%Color and Shape:SolidMolecular weight:644.463,7-DMF
CAS:3,7-Dimethylfumarate (3,7-DMF) serves as an oral inhibitor of transforming growth factor-beta 1 (TGF-β1)-mediated hepatic stellate cell (HSC) activation.Formula:C17H14O4Purity:98%Color and Shape:SolidMolecular weight:282.29BRD5648
CAS:BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705.Formula:C20H23N3OPurity:99.89%Color and Shape:SolidMolecular weight:321.42Myristoyl tetrapeptide-12
CAS:Myristoyl Tetrapeptide-12 activates SMAD2 and facilitates the association of SMAD3 with DNA, promoting eyelash hair growth [1] [2].Formula:C32H63N7O5Purity:98%Color and Shape:SolidMolecular weight:625.89TP0427736
CAS:TP0427736: ALK5 inhibitor, IC50=2.72 nM, 300x > ALK3 selectivity; counters TGF-β in human cells, extends anagen in mice.Formula:C14H10N4S2Purity:97.26%Color and Shape:SolidMolecular weight:298.39YAP-TEAD-IN-2
CAS:YAP-TEAD-IN-2 (compound 6) serves as a potent inhibitor of the YAP-TEAD protein-protein interaction (PPI), demonstrating an inhibitory concentration 50 (IC50)Formula:C25H24ClFN2O4Purity:98%Color and Shape:SolidMolecular weight:470.92ROCK-IN-1
CAS:ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurologicalFormula:C20H18FN3OPurity:>99.99%Color and Shape:SolidMolecular weight:335.37GNE-7883
CAS:GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.Formula:C28H29FN6O2Purity:97.61%Color and Shape:SolidMolecular weight:500.57Ref: TM-T78558
1mg116.00€5mg283.00€10mg455.00€25mg747.00€50mg1,026.00€100mg1,444.00€200mg1,882.00€1mL*10mM (DMSO)310.00€YAP/TAZ inhibitor-3
CAS:YAP/TAZ inhibitor-3 (Compound 24) is a YAP/TAZ inhibitor applicable for relevant research within the life sciences field.Formula:C21H18F3NO3Purity:99.63%Color and Shape:SolidMolecular weight:389.37Ref: TM-T87651
1mg90.00€5mg215.00€10mg344.00€25mg695.00€50mg1,108.00€100mg1,791.00€200mg2,412.00€1mL*10mM (DMSO)236.00€Casein kinase 1δ-IN-13
CAS:Casein kinase1δ-IN-13 (compound 401) is an inhibitor of Casein kinase1δ. It is utilized in the research of neurodegenerative diseases.Formula:C15H13N3O2SColor and Shape:SolidMolecular weight:299.35WZ-2-033
CAS:WZ-2-033 is a potent STAT3 inhibitor. It inhibits proliferation, colony survival, migration, and invasion of MDA-MB-231, HCC70, and MDA-MB231-4175 cells, with IC50 values of 0.7, 1.3, and 1.3 μM respectively.Formula:C25H18F3N3O4SColor and Shape:SolidMolecular weight:513.49Kartogenin sodium
CAS:Kartogenin (KGN) sodium acts as an inducer of chondrogenic tissue formation (EC 50: 100 nM). It promotes chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and modulating the CBFβ-RUNX1 transcriptional program. Additionally, Kartogenin sodium aids tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. It is extensively utilized in cell-free therapies for cartilage regeneration and protection, tendon-bone healing, wound healing, and limb development. The compound is also vital for cartilage repair, coordinating limb development, and osteoarthritis (OA) research [1] [2] [3] [4].Formula:C20H14NNaO3Color and Shape:SolidMolecular weight:339.32
