Tyrosine Kinase/Adaptors
Tyrosine kinase and adaptor inhibitors are compounds that target tyrosine kinases and their associated adaptor proteins, which play pivotal roles in cell signaling, growth, and differentiation. These inhibitors are essential tools in cancer research, as many tyrosine kinases are involved in the signaling pathways that drive tumor growth and metastasis. By inhibiting tyrosine kinases, these compounds can block critical signaling cascades, offering potential therapeutic strategies for various cancers and other diseases involving abnormal cell signaling. At CymitQuimica, we provide a comprehensive range of high-quality tyrosine kinase and adaptor inhibitors to support your research in oncology, molecular biology, and targeted therapy development.
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Subcategories of "Tyrosine Kinase/Adaptors"
ALK
CSF-1R
EGFR
Ephrin Receptor
FLT
Fibroblast Growth Factor Receptor (FGFR)
HER
Hck
IGF-1R
PDGFR
PYK2
Src
TAM Receptor
Tie-2
Trk receptor
Tyrosine Kinases
VEGFR
c-Fms
c-Kit
c-Met/HGFR
c-RET
Show 13 more subcategories
Products of "Tyrosine Kinase/Adaptors"
(±)-Norcantharidin
CAS:29745-04-8
(±)-Norcantharidin (Endothall anhydride) is a synthetic anticancer compound which is a dual inhibitor for c-Met …
Formula:
C8H8O4
Purity:
99.43% - ≥98%
Color and Shape:
Solid
Molecular weight:
168.15
Ref: TM-T5656
| 1g | 530.00 € | ||
| 5mg | 44.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 77.00 € | ||
| 50mg | 103.00 € | ||
| 100mg | 151.00 € | ||
| 500mg | 357.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.
Formula:
C19H25ClN8
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
400.91
Ref: TM-T2056L
| 1mg | 86.00 € | ||
| 5mg | 168.00 € | ||
| 10mg | 252.00 € | ||
| 25mg | 414.00 € | ||
| 50mg | 582.00 € | ||
| 100mg | 787.00 € | ||
| 200mg | 1,044.00 € | ||
| 1mL*10mM (DMSO) | 190.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EAI045
CAS:1942114-09-1
EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.
Formula:
C19H14FN3O3S
Purity:
99.36% - 99.73%
Color and Shape:
Solid
Molecular weight:
383.4
Ref: TM-T6824
| 5mg | 43.00 € | ||
| 10mg | 59.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 123.00 € | ||
| 100mg | 195.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NVP-BVU972
CAS:1185763-69-2
NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM.
Formula:
C20H16N6
Purity:
100% - 98.61%
Color and Shape:
Solid
Molecular weight:
340.38
Ref: TM-T2680
| 1mg | 47.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 291.00 € | ||
| 50mg | 414.00 € | ||
| 100mg | 584.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sakuranetin
CAS:2957-21-3
Sakuranetin, a flavanone phytoalexin from ultraviolet-irradiated rice leaves, it has antifungal, antimutagenic, anti-inflammatory and antioxidant …
Formula:
C16H14O5
Purity:
99% - 99.65%
Color and Shape:
Solid
Molecular weight:
286.28
Ref: TM-TN1126
| 1mg | 47.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 321.00 € | ||
| 100mg | 462.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SU4312
CAS:5812-07-7
SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced …
Formula:
C17H16N2O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
264.32
Ref: TM-T3570
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 241.00 € | ||
| 50mg | 375.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
S49076
CAS:1265965-22-7
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of …
Formula:
C22H22N4O4S
Purity:
95.35% - 97.4%
Color and Shape:
Solid
Molecular weight:
438.5
Ref: TM-T3274
| 1mg | 46.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 167.00 € | ||
| 50mg | 301.00 € | ||
| 100mg | 549.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BPR1J-097
CAS:1327167-19-0
BPR1J-097) is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It …
Formula:
C27H28N6O3S
Purity:
99.3%
Color and Shape:
Solid
Molecular weight:
516.61
Ref: TM-T2272
| 2mg | 54.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 377.00 € | ||
| 100mg | 544.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Peficitinib
CAS:944118-01-8
Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.
Formula:
C18H22N4O2
Purity:
98.67% - 99.4%
Color and Shape:
Solid
Molecular weight:
326.39
Ref: TM-T6933
| 2mg | 40.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 272.00 € | ||
| 100mg | 424.00 € | ||
| 200mg | 634.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Canertinib dihydrochloride
CAS:289499-45-2
Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential …
Formula:
C24H27Cl3FN5O3
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
558.86
Ref: TM-T2501
| 5mg | 38.00 € | ||
| 10mg | 52.00 € | ||
| 50mg | 74.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
DS-1205
CAS:1855860-24-0
DS-1205: AXL kinase inhibitor (IC50=1.3 nM), also targets MER, MET, TRKA (IC50s: 63, 104, 407 …
Formula:
C41H42FN5O7
Purity:
99.28%
Color and Shape:
Solid
Molecular weight:
735.8
Ref: TM-T9123
| 1mg | 104.00 € | ||
| 5mg | 252.00 € | ||
| 10mg | 367.00 € | ||
| 25mg | 683.00 € | ||
| 50mg | 913.00 € | ||
| 1mL*10mM (DMSO) | 281.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Toceranib Phosphate
CAS:874819-74-6
Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several …
Formula:
C22H28FN4O6P
Purity:
98%
Color and Shape:
Solid
Molecular weight:
494.45
Ref: TM-T7394
| 10mg | 48.00 € | ||
| 25mg | 73.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 107.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Chrysophanol
CAS:481-74-3
Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and …
Formula:
C15H10O4
Purity:
97.91% - 99.7%
Color and Shape:
Physical Description Golden Yellow Plates Or Brown Powder Melting Point 196°C
Molecular weight:
254.24
Ref: TM-T2995
| 50mg | 43.00 € | ||
| 100mg | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AG490
CAS:133550-30-8
AG490 inhibits EGFR (0.1 μM IC50), 135x >selective than ErbB2, blocks JAK2, spares Lyn, Lck, …
Formula:
C17H14N2O3
Purity:
98.6% - 99.7%
Color and Shape:
Yellow Solid
Molecular weight:
294.3
Ref: TM-T2600
| 10mg | 55.00 € | ||
| 25mg | 74.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 100.00 € | ||
| 200mg | 162.00 € | ||
| 500mg | 278.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Crenolanib
CAS:670220-88-9
Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and …
Formula:
C26H29N5O2
Purity:
97.45% - 99.28%
Color and Shape:
Solid
Molecular weight:
443.54
Ref: TM-T2677
| 2mg | 57.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 127.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 263.00 € | ||
| 100mg | 434.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SYR127063
CAS:871026-18-5
SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a …
Formula:
C23H20ClF3N4O3
Purity:
98.57%
Color and Shape:
Solid
Molecular weight:
492.88
Ref: TM-T34760
| 1mg | 128.00 € | ||
| 5mg | 281.00 € | ||
| 10mg | 423.00 € | ||
| 25mg | 694.00 € | ||
| 50mg | 978.00 € | ||
| 1mL*10mM (DMSO) | 352.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Capmatinib 2HCl
CAS:1197376-85-4
Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, …
Formula:
C23H19Cl2FN6O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
485.34
Ref: TM-T4260
| 1mg | 43.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 146.00 € | ||
| 50mg | 258.00 € | ||
| 100mg | 430.00 € | ||
| 500mg | 976.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD8931 diFuMaric acid
CAS:1196531-39-1
AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of …
Formula:
C31H33ClFN5O11
Purity:
99%
Color and Shape:
Solid
Molecular weight:
706.1
Ref: TM-T8751
| 1mg | 85.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 249.00 € | ||
| 25mg | 410.00 € | ||
| 50mg | 577.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € | ||
| 1mL*10mM (DMSO) | 247.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CP-724714
CAS:383432-38-0
CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against …
Formula:
C27H27N5O3
Purity:
97.10% - 98.82%
Color and Shape:
Solid
Molecular weight:
469.54
Ref: TM-T4014
| 1mg | 43.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 267.00 € | ||
| 50mg | 445.00 € | ||
| 100mg | 646.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZ7550
CAS:1421373-99-0
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
Formula:
C27H31N7O2
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
485.58
Ref: TM-T13564
| 1mg | 129.00 € | ||
| 5mg | 282.00 € | ||
| 10mg | 417.00 € | ||
| 25mg | 689.00 € | ||
| 50mg | 920.00 € | ||
| 100mg | 1,287.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
