VEGFR
VEGFR (Vascular Endothelial Growth Factor Receptor) inhibitors are compounds that block the signaling of VEGFR, a key receptor in the VEGF pathway, which is crucial for angiogenesis. VEGFR inhibitors prevent the formation of new blood vessels that supply nutrients and oxygen to tumors, thereby inhibiting tumor growth. These inhibitors are widely used in cancer therapy and research to study the mechanisms of angiogenesis and develop anti-cancer treatments. At CymitQuimica, we provide a comprehensive range of high-quality VEGFR inhibitors to support your research in oncology, vascular biology, and angiogenesis.
Found 239 products of "VEGFR"
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SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formula:C17H16N2O3Purity:98.91% - 99.64%Color and Shape:Yellow-Green SolidMolecular weight:296.32SKLB 610
CAS:SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively,
Formula:C21H16F3N3O3Purity:99.33% - 99.83%Color and Shape:SolidMolecular weight:415.37SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFormula:C17H15NO2Purity:99.46%Color and Shape:SolidMolecular weight:265.31Tivozanib
CAS:Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.Formula:C22H19ClN4O5Purity:98.08% - 99.67%Color and Shape:SolidMolecular weight:454.86Ref: TM-T2456
2mg38.00€5mg57.00€10mg79.00€25mg135.00€50mg226.00€100mg405.00€200mg597.00€1mL*10mM (DMSO)63.00€MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formula:C21H18N2OPurity:98.53%Color and Shape:SolidMolecular weight:314.38AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Formula:C24H25N5O4Purity:97.71% - 98.37%Color and Shape:SolidMolecular weight:447.49AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purity:98.48% - 99.96%Color and Shape:SolidMolecular weight:246.3Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purity:99.54% - 99.77%Color and Shape:SolidMolecular weight:482.51Ref: TM-T7104
5mg51.00€10mg79.00€25mg129.00€50mg213.00€100mg358.00€200mg535.00€500mg843.00€1mL*10mM (DMSO)57.00€AAL-993
CAS:AAL-993: VEGFR inhibitor; IC50: 130 nM (1), 23 nM (2), 18 nM (3); weak on other tyrosine kinases; antiangiogenic & antitumor.Formula:C20H16F3N3OPurity:99.65%Color and Shape:SolidMolecular weight:371.36Ref: TM-T21593
1mg43.00€5mg93.00€10mg138.00€25mg260.00€50mg409.00€100mg605.00€500mg1,288.00€1mL*10mM (DMSO)92.00€RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Formula:C24H16F6N6OPurity:99.56%Color and Shape:SolidMolecular weight:518.41Ref: TM-T6296
1mg44.00€2mg59.00€5mg93.00€10mg140.00€25mg253.00€50mg413.00€100mg605.00€1mL*10mM (DMSO)94.00€NVP-BAW2881
CAS:NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor with activity to inhibit chronic and acute skin inflammation.Formula:C22H15F3N4O2Purity:98.19% - 99.97%Color and Shape:SolidMolecular weight:424.38Ref: TM-T3641
1mg34.00€2mg48.00€5mg71.00€10mg109.00€25mg200.00€50mg324.00€100mg470.00€500mg1,054.00€1mL*10mM (DMSO)69.00€SU5205
CAS:SU5205 is a VEGFR2 inhibitor.
Formula:C15H10FNOPurity:99.62% - 99.67%Color and Shape:SolidMolecular weight:239.24Foretinib
CAS:Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR.Formula:C34H34F2N4O6Purity:98.07% - 99.68%Color and Shape:SolidMolecular weight:632.65Ref: TM-T3113
2mg39.00€5mg57.00€10mg79.00€25mg133.00€50mg207.00€100mg354.00€500mg848.00€1mL*10mM (DMSO)79.00€Vorolanib
CAS:Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.Formula:C23H26FN5O3Purity:97.35%Color and Shape:SolidMolecular weight:439.48Ref: TM-T8491
1mg101.00€2mg142.00€5mg215.00€10mg340.00€25mg583.00€50mg842.00€100mg1,144.00€200mg1,521.00€1mL*10mM (DMSO)236.00€Fruquintinib
CAS:Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-Formula:C21H19N3O5Purity:98.84% - 99.89%Color and Shape:SolidMolecular weight:393.39Ref: TM-T2656
2mg35.00€5mg52.00€10mg85.00€25mg117.00€50mg147.00€100mg250.00€500mg620.00€1mL*10mM (DMSO)58.00€Orantinib
CAS:Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:SolidMolecular weight:310.35AG-13958
CAS:AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.Formula:C26H22FN7OPurity:99.4%Color and Shape:SolidMolecular weight:467.5Ref: TM-T7493
1mg92.00€5mg250.00€10mg385.00€25mg620.00€50mg893.00€100mg1,189.00€1mL*10mM (DMSO)260.00€Motesanib
CAS:Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.Formula:C22H23N5OPurity:98% - 99.09%Color and Shape:SolidMolecular weight:373.45Ref: TM-T2288
5mg34.00€10mg49.00€25mg81.00€50mg114.00€100mg160.00€200mg230.00€500mg389.00€1mL*10mM (DMSO)39.00€KRN-633
CAS:KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.Formula:C20H21ClN4O4Purity:99.53% - 99.73%Color and Shape:SolidMolecular weight:416.86JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formula:C22H20BrN5O2Purity:99.41% - 99.97%Color and Shape:SolidMolecular weight:466.33Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54Cediranib
CAS:Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Formula:C25H27FN4O3Purity:97.21% - 99.94%Color and Shape:SolidMolecular weight:450.51Ref: TM-T2500
2mg39.00€5mg59.00€10mg87.00€25mg129.00€50mg168.00€100mg240.00€200mg439.00€500mg703.00€1mL*10mM (DMSO)65.00€SCR-1481B1
CAS:SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitorFormula:C32H40ClF2N6O13PPurity:98.07%Color and Shape:SolidMolecular weight:821.12Ref: TM-T5349
1mg35.00€2mg50.00€5mg74.00€10mg113.00€25mg200.00€50mg333.00€100mg495.00€1mL*10mM (DMSO)102.00€Oglufanide
CAS:Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).Formula:C16H19N3O5Purity:99.80%Color and Shape:SolidMolecular weight:333.34EOC317
CAS:EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).Formula:C27H26F5N7O3Purity:98.00% - 99.26%Color and Shape:SolidMolecular weight:591.53SU5208
CAS:SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).Formula:C13H9NOSPurity:99.62%Color and Shape:SolidMolecular weight:227.28Ref: TM-T22432
1mg46.00€5mg94.00€10mg148.00€25mg225.00€50mg310.00€100mg434.00€200mg583.00€1mL*10mM (DMSO)95.00€Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFormula:C21H18FN5OPurity:98% - 98.24%Color and Shape:SolidMolecular weight:375.4Ref: TM-T2514
5mg48.00€10mg80.00€25mg119.00€50mg178.00€100mg259.00€200mg477.00€500mg772.00€1mL*10mM (DMSO)50.00€GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formula:C21H23N7O2S·HClPurity:99.87%Color and Shape:SolidMolecular weight:473.98KI8751
CAS:KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.Formula:C24H18F3N3O4Purity:99.22% - 99.9%Color and Shape:SolidMolecular weight:469.41Ref: TM-T2446
2mg34.00€5mg50.00€10mg81.00€25mg147.00€50mg279.00€100mg447.00€200mg635.00€1mL*10mM (DMSO)52.00€Vatalanib dihydrochloride
CAS:Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.Formula:C20H15ClN4·2HClPurity:99.16%Color and Shape:White To Off-White Crystalline PowderMolecular weight:419.73Golvatinib
CAS:Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factorFormula:C33H37F2N7O4Purity:98.24% - ≥95%Color and Shape:SolidMolecular weight:633.69Ref: TM-T6517
1mgTo inquire2mg46.00€5mg66.00€10mg92.00€25mg149.00€50mg197.00€100mg350.00€1mL*10mM (DMSO)To inquireNingetinib Tosylate
CAS:Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formula:C38H37FN4O8SPurity:99.93%Color and Shape:SolidMolecular weight:728.79Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormula:C29H27F3N6OPurity:98% - 99.60%Color and Shape:SolidMolecular weight:532.56SU5214
CAS:SU5214 is a modulator of tyrosine kinase signal transduction.Formula:C16H13NO2Purity:99.45% - 99.55%Color and Shape:SolidMolecular weight:251.28UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.Formula:C19H25ClN8Purity:99.52%Color and Shape:SolidMolecular weight:400.91Ref: TM-T2056L
1mg84.00€5mg168.00€10mg245.00€25mg404.00€50mg567.00€100mg767.00€200mg1,018.00€1mL*10mM (DMSO)185.00€Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Formula:C22H28FN4O6PPurity:98.56%Color and Shape:SolidMolecular weight:494.45Ramucirumab
CAS:Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.Formula:C285H434N74O88S2Purity:98.2% (SDS-PAGE); 99.2% (SEC-HPLC) - 99.20%Color and Shape:LiquidMolecular weight:143.77 kDaNingetinib
CAS:Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formula:C31H29FN4O5Purity:99.95% - 99.98%Color and Shape:SolidMolecular weight:556.58Orobol
CAS:Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.Formula:C15H10O6Purity:98% - 98%Color and Shape:SolidMolecular weight:286.24XL 999
CAS:Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）Formula:C26H28FN5OPurity:98.24% - 99.55%Color and Shape:SolidMolecular weight:445.53Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).
Formula:C28H24FN3O5Purity:99.68% - 99.88%Color and Shape:SolidMolecular weight:501.51BFH772
CAS:BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).Formula:C23H16F3N3O3Purity:97.71% - 99.89%Color and Shape:SolidMolecular weight:439.39Su1498
CAS:Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the VEGF receptor 2, having negligible activity at several other serine/threonine and tyrosine kinases.
Formula:C25H30N2O2Purity:99.54%Color and Shape:SolidMolecular weight:390.52Regorafenib Hydrochloride
CAS:Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.Formula:C21H16Cl2F4N4O3Purity:99.56%Color and Shape:SolidMolecular weight:519.28Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C24H25Cl2FN4O2Purity:97.89% - 98.66%Color and Shape:SolidMolecular weight:491.39NVP-ACC789
CAS:ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.
Formula:C21H17BrN4Purity:99.44% - 99.63%Color and Shape:SolidMolecular weight:405.29CZC-8004
CAS:CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formula:C17H16FN5Purity:99.29%Color and Shape:SolidMolecular weight:309.34Nintedanib
CAS:Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/Formula:C31H33N5O4Purity:98% - 99.92%Color and Shape:SolidMolecular weight:539.62Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Formula:C17H16O4Purity:99.87% - ≥95%Color and Shape:SolidMolecular weight:284.31
