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Ubiquitination

Ubiquitination

Ubiquitination inhibitors are compounds that interfere with the process of ubiquitination, where proteins are tagged with ubiquitin molecules for degradation by the proteasome. These inhibitors are critical for studying protein turnover, signal transduction, and the regulation of various cellular processes. Ubiquitination plays a key role in many diseases, including cancer, neurodegenerative disorders, and immune system dysfunction. By modulating ubiquitination, these inhibitors can provide insights into the mechanisms of disease and open up new avenues for therapeutic intervention. At CymitQuimica, we offer a wide selection of high-quality ubiquitination inhibitors to support your research in cell biology, proteomics, and drug discovery.

Subcategories of "Ubiquitination"

Found 107 products of "Ubiquitination"

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  • Cbl-b-IN-26

    CAS:
    <p>Cbl-b-IN-26 (Example A1) is an inhibitor of Cbl-b with a dissociation constant (Kd) of 34.6 nM. It is used in the research of chronic viral infections and cancer.</p>
    Formula:C21H19F3N6
    Color and Shape:Solid
    Molecular weight:412.41
  • USP7-797

    CAS:
    <p>USP7-797 is a selective non-covalent active site USP7 inhibitor, inhibiting USP7 and ubiquitin binding, with anti-tumor, oral and high efficiency properties.</p>
    Formula:C27H28ClN3O3S
    Purity:95.90%
    Color and Shape:Solid
    Molecular weight:510.05
  • USP7-IN-6

    CAS:
    <p>USP7-IN-6 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 6.8 nM).</p>
    Formula:C41H43N7O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:729.89
  • DCN1-UBC12-IN-4

    CAS:
    <p>DCN1-UBC12-IN-4 (compound 5p) acts as an inhibitor of DCN1-UBC12, exhibiting an IC50 value greater than 10000 nM and possesses antitumor activity.</p>
    Formula:C8H6ClN3S
    Color and Shape:Solid
    Molecular weight:211.67
  • USP15-IN-1

    CAS:
    <p>USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM).</p>
    Formula:C22H23N3O3
    Purity:99.509% - 99.81%
    Color and Shape:Solid
    Molecular weight:377.44
  • USP5-IN-1


    <p>USP5-IN-1, a powerful USP5 deubiquitinase inhibitor, selectively binds with 2.8 μM affinity, blocking USP5's di-ubiquitin cleavage.</p>
    Formula:C19H20ClN3O5S
    Purity:99.76%
    Color and Shape:Soild
    Molecular weight:437.9
  • Cbl-b-IN-3

    CAS:
    <p>Cbl-b-IN-3 is a potent inhibitor of casitas b lineage lymphoma proto-oncogene-b (Cbl-b) (ic50 &lt; 1 nM).Cost-effective and quality-assured.</p>
    Formula:C30H34F3N5O
    Purity:99%
    Color and Shape:Solid
    Molecular weight:537.62