Polycyclic Compounds

<p>4-Nitrobenzyl (4R,5R,6S)-3-[(diphenylphosphono)oxy]-6-[(R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylat e is a synthetic compound that is used as an alkalizer and impurity scavenger in the manufacture of pesticides and other organic chemicals. It has been shown to be a stereoselective herbicide with acetonitrile as its primary degradation product. The compound has also been found to be a potent inhibitor of the enzyme carbapenemase, which may lead to increased resistance to antibiotics such as monosodium salt of ertapenem.</p>

<p>Please enquire for more information about Ethyl 5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fraxin is a naturally occurring anticoagulant, which is derived from the bark of certain species of the Fraxinus tree. It functions by inhibiting thrombin and other key enzymes in the coagulation cascade, thus preventing the formation of blood clots. This mode of action makes it particularly valuable in research settings focused on cardiovascular diseases, as well as in the development of therapeutic agents targeting coagulopathies.</p>

<p>Quinoline 2,4-dicarboxylic acid (QDA) is a novel cytotoxic agent that targets cervical cancer cells. It inhibits the uptake of glucose and other nutrients by cervical cancer cells, leading to cell death through apoptosis. QDA also inhibits the expression of genes involved in cross-linking reactions, which are important for the structural integrity of proteins. This agent has been shown to inhibit the growth of aniline-induced breast cancer cells and glutamate-stimulated PC12 cells. QDA binds to DNA and forms covalent bonds with nucleotide bases, inhibiting DNA synthesis, as well as interfering with protein synthesis and cell division. The QDA mechanism is similar to that of benzoquinolines and estrone sulfate.</p>

<p>4,5,6-Trimethoxyindole is a chemical compound that is found in the plant Chinensis. This compound has been shown to have potent anticancer properties and can be used as a treatment for inflammatory diseases. 4,5,6-Trimethoxyindole has been shown to modulate the activity of some bacteria and it has been hypothesized that this may be due to its interaction with formylation. The acidic nature of 4,5,6-Trimethoxyindole makes it soluble in ethanol. It can also be synthesised from butyric acid and other chemicals.</p>

<p>3-Methylphenanthrene is a compound that inhibits the reductase activity of aromatic hydrocarbons. 3-Methylphenanthrene has been shown to inhibit both bacterial and mammalian reductases, with interactive effects on the enzyme's substrate molecule. It also shows an inhibitory effect on axonal growth, which may be due to its ability to reduce fatty acid uptake, as well as its ability to interact with the aromatic hydrocarbon uptake system. 3-Methylphenanthrene is easily detected by spectrometry analyses and can be used as a substrate molecule for bacterial enzymes.</p>

<p>5,6-Dichloroindole is a chemical compound that contains a functional group with acidic properties. The compound has been shown to inhibit the activity of bafilomycin A1, which is an inhibitor of vacuolar ATPase. This inhibition leads to an increase in intracellular phosphate levels and an accumulation of lysosomal membrane proteins. 5,6-Dichloroindole has also been found to inhibit bone resorption in gramine-fed rats. It also has anti-inflammatory effects and inhibits the growth of zoobotryon pinnatum cells and algal cells. 5,6-Dichloroindole can be used as a molecular descriptor for predicting the presence or absence of bryozoan species in a sample.</p>

<p>Indole-3-acetyl-L-valine (IAV) is a naturally occurring amino acid that binds to the surface glycoprotein of wild-type viruses. It inhibits viral replication by inhibiting the production of basic proteins, which are necessary for viral life. IAV also has inhibitory properties against the toll-like receptor, which may be due to its ability to inhibit growth factor signaling. IAV has been shown to decrease the number of opportunistic fungal and bacterial infections in humans, with no adverse effects on human health. This drug has no effect on healthy cells and can be used as an adjuvant for the treatment of HIV and other viral infections.</p>

<p>Please enquire for more information about 13,4-diaza-5-(tert-butyl)-2-hydroxy-7-oxotricyclo[6.4.0.0&lt;2,6&gt;]dodeca-1(8),4,9,11-tetraene-3-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Oxypeucedanin is a furanocoumarin compound, which is derived from various plant sources, most notably those in the Apiaceae family such as Peucedanum and Angelica species. It functions primarily as a photoreactive agent, capable of interacting with DNA under ultraviolet (UV) light through a process called photoactivation. Upon UV exposure, it forms covalent bonds with DNA, leading to cross-linking that can disrupt cellular functions.</p>

<p>6-Fluoro-2-methylindole is a member of the group of aromatic ketones. It is an organic compound that can be synthetized from 2,6-dichloroindole and methyl iodide. There are two types of photodimerization reactions for 6-fluoro-2-methylindole: one is an aerobic reaction and the other is an anaerobic reaction. The mechanistic study of 6-fluoro-2-methylindole has been investigated using bond cleavage and transformation reactions. This organic compound reacts with amines to form polycycles with high yields. It also undergoes Diastereomeric Control in chemistry.</p>

<p>5-Methyl-3-piperidin-4-yl-1H-indole hydrochloride is a synthetic chemical that is used as a building block for the synthesis of other compounds. It is a versatile intermediate, having been shown to react with amines, alcohols, phenols, and thiols. 5-Methyl-3-piperidin-4-yl-1H-indole hydrochloride can be used in the manufacture of pharmaceuticals and agrochemicals. This compound has been found to be an effective reagent for the preparation of cyclic peptides and can be used as a building block for the synthesis of other compounds. When reacted with 2-(trimethylsilyl)ethanol, it produces a high quality complex compound.</p>

<p>1H-Indoline-3-carboxylic acid is a molecule with the chemical formula C8H6N2O2. It is an aromatic carboxylic acid and one of the three enantiopure isomers of indoline. 1H-Indoline-3-carboxylic acid has two tautomers, cis (cis) and trans (trans). The stereoisomer cis is found in nature, while trans can be synthesized. 1H-Indoline-3-carboxylic acid can be cleaved to form phenylacetic acid and benzoic acid in reactions catalyzed by acids at high temperatures. Kinetic studies have shown that 1H-indoline-3-carboxylic acid undergoes biotransformation to form methylbenzene, ethylbenzene, propylbenzene, butylbenzene, pentylbenzene and hexylbenzene.</p>

<p>3,4-Dihydro-2(1H)-quinolinone is a potent inhibitor of dopamine β-hydroxylase and is used as a model system to study the pharmacokinetic properties of carbostyril. It has been shown that 3,4-dihydro-2(1H)-quinolinone binds to the chloride ion in the active site of dopamine β-hydroxylase. This binding prevents the formation of a complex with the enzyme's substrate, which is required for catalysis. 3,4-Dihydro-2(1H)-quinolinone also interacts with the alkynyl group on dopamine and competitively inhibits its metabolism by monoamine oxidase (MAO).</p>

<p>Isoscopoletin is a naturally occurring coumarin derivative, which is typically sourced from various plants, including some medicinal herbs. This compound is found in a variety of plant species, where it plays a role in the plant's defense mechanisms against pathogens. It is known for its characteristic chemical structure that belongs to the coumarin family, which is widespread in the plant kingdom.</p>

<p>5-Methylindole-3-carboxaldehyde (5MI) is a β-unsaturated aldehydes that is used as an analyte in assays for the detection of α,β-unsaturated aldehydes. It has been shown to be effective in degranulation of cells and induces cellular degranulation. 5MI has also been shown to be an analog of other β-unsaturated aldehydes and acts competitively with these compounds.</p>

<p>6-Azaindole is a drug that inhibits the activity of the enzyme aromatase, which is responsible for the conversion of testosterone to estrogen. 6-Azaindole has shown potent inhibitory activity against cancer cells in vitro and in vivo. It also has an inhibitory effect on pain relief mechanisms at low doses, but not at high doses. The mechanism of action is complex and multifactorial; it may involve inhibition of proton transfer, receptor activity, and/or inhibition of nitrogen atoms. The synthesis of 6-azaindoles can be carried out using a variety of methods and starting materials, including asymmetric synthesis or reduction of an n-oxide moiety.</p>

<p>4-Imidazoleacetic acid HCl is a fluorescent probe that binds to the α1 subunit of the dinucleotide phosphate (NADH) oxidoreductase. It has been shown to inhibit mitochondrial functions, which may be due to its ability to inhibit the pentose phosphate pathway and reduce reactive oxygen species levels. 4-Imidazoleacetic acid HCl has also shown inhibitory properties against congestive heart failure by acting on the mitochondria and inhibiting energy metabolism. It can also be used as a chemical biology tool for studying protein interactions with NADH dehydrogenase. The x-ray crystal structures have revealed that 4-imidazoleacetic acid HCl binds to the active site of NADH oxidoreductase with an orientation that mimics a substrate molecule. This allows it to bind tightly and disrupt enzyme activity.</p>

<p>5,7-Dinitroindole-2-carboxylic acid is a versatile building block that has been used as a reagent in organic synthesis. It has also been shown to be an intermediate in the preparation of 5,7-dichloroindole and other complex compounds. This compound is a reaction component for the synthesis of many useful compounds, including research chemicals and speciality chemicals. 5,7-Dinitroindole-2-carboxylic acid is soluble in most solvents and can be purified by recrystallization or chromatography. The purity can be determined by elemental analysis or nuclear magnetic resonance spectroscopy.</p>

<p>5-Bromoisatoic anhydride is a potential anticancer agent that contains nitrogen atoms. It inhibits the growth of cancer cells by binding to the enzyme acetylcholine, which is involved in the production of growth factors. The compound also inhibits the production of malonic acid, which is a metabolic disorder. 5-Bromoisatoic anhydride forms stable complexes with malonic acid and does not cause any adverse effects on normal cells.</p>

<p>6-Bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one is a versatile building block that can be used in a variety of chemical reactions as an intermediate. It is also useful in the synthesis of a variety of compounds, such as pharmaceuticals and research chemicals. 6-Bromo-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one is an organic compound with a molecular formula of C8H5BrN4O. It has an mp of 152°C and decomposes to form nitrogen gas and carbon monoxide at higher temperatures.</p>

<p>8-Methoxy-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is a versatile building block that can be used as a reagent or speciality chemical. It has been used in research and development of pharmaceuticals and as a useful intermediate for the synthesis of other compounds. 8-Methoxy-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is an important reaction component for the synthesis of many types of compounds such as indoles, coumarins, and quinazolinones.</p>

<p>Daphnetin dimethyl ether is a synthetic chemical compound, which is a derivative of the naturally occurring coumarin scaffold. It is primarily sourced through chemical synthesis rather than extraction from natural compounds, allowing for precise control over purity and structural modifications that are otherwise challenging to achieve through natural means.</p>

<p>Impurity found in Primaquine diphosphate</p>

<p>1,1,3,3,4,4,4a,5,5,6,6,7,7,8,8,8a-Hexadecafluoro-2-(trifluoromethyl)decahydroisoquinoline is an organic solvent that has a very low boiling point and high volatility. It can be used in dry powder inhalers or as a component of hydrogel compositions for oxygen delivery to the lungs. The uptake of 1HF-2TFI into human colon carcinoma cells was found to be significantly higher than uptake by mammary carcinomas. This may be due to the difference in cell types and/or the phosphate group on the molecule. The binding constants of this molecule are also higher than those of other organic solvents such as acetone and ethanol. The results from a questionnaire study also indicated that 1HF-2TFI can be used for perfusion with oxygenated gas mixtures for</p>

<p>2,6-Diaminopurine is a nucleotide analogue that is synthesized from guanosine. It inhibits the enzyme ribonucleotide reductase and blocks the synthesis of DNA precursors, which are necessary for viral replication. 2,6-Diaminopurine has been shown to inhibit hiv infection in tissue culture and animal models by decreasing the levels of nucleotides in cells. This drug can be used as an anti-viral agent against HIV and other retroviruses. 2,6-Diaminopurine has also been shown to be effective against murine sarcoma virus. The compound binds to the enzyme ribonucleotide reductase, which is important for DNA synthesis, and prevents its activity by mimicking adenosine triphosphate (ATP). The binding of 2,6-diaminopurine to ATP results in a coordination geometry that causes a long hydrogen bond with one oxygen</p>

<p>Extensive research has been conducted on the antimicrobial activity of 6-fluoro-1-methyl-4-oxo-7-(1-piperazinyl)-4H-(1,3)thiazeto(3,2a)quinoline-3-carboxylic acid (FPMT). FPMT is a levorotatory compound that is rapidly metabolized by esterases to 6FMT, which is also active against bacteria. FPMT inhibits bacterial growth, but does not inhibit mammalian cell growth. The main mechanism of action for FPMT is probably through its ability to inhibit the synthesis of bacterial DNA and RNA. This drug has been shown to be effective against sinusitis caused by bacterial rhinosinusitis and urinary tract infections caused by Escherichia coli and Pseudomonas aeruginosa. FPMT can be used as an alternative to prulifloxacin for the treatment of these types of infections</p>

<p>2-Methyl-6-quinolinecarboxylic acid is a molecule with an affinity for aromatic rings. It has been shown through experiment that this molecule has a stable structure and can be transferred from one ring to another. 2-Methyl-6-quinolinecarboxylic acid has also been shown to have an affinity for aromatic rings in the range of 8.1 × 10 to 8.3 × 10 M−1, with an experimental affinity value of 1.2 × 10 M−1. This compound is known to interact with other molecules in a molecular docking process and can be optimized using parameters such as hydrogen bonding and van der Waals interactions.END&gt; END&gt;</p>

<p>3-Methyl-8-quinolinesulfonyl chloride (3MQSC) is a reaction product of 1,2,4-trioxane and thionyl chloride. 3MQSC is used as an intermediate in the production of l-citrulline from chloroacetic acid. It reacts with paraformaldehyde to form a solid phase synthesis catalyst. 3MQSC catalyzes the reaction between phosphorus pentachloride and chlorine to produce ethyl formate and hydrogen chloride gas. This process is industrialized for the production of ethyl formate, which is used for the manufacture of acetic acid, chlorinated solvents, polymers, and plastics. The high yield of this process makes it one of the most popular routes for producing ethyl formate. Catalysis by 3MQSC can be achieved at low temperature and pressure due to its resistance to heat and low boiling point.</p>

<p>5-Methoxypsoralen is a light-activated compound, which is a naturally derived organic substance found in certain plants, particularly from the Apiaceae family. This compound functions as a furocoumarin that interacts with DNA through photoactivation, forming cross-links upon exposure to ultraviolet A (UVA) light. These cross-links disrupt DNA replication, ultimately inhibiting cell proliferation.</p>

<p>L-5-Methyltetrahydrofolate calcium is also known as calcium levomefolate; N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, calcium salt; and L-5-MTHF. L-5-Methyltetrahydrofolate calcium is the calcium salt of L-5-methyltetrahydrofolic acid, and a member of the folate group of vitamins (Vitamin B9). It is the coenzymated and most active form of folic acid, which performs many vital cellular functions, including DNA reproduction, cysteine cycle and homocysteine regulation. L-5-Methyltetrahydrofolate calcium is used as in dietary supplements and has been proposed for treatment of cardiovascular disease.</p>

<p>3-Indolemethanol is a chemical compound that is used for chemiluminescent reaction. It can be used as an experimental model for studying the effects of 3-indolemethanol on murine hepatoma and human osteosarcoma cells in vitro. This compound has been shown to have oral hypoglycemic activity and to inhibit cancer cell growth. 3-Indolemethanol has also been shown to modulate signal pathways, such as the MAPK pathway, which may lead to pro-apoptotic protein activation or inhibition of physiological effects.</p>

<p>(+/-)-Heraclenin is a naturally occurring coumarin, which is a class of organic compounds notable for diverse biological activities. This compound is primarily sourced from various plant species belonging to the family Apiaceae, such as Heracleum species. Coumarins like (+/-)-heraclenin are known for their ability to modify biological responses due to their chemical structure.</p>

<p>5,5'-Diamino-2,2'-bipyridine is an acidic metalloporphyrin that has been shown to react with epoxides to form nucleophilic adducts. This compound can be used as a ligand for lanthanide ions and reacts with aminopyridine to form bromoethane. 5,5'-Diamino-2,2'-bipyridine has been shown to have carcinogenic properties and may induce bromoethane mutagenicity in the liver. This compound is also mutagenic when added to propylene carbonate. 5,5'-Diamino-2,2'-bipyridine is luminescent in air or water when exposed to UV light.</p>

<p>Geiparvarin is a cytotoxic compound, which is a plant-derived chemical with notable bioactivity. It is sourced from the roots of the Daflon plant, known for various natural compounds with potential therapeutic effects. Geiparvarin acts by interfering with cellular processes, leading to apoptosis in malignant cells. This mode of action is particularly significant in the study and development of anticancer therapies.</p>

<p>6-Mercaptopurine is a purine analog that suppresses the production of white blood cells by inhibiting the enzyme thiopurine methyltransferase. It has been used to treat bowel disease and also for long-term suppression of the immune system in patients with autoimmune diseases. 6-Mercaptopurine is metabolized to 6-mercaptopurine, which is then converted to dinucleotide phosphate (dNTP) by group P2 enzymes. This conversion allows 6-mercaptopurine to inhibit dNTP synthesis and cell division. The effects of 6-mercaptopurine are potentiated when given in conjunction with azathioprine, another drug that inhibits purine metabolism. 6-Mercaptopurine is not active against human serum albumin or erythrocytes because it cannot be cleaved into an active form by these proteins. However, it does inhibit enzyme activities such as DNA polymerase, RNA polymerase, and protein</p>

<p>(9R,11S,14S,16R,17R)-6,6,9-Trifluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-8,11,12,14,15,16-hexahydro-7H-cyclopenta[a]phenanthrene 3-one is a congestive heart failure drug that belongs to the group of cardiotonic drugs. It has high resistance to elution and is used in the diagnosis of autoimmune diseases. (9R,11S) 6-(1′Hexahydrocyclohexa[b]pyrrolo[2′1′b]indolizinium bromide) is a nitrogenous compound that has been employed as a pharmaceutical preparation for the treatment of cardiac disorders. The biological properties of (9R) 11-(2′Hydroxyacetyl</p>

<p>Lauryl isoquinolinium bromide is a pyridinium cationic surfactant that is used as a diagnostic agent and pharmaceutical preparation. It is also used as an antimicrobial agent in liquid chromatography, which is a technique to separate chemical compounds. Lauryl isoquinolinium bromide has been shown to be effective against Gram-positive bacteria such as Staphylococcus aureus and Enterococcus faecalis, and Gram-negative bacteria such as Pseudomonas aeruginosa. Lauryl isoquinolinium bromide has also been shown to be effective against yeast such as Candida albicans. Lauryl isoquinolinium bromide is not effective against viruses or fungi. This agent can be used to enhance the permeability of membranes during cross-linking reactions between polymers.</p>

<p>6-Methylpurine is a product of the nucleotide metabolism in E. coli, which is a model organism for protein synthesis. 6-Methylpurine inhibits protein synthesis and exerts significant cytotoxicity. It has been shown to inhibit the enzyme activities of DNA polymerase alpha, DNA ligase, and RNA polymerase, as well as other enzymes involved in nitrogen metabolism. 6-Methylpurine has been shown to be an analog of adenine and has a similar reaction mechanism. The uptake of 6-methyl purine by cells is mediated by hydrogen bonds with amino acid residues on the cell membrane surface. This molecule also forms glycosidic bonds with ribose sugar groups on cellular surfaces. 6-Methylpurine plays an important role in energy metabolism through its incorporation into glucose and glycogen molecules.</p>

<p>1-Acetyl-5-bromoindole is a high quality reagent that is useful as an intermediate in the synthesis of a wide range of complex compounds. It can be used as a speciality chemical for research purposes or to make other chemicals. 1-Acetyl-5-bromoindole is also needed for the synthesis of indoles, which are useful scaffolds and building blocks in organic chemistry. This compound can be used to form reactions with other chemical compounds and can be used to create versatile building blocks.</p>

<p>Methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-[(E)-3-iodoprop-2-enyl]-8-azabicyclo[3.2.1]octane-2-carboxylate is an imaging agent that is used to diagnose and treat bowel diseases. It has pharmacokinetic properties that allow for a more accurate diagnosis of eye disorders and bowel disease. Methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-[(E)-3-iodoprop-2-enyl]-8-azabicyclo[3.2.1]octane-2-carboxylate is a DPPIV inhibitor that modulates the dopamine transporter in the brain by binding to its extracellular site of action on dopamine transporter proteins and blocking the reuptake of dopamine into the pres</p>

<p>1,1'-Bicyclo[1,1,1]pentane-1,3-dicarboxylic acid is a diacid that has been found to be effective in the synthesis of many organic compounds. It can be used as a building block for other molecules with different functional groups and is an excellent bioisostere for disulfides. The addition of 1,1'-bicyclo[1,1,1]pentane-1,3-dicarboxylic acid to a nucleophilic compound can be used to synthesize an ester. This molecule can also undergo cross-coupling reactions with halogens such as chlorine or bromine. The crystal x-ray diffraction pattern indicates that this molecule has a linear structure.</p>

<p>Indole-3-carboxaldehyde is a chemical compound that is used as an antimicrobial agent. The biological properties of this compound are not well studied, but it has been shown to be effective against bacteria and fungi. Indole-3-carboxaldehyde has been shown to inhibit the enzyme activity of sodium carbonate, which is involved in the production of lactic acid in bacteria. This effect may contribute to its antibacterial activity. Indole-3-carboxaldehyde is also a potential anticancer agent because it can bind to toll-like receptor 4 (TLR4). Indole-3-carboxaldehyde reacts with sulfa drugs through a mechanism similar to the reaction between hydrogen peroxide and potassium permanganate. It has been shown that indole-3-carboxaldehyde can be used as a pesticide for plants and as an electrochemical impedance spectroscopy probe for histological analysis.</p>

<p>6-Benzylamino-7-deazapurine is a drug that has been shown to be effective in the treatment of pancreatic cancer. It is a monomer that reacts with nucleophiles such as 6-mercaptopurine, which are present in the human lung. The reaction generates an exergonic molecule that can be used to generate ATP and regenerate NAD+ during irradiation. This process has been observed using kinetic studies on human colon adenocarcinoma cells. 6-Benzylamino-7-deazapurine can also react with triazole compounds to form a linker and increase the rate of polymerization. The optimization of this reaction time could lead to more efficient cancer treatments.</p>

<p>Betamethasone is a corticosteroid that is used to treat inflammation, ankylosing spondylitis, and rheumatoid arthritis. It has been shown to have efficacy in the treatment of pediatric patients with asthma, as well as animal models of cardiac arrest and stroke. Betamethasone has also been shown to be effective in the treatment of potassium ion-associated death due to cardiac arrhythmia or repolarization abnormalities. This drug can be administered orally or topically; it binds to the glucocorticoid receptor on cells and modulates gene transcription. The primary mechanism of action for betamethasone is not fully understood but may involve inhibition of protein synthesis and suppression of inflammatory cells.</p>

<p>3-(4-Fluorobenzoyl)-6-Methoxy-2-Methyl-1H-Indole-1-Acetic Acid is a prodrug that is metabolized to 6-fluoro-3,4 dioxo tamoxifen in the liver. It has been shown to have anticholinergic, cytosolic calcium and c1-4 alkyl properties. 3-(4-Fluorobenzoyl)-6-Methoxy-2-Methylindole Acetic Acid also has a basic group, cyclopentane ring, and pyridine ring.</p>

<p>5-Chloroindole-3-acetic acid (5CI3A) is a compound that belongs to the indole class of compounds. It is structurally similar to the amino acid tryptophan, which makes it a good template molecule for the synthesis of other indoles. 5CI3A is mainly found in plants and bacteria, where it acts as an auxin. In plants, 5CI3A stimulates cell elongation and leaf growth by interacting with plant hormones such as auxins and gibberellins. This compound also binds to serum albumin, which may be responsible for its low toxicity in humans. 5CI3A has been shown to inhibit the activity of human serum albumin by forming hydrogen bonds with it. This inhibition reduces the binding affinity of 5CI3A for other proteins in serum, making it less likely to interact with them than if there were no binding competition.</p>

<p>Bergaptol is a naturally occurring furanocoumarin, which is a compound derived from plants, particularly from the Rutaceae family such as bergamot and other citrus species. It is primarily characterized by its chemical structure containing a furan ring fused to a coumarin moiety. Bergaptol acts primarily through its interaction with biological systems by inhibiting certain enzymatic activities and interfering with the biological pathways that involve reactive oxygen species. This compound exhibits antioxidant properties, reducing oxidative stress by scavenging free radicals and thereby protecting cells from damage.</p>

<p>Ethyl 5-Nitroindole-2-Carboxylate is a precursor to the anti-HIV drug Delavirdine. It is synthesized by condensation of ethyl pyruvate and urea derivative in the presence of thionyl chloride. This compound can be used as an intermediate in the synthesis of other compounds such as ethyl ester and ethyl pyruvate. The chemical reaction is carried out at room temperature using a chlorinated solvent such as methylene chloride or chloroform. Ethyl 5-nitroindole-2-carboxylate can also be used for the synthesis of other drugs, including antitumor agents.</p>

<p>2,4-Dihydroxyquinoline is a malonic acid derivative that is used as an antimicrobial agent. It is a diazonium salt that can be synthesized from 2-chloro-4-nitrobenzene and malonic acid. The reaction mechanism for this compound involves the formation of a diazo intermediate, which reacts with the amine to form a quinoline. This compound has been shown to have antibiotic properties and is able to inhibit the growth of bacteria such as Salmonella typhi, Mycobacterium tuberculosis, Escherichia coli, and Staphylococcus aureus. 2,4-Dihydroxyquinoline has also been shown to have anticancer activity in vitro on human liver cells (HepG2) and human hepg2 cells.</p>

<p>Indole-2-carboxylic acid is a potent inducer of the cytochrome P450 enzyme. It has been shown to bind to the active site of the enzyme and inhibit its activity. Indole-2-carboxylic acid is an acidic molecule with two hydrogen atoms that are capable of forming an intermolecular hydrogen bond, which may be responsible for its ability to bind to the enzyme. This compound has been shown to inhibit the activity of other enzymes such as xanthine oxidase and phosphodiesterase, which are involved in chemical reactions that produce reactive oxygen species (ROS). ROS are implicated in neuronal death and Parkinson's disease.</p>

<p>Isoquinoline-4-carbaldehyde is an aldehyde chemical that has been synthesized in the laboratory. It is a chiral molecule with one asymmetric carbonyl group. Isoquinoline-4-carbaldehyde is a potential precursor to naphthyridine, which can be used as a building block for the synthesis of natural products. Isoquinoline-4-carbaldehyde has been shown to have phosphine properties, and it can be used as a ligand in transition metal complexes. The molecule has been shown to exist in two forms, which coexist in equilibrium and can undergo interconversion.</p>

<p>6-Bromo-2-oxindole is a crystalline compound with a molecular formula of C10H6BrO. It has been shown to have a high efficiency in the production of butyric acid and other organic acids. 6-Bromo-2-oxindole is also used in electron microscopy studies as an electron acceptor, and can be used for producing polymers with crystalline structures and dihedral angles. The compound has been shown to inhibit the growth of breast cancer cells by preventing the synthesis of mda-mb-231 breast cancer cells. It also has been shown to inhibit the production of isoindigo and morphology.</p>

<p>6-Hydroxy-4-methylcoumarin is a chemical compound that serves as a lactone derivative. It is commonly derived from synthetic sources through various organic reactions involving resorcinol and ethyl acetoacetate. The compound functions primarily through its ability to absorb ultraviolet light and fluoresce, making it highly valuable in spectroscopic analyses.</p>

<p>4-Hydroxy-2-methylindole is an organic compound that belongs to the class of metal salts. It can be obtained as a white solid by reacting indole with alkali metal hydroxide or alkali metal carbonate in the presence of water at high temperatures. The reaction yields 4-hydroxy-2-methylindole and hydrogen chloride gas, which are removed by distillation. 4-Hydroxy-2-methylindole is used in the production of epichlorohydrin, which is a raw material for polyurethane resins and olefins.</p>

<p>4,4'-Dinitro-2,2'-bipyridine-N,N'-dioxide is a fine chemical with a high quality. It is a versatile building block with a wide range of applications in research and as a reagent. The compound is used in the synthesis of organic compounds and many other products. This product can be used as an intermediate for the production of more complex compounds or scaffolds. 4,4'-Dinitro-2,2'-bipyridine-N,N'-dioxide has been shown to be useful in the synthesis of pharmaceuticals and agrochemicals.</p>

<p>4,6-Dimethoxyindole is a molecule that can be used as an amide or chloride. The molecular modeling study indicated that the 4,6-dimethoxyindole is hydrophobic and has a molecular weight of 164.4 g/mol. In the acetylation reaction, the 4,6-dimethoxyindole was synthesized with an acetyl group on one side of the molecule and an acetate group on the other side of the molecule. This molecule has shown to have anticholinesterase activity in vitro and can be used as an antibiotic. The synthesis of this molecule was confirmed by X-ray diffraction analysis, which showed that it had a crystal structure with two molecules in space group P2(1)2(1).</p>

<p>Please enquire for more information about 3-(3,4-dimethoxyphenyl)-4-(hydroxyimino)-1,6,6-trimethyl-5,6,7-trihydro1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-Deazaxanthine is a purine derivative that has been shown to have antiangiogenic properties. It inhibits the growth of cancer cells by inhibiting the synthesis of vascular endothelial growth factor (VEGF), which is a potent angiogenic factor. 7-Deazaxanthine also binds to the VEGF receptor, preventing it from binding to VEGF. The x-ray crystal structures and kinetic data for 7-deazaadenosine suggest that this compound may be an inhibitor of hydrogen bonding interactions between amino acids in protein molecules, leading to its antiangiogenic activity. 7-Deazaxanthine does not prevent the activation of tyrosine kinases or phosphatases. In addition, this compound has been shown to inhibit the proliferation of breast cancer cells in culture and in vivo studies using mouse models. This drug also has glycosidic bond, which can result in a variety of chemical structures due to different types of glycos</p>

<p>Indoline-2-carboxylic acid is a photophysical molecule with an absorption maximum at 518 nm. It has been shown to inhibit the activity of enzymes such as cyclooxygenase, lipoxygenase, and monoamine oxidases. This compound has been found to be effective in the treatment of cancer cells. Indoline-2-carboxylic acid is also used in pharmaceutical preparations, where it binds to enantiomers of other molecules and inhibits their biological activity. Indoline-2-carboxylic acid reacts with hydrochloric acid to form allyl carbonate and amide.</p>

<p>6-Methoxyindoline-2,3-dione is an indole alkaloid that has been isolated from the leaves of plants in the genus Apiaceae. It is synthesized by a reaction system that involves the oxidation of 6-methoxyindole to the corresponding oxindole and subsequent reduction to the desired product. The cytotoxicity of 6-methoxyindoline-2,3-dione has been demonstrated using a fluorescent assay with cancer cells. The compound binds to and activates cb2 receptors, which are expressed on immune cells and have been shown to be involved in inflammatory processes.</p>

<p>5-Cyano-1H-indole-2-carboxylic acid is a high quality reagent that is used as an intermediate in the synthesis of complex compounds. It can also be used as a building block for the synthesis of speciality chemicals and research chemicals. The versatile nature of this compound makes it useful as a reaction component in the synthesis of many different types of compounds, including fine chemicals and pharmaceuticals. 5-Cyano-1H-indole-2-carboxylic acid is available commercially with CAS No. 169463-44-9.</p>

<p>2-Thioxanthine is a hydrated form of xanthine, which is a purine base that occurs in all living cells. This compound has been shown to be able to inhibit the growth of resistant mutants and the formation of atherosclerotic lesions in mice. 2-Thioxanthine also inhibits the transfer reactions that are required for bacterial DNA synthesis. The stability of 2-thioxanthine can be increased by forming stable complexes with hydrochloric acid and by reducing the pH to less than 7. 2-Thioxanthine has been shown to have genotoxic effects on mouse liver cells and human fibroblasts, as well as pharmacological properties against cardiovascular disease.</p>

<p>5-Chloro-3-methyl-1H-indole-2-carboxylic acid (5CMC) is a versatile building block and research chemical. It has been shown to be an effective intermediate for the synthesis of many complex compounds with interesting pharmacological properties. 5CMC is also used as a speciality chemical in the production of pharmaceuticals, agrochemicals, and other chemicals. The compound is a fine chemical that can be used in various research and industrial applications.</p>

<p>3-Quinuclidinol is an alkaloid that is found in the bark of Erythroxylum coca, a plant that has been used for centuries to combat hunger and altitude sickness. It is also found in the leaves of various plants such as khat, betel nut and tea leaves. 3-Quinuclidinol is a nicotinic acetylcholine receptor agonist, which means it stimulates the receptors in the brain that are responsible for transmitting messages from one nerve cell to another. 3-Quinuclidinol also activates certain types of protein kinase enzymes, which play a role in regulating metabolism.</p>

<p>1-Benzyl-3-hydroxy-1H-indazole is a hydrophilic matrix that can be used to deliver drugs. The hydrophilicity of the matrix allows it to dissolve in water and form a paste when mixed with water. The drug or drug formulation is dispersed within the paste and delivered to the site of action by the matrix. 1-Benzyl-3-hydroxy-1H-indazole has shown inhibition of inflammation, which may be due to its ability to inhibit prostaglandin synthesis. 1BHI can also be used for electroreduction reactions, such as reduction of metal ions, at temperatures ranging from -10°C to +20°C.</p>

<p>2-Mercapto-5-benzimidazole sulfonic acid sodium salt dihydrate is a molecule that can be used in devices. It has been shown to reversibly change the morphology of a monolayer and to generate asymmetric structures. 2-Mercapto-5-benzimidazole sulfonic acid sodium salt dihydrate can be used to generate fluorescent emulsions, which are systems where the magnetic particles are suspended in an oil droplet and illuminated by light of an appropriate wavelength. The molecules that make up 2-Mercapto-5-benzimidazole sulfonic acid sodium salt dihydrate have been shown to function as acceptors for molecular orbitals, which are wave functions that describe electron distribution around the atomic nucleus. These properties make it a promising candidate for use in microscopy techniques, such as scanning tunneling microscopy (STM) or atomic force microscopy (AFM).</p>

<p>Bis(2,2'-bipyridine)-4'-methyl-4-carboxybipyridine-ruthenium N-succinimidyl ester-bis(hexafluorophosphate) is a molecule that inhibits the activity of matrix metalloproteinases. It binds to the active site of the enzyme and blocks its activity. This drug has been shown to be effective in inhibiting the activity of MMPs in cells, but not in tissue culture because it does not cross cell membranes. Bis(2,2'-bipyridine)-4'-methyl-4-carboxybipyridine-ruthenium N-succinimidyl ester-bis(hexafluorophosphate) has also been shown to have a low detection limit and can detect low levels of matrix metalloproteinase activity in cells.</p>

<p>5-Hydroxy-2-methylindole is a product that transfers serotonin and melatonin, which are neurotransmitters. It can be used in animal studies to investigate the effects on cancer cells and its potential as an anti-cancer agent. 5-Hydroxy-2-methylindole can also be used to stabilize nitro compounds, such as TNT and RDX, by inhibiting the oxidation of these substances. This compound has been shown to have antiviral properties against HIV and HSV and may also have potentials for treating Alzheimer's disease. 5-Hydroxy-2-methylindole is synthesized by reacting indole with hydrogen peroxide in the presence of a halogeno (e.g., chlorine) or ferrous salts. The reaction rate of this synthesis depends on the concentrations of these reactants.</p>

<p>Poncimarin is a citrus-derived flavor compound, which is extracted from the peels of citrus fruits. Its mode of action involves mimicking natural citrus flavors, providing authentic taste profiles through a combination of volatile compounds that resemble those found in fresh citrus. The primary application of Poncimarin lies in its utilization as a flavoring agent in the food and beverage industry. It is incorporated to enhance the sensory attributes of products like beverages, confectioneries, and baked goods, delivering a refreshing citrus note that is both recognizable and appealing. Poncimarin's efficacy is attributed to its ability to integrate seamlessly with the existing flavor matrices of these products, ensuring a balanced and natural sensory experience. Its use extends to applications requiring stable, long-lasting flavor profiles, contributing to product innovation and development within sensory science.</p>

<p>Applications 6-Chloropurine, Hydrochloride (cas# 88166-54-5 ) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,2-Diazabicyclo[2.2.2]octan-3-one is an intermediate used in the synthesis of Bicyclo Risperidone (B382800), which is an impurity of Risperidone (R525000); a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988); Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990); Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>

<p>Applications Quinoline derivative used in the preparation of compounds with anticonvulsant activity as well as compounds with potent antibacterial activity against gram-positive pathogens.<br>References Guo, L. et al.: Eur. J. Med. Chem., 44, 954 (2009); Jarvest, R.L. et al.: J. Med. Chem., 45, 1959 (2002);<br></p>

<p>Applications 1,4-Dioxa-8-azaspiro[4.5]decane-8-carboxylic Acid 1,1-Dimethylethyl Ester (cas# 123387-51-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Benzyl-5-bromoindole<br></p>

<p>Applications 2-(Cyanomethyl)-1H-indole-1-carboxylic Acid tert-Butyl Ester-13C,15N is an isotope labelled intermediate in the synthesis of endothelial lipase inhibitors.<br></p>

<p>Applications 2-Acetamido-6-chloro-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (cas# 137896-02-7) is a compound useful in organic synthesis.<br>References Matsuda, A., et al.: J. Med. Chem., 35, 241 (1992),<br></p>

<p>Applications A labelled intermediate of Irbesartan (I751000).<br>References Gillis, J., et al.: Drugs, 54, 885 (1997), Chando, T., et al.: Drug Metab. Disps., 26, 408 (1998), Hines, J., et al.: Eur. J. Pharmacol., 384, 81 (1999)<br></p>

<p>Applications (S)-Benzyl 2-(5-Bromo-1H-indole-3-carbonyl)pyrrolidine-1-carboxylate is an intermediate in the synthesis of ent-Eletriptan (E505005), an enantiomeric impurity of the serotonin 5-HTIB/ID receptor agonist Eletriptan (E505000).<br>References Orita, A., et al.: Green Chem., 3, 13 (2001);<br></p>

<p>Applications 1,1,2-Trimethyl-1H-benzo[e]indole-d6 is a labelled analogue of 1,1,2-Trimethyl-1H-benzo[e]indole (T896032). It is a useful research chemical.<br></p>

<p>Applications A reagent used in the preparation of biologically active Azaindoles.<br>References Minakata, S., et al.: J. Agric. Food Chem., 45, 2345 (1997),<br></p>

<p>Applications 2-Chloro-5-nitroquinoline is used in the synthesis of potent, orally active corticotropin-releasing factor-1 receptor antagonists.<br>References Takeda, K., et al.: BIoorg. Med. Chem., 20, 6559 (2012); Verheij, M.H.P., et al.: J. Med. Chem., 55, 8603 (2012); Takeda, K., et al.: Bioorg. Med. Chem. Lett., 22, 5372 (2012);<br></p>

<p>Applications 2-(2-Chloroethyl-d4)-1H-isoindole-1,3-dione (cas# 1252995-10-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Amino-4-bromo-5-phenylpyrazole (cas# 2845-78-5) is a compound useful in organic synthesis.<br></p>