Organometallic Ligands
In this category, you will be able to find a large number of organometallic molecules used as ligands in biomolecules. These organometallic ligands can be used in organic chemistry and synthesis in the laboratory. They play a critical role in forming coordination complexes and catalyzing various chemical reactions. At CymitQuimica, we offer a diverse selection of high-quality organometallic ligands to support your research and industrial needs.
Subcategories of "Organometallic Ligands"
- Buchwald Ligands(22 products)
- DPEN(4 products)
- DPHEN(4 products)
- JOSIPHOS(4 products)
- Phosphine(497 products)
- Porphirines(75 products)
Found 2889 products of "Organometallic Ligands"
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GC376 sodium
CAS:GC 376 is an inhibitor of the main protease Mpro (3CLpro) in coronaviruses as well as picornaviruses. This broad-spectrum antiviral compound has been used as investigational veterinary drug for treatment of feline infectious peritonitis virus (FIPV) infections. Recent studies also showed that GC 376 inhibits the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.03 μM and EC50 of 3.37 μM.
Formula:C21H30N3NaO8SPurity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:507.53 g/molKifunensine - Bio-X ™
CAS:Kifunensine is a small molecule inhibitor that was designed and synthesized to inhibit plant and animal α-mannosidase I. It is a potent and specific inhibitor with IC50 in nanomolar range. It inhibits the enzyme isoforms in Golgi apparatus (GMI) and endoplasmatic reticulum (ERMI). The compound prevents mannose trimming on glycoproteins and shifts the glycoform content from complex to oligomannose type. Used for the production of recombinant therapeutic glycoproteins with mannose rich N-linked glycans.Formula:C8H12N2O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:232.19 g/molNicaraven
CAS:Hydroxyl radical scavenger; anti-vasospasticFormula:C15H16N4O2Purity:Min. 95%Molecular weight:284.31 g/molIrbesartan - Bio-X ™
CAS:Irbesartan is an angiotensin II receptor antagonist that is used to treat hypertension and congestive heart failure. It is also used to delay the progression of diabetic nephropathy. This drug works to works to relax smooth muscles and lower blood pressure.Formula:C25H28N6OPurity:Min. 95%Color and Shape:PowderMolecular weight:428.53 g/mol7-Prenyloxycoumarin
CAS:7-Prenyloxycoumarin is a naturally occurring compound, often categorized as a phytochemical, which is primarily isolated from various plant sources including the Rutaceae family. This compound exhibits intriguing biochemical properties due to its unique molecular structure, primarily the presence of a prenyloxy group attached to the coumarin core. The mode of action of 7-Prenyloxycoumarin primarily involves its ability to interact with biological membranes and proteins, leading to modulation of enzymatic activity and disruption of pathogen cell walls.Formula:C14H14O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:230.26 g/molQ-VD-OPH
CAS:Inhibitor of caspases; broad spectrumFormula:C26H25F2N3O6Purity:Min. 98.00 Area-%Color and Shape:PowderMolecular weight:513.49 g/molBRD 6989
CAS:A small molecule inhibitor with high selectivity for CDK8 over CDK19. Increases IL-10 production in stimulated human and murine macrophages and dendritic cells. Modulatory action on inflammatory responses has therapeutic potential.Formula:C16H16N4Purity:Min. 95%Color and Shape:SolidMolecular weight:264.33 g/molPonalrestat
CAS:Ponalrestat is an aldose reductase inhibitor, which is a synthetic compound developed for pharmacological purposes. It originates from chemical synthesis designed to target and inhibit the enzyme aldose reductase effectively. The mode of action involves the competitive inhibition of aldose reductase, an enzyme involved in the polyol pathway of glucose metabolism. By preventing the reduction of glucose to sorbitol, it reduces sorbitol accumulation associated with diabetic complications.Formula:C17H12BrFN2O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:391.19 g/molLicofelone
CAS:Dual COX/5-LO inhibitor; anti-inflammatory; analgesic
Formula:C23H22ClNO2Purity:Min. 95%Color and Shape:PowderMolecular weight:379.88 g/molVolitinib
CAS:Inhibitor of c-Met kinaseFormula:C17H15N9Purity:Min. 95%Color and Shape:White PowderMolecular weight:345.36 g/molL 838417
CAS:Selective partial GABAA receptor antagonist of subtypes α1, α2, α3, α5 subunits. Non-sedative anxiolytic effects demonstrated in vivo, without compromising motor activity. Anti-nociceptive and anti-inflammatory activities also demonstrated in vivo.Formula:C19H19F2N7OPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:399.4 g/molSemaglutide
CAS:Anti-diabetic and anti-obesity drug. We also have the heavy labelled material, CRB1301886. Cymit Quimica provides this product solely for uses within the scope of any statute or law providing for an immunity, exemption, or exception to patent infringement (“Exempted Uses”), including but not limited to 35 U.S.C. § 271(e)(1) in the United States, the Bolar type exemption in Europe, and any corresponding exception to patent infringement in any other country. It is the sole responsibility of the purchaser or user of this product, and the purchaser or user of this product agrees to engage only in such Exempted Uses, and to comply with all applicable intellectual property laws and/or regulations. The purchaser of this product agrees to indemnify Cymit Quimica against all claims in connection with the performance of the respective commercial agreement (e.g. supply agreement) and possible infringements of intellectual property rights.Formula:C187H291N45O59Purity:Min. 99.0 Area-%Color and Shape:PowderMolecular weight:4,113.58 g/molMK 4827
CAS:Inhibitor of PARP1 and PARP2 enzymes
Formula:C19H20N4OPurity:Min. 96 Area-%Color and Shape:White PowderMolecular weight:320.39 g/molCariprazine
CAS:Partial agonist of D2 and D3 dopamine receptors; anti-psychoticFormula:C21H32Cl2N4OPurity:Min. 95%Color and Shape:White PowderMolecular weight:427.41 g/molCandesartan - Bio-X ™
CAS:Candesartan is a drug that belongs to the class of angiotensin II receptor antagonists and is used to treat hypertension. It is used in combination therapy with other drugs, such as hydrochlorothiazide and amlodipine, to lower blood pressure. Candesartan inhibits the formation of angiotensin II, the receptor which causes vasoconstriction and increased blood pressure.
Formula:C24H20N6O3Purity:Min. 95%Color and Shape:PowderMolecular weight:440.45 g/molNL 1
CAS:Inhibits the mitochondrial outer mebrane protein mitoNEET, anti-leukaemicFormula:C18H25NO3SPurity:Min. 95%Color and Shape:SolidMolecular weight:335.46 g/molRS 127445 hydrochloride
CAS:A selective antagonist of serotonin 5-HT2B receptors, inhibiting inositol phosphate formation and calcium release. Blocks 5-HT-induced contraction in rat stomach fundus. Reduces fecal output in vivo, upon inhibition of 5-HT2B by RS 127445, demonstrating a potential role for this receptor in colonic motility. Inhibits visceral hypersensitivity induced by restraint stress or colonic inflammation.Formula:C17H16FN3·HClPurity:Min. 95%Color and Shape:White To Yellow SolidMolecular weight:317.79 g/molPF 670462
CAS:Casein kinase (CK1ε and CK1ÎŽ) inhibitorFormula:C19H20FN5•(HCl)2Purity:Min. 95%Molecular weight:410.32 g/molCetilistat - Bio-X ™
CAS:Cetilistat is a drug that is used to treat obesity. This drug inhibits the enzyme pancreatic lipase and so it prevents triglycerides from being hydrolyzed into absorbable free fatty acids.Formula:C25H39NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:401.58 g/molDapagliflozin - Bio-X ™
CAS:Dapagliflozin is a sodium-glucose cotransporter subtype 2 (SGLT2) inhibitor that can be used in the treatment of diabetes mellitus type 2. It inhibits glucose reabsorption in the proximal tubule of the nephron and results in glycosuria, which helps to improve glycaemic control. Also, Dapagliflozin is used to lower the risk of sustained eGFR decline, end-stage renal disease, cardiovascular death, and hospitalization for heart failure in patients with chronic kidney disease who are at risk of progression.Formula:C21H25ClO6Purity:Min. 99 Area-%Color and Shape:PowderMolecular weight:408.87 g/molAR-R 17779 hydrochloride
CAS:AR-R 17779 is a selective agonist for α7 nicotinic acetylcholine receptors (nAChRs) (Ki value = 190 nM for rat α7 receptor). This compound has use as a tool to study the function of α7 nicotinic receptors. One such study revealed a role for α7 nicotinic receptors in nicotine-mediated excitatory effects on hippocampal learning and memory. AR-R17779 reduces formation of atherosclerotic plaques and abdominal aortic aneurysms in apolipoprotein E-deficient mice.Formula:C9H14N2O2•HClPurity:Min. 95%Color and Shape:White PowderMolecular weight:218.68 g/molPNU 159682
CAS:DNA alkylating agent; highly potent metabolite of nemorubicinFormula:C32H35NO13Purity:Min. 90 Area-%Color and Shape:Red PowderMolecular weight:641.62 g/molPF 06409577
CAS:Potent agonist of a1β1γ1 5′-adenosine monophosphate-activated protein kinase (AMPK). It binds to the allosteric drug and metabolite (ADaM) site at the α- and β- subunit interface of AMPK. It has potential for the treatment of diabetic nephropathy. PF 06409577 reduces infections caused by flaviviruses, mediated by changes in the metabolism of lipids in host cells.
Formula:C19H16ClNO3Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:341.79 g/molXylometazoline hydrochloride
CAS:alpha-adrenoceptor agonist; nasal decongestant
Formula:C16H25ClN2Purity:Min. 99 Area-%Color and Shape:PowderMolecular weight:280.84 g/molBX471 hydrochloride
CAS:BX471 hydrochloride is a selective antagonist of the C-C chemokine receptor type 1 (CCR1), which is synthesized through rigorous chemical processes. It operates by inhibiting the binding of chemokines to the CCR1 receptor, thus interfering with the signaling pathways that lead to inflammation and immune responses. This mechanism is specifically effective in modulating immune system functions and controlling pathophysiological responses in various tissue types.
Formula:C21H25Cl2FN4O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:471.35 g/molCYT 387
CAS:Inhibits JAK1 and JAK2 kinasesFormula:C23H22N6O2Purity:Min. 95%Color and Shape:PowderMolecular weight:414.46 g/molRoflumilast - Bio-X ™
CAS:Roflumilast is a selective phosphodiesterase-4 inhibitor that is used for the treatment of exacerbations in patients with chronic obstructive pulmonary disease (COPD). It is also used to treat plaque psoriasis. This drug has anti-inflammatory and immunomodulatory effects as it aids in increasing levels of cAMP.
Formula:C17H14Cl2F2N2O3Purity:Min. 95%Color and Shape:PowderMolecular weight:403.21 g/molDG 172 hydrochloride
CAS:Potent inverse agonist of peroxisome proliferator-activated receptor PPARβ and PPARδ with IC50 value of 27 nM. In mouse myoblasts, DG 172 enhanced recruitment of transcriptional corepressor and down-regulated transcription of PPARβ/δ target gene Angptl4. DG 172 also possess a PPARβ/δ-independent activity on bone marrow cells and promotes dendritic cell differentiation.Formula:C20H20BrN3•HClPurity:Min. 95%Color and Shape:SolidMolecular weight:418.76 g/molDovitinib base
CAS:Receptor tyrosine kinase inhibitor; anti-angiogenesis; anti-oncogenesisFormula:C21H21FN6OPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:392.43 g/molIsradipine
CAS:L-type calcium channel blockerFormula:C19H21N3O5Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:371.39 g/molThioglycosyl Naphthalimide
CAS:Thioglycosyl Naphthalimide is a highly potent human O-GlcNAcase (hOGA) inhibitor with good selectivity against human β-N-acetylhexosaminidase B (HsHexB).Formula:C30H40N4O7SPurity:Min. 95%Molecular weight:600.73 g/molHyp9
CAS:Hyp9 is an advanced biochemical reagent, which is derived from sustainably sourced natural compounds with a proprietary purification process. Its mode of action involves targeted binding to specific molecular sites, enabling the modulation of biochemical pathways with high precision.Formula:C18H26O5Purity:Min. 95%Color and Shape:PowderMolecular weight:322.4 g/molMitoxantrone hydrochloride
CAS:Inhibits DNA topoisomerase II; antineoplastic; immunomodulatory; antimicrobialFormula:C22H30Cl2N4O6Purity:Min. 97 Area-%Color and Shape:Dark Blue SolidMolecular weight:517.4 g/molSorafenib - Bio-X ™
CAS:Sorafenib is a drug that belongs to the class of multikinase inhibitors. It inhibits a number of kinases, including the Mcl-1 protein, which is involved in apoptosis along with blocking picolinic acid (PA), an endogenous metabolite involved in apoptosis signal transduction. Sorafenib also binds to epidermal growth factor receptor (EGFR) on the surface of cancer cells, inhibiting the production of proteins that are required for angiogenesis, thus blocking the formation of new blood vessels. Sorafenib may also inhibit P-glycoprotein (Pgp) activity. Overall, these cytotoxic effects give Sorafenib anti-tumor properties, inhibiting angiogenesis and cellular transformation, which are the two main processes of tumor growth and metastasis. Sorafenib has been shown to be effective against a range of solid tumors such as breast, prostate and lung cancers and is also used for the treatment of metastatic colorectal cancer and renal cell carcinoma. A combination therapy group found that sorafenib was more effective when used with interferon alfa-2b for the treatment of advanced renal cell carcinoma. Sorafenib also has the potential for drug interactions with other drugs that are metabolized by cytochrome P450 enzymes. Sorafenib is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C21H16ClF3N4O3Purity:Min. 98%Color and Shape:PowderMolecular weight:464.82 g/molFingolimod phosphate
CAS:Sphingosine-1-phosphate (S1P) receptor agonist; antineoplastic, immunosppressant
Formula:C19H34NO5PPurity:Min. 95%Color and Shape:PowderMolecular weight:387.45 g/molPadsevonil
CAS:Padsevonil is an investigational antiseizure medication, which is a synthetic pharmaceutical compound. It is derived from extensive medicinal chemistry research aiming to address complex seizure disorders resistant to conventional treatments. Padsevonil functions by exhibiting a dual mechanism of action. It binds to synaptic vesicle protein 2A (SV2A) with high affinity, similar to levetiracetam but with additional modulation of the benzodiazepine-sensitive gamma-aminobutyric acid-A (GABA-A) receptor. This combined activity potentiates its efficacy in stabilizing neuronal hyperactivity and dampening excitatory neurotransmission, providing a novel angle to tackle refractory seizures.Formula:C14H14ClF5N4O2SPurity:Min. 95%Molecular weight:432.8 g/mol(-)-Sparteine hydroiodide
CAS:Sparteine hydroiodide is the salt form of sparteine. This compound acts as an inhibitor of voltage-gated sodium channels. In organic chemisty, it is used for chiral synthesis.Formula:C15H26N2•HIPurity:Min. 95%Molecular weight:362.29 g/molCyamemazine
CAS:Cyamemazine is a neuroleptic medication, which is a member of the phenothiazine class of compounds. It is synthesized from derivatives of phenothiazine, a group of agents primarily found in pharmaceuticals. The mode of action of cyamemazine involves antagonism at dopamine D2 receptors in the central nervous system. This inhibition of dopamine activity is the principal mechanism through which it exerts its antipsychotic effects. Due to its receptor activity, cyamemazine is used primarily in the management of various psychotic disorders, including schizophrenia and acute psychoses. It also exhibits anxiolytic properties, making it effective in treating anxiety associated with these conditions. By modulating neurotransmitter pathways, cyamemazine helps to alleviate symptoms such as hallucinations, delusions, and agitation, offering therapeutic benefit in complex neuropsychiatric cases. As an atypical antipsychotic, it provides an option for patients who may not respond adequately to other treatments. Although primarily used in a clinical setting, ongoing research continues to investigate potential wider applications and efficacy in treating other mental health issues.Formula:C19H21N3SPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:323.46 g/molFG 7142
CAS:Partial inverse agonist of benzodiazepine sites of the GABAA receptors with anxiogenic properties. FG 7142 is a pharmacological stressor which generates anxiety in humans and in experimental animals such as rhesus monkeys and rodents. FG 7142 also reduces food intake and frequency of feeding in male and female rats.Formula:C13H11N3OPurity:Min. 95%Color and Shape:Yellow PowderMolecular weight:225.25 g/molSofalcone
CAS:Increases VEGF via heme oxygenase-1 modulation; anti-ulcer agentFormula:C27H30O6Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:450.52 g/molDilevalol hydrochloride
CAS:Controlled ProductBeta-adrenoceptor antagonist; anti-hypertensiveFormula:C19H24N2O3·HClPurity:Min. 95%Color and Shape:SolidMolecular weight:364.87Imiquimod maleate
CAS:Imiquimod maleate is an immune response modifier, which is a synthetic compound sourced from chemical synthesis. Its mode of action involves the activation of the immune system through the stimulation of toll-like receptor 7 (TLR7), leading to the induction of various cytokines, such as interferon-alpha, that initiate an antiviral and anti-tumor response.Formula:C18H20N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:356.4 g/molBrivanib alaninate
CAS:VEGFR2 a tyrosine kinase receptor inhibitor; antineoplasticFormula:C22H24FN5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:441.18123Bafilomycin A1
CAS:Inhibitor of vacuolar-type proton pumpFormula:C35H58O9Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:622.83 g/mol8-Deschloro-8-bromo-N-methyl desloratadine
CAS:Antagonist of platelet activating factorFormula:C20H21BrN2Purity:Min. 95%Color and Shape:PowderMolecular weight:369.3 g/molGlatiramer acetate
CAS:Controlled ProductUsed to treat multiple sclerosis; anti-inflammatoryFormula:(C9H11NO3•C6H14N2O2•C5H9NO4•C3H7NO2)x•XC2H4O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:623.65Tandospirone
CAS:Tandospirone is a psychotropic drug that acts as a selective serotonin receptor partial agonist. It is derived from a synthetic source, specifically targeting the 5-HT1A receptors in the brain. Tandospirone modulates serotonergic neurotransmission by binding to these receptors, which are associated with mood regulation. This action results in the anxiolytic and antidepressant effects observed with the drug.Formula:C21H29N5O2Purity:Min. 95%Molecular weight:383.49 g/molGefitinib hydrochloride
CAS:RIPK2 protein kinase inhibitor; EGFR inhibitorFormula:C22H24ClFN4O3·HClPurity:Min. 95%Color and Shape:PowderMolecular weight:483.36 g/molLumiracoxib - Bio-X ™
CAS:Controlled ProductLumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug that is used for the treatment of osteoarthritis. This drug inhibits prostaglandin synthesis via inhibition of COX-2.Formula:C15H13ClFNO2Purity:Min. 95%Color and Shape:PowderMolecular weight:293.72 g/molJNJ 10198409
CAS:Selective inhibitor of the platelet derived growth factor receptor PDGFRβ with IC50 value of 4.2 nM. JNJ 10198409 inhibits the PDGFRβ kinase activity and its downstream signalling leading to anti-proliferative and anti-angiogenic effects, which were confirmed in various tumoral cell lines.Formula:C18H16FN3O2Purity:Min. 95%Color and Shape:SolidMolecular weight:325.34 g/mol
