Carboxylic Acids

<p>Please enquire for more information about 4-(4-(tert-Butyl)phenyl)-2-indol-3-yl-4-oxobutanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(Benzimidazolylthio)acetic acid hydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cholesterol Phenylacetate is a fatty acid that has been shown to inhibit the synthesis of phosphatidylethanolamine, an important component in cell membranes. This leads to a decrease in the rate of malignant tumor growth and death protein production. Cholesterol Phenylacetate also inhibits the expression of pro-inflammatory genes, which may be due to its ability to inhibit fatty acid synthesis. This compound is effective in reducing atherosclerotic lesions and hyperproliferative diseases, such as cancer.</p>

<p>5-Bromo-2-methylbenzoic acid ethyl ester is a fine chemical used as a versatile building block in organic synthesis. It is also used as a reagent for the conversion of alcohols to alkyl bromides, and for the preparation of 2-bromoacetophenones from 2-bromobenzenes. 5-Bromo-2-methylbenzoic acid ethyl ester can be used as a useful intermediate in the synthesis of other compounds or in reactions with other chemicals. This product has high quality and can be used as a useful scaffold for synthesizing new compounds.</p>

<p>2-Indol-3-yl-4-oxo-4-phenylbutanoic acid is a plant derived compound that has been shown to be effective in inhibiting the growth of pea plants. It inhibits pea nodule formation by binding to the regulatory protein 2-aminoisobutyric acid (ABA) receptor, which is necessary for transport of ABA into the cell. In addition, 2I3O4PBA has been shown to inhibit transcriptional regulation of genes involved in plant growth and development. The mechanism of action for this compound is not fully understood, but it may involve chemical biology or genetic analyses.</p>

<p>Please enquire for more information about Ethyl 3-((3,4-dimethoxyphenyl)amino)-5-methyl-2,4-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4,5-dimethoxy-2-(morpholin-4-ylsulfonyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(2-(N-(4-(Trifluoromethoxy)phenyl)carbamoyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-((2,5-dichlorophenyl)amino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(Prop-2-enylamino)-5-methyl-2,4-thiazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4-(3-(Trifluoromethyl)phenylamino)-3,5-thiazolyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-((4-Ethyl-5-oxo-3-thioxo-2,4-thiazolidinylidene)methyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(2,4-Dibromophenoxy)acetic acid is a chemical compound with an empirical formula of C7H4Br2O4. The crystalline form of this compound has been analysed and optimised for surface analysis and crystallography. This molecule is also a model compound for coordination chemistry studies. Experimental data has been collected from bioassays that demonstrate the ligand's ability to bind to metal ions. X-ray crystallography has shown the molecular structure of (2,4-dibromophenoxy)acetic acid as a ligand in coordination with a metal ion in which the bromine atom is bonded to two oxygen atoms on the metal ion, forming a trigonal bipyramidal geometry.</p>

<p>Please enquire for more information about 4-(2,6,6-Trimethyl-4-oxo-5,6,7-trihydroindolyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-oxo-7-(benzyloxy)hydroquinoline-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The compound trans-3-(4-methylbenzoyl)acrylic acid is a potent and selective inhibitor of serine/threonine protein kinase. It has been shown to inhibit the proliferation of eosinophils in vitro, as well as to suppress the release of leukotrienes from human mast cells. The mechanism of action is by inhibiting phosphatidylcholine-specific phospholipase C, which leads to the inhibition of protein kinase C. This inhibition prevents the phosphorylation of various proteins, including cytoskeletal proteins that are required for cell division.</p>

<p>Please enquire for more information about 2-(4,5-Dimethoxy-2-(thiomorpholin-4-ylsulfonyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(3,4-Dimethoxyphenyl)-1,3-thiazolidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-((3,4-dimethoxyphenyl)amino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-[(4-Nitrophenyl)thio]benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 3-(3-pyridylamino)-5-methyl-2,4-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Camphorquinone-10-sulfonic acid hydrate is a soybean trypsin inhibitor that is used as a preparative agent in organic synthesis. It reacts with histidine, lysine residues, and other molecules to form a light-chain kinase that inhibits the action of the enzyme trypsin. Camphorquinone-10-sulfonic acid hydrate has been shown to be resistant to proteolysis by gastrointestinal enzymes. This agent also has diabetogenic properties by inhibiting the activity of membrane potential and chloride channels in pancreatic β cells. Camphorquinone-10-sulfonic acid hydrate forms an ion pair with choline, which can inhibit the enzyme acetylcholinesterase, leading to accumulation of acetylcholine at nerve endings.</p>

<p>Please enquire for more information about methyl 2-(4,5-dimethoxy-2-(((4-(trifluoromethyl)phenyl)amino)sulfonyl)phenyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-piperidinecarboxylic acid (3CFP) is a phenoxy carboxamide that is an anticonvulsant. 3CFP has been shown to be effective in animal models of seizure and has a potency that exceeds that of phenobarbital. It also has potent anticonvulsant activity against seizures induced by pentylenetetrazole and electroshock. 3CFP binds to the GABA receptor, which is important for the regulation of neuronal excitability and is the target for many types of antiepileptic drugs. The chlorine atom in 3CFP may contribute to its pharmacological properties because it can form a covalent bond with amino acids like cysteine, which are important for protein synthesis.</p>

<p>Please enquire for more information about 3-(N-(4-(Dimethylamino)phenyl)carbamoyl)pyridine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(2-(N-(3-Nitrophenyl)carbamoyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-((4-fluorophenyl)amino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ethyl 2-(4-(4-fluorophenylamino)-3,5-thiazolyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-((2-Fluorophenyl)amino)-4-methyl-1,3-thiazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(4-Bromophenyl)-2-indol-3-yl-4-oxobutanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about methyl 2-(4,5-dimethoxy-2-(morpholin-4-ylsulfonyl)phenyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-(benzylamino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(2-(4-Bromophenyl)-6,6-dimethyl-4-oxo-5,6,7-trihydroindolyl)benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(2-(N-(4-(Isopropyl)phenyl)carbamoyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about 2-(4-(3,5-Dichlorophenylamino)-3,5-thiazolyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about 2-(4,5-Dimethoxy-2-(((4-methoxyphenyl)amino)sulfonyl)phenyl)acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5,5-Dimethyl-2-(3-pyridyl)-1,3-thiazolidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(4-Bromophenyl)-2-(7-ethylindol-3-yl)-4-oxobutanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-((2-chlorophenyl)amino)-3,5-thiazolecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4-(Trifluoromethoxy)phenyl)-1,3-thiazolidine-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Applications Used in the preparatiom of esters of 6-aminohexanoic acid as antibacterial agents. EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carbo xy peptidase, plasmin, and plasminogen activator.<br>References Dolezal, P., et al.: Pharm. Res., 10, 1015 (1993), Vavrova, K., et al.: Curr. Med. Chem., 12, 2273 (2005), Holas, T., et al.: Bioorg. Med. Chem., 14, 7671 (2006),<br></p>

<p>Applications Androstenediol 17-Acetate is used in synthetic preparation for direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids. Androstenediol 17-Acetate is also obtained from Dehydro Epiandrosterone (D229585) which is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome.<br>References Ebeling, P., et al.: Lancet, 343, 1479 (1994); Morales, A.J., et al.: J. Clin. Endocrinol. Metab., 78, 1360 (1994); Ramachary, D.B., et al.: RSC Advances, 3, 13497-13506 (2013); Yahara, M., et al.: J. Toxicol. Sci., 2, 161 (1977);<br></p>

<p>Applications 4-​(Dimethyloxidoamino)​butanoic Acid Hydrochloride, is a metabolite of Lauramine Oxide (L178530), which is a frequently used amine oxide surfactant. It is strongly hydrophilic , and it forms normal micelles and normal liquid crystalline phases.<br>References Kocherbitov, v., et al.: J. Molec. Struct.: Theochem., 808, 111 (2007); Kocherbitov, v., et al.: J. Phys. Chem. B., 110 (27), 13649 (2006); Turan, T.S., et al.: Xenobiotica, 11, 447 (1981)<br></p>

<p>Applications tert-Butyl (3-(2-(2-(3-Aminopropoxy)ethoxy)ethoxy)propyl)carbamate is used as a reactant in the synthesis of gallium-labeled PET imaging agents for CXCR4 for potential cancer diagnosis.<br>References Poty, Sophie, et al.: Bioconjugate Chem., 27(3), 752-761 (2016)<br></p>

<p>Applications 4-(dimethylamino)-3-nitrobenzoic Acid (cas# 28096-56-2) is a useful research chemical.<br></p>

<p>Applications 2,5-Dimethylthiophene-3-boronic acid<br></p>

<p>Applications 2,4-Xylenesulfonic Acid, is used for the preparation of 2,4,5,6-Tetrachloro-m-xylene (T291555). It is also an intermediate for the synthesis of Diphenylbismuth arenesulfonates.<br>References Sharutin, V. V., et al.: Russian J. Gen. Chem., 70, 687 (2000);<br></p>

<p>Applications (R)-2-(Tetrahydropyranyloxy)propionic Acid can be employed to synthesize lactic acid oligomers, depsides, and depsipeptides on solid phase.<br>References Kuisle, O., et al.: Tetrahedron Lett. 40, 1203 (1999); Kim, S. et al. tetrahedron asymmetry 22, 1499 (2011)<br></p>

<p>Applications 3-Furoic Acid, is metabolized by Corynebacterium fascians from soil, limonoid metabolism based on a biological studies.<br>References Hasegawa, S., et al.: J. Arg. Food Chem., 31, 807 (1983)<br></p>

<p>Applications methyl 2,4-dichlorothiazole-5-carboxylate (cas# 861708-66-9) is a useful research chemical.<br></p>

<p>Applications 2-(Propylthio)nicotinic acid (cas# 175135-22-5) is a useful research chemical.<br></p>

<p>Applications 4-tert-Butoxyphenylboronic Acid is a compound used in the preparation of nitrophenylphenol via cross-coupling reaction of nitrohalobenzenes with phenylboronic acids and deprotection.<br>References Kumamoto, N., et al.: Preparation of nitrophenylphenol, JP 2001055360 (2001);<br></p>

<p>Applications Isopropenylboronic Acid Pinacol Ester, can be used as an intermediate in the synthesis of variety of cyclic and acyclic organic compounds. It is also shown that the α-Substituted Allyl/Croty of this compound can be used for highly Diastereo- and Enantioselective allylboration of aldehydes.<br>References Salaun, J. et al.: Topics in Curr. Chem. 1, 144 (1988); Chen, J. et al.: J. Amer. Chem. Soci., 135, 5316 (2013);<br></p>

<p>Applications 4-(3,4-dipropoxyphenyl)-4-oxobutanoic acid (cas# 568553-00-4) is a useful research chemical.<br></p>

<p>Applications 5-Hydroxytoluene-2,4-disulfonic Acid acts as a synthetic reagent in the sulfonation of 2 and 3-Methylphenol.<br>References Strandlund, G., et al.: Acta Chem. Scand., 33, 261 (1979)<br></p>

<p>Applications 2-​Hydroxy-​3-​phenyl-​acrylic Acid is a chemical reagent in the synthesis of an atropos biphenyl biphosphine ligand as well as in the synthesis of novel cinnamanilides as potential immunosuppressive agents.<br>References Shi, L. et al.: Eur. J. Med. Chem., 47, 585 (2012);<br></p>

<p>Stability Air Sensitive<br>Applications Ethyl 2-Mercapto-1-cyclohexenecarboxylate is a reagent used in the synthesis of anti-inflammatory compounds,<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lloret, G. et al.: J. Phys. Org. Chem., 22, 1188 (2009);<br></p>

<p>Applications A reactant used in the preparation of (-)-Amathaspiramide F.<br>References Sakaguchi, K. et al.: Tetrahedron, 65, 10355 (2009); Sakaguchi, K. et al.: Org. Lett., 10, 5449 (2008)<br></p>

<p>Applications ethyl 2-(methylamino)-2-oxoacetate (cas# 18522-95-7) is a useful research chemical.<br></p>

<p>Applications 4-Nitrobenzyl Acetoacetate acts as a reagent in the preparation of panipenem via esterification of nitrobenzyl alcohol followed by substitution, cyclizations and hydrogenation. Panipenem I is a new carbapenem antibiotic for the treatment of inflammation.<br>References Fang, H., et al.: hongguo Yaowu Huaxue Zazhi, 21, 216 (2011)<br></p>

<p>Applications Penta-2,4-dienoic acid (cas# 626-99-3) is a useful research chemical.<br></p>

<p>Applications O-Acetyl Mandelic Acid is a useful reagent for the synthesis of hindered triazolopyridinone derivatives.<br>References Ye, Z., et al.: Nat. Commun., 11, 3628 (2020)<br></p>

<p>Applications 4-Hydroxybut-2-ynoic Acid (cas# 7218-52-2) is a useful reagent for the green preparation of polyseleno-substituted enamines.<br>References Wang, Y. C., et al.: Green Chem., 20, 604 (2018)<br></p>

<p>Applications Di-tert-butyl azodicarboxylate is a reagent used in the preparation of acyl hydrazinedicarboxylates via photoorganocatalytic hydroacylation of dialkyl azodicarboxylates with aldehydes in presence of phenylglyoxylic acid as photocatalyst.<br>References Papadopoulos, G. N., et al.: Chem. Eur. J., 20, 13811 (2014);<br></p>

<p>Applications 3-(2-Aminoethoxy)propionic Acid (cas# 144942-89-2) is a compound useful in organic synthesis.<br></p>

<p>Applications tert-Butyl (2-(methoxy(methyl)amino)-2-oxoethyl)carbamate has been used as a reactant in the preparation of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 with potential use in osteoarthritis therapy.<br>References Durham, T.B., et. al.: J. Med. Chem., 57, 10476 (2014)<br></p>

<p>Applications Dimethyl cyclopentane-1,3-dicarboxylate (cas# 2435-36-1) is a useful research chemical.<br></p>

<p>Applications tert-Butyl Methylcarbamate is an substituent in the synthetic preparation of PF-06463922, a macrocyclic inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1).<br>References Johnson, T. W., et al.: J. Med. Chem., 57, 4720 (2014);<br></p>

<p>Applications Suberic Acid is used in the preparation of reduction-sensitive micelles affecting their cellular uptake. This has potential application in delivery of anticancer drugs. It is also used in the fluorescent detection of amidinium-carboxylate and amidinium formation.<br>References Cui, C. et al.: Biomat., 34, 3858 (2013); Kusukawa, T. et al.: Tetra., 68, 9973 (2012);<br></p>

<p>Applications Ethyl 4-Chloroacetoacetate (cas# 638-07-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Carboxyfuran-5-boronic acid, pinacol ester<br></p>

<p>Applications 3-(2,3-Dihydroxyphenyl)propionic acid is a degradation product of the aromatic compound Phenylpropionate (PP).<br>References Provencher, S., et al.: Biochemistry, 20, 33 (1981), Ferrandez, A., et al.: J. Bacteriol., 179, 2573 (1997), Torres, B., et al.: J. Biol. Chem., 278, 27575 (2003),<br></p>

<p>Applications Used in the synthesis of anti-tumor compounds comprising of hydroxyisovalerylshikonin analogs. Furthermore, the compound is a reagent in the synthesis of class II c-Met inhibitors, in the treatment of c-Met dependant tumors.<br>References Rao, Z. et al.: Eur. J. Med. Chem., 46, 3934 (2011); Liu, L. et al.: J. Med. Chem., 55, 1868 (2012);<br></p>

<p>Applications Eicosanedioic Acid is an intermediate used to prepare haloperidol-based bivalent ligands targeting dopamine D2-like receptors.<br>References Salama, I., et al.; Bioorg. Med. Chem. Lett., 24, 3753 (2014)<br></p>

<p>Applications Ethyl Isobutyrylacetate is used in the synthesis of piperazine derivatives as possible multireceptor atypical antipsychotics, affecting dopamine and serotonin receptor properties . Also used in the synthesis of pyrazinecarboxamide DGAT1 (diacylglycerol acyltransferase 1) inhibitors used in the treatment of obesity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chen, Y. et al.: J. Med. Chem., 56, 4671 (2013); J. Med. Chem., 55, 10610 (2012);<br></p>

<p>Applications 2-(Aminosulfonyl)benzoic Acid can be used as reactant/reagent in synthesis and pharmacological activity of γ-(phenyloxamido)- and γ-(phenylsulfonyloxamido)butanoic acids.<br>References Georgiyants, V. A., et al.: Farmatsevtichnii Zhurnal, 2, 34 (2010);<br></p>

<p>Applications 4-(Acetamidomethyl)benzoic acid<br></p>

<p>Applications Methyl 5-chlorothiophene-2-carboxylate (cas# 35475-03-7) is a useful research chemical.<br></p>