Aldehydes

<p>Z-Pro-Pro-aldehyde-dimethyl acetal is a neurotoxin that can be used to label lysosomal enzymes in cells. The labeling is stable and does not interfere with the enzymatic activity of the enzyme. It has been shown to exacerbate neurological disease in mice, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. Z-Pro-pro-aldehyde-dimethyl acetal binds to microglia cells and induces reactive oxygen species production, which may contribute to cell damage. This toxin also diffracts light at a wavelength of 630 nm when exposed to X-rays, making it useful for labeling lysosomal enzymes in tissue sections or cell supernatants.</p>

<p>3-Fluoro-2-hydroxybenzaldehyde is a colorless liquid with a sweet, aromatic odor. It has been shown to be an antibacterial agent against Gram positive bacteria and may have potential as a drug for the treatment of MRSA. 3-Fluoro-2-hydroxybenzaldehyde is used in the production of cellulose acetate and sodium sulfide. It is also used in the chemical reactions that form amines, hydroxyl groups, and chloride ions. It has been shown to inhibit mitochondrial respiration by chelating ring complexes in the respiratory chain. It also inhibits biological processes such as DNA synthesis, protein synthesis, and hydrogen bond formation.</p>

<p>3-Thien-2-yl-1H-pyrazole-4-carbaldehyde is a ligand that can be used to inhibit the activity of nicotine in the human liver. It has been shown to reduce chemical inhibitor activity globally and systematically, and it may have therapeutic potential for preventing death from tobacco use. 3-Thien-2-yl-1H-pyrazole-4-carbaldehyde binds to nicotine receptors by forming hydrogen bonds with the receptor's nicotinic acetylcholine binding sites. This prevents nicotine from binding to those sites, resulting in a reduction of the addictive properties of tobacco. 3TPCA is being developed as a drug candidate for treating tobacco use disorders.</p>

<p>Angiotensin-converting enzyme inhibitor; anti-hypertensive</p>

<p>4-Chloro-2-nitrobenzaldehyde is a reactive intermediate that has been used to investigate the reaction mechanism of protonation. It is an n-oxide and has been shown to react with calcium carbonate under acidic conditions, forming a stable product. 4-Chloro-2-nitrobenzaldehyde has also been used in the synthesis of amides and nitro compounds. This compound possesses two functional groups, which are a nitro group and a chloro group on the aromatic ring.</p>

<p>1H-Pyrazole-4-carbaldehyde is a chemical compound that inhibits the growth of bacteria by binding to the enzyme ribonucleotide reductase. It has been shown to have significant antifungal activity against Candida albicans and Saccharomyces cerevisiae, as well as in vitro antifungal activity against other fungi. The 1H-pyrazole-4-carbaldehyde has also been found to inhibit xanthine oxidase and nitric oxide synthase (NOS) in vitro and in vivo, which may be due to its ability to reduce oxidative stress. This chemical compound is a coumarin derivative and contains a pyrazole ring.</p>

<p>5-Bromo-2-(trifluoromethoxy)benzaldehyde is a chemical that is used as a reactant in organic chemistry. It can be used as a building block for the synthesis of complex compounds, or as an intermediate in the preparation of fine chemicals. 5-Bromo-2-(trifluoromethoxy)benzaldehyde is also useful in research and development. It has been used to synthesize pharmaceuticals, pesticides, and other organic compounds.</p>

<p>Ac-Val-Asp-Val-Ala-Asp-aldehyde is a pseudo acid that is used in molecular modeling and kinetic studies. Ac-Val-Asp-Val-Ala-Asp-aldehyde has been shown to be a potent inhibitor of caspase activity and has been shown to inhibit the activity of various other enzymes as well, including cyclohexane ring hydroxylases and nitroreductases. Ac-Val-Asp-Val-Ala-Asp--aldehyde analogs are being studied for their ability to bind to specific proteins or inhibit enzyme activities. Ac-- Val-- Asp-- Val-- Ala-- Asp-- aldehyde binds to the active site of caspase 3 and prevents it from cleaving its target protein, which leads to cell death.</p>

<p>Please enquire for more information about Cell-permeable Caspase-3 Inhibitor I trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3,5-Bis(trifluoromethyl)benzaldehyde is a synthetic compound that has been shown to inhibit cancer cell growth. It is a chromatographic reagent and an intermediate in the production of pharmaceuticals. 3,5-Bis(trifluoromethyl)benzaldehyde was shown to bind to the amino group of proteins and inhibit the synthesis of protein inhibitors. This compound also binds to cholesterol esters and causes lipid peroxidation, leading to cell death in cancer cells.</p>

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<p>1-Trityl-1H-imidazole-4-carbaldehyde is a phosphorane that has been synthesized in the laboratory. It is an organometallic compound with a chloroformate ligand and a mononuclear, dimethylformamide complex. 1-Trityl-1H-imidazole-4-carbaldehyde has shown to be an electrophile and binds to receptor sites with high affinity. This may be due to its ability to form hydrogen bonds with the receptor site, which often occurs for pharmacokinetic profiles.</p>

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<p>Ac-Trp-Glu-His-Asp-aldehyde is a tetrapeptide that has been shown to inhibit the activity of caspases. Caspases are proteases that play an important role in cell death by inducing apoptosis and necrosis. The structure of the Ac-Trp-Glu-His-Asp-aldehyde was determined by X-ray crystallography, revealing a hydrophobic molecule with a pseudo acid residue. This compound binds to peptides and blocks the binding site for caspase substrates, which prevents their activation. Acetylation of this compound also increases its hydrophobicity, making it more likely to bind to other molecules such as proteins or lipids.</p>

<p>2,3,5-Trichlorobenzaldehyde is a chemical compound that has been shown to have anticancer and apoptotic effects. It inhibits the growth of bacteria by chelating iron ions and inhibiting bacterial dna synthesis. 2,3,5-Trichlorobenzaldehyde has also been shown to inhibit the growth of cancer cells in culture in an experimental study. This chemical has been used as a substrate for nmr spectroscopy to study its functional groups and radical scavenging activities. 2,3,5-Trichlorobenzaldehyde can be synthesized from phenacyl chloride and benzaldehyde in the presence of hydrogen chloride gas. The carbonyl group in 2,3,5-trichlorobenzaldehyde may cause metabolic disorders such as diabetes mellitus or hyperglycemia.</p>

<p>3-Nitroisonicotinaldehyde is a kinase inhibitor that binds to the ATP binding site of receptor tyrosine kinases. It inhibits the activation of these receptors and prevents the phosphorylation of tyrosine residues on the receptor. 3-Nitroisonicotinaldehyde has been shown to inhibit VEGFR-2, ABCG2, and efflux in human cancer cells. This drug has been shown to inhibit tumor growth in mice by inhibiting angiogenesis, which is a process that involves the formation of new blood vessels from pre-existing ones. 3-Nitroisonicotinaldehyde also inhibits tumor growth by blocking the production of vascular endothelial growth factor (VEGF) from angiogenic cells.</p>

<p>Perillaldehyde is a natural compound that has been used in food and medicine for centuries. It is an antimicrobial agent with dextran sulfate, which is a sugar polymer that inhibits the growth of fungi and bacteria. Perillaldehyde also has been shown to inhibit the energy metabolism of microorganisms by decreasing ATP production. Perillaldehyde has also been shown to have genotoxic activity, as it can cause DNA strand breaks. This compound also causes oxidative stress in cells by reducing mitochondrial membrane potential and inducing reactive oxygen species (ROS). Perillaldehyde has acute toxicities, as it causes electrochemical impedance spectroscopy changes that indicate cell death.</p>

<p>Trans,cis-2,6-Nonadienal is a fatty acid derivative with an unsaturated 2,6-nonadiene structure. It is an inhibitor of the enzyme fatty acid synthase, which catalyzes the formation of long-chain polyunsaturated fatty acids. Trans,cis-2,6-Nonadienal has been shown to inhibit v79 cells and ester compounds that are used in analytical methods for measuring fatty acids. It is also able to inhibit lysine residues and it can be used as a reactive antioxidant system in mammalian cells. Trans,cis-2,6-Nonadienal has shown a profile of activities that includes inhibition at multiple endpoints involving noncompetitive inhibition as well as antioxidant activity.</p>

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<p>Benzaldehyde semicarbazone is a hydrogen bond acceptor and donor, which can be used for the synthesis of pharmaceuticals. It is also known to have significant biological activity, including anticonvulsant activity. Benzaldehyde semicarbazone has been shown to be an inhibitor of pyrazole ring formation in the reaction between 4-chlorobenzaldehyde oxime and hydrochloric acid. This inhibition may be due to its ability to act as a hydrogen bond acceptor, forming hydrogen bonds with both the carbonyl group of 4-chlorobenzaldehyde oxime and the protonated chloride ion. The mechanism is supported by kinetic studies which show that benzaldehyde semicarbazone has a much lower activation energy than the other reactants involved in the reaction.</p>

<p>2-Propyl valeraldehyde is a solvent that is used in pharmaceutical preparations and has been shown to inhibit the activity of aldehyde dehydrogenase, an enzyme that catalyzes the oxidation of alcohols and aldehydes. 2-Propyl valeraldehyde also inhibits the formation of carboxylic acids by competitive inhibition with metal ions such as zinc. The deuterium isotope effect has been used to show that 2-propyl valeraldehyde is metabolized by deuterium exchange. Mass spectrometric detection has shown that this compound contains a carbonyl group (C=O). This compound can be used as an intermediate in organic synthesis reactions, but it also has convulsant effects.</p>

<p>Doebner-Miller reaction the 4- nitrocinnamaldehyde and 2-methylaniline in concentrated HC1 give the corresponding 8-methyl-2-phenylquinoline (3: R = 4'-N02) directly. The asymmetric Friedel-Crafts-type alkylation in aqueous media reaction of 4-Nitrocinnamaldehydr with N-methyl indole using trifluoro</p>

<p>Applications 8-Nonenal is used as a reactant in the preparation of macrocyclic Z-enoates and (E,Z)- or (Z,E)-dienoates through catalytic stereoselective ring-closing metathesis.<br>References Zhang, H., et al.: JACS., 136, 16493 (2014)<br></p>

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<p>5-Nitrothiophene-2-carboxaldehyde (5NT) is a chemical compound that belongs to the class of dihedral molecules. It is commonly used as an antimicrobial agent and has been shown to have amoebicidal activity in tissue culture. 5NT also inhibits cell growth and proliferation in certain bacteria, such as Staphylococcus aureus strains, by interfering with DNA replication and protein synthesis. Although 5NT is not active against other types of bacteria, it has been shown to be effective against MRSA in laboratory studies. The biological properties of 5NT are still being studied.</p>