Antifungals
Antifungals are compounds specifically designed to stop, prevent, and eliminate the growth of fungi. In this category, you will find a wide variety of antifungal agents essential for research and therapeutic applications. These compounds are crucial in treating fungal infections and preventing their recurrence, making them vital tools in both medical and agricultural settings. Researchers and healthcare professionals can explore numerous antifungals to understand their mechanisms, optimize their efficacy, and develop new treatments to combat resistant fungal strains. The extensive selection of antifungals supports ongoing advancements in fungal research and the development of effective antifungal therapies.
Found 835 products of "Antifungals"
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(R)-(-)-2-Oxothiazolidine-4-carboxylic Acid
CAS:Controlled ProductFormula:C4H5NO3SColor and Shape:NeatMolecular weight:147.15Gibberellin A7 Methyl Ester
CAS:Controlled ProductFormula:C20H24O5Color and Shape:NeatMolecular weight:344.42-(1-(Allyloxy)-2-(1H-imidazol-1-yl)ethyl)-3,5-dichlorophenol
Controlled ProductFormula:C14H14Cl2N2O2Color and Shape:NeatMolecular weight:313.1795-Fluoro-2-mercaptobenzothiazole
CAS:Controlled Product<p>Applications 5-Fluoro-2-mercaptobenzothiazole is used as a reagent in the synthesis of [[(benzothiazolyl)thio]methyl]phenyl]furanone derivatives with agrochemical fungicidal activities.<br>References Zhao, P., et al.: Youji Huaxue, 30, 1567 (2010);<br></p>Formula:C7H4FNS2Color and Shape:NeatMolecular weight:185.24TH-302
CAS:Controlled Product<p>Applications TH-302 is a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard. Studies have shown that TH-302 treatment exhibited hypoxia-selective cytotoxicity and DNA damage in human cancer cell<br>References Meng, F. et al.: Mol. Cancer Ther., 11, 740 (2012); Liu, Q. et al.: Cancer Chemother. Pharmacol., 69, 1487 (2012); Sun, J.D. et al.: Clin. Cancer Res., 18, 758 (2012);<br></p>Formula:C9H16Br2N5O4PColor and Shape:NeatMolecular weight:449.04α-Butylpiperonyl Alcohol
CAS:Controlled Product<p>Applications Intermediate in the preparation of insecticides, fungicides, and other pesticides.<br>References Wilkinson, C., et al.: J. Agric. Food Chem., 14, 73 (1966), Zhong, W., et al.: J. Chem. Res., 6, 370 (2009),<br></p>Formula:C12H16O3Color and Shape:NeatMolecular weight:208.25cis-2-(2,4-Dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-1,3-dioxolane-4-methanol
CAS:Controlled Product<p>Applications cis-2-(2,4-Dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-1,3-dioxolane-4-methanol is an impurity in the synthesis of Itraconazole (I937500); an orally active antimycotic structurally related to Ketoconazol.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984); Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989); Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993)<br></p>Formula:C13H13Cl2N3O3Color and Shape:NeatMolecular weight:330.171-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole
CAS:Controlled Product<p>Applications 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole is an intermediate for the synthesis of Pyraclostrobin-d6 (P840402). Isotope labelled Pyraclostrobin is a fungicide for use in seed grass and food crops.<br>References Gyldenkaerne, S., et al.: Pestic Sci., 55, 1210 (1999), Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007),<br></p>Formula:C16H12ClN3O3Color and Shape:NeatMolecular weight:329.74Nitrefazole
CAS:Controlled Product<p>Applications Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase, and enzyme crucial to the metabolism of alcohol. This compound is suitable for aldehyde dehydrogenase (ALDH) related research.<br>References Klink, R. et al.: Arzneimittelforschung., 35, 1220 (1985); Koda L. et al.: Life Sci., 35, 1659 (1984);<br></p>Formula:C10H8N4O4Color and Shape:Light Yellow To YellowMolecular weight:248.195-Mercapto-1H-1,2,3-triazole Sodium Salt
CAS:Controlled Product<p>Applications 5-Mercapto-1H-1,2,3-triazole Sodium Salt is used as a reactant in the preparation of cephem derivatives as anti-Helicobacter pylori agents in relation to lability towards β-lactamase and potential for causing diarrhea.<br>References Yoshida, Y., et al.: Bioorg. Med. Chem., 8, 2317 (2000);<br></p>Formula:C2H2N3NaSColor and Shape:NeatMolecular weight:123.111-Methyl-4-nitroimidazole
CAS:Controlled Product<p>Applications 1-Methyl-4-nitroimidazole is a moiety of Azathioprine (A803350) and is predicted to have mutagenic potential.<br>References Rosenkranz, H. S., et al.: Mutat. Res-Fund. Mol. M., 251, 157 (1991); Kelly, G. E., et al.: Photochem. Photobiol., 49, 59 (1989)<br></p>Formula:C4H5N3O2Color and Shape:White To Light YellowMolecular weight:127.12-Methylbenzothiazole-6-carboxylic Acid (~90%)
CAS:Controlled Product<p>Applications 2-Methylbenzothiazole-6-carboxylic Acid (~90%) is a useful research chemical, a reagent for the synthetic studies on fungicidal agents.<br>References Saikachi, H., et al.: Yakugaku Zasshi, 78, 376 (1958); Bosco, M., et al.: Annali di Chimica, 58, 1148 (1968)<br></p>Formula:C9H7NO2SPurity:~90%Color and Shape:NeatMolecular weight:193.22(AlphaE)-2-[(6-Chloro-4-pyrimidinyl)oxy]-α-(methoxymethylene)benzeneacetic Acid Methyl Ester
CAS:Controlled Product<p>Applications (αE)-2-[(6-chloro-4-pyrimidinyl)oxy]-α-(methoxymethylene)benzeneacetic Acid Methyl Ester is an intermediate in the synthesis of Azoxystrobin (A965150), an strobilurin fungicide.<br></p>Formula:C15H13ClN2O4Color and Shape:NeatMolecular weight:320.73[1,1'-Biphenyl]-4-yl(phenyl)(1-trityl-1H-imidazol-5-yl)methanol
Controlled Product<p>Applications [1,1'-Biphenyl]-4-yl(phenyl)(1-trityl-1H-imidazol-5-yl)methanol is an intermediate in synthesizing 2-Biphenylyl Sulfate-d5 Potassium Salt (B397897), which is the isotope labelled analog of 2-Biphenylyl Sulfate Potassium Salt. 2-Biphenylyl Sulfate Potassium Salt is a derivative of 2-Phenylphenol (P335870). 2-Phenylphenol is a agriculture fungicide and is no longer used as a food additive.<br>References Scheuhly, W., et al.: Chem. Biol., 18, 1053 (2011); Singh, H.P., et al.: Food. Chem. Toxicol., 48, 1040 (2010); Gouin, T., et al.: Envro. Pollu., 165, 208 (2012);<br></p>Formula:C41H32N2OColor and Shape:NeatMolecular weight:568.706Levofloxacin
CAS:<p>Levofloxacin is a fluoroquinolone antibiotic with a mode of action that inhibits bacterial DNA gyrase and topoisomerase IV. It is used for treating bacterial infections like pneumonia and urinary tract infections.</p>Formula:C18H20FN3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:361.37 g/molBeauvericin
CAS:<p>Beauvericin is a cyclic peptide that is isolated from the fungus Fusarium. It has been shown to have antimicrobial activity against bacteria, as well as a variety of other biological properties. Beauvericin has been shown to inhibit mitochondrial membrane potential and induce toxicity in some animal models. Beauvericin also inhibits protein synthesis and causes cell death by inhibiting DNA polymerase activity. This compound is active against cancer cells, including HL-60 cells, which are derived from human lymphocytes and are used as a model for leukemia. Beauvericin can be extracted from an ETOA extract of the fungus Fusarium oxysporum; this extract has shown anti-cancer effects in vitro assays.</p>Formula:C45H57N3O9Purity:Min. 95%Molecular weight:783.95 g/mol2-Methyl-4-isothiazolin-3-one
CAS:Controlled Product<p>2-Methyl-4-isothiazolin-3-one or MIT is a powerful antimicrobial and antifungal agent which is widely used in personal care products. It is also used in industrial applications as a preservative and antifouling agent.</p>Formula:C4H5NOSPurity:Min. 96%Color and Shape:Yellow PowderMolecular weight:115.15 g/molAureothin
CAS:<p>Aureothin is a bioactive compound, classified as a polyketide antibiotic, which is derived from the culture of the bacterium Streptomyces thioluteus. This compound operates primarily through the inhibition of protein synthesis by interfering with the aminoacylation of tRNA with specific amino acids. Its mode of action disrupts cellular protein synthesis, which is essential for cell growth and function, leading to its potent antibacterial and antifungal activities.</p>Formula:C22H23NO6Purity:Min. 95%Color and Shape:PowderMolecular weight:397.42 g/molCaerulomycin A
CAS:<p>Caerulomycin A is a bioactive compound classified as a natural broad-spectrum antibiotic, which is derived from various Streptomyces species found in soil. Its mode of action involves inhibiting fungal and bacterial growth by interfering with essential cellular processes, effectively curbing the proliferation of pathogenic microorganisms. This potent molecule achieves its effects by binding to specific cellular targets, thereby disrupting cell wall synthesis and other critical metabolic pathways.</p>Formula:C12H11N3O2Purity:Min. 95%Molecular weight:229.23 g/molSordarin sodium salt
CAS:<p>Sordarin sodium salt is an antifungal agent, characterized as a semisynthetic derivative produced from the fermentation products of filamentous fungi, specifically belonging to the phylum Ascomycota. This compound exerts its effects by selectively inhibiting fungal protein synthesis. It achieves this by obstructing the function of elongation factor 2 (EF-2), an essential component of fungal ribosomal activity, thereby disrupting the translational elongation step of protein synthesis.</p>Formula:C27H39NaO8Purity:Min. 95%Molecular weight:514.58 g/molFilipin III
CAS:<p>Filipin III is a polyene macrolide antibiotic, which is extracted from Streptomyces filipinensis. Known for its unique mode of action, Filipin III interferes with cholesterol-rich membranes by binding to ergosterol and cholesterol. This interaction disrupts the membrane structure, altering membrane permeability and ultimately affecting cell viability.</p>Purity:Min. 95%Naftifine N-Oxide
CAS:<p>Naftifine N-Oxide is an antifungal agent, which is derived from synthetic chemical processes. Its structure is based on the modification of the known antifungal, naftifine, by introducing an N-oxide functional group, which may enhance certain pharmacokinetic properties. As a synthetic derivative, Naftifine N-Oxide is specifically designed to interfere with the biosynthesis of ergosterol, an essential component of fungal cell membranes. By inhibiting squalene epoxidase, an enzyme crucial to the ergosterol pathway, Naftifine N-Oxide effectively disrupts the development and maintenance of the fungal cell membrane, compromising cell integrity and leading to antifungal activity.</p>Formula:C21H21NOPurity:Min. 95%Molecular weight:303.4 g/molNeoaureothin
CAS:<p>Neoaureothin is a natural antibiotic product, which is derived from marine actinomycetes with a complex polyketide structure. Its mode of action involves the inhibition of bacterial protein synthesis by binding selectively to the ribosomal subunits, thereby obstructing the translation process in susceptible microbial strains. The specificity of its action allows it to target a broad spectrum of Gram-positive bacteria while presenting a lower risk of resistance development compared to traditional antibiotics.</p>Formula:C28H31NO6Purity:Min. 95%Molecular weight:477.5 g/mol21-Norrapamycin
CAS:<p>21-Norrapamycin is a macrocyclic lactone antibiotic, which is derived from the bacterium Streptomyces hygroscopicus. Its chemical structure is closely related to that of rapamycin, a well-known immunosuppressant. The mode of action of 21-Norrapamycin involves the inhibition of the mechanistic target of rapamycin (mTOR) signaling pathway. By binding to the FK506-binding protein 12 (FKBP12), it forms a complex that then inhibits mTOR, a crucial regulator of cell growth, proliferation, and survival.</p>Formula:C50H77NO13Purity:Min. 95%Molecular weight:900.1 g/molZelkovamycin
CAS:<p>Zelkovamycin is a novel antibacterial compound isolated from endophytic microorganisms, specifically Streptomyces sp. Endophytes are bacteria or fungi that reside within plant tissues, forming symbiotic relationships and often producing bioactive metabolites. The mode of action of Zelkovamycin involves the inhibition of bacterial cell wall synthesis, interfering with the biosynthesis pathways essential for maintaining the structural integrity and function of bacterial cell walls, particularly in Gram-positive strains.</p>Formula:C36H45N9O9SPurity:Min. 95%Color and Shape:PowderMolecular weight:779.86 g/molPropiconazole
CAS:<p>Propiconazole is a triazole fungicide with action on fungal cell membranes by inhibiting ergosterol biosynthesis and is used for controlling fungal diseases in crops and turf.</p>Formula:C15H17Cl2N3O2Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:342.22 g/molMalformin C
CAS:<p>Malformin C is a cyclic pentapeptide, which is a secondary metabolite derived from certain strains of the fungus Aspergillus. Its mode of action involves disrupting cellular processes by interfering with cell division. Specifically, it is thought to affect mitotic spindle formation, leading to abnormal cell cycle progression.</p>Formula:C23H39N5O5S2Purity:Min. 95%Color and Shape:PowderMolecular weight:529.72 g/molMiconazole
CAS:<p>Anti-fungal; sterol 14α-demethylase inhibitor</p>Formula:C18H14Cl4N2OPurity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:416.13 g/mol41-Oxo-rapamycin
CAS:<p>41-Oxo-rapamycin is a synthetic derivative of rapamycin, which is a macrocyclic lactone. It is derived from Streptomyces hygroscopicus, a gram-positive bacterium known for producing various bioactive compounds. The mode of action of 41-Oxo-rapamycin involves binding to the FK506-binding protein (FKBP12), forming a complex that subsequently inhibits the mammalian target of rapamycin (mTOR) pathway. This inhibition results in the suppression of T-cell proliferation and modulation of immune responses.</p>Formula:C51H77NO13Purity:Min. 95%Molecular weight:912.2 g/molHexamide
CAS:<p>Hexamide is a protein inhibitor.</p>Formula:C13H17NOColor and Shape:SolidMolecular weight:203.28SSF-109
CAS:<p>SSF-109 is a broad-spectrum fungicide, has protective activity against plant disease.</p>Formula:C15H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:291.78Kayahope
CAS:<p>Kayahope is a novel antifungals.</p>Formula:C15H14ClNO3SPurity:98%Color and Shape:SolidMolecular weight:323.79Fenhexamid
CAS:<p>Fenhexamid (Elevate), a sterol biosynthesis inhibitor, shows antifungal activity against the plant pathogenic fungus.</p>Formula:C14H17Cl2NO2Purity:99.56%Color and Shape:SolidMolecular weight:302.20Fosravuconazole
CAS:<p>Fosravuconazole is a ravuconazole prodrug. It has antifungal activity.</p>Formula:C23H20F2N5O5PSPurity:98%Color and Shape:SolidMolecular weight:547.47Prochloraz
CAS:<p>Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.</p>Formula:C15H16Cl3N3O2Purity:99.75% - 99.79%Color and Shape:Colorless SolidMolecular weight:376.67Antifungal agent 67
CAS:<p>Compound 9 (Antifungal agent 67), an imidazole class antifungal, exhibits efficacy against Candida and possesses a CC50 value of 33.6 μM in neonatal rat</p>Formula:C23H25ClN2O3Color and Shape:SolidMolecular weight:412.91Fuberidazole
CAS:<p>Fuberidazole is an antifungal agent.</p>Formula:C11H8N2OPurity:98.95%Molecular weight:184.19Silthiofam
CAS:<p>Silthiofam effectively combats Ggt, a wheat take-all fungus, now widely used for control in China.</p>Formula:C13H21NOSSiPurity:98%Color and Shape:SolidMolecular weight:267.46Fungicide4
CAS:<p>Fungicide4 exhibits the high activity against the P. infestans strain.</p>Formula:C14H11N3OColor and Shape:SolidMolecular weight:237.26Chitin synthase inhibitor 10
CAS:<p>Chitin Synthase Inhibitor 10: potent antifungal with 0.11 mM IC50, effective against resistant C. albicans and C. neoformans. Used in IFI research.</p>Formula:C24H23Br2N3O6Color and Shape:SolidMolecular weight:609.26Isobellidifolin
CAS:<p>Isobellidifolin, a xanthone compound, serves as a free radical scavenger and antioxidant. It exhibits a potent antifungal effect.</p>Formula:C14H10O6Color and Shape:SolidMolecular weight:274.23Cercosporamide
CAS:<p>Cercosporamide is a ATP-competitive Pkc1 kinase inhibitor (IC50 <50 nM; Ki <7 nM). It also is a unique Mnk inhibitor.</p>Formula:C16H13NO7Purity:98%Color and Shape:SolidMolecular weight:331.289-OxoOTrE
CAS:<p>9-OxoOTrE, made by oxidizing 9-HpOTrE, has antimicrobial effects on plant pathogens like bacteria and fungi.</p>Formula:C18H28O3Color and Shape:SolidMolecular weight:292.41BHBM
CAS:<p>BHBM, an acylhydrazone antifungal, halts C. neoformans growth (MIC80 = 1 μg/ml) by blocking glucosylceramide synthesis.</p>Formula:C15H13BrN2O2Color and Shape:SolidMolecular weight:333.18Ametoctradin
CAS:<p>Ametoctradin is a Qo-site inhibitor of mitochondrial respiratory complex III and is used in the study of oomycete diseases.</p>Formula:C15H25N5Purity:99.65%Color and Shape:SolidMolecular weight:275.39NB-598 hydrochloride
CAS:<p>NB-598 hydrochloride is a competitive squalene epoxidase (SE) inhibitor.</p>Formula:C27H32ClNOS2Purity:98%Color and Shape:SolidMolecular weight:486.13Antifungal agent 33
CAS:<p>Antifungal 33 (4e) strongly inhibits Candida albicans. MIC: 16 μg/ml; IC50: 0.19 μg/ml.</p>Formula:C21H14ClN5O3Color and Shape:SolidMolecular weight:419.82Antifungal agent 22
CAS:<p>Orally active antifungal D16 (IC50: 0.5 μg/mL) passes blood-brain barrier, stable, low toxicity, targets C. neoformansH99 cells.</p>Formula:C21H26Cl3NOSColor and Shape:SolidMolecular weight:446.86P163-0892
CAS:<p>P163-0892: potent, specific antifungal for Cryptococcus; moderate blood-brain barrier penetration.</p>Formula:C19H20N2O3SColor and Shape:SolidMolecular weight:356.44Antifungal agent 35
CAS:<p>Antifungal agent 35 is an effective antifungal agent that potentiates the antifungal activity of fluconazole against C. albicans.</p>Formula:C26H27BrN4O4Color and Shape:SolidMolecular weight:539.42Apogossypolone (ApoG2)
CAS:<p>Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i</p>Formula:C28H26O8Color and Shape:SolidMolecular weight:490.5Chitin synthase inhibitor 13
CAS:<p>Chitin Synthase Inhibitor 13 (compound 12g), a non-competitive antagonist of chitin synthase, demonstrates broad-spectrum antifungal activity and has an</p>Formula:C21H19N5O5SColor and Shape:SolidMolecular weight:453.47Posaconazole hydrate
CAS:<p>Posaconazole: broad-spectrum antifungal, second-gen triazole, strong C14α demethylase inhibitor (IC50: 0.25 nM).</p>Formula:C37H44F2N8O5Purity:98%Color and Shape:SolidMolecular weight:718.79S-F24
CAS:<p>S-F24 is a broad-spectrum antifungal agent that demonstrates potent inhibition of CYP3A4, with an IC50 of 0.4 μM.</p>Formula:C25H27BrF2N6OColor and Shape:SolidMolecular weight:545.42Exalamide
CAS:<p>Exalamide (2-(Hexyloxy)benzamide) is an aromatic amide with antifungal activity used in the study of dermatophytes.</p>Formula:C13H19NO2Purity:99.61%Color and Shape:White PowderMolecular weight:221.3Antifungal agent 65
CAS:<p>Compound 5d (Antifungal Agent 65) exhibits potent fungicidal activity against Fusarium oxysporum f.sp.</p>Formula:C29H29N3O2S2Color and Shape:SolidMolecular weight:515.69Chlorothalonil
CAS:<p>Chlorothalonil (DAC 2787): Broad-spectrum, efficient, low-toxicity fungicide for fruits, vegetables, rice, wheat, cotton.</p>Formula:C8Cl4N2Purity:98.01% - 98.71%Color and Shape:Colorless Crystals SolidMolecular weight:265.91Buclosamide
CAS:<p>Buclosamide is a topical antimycotic agent that can be used in dermatomycoses [1].</p>Formula:C11H14ClNO2Color and Shape:SolidMolecular weight:227.69Antifungal agent 70
CAS:<p>Antifungal Agent 70 (Compound 13), a dihydroeugenol-imidazole, exhibits efficacy against multi-resistant Candida auris with a minimum inhibitory concentration (</p>Formula:C23H25ClN2O4Color and Shape:SolidMolecular weight:428.91Tropesin
CAS:<p>Tropesin is a non-steroidal anti-inflammatory agent (NSAIA) that has inhibitory effects on the growth of Xylaria green.</p>Formula:C28H24ClNO6Color and Shape:SolidMolecular weight:505.95Rustmicin
CAS:<p>Rustmicin is a 14-membered macrolide identified as an inhibitor of plant pathogenic fungi.</p>Formula:C21H32O6Color and Shape:SolidMolecular weight:380.48CID-4785700
CAS:<p>CID-4785700 is a potent pan-GTPase inhibitor that inhibits Rab7 and inhibits the fungal histone acetyltransferase Rtt109 that binds to Asf1 and Vps75</p>Formula:C22H23ClFN3O3Purity:98.16%Color and Shape:SolidMolecular weight:431.89Antifungal agent 69
CAS:<p>Antifungal agent 69 (compound 13), a eugenol-imidazole derivative, demonstrates targeted activity against Candida albicans with a minimum inhibitory</p>Formula:C23H23ClN2O4Color and Shape:SolidMolecular weight:426.89SDH-IN-5
CAS:<p>SDH-IN-5 (compound 7d), a potent inhibitor of succinate dehydrogenase (SDH) with an IC50 of 3.293 μM, additionally demonstrates antifungal efficacy, exhibiting</p>Formula:C16H19F2N3O2Color and Shape:SolidMolecular weight:323.34Furalaxyl
CAS:<p>Furalaxyl is an fungicide of acyl amino chiral.</p>Formula:C17H19NO4Color and Shape:SolidMolecular weight:301.34Haloprogin
CAS:<p>Haloprogin is an antifungal agent used as a topical cream for the treatment of beriberi and other fungal infections.</p>Formula:C9H4Cl3IOColor and Shape:SolidMolecular weight:361.39(Z)-Fluoxastrobin
CAS:<p>(Z)-Fluoxastrobin is a fungicide that exhibits effective control of important seed and soil-borne pathogens.</p>Formula:C21H16ClFN4O5Color and Shape:SolidMolecular weight:458.83Antifungal agent 31
CAS:<p>Orally active triazole, antifungal 31 with pyrrolizinone structure, combats Candida, reduces mortality and renal infection in mice.</p>Formula:C25H22F2N6O3Color and Shape:SolidMolecular weight:492.48Antifungal agent 74
CAS:<p>Antifungal agent 74 (compound 3c), is a potent substance that exhibits excellent fungicidal activity against C.</p>Formula:C4HCl3N4SColor and Shape:SolidMolecular weight:243.5Vibunazole
CAS:<p>Vibunazole is an antifungal agent.</p>Formula:C15H20ClN3O2Color and Shape:SolidMolecular weight:309.79SC-58272
CAS:<p>SC-58272 is an inhibitor of N-myristoyltransferase (Nmt), a target for anti-fungal and anti-viral therapy.</p>Formula:C33H52N6O4Purity:98%Color and Shape:SolidMolecular weight:596.8Etisazole
CAS:<p>Etisazole is an animal antifungal agent with skin sensitizing properties to humans.</p>Formula:C9H10N2SColor and Shape:SolidMolecular weight:178.25Iodiconazole
CAS:<p>Iodiconazole, an azole antifungal, is used potentially for the treatment of fungal infection.</p>Formula:C19H19F2IN4OPurity:98%Color and Shape:SolidMolecular weight:484.28Tolciclate
CAS:<p>Tolciclate is an agent of antifungal medication.</p>Formula:C20H21NOSPurity:98%Color and Shape:SolidMolecular weight:323.45Nifuroxime
CAS:<p>Nifuroxime, an anti-infective agent, is utilized in researching fungal infections.</p>Formula:C5H4N2O4Color and Shape:SolidMolecular weight:156.1Ofurace
CAS:<p>Ofurace is a fungicide.</p>Formula:C14H16ClNO3Purity:98%Color and Shape:SolidMolecular weight:281.73Sortin2
CAS:<p>Sortin2 is a sorting inhibitor that acts upstream from the morphological marker of lateral root primordium formation, the mitotic activity.</p>Formula:C16H12ClNO5S3Purity:98%Color and Shape:SolidMolecular weight:429.92Mollugogenol A
CAS:<p>Mollugogenol A: a Gammacerane saponin from Mollugo pentaphylla with antifungal and spermatocidal properties; damages sperm membrane.</p>Formula:C30H52O4Color and Shape:SolidMolecular weight:476.73Iprovalicarb
CAS:<p>Iprovalicarb is a fungicide aimed at oomycetes.</p>Formula:C18H28N2O3Purity:98%Color and Shape:SolidMolecular weight:320.43Chitin synthase inhibitor 3
CAS:<p>Compound 2d is a potent chitin synthase inhibitor (IC50: 0.16 mM, MIC: 1 μg/mL vs. Candida albicans) with antifungal properties.</p>Formula:C20H19N3O4Color and Shape:SolidMolecular weight:365.38Antifungal agent 30
CAS:<p>Potent antifungal, works against Candida albicans (MIC: 0.03 μg/mL) & Aspergillus fumigatus (MIC: 0.5 μg/mL) via CYP51 interactions.</p>Formula:C18H14Cl2F2N2SeColor and Shape:SolidMolecular weight:446.18PD 113270
CAS:<p>PD 113,270 is an analog of the fermentation products fostriecin with antitumor activity in vitro and in vivo.</p>Formula:C19H27O8PColor and Shape:SolidMolecular weight:414.39Antibacterial agent 67
CAS:<p>Antibacterial agent 67 blocks succinate dehydrogenase more effectively than haloperidol, with IC50 of 0.03 μM vs 4.40 μM.</p>Formula:C24H15F6N5OColor and Shape:SolidMolecular weight:503.4Amorolfine
CAS:<p>Amorolfine is available in the nail lacquer and can be used to treat fungal nail infections.</p>Formula:C21H35NOColor and Shape:White To Off-White Crystalline PowderMolecular weight:317.517Benthiavalicarb isopropyl
CAS:<p>Benthiavalicarb isopropyl is a fungicide, specifically targeting downy mildew and blight.</p>Formula:C18H24FN3O3SPurity:98%Color and Shape:SolidMolecular weight:381.465-Dehydroepisterol
CAS:<p>5-Dehydroepisterol, an anti-fungal episterol form, made by C-5 sterol desaturase, turns into 24-methylenecholesterol.</p>Formula:C28H44OPurity:98%Color and Shape:SolidMolecular weight:396.65Saperconazole
CAS:<p>Saperconazole is a broad-spectrum antifungal triazole (MIC90: 0.19 mg/L).</p>Formula:C35H38F2N8O4Purity:98%Color and Shape:SolidMolecular weight:672.72Bivittoside A
CAS:<p>Bivittoside A is a non-sulfated hexoside analog obtained from Bovine sea cucumber with antifungal activity and potential antitumor activity.</p>Formula:C41H66O12Purity:98%Color and Shape:SolidMolecular weight:750.96Penflufen
CAS:<p>Penflufen, a broad-spectrum succinate dehydrogenase inhibitor (SDHI), serves effectively as a fungicide.</p>Formula:C18H24FN3OColor and Shape:SolidMolecular weight:317.4Chlordantoin
CAS:<p>Chlordantoin is an antifungal agent with the potential for vaginal candidiasis treatment.</p>Formula:C11H17Cl3N2O2SPurity:98%Color and Shape:SolidMolecular weight:347.69Inz-4
CAS:<p>Inz-4 is a fungal-selective inhibitor of mitochondrial cytochrome bc1.</p>Formula:C18H14F4N2O2Color and Shape:SolidMolecular weight:366.31Diamthazole hydrochloride
CAS:<p>Diamthazole (Dimazole) hydrochloride, an antifungal agent, is utilized in infection research.</p>Formula:C15H24ClN3OSColor and Shape:SolidMolecular weight:329.89Aliconazole
CAS:<p>Aliconazole is an imidazole derivative with antifungal activity for the study of skin infections.</p>Formula:C18H13Cl3N2Purity:99.21% - 99.79%Color and Shape:SolidMolecular weight:363.67Pyribencarb
CAS:<p>Pyribencarb, a benzylcarbamate-type fungicide, exhibits broad-spectrum activity against various plant pathogenic fungi.</p>Formula:C18H20ClN3O3Purity:99.75%Color and Shape:SolidMolecular weight:361.82Antifungal agent 59
CAS:<p>Antifungal agent 59 exhibits potent activity, reflected by MIC values ranging from 0.01 to 1 μg/mL, and inhibits the formation of fungal biofilms, while</p>Formula:C18H15BrF2N2SeColor and Shape:SolidMolecular weight:456.19Zarilamide
CAS:<p>Zarilamide disrupts microtubules, inhibiting mitosis in Phytophthora capsici zoospore cysts.</p>Formula:C11H11ClN2O2Color and Shape:SolidMolecular weight:238.67Globosuxanthone A
CAS:<p>Globosuxanthone A: a dihydroxanthenone with anticancer and antifungal properties (MIC: F. graminearum 4, F. solani 8, B. cinerea 16 μg/mL).</p>Formula:C15H12O7Color and Shape:SolidMolecular weight:304.25CYP51/HDAC-IN-1
CAS:<p>Orally active CYP51/HDAC-IN-1 dual inhibitor targets virulence factors and resistance genes; effective against Candidiasis and Cryptococcal meningitis.</p>Formula:C30H40F2N6O4Color and Shape:SolidMolecular weight:586.67Oosponol
CAS:<p>Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.</p>Formula:C11H8O5Purity:98%Color and Shape:SolidMolecular weight:220.18Ditalimfos
CAS:<p>Ditalimfos is a fungicide.</p>Formula:C12H14NO4PSColor and Shape:SolidMolecular weight:299.28β-Nor-lapachone
CAS:<p>β-Nor-lapachone is an antibiofilm agent of Candida glabrata.</p>Formula:C14H12O3Color and Shape:SolidMolecular weight:228.24Antifungal agent 46
CAS:<p>Compound 2f (Antifungal Agent 46) is a potent antifungal that inhibits Ras signaling by targeting protein farnesyltransferase [1].</p>Formula:C26H28BrF3N4O2Purity:98%Color and Shape:SolidMolecular weight:565.43Pterophyllin 2
CAS:<p>Pterophyllin 2 is an agent of natural antifungal. It also against postharvest fruit pathogenic fungi.</p>Formula:C15H12O3Purity:98%Color and Shape:SolidMolecular weight:240.25Antifungal agent 73
CAS:<p>Antifungal agent 73 (compound A32) effectively combats azole-resistant candidiasis by disrupting the fungal cell wall and membrane.</p>Formula:C21H16Cl2N2O3Color and Shape:SolidMolecular weight:415.27Pyrisoxazole
CAS:<p>Pyrisoxazole is a novel fungicide inhibitor of Sterol 14α-demethylase.</p>Formula:C16H17ClN2OColor and Shape:SolidMolecular weight:288.77Fenpropimorph
CAS:<p>Fenpropimorph is used as a small molecule fungicide.</p>Formula:C20H33NOColor and Shape:SolidMolecular weight:303.48Stemphyperylenol
CAS:<p>Stemphyperylenol: antifungal, targets Alternaria solani, MIC at 1.57 μM.</p>Formula:C20H16O6Color and Shape:SolidMolecular weight:352.3416,17-Dihydroheronamide C
CAS:<p>16,17-Dihydroheronamide C is a probe used for the analysis of the mode of action of heronamide C, which has antifungal properties.</p>Formula:C29H41NO3Color and Shape:SolidMolecular weight:451.64NSC-670224
CAS:<p>NSC-670224 blocks HDAC6 and NF-κB, is toxic to yeast at low µM concentrations, similar to tamoxifen's action.</p>Formula:C21H34Cl3NOPurity:98%Color and Shape:SolidMolecular weight:422.86Antifungal agent 36
CAS:<p>Antifungal agent 36 is a potent anti-fungal agent that shows anti-fungal activity for Basidiomycetes [1].</p>Formula:C14H21NO2Color and Shape:SolidMolecular weight:235.32DHMB
CAS:<p>DHMB (2,3-Dihydroxy-4-Methoxybenzaldehyde) exerts protective effects on intestinal epithelial cells. DHMB exhibits anti-inflammatory and antifungal capacity.</p>Formula:C8H8O4Purity:99.57%Color and Shape:SolidMolecular weight:168.15Metyltetraprole
CAS:<p>Metyltetraprole: potent fungicide, effective against Zymoseptoria, low EC50 (0.002 ppm), inhibits respiratory chain.</p>Formula:C19H17ClN6O2Color and Shape:SolidMolecular weight:396.83Succinate dehydrogenase-IN-1
CAS:<p>Succinate dehydrogenase-IN-1 (Compound 34) acts as an inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 0.94 μM and a KD of 22.4 μM. This compound also demonstrates antifungal activity, with EC50 values against Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea measured at 0.04 μM, 1.13 μM, 1.61 μM, and 1.21 μM, respectively.</p>Formula:C20H13F6N3OColor and Shape:SolidMolecular weight:425.33Antifungal agent 68
CAS:<p>Antifungal agent 68 (compound 10) effectively combats fungal infections caused by Candida and Cryptococcus gattii through the inhibition of ergosterol</p>Formula:C23H27ClN2O3Color and Shape:SolidMolecular weight:414.93Tolindate
CAS:<p>Tolindate, a potent PXR agonist, demonstrates antifungal activity and possesses an EC50 value of 8.3 µM.</p>Formula:C18H19NOSColor and Shape:SolidMolecular weight:297.41Antifungal agent 32
CAS:<p>Antifungal 32 (1a) strongly inhibits Candida albicans growth, filamentation, biofilm, and adhesion.</p>Formula:C25H28N2OColor and Shape:SolidMolecular weight:372.5Tebuconazole-d9
CAS:<p>Tebuconazole-d9 is a GC/LC-MS standard for quantifying the triazole fungicide tebuconazole, affecting seed/foliar fungi and androgen receptors.</p>Formula:C16H13ClD9N3OColor and Shape:SolidMolecular weight:316.87Justicidin B
CAS:<p>Justicidin B: anticancer, proapoptotic, inhibits bone resorption & platelets, antiviral, fungicidal, antiprotozoal.</p>Formula:C21H16O6Color and Shape:SolidMolecular weight:364.35(-)-Ketoconazole
CAS:<p>(-)-Ketoconazole is a potential mitochondrial CYP24A1 inhibitor and has antifungal activity against Aspergillus fumigatus.</p>Formula:C26H28Cl2N4O4Purity:98%Color and Shape:SolidMolecular weight:531.43Diamthazole
CAS:<p>Diamthazole (Dimazole) is an antifungal agent that can be used in the infection research[1].</p>Formula:C15H23N3OSColor and Shape:SolidMolecular weight:293.43Diethofencarb
CAS:<p>Diethofencarb: a fungicide effective against Botrytis cinerea and resistant Botryis strains.</p>Formula:C14H21NO4Color and Shape:SolidMolecular weight:267.32BI-10
CAS:<p>BI-10, paired with fluconazole, hinders fungal growth, increases ROS, decreases MMP, and changes membrane permeability.</p>Formula:C23H17BrN2OColor and Shape:SolidMolecular weight:417.3Antifungal agent 2
CAS:<p>Antifungal agent 2 suppresses growth of Cryptococcus, Candida, Aspergillus at ≥0.5 μg/mL.</p>Formula:C19H11Br2F3N4O2Purity:98%Color and Shape:SolidMolecular weight:544.12FBA-IN-1
CAS:<p>FBA-IN-1 (2a11) is the first covalent, allosteric CaFBA inhibitor, effective against Azole-resistant strains with a MIC 80 of 1 μg/mL.</p>Formula:C15H13NOSePurity:98.79%Color and Shape:SolidMolecular weight:302.23Lipoxamycin
CAS:<p>Lipoxamycin is an inhibitor of serine palmitoyl-transferase.</p>Formula:C19H36N2O5Purity:98%Color and Shape:SolidMolecular weight:372.541F5
CAS:<p>41F5: Anti-fungal with MIC50 0.4-0.8 μM and IC50 0.87 μM against Histoplasma; 62x more selective for yeast vs host cells.</p>Formula:C21H22N2OSColor and Shape:SolidMolecular weight:350.48Flutolanil
CAS:<p>Flutolanil: a fungicide targeting R. solani in rice, toxic to zebrafish.</p>Formula:C17H16F3NO2Color and Shape:SolidMolecular weight:323.31Debneyol
CAS:<p>Debneyol exhibits more potent fungicidal activity than validamycin.</p>Formula:C15H26O2Color and Shape:SolidMolecular weight:238.371-(6-Amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7- quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
CAS:<p>1-(6-Amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7-quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is a fluoroquinolone antibiotic, engineered through synthetic chemistry. It is derived from chemical sources involving complex organic synthesis, highlighting its intricate molecular architecture. Its mode of action is distinctive, as it inhibits bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription. This interference with bacterial DNA processes results in bactericidal effects, effectively eliminating susceptible bacterial strains.</p>Formula:C36H24Cl2F6N8O8Purity:Min. 95%Molecular weight:881.52 g/molRilopirox
CAS:<p>Rilopirox is a synthetic fungicidal antimycotic with hydrophobic characteristics.</p>Formula:C19H16ClNO4Purity:99.17% - 99.72%Color and Shape:SolidMolecular weight:357.79Pramiconazole
CAS:<p>Pramiconazole (R126638), an oral antifungal, treats dermatophyte and yeast infections in seborrheic dermatitis.</p>Formula:C35H39F2N7O4Purity:98.59% - 99.41%Color and Shape:SolidMolecular weight:659.73Flutrimazole
CAS:<p>Flutrimazole: a dual-action imidazole with anti-inflammatory and antifungal effects; ideal for topical use due to limited skin penetration.</p>Formula:C22H16F2N2Purity:98.56%Color and Shape:SolidMolecular weight:346.37ME1111
CAS:<p>ME1111, a succinate dehydrogenase inhibitor of Trichophyton species, serves as an antifungal agent effective against dermatophytes.</p>Formula:C12H14N2OPurity:99.45%Color and Shape:SolidMolecular weight:202.25Micafungin FR-179642 impurity (acid)
CAS:<p>Micafungin is an antifungal drug that inhibits the synthesis of ergosterol, a vital component of fungal cell membranes. It is a cyclic peptide with a lipophilic fatty acid chain that has been modified to allow penetration into cells. Micafungin is active against Candida and Aspergillus species and has shown activity against some strains of Cryptococcus neoformans. The MIC (minimum inhibitory concentration) for this drug ranges from 0.06 to 1 microgram/mL, depending on the bacterial strain being tested. Micafungin FR-179642 impurity (acid) is an impurity in micafungin that can be present as trace amounts in the final product and may contribute to hemolytic activity. This impurity is formed by hydrolysis during the synthesis process.</p>Formula:C35H52N8O20SPurity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:936.9 g/molPC945
CAS:<p>PC945 (Opelconazole) is an antifungal compound that inhibits CYP51A/CYP51B and can be used to study fungal infections of the lungs.</p>Formula:C38H37F3N6O3Purity:98.89% - 99.37%Color and Shape:SolidMolecular weight:682.73Dihydropenicillin F potassium
CAS:<p>Dihydropenicillin F potassium is a novel antibiotic compound, which is semisynthetic in nature, derived from the penicillin family. It is sourced through the modification of natural penicillins, bringing about enhanced stability and efficacy against certain resistant bacterial strains. The mode of action involves the inhibition of bacterial cell wall synthesis, primarily targeting the penicillin-binding proteins (PBPs). This disruption consequently leads to cell lysis and the eventual bacterial death.</p>Formula:C14H22N2O4S•KPurity:Min. 95%Molecular weight:353.5 g/molN,O-Diacetyltyramine
CAS:<p>N,O-Diacetyltyramine, isolated from the actinomycete Pseudonocardia endophytica VUK-10, exhibits both antibacterial activity against Gram-positive and Gram-negative bacteria, alongside fungi, and demonstrates cytotoxicity towards MDA-MB-231, HeLa, MCF-7, and OAW-42 cells [1].</p>Formula:C12H15NO3Color and Shape:SolidMolecular weight:221.25Antifungal agent 24
CAS:<p>Antifungal agent 24 (Compound 6) is an antifungal agent that inhibits Candida albicans (MIC: 0.03 μg/ml).</p>Formula:C24H18F2N4OColor and Shape:SolidMolecular weight:416.42FR194738 free base
CAS:<p>FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. </p>Formula:C27H37NO2SPurity:99.13%Color and Shape:SolidMolecular weight:439.65Laxifloran
CAS:<p>Laxifloran possesses antibacterial and antifungal properties.</p>Formula:C17H18O5Color and Shape:SolidMolecular weight:302.32Azaconazole
CAS:<p>Azaconazole, an agricultural fungicide, is used for controlling powdery mildew on crops and bean rust.</p>Formula:C12H11Cl2N3O2Color and Shape:SolidMolecular weight:300.14Antifungal agent 50
CAS:<p>Antifungal agent 50 exhibits minimum inhibitory concentrations (MICs) ranging from less than 0.063 to 1 μg/mL [1].</p>Formula:C25H20ClN5O2SColor and Shape:SolidMolecular weight:489.98Alteconazole
CAS:<p>Alteconazole is an antifungal drug.</p>Formula:C17H12Cl3N3OPurity:98%Color and Shape:SolidMolecular weight:380.66FT895
CAS:<p>FT895 is a selective and potent HDAC11 inhibitor with antifungal and antitumor activity that inhibits HDAC11 expression and limits EV71 replication in vitro.</p>Formula:C16H15F3N4O2Purity:98.95% - >99.99%Color and Shape:SolidMolecular weight:352.31Inz-1
CAS:<p>Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.</p>Formula:C16H14N2O2Purity:99.55% - 99.88%Color and Shape:SolidMolecular weight:266.29PF-184563
CAS:<p>PF-184563 is an effective and selective non-peptide antagonist of the V1a receptor with oral activity, suitable for studying Raynaud's disease dysmenorrhoea.</p>Formula:C21H23ClN6Purity:99.67%Color and Shape:SolidMolecular weight:394.9Methyl 3,4-dimethoxycinnamate
CAS:<p>Methyl 3,4-dimethoxycinnamate impedes uredospore germination and concurrently inhibits global DNA methylation in Hep3B cells [1] [2].</p>Formula:C12H14O4Color and Shape:SolidMolecular weight:222.246-Chloro-7-deazapurine-β-D-riboside
CAS:<p>6-Chloro-7-deazapurine-β-D-riboside shows antifungal activity.</p>Formula:C11H12ClN3O4Purity:98.26%Color and Shape:SolidMolecular weight:285.68Icofungipen
CAS:<p>Icofungipen is an oral antifungals with active against Candida species.</p>Formula:C7H11NO2Purity:98%Color and Shape:SolidMolecular weight:141.17APX001
CAS:<p>APX001 is a prodrug of APX-001A. APX001 is the first-in-class inhibitor of the fungal protein Gwt1.</p>Formula:C22H21N4O6PPurity:98%Color and Shape:SolidMolecular weight:468.4VT-1598
CAS:<p>VT-1598 is a novel, selective, orally active fungal CYP51 inhibitor. VT-1598 exhibits antifungal effects against Candida albicans.</p>Formula:C31H20F4N6O2Color and Shape:SolidMolecular weight:584.52Antifungal agent 26
CAS:<p>Pradimicin A derivative 26 exhibits antifungal, antiviral, and antiparasitic properties by attaching to d-mannose (Man)-rich glycans in pathogenic organisms [1</p>Formula:C40H45N3O18Color and Shape:SolidMolecular weight:855.79Loflucarban
CAS:<p>Loflucarban (Fluonilid) is an antimycotic compoud.</p>Formula:C13H9Cl2FN2SPurity:98.08% - 98.15%Color and Shape:SolidMolecular weight:315.19TMV-IN-5
CAS:<p>TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding</p>Formula:C22H23N3SColor and Shape:SolidMolecular weight:361.5Antifungal agent 66
CAS:<p>Antifungal agent 66 (compound 10) exhibits broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and significant inhibitory effects on</p>Formula:C19H25ClO6Color and Shape:SolidMolecular weight:384.85Antifungal agent 48
CAS:<p>Antifungal agent 48 (Example 308), active against Cryptococcus neoformans, exhibits a minimum inhibitory concentration (MIC) value of 11 μM [1].</p>Formula:C13H10O4SColor and Shape:SolidMolecular weight:262.28Eucalyptacid A
CAS:<p>Eucalyptacid A, a metabolite with antifungal properties, demonstrates efficacy against Alternaria solani, displaying minimum inhibitory concentrations (MIC)</p>Formula:C17H32O5Color and Shape:SolidMolecular weight:316.43Prochloraz manganese
CAS:<p>Prochloraz manganese, an antifungal agent utilized in the agricultural sectors [1], serves to protect crops by inhibiting fungal growth.</p>Formula:C60H64Cl14MnN12O8Color and Shape:SolidMolecular weight:1632.51MoTPS1-IN-1
CAS:<p>MoTPS1-IN-1 is a potent MoTPS1 inhibitor with antifungal anti-inflammatory activity that acts through interaction with Glu396 study ulcerative colitis.</p>Formula:C23H27F3N2O4Purity:99.28%Color and Shape:SoildMolecular weight:452.47Verazine
CAS:<p>(-)-Verazine is an antifungal agent isolated from the dried roots and rhizome of Veratrum maackii Regel, which induces DNA damage in the cerebellum and cerebral</p>Formula:C27H43NOColor and Shape:SolidMolecular weight:397.642-Dodecanol
CAS:<p>2-Dodecanol suppresses both hyphal development and SIR2 gene expression in Candida albicans [1].</p>Formula:C12H26OColor and Shape:SolidMolecular weight:186.33Antifungal agent 49
CAS:<p>Antifungal agent 49 (Example 112) exhibits activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM [1].</p>Formula:C15H12O4Color and Shape:SolidMolecular weight:256.25APX2039
CAS:<p>APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity</p>Formula:C20H15FN4O2Purity:98.72% - 99.07%Color and Shape:SolidMolecular weight:362.36Fenpropidin
CAS:<p>Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.</p>Formula:C19H31NPurity:98.58% - 99.54%Color and Shape:SolidMolecular weight:273.46Y18501
CAS:<p>Y18501, an oxysterol-binding protein (OSBPI) inhibitor structurally akin to Oxathiapiprolin, demonstrates potent inhibition against Phytophthora spp.</p>Formula:C27H26F2N6O2SColor and Shape:SolidMolecular weight:536.6Dihydroaltenuene B
CAS:<p>Dihydroaltenuene B inhibits mushroom tyrosinase (IC50: 38.33µM) and binds His244, Met280, Gly281 via hydrogen bonds.</p>Formula:C15H18O6Color and Shape:SolidMolecular weight:294.3HDAC/HSP90-IN-3
CAS:<p>HDAC/HSP90-IN-3, a dual inhibitor targeting fungal Hsp90 (IC50: 0.83 μM) & HDAC (IC50: 0.91 μM), counters azole-resistant C. albicans.</p>Formula:C26H33N5O6Color and Shape:SolidMolecular weight:511.57Antiproliferative agent-18
CAS:<p>Compound 5k (Antiproliferative Agent-18) is an antiproliferative agent that exhibits moderate antibacterial and antifungal activities [1].</p>Formula:C26H27FN2OSColor and Shape:SolidMolecular weight:434.57Antifungal agent 77
CAS:<p>Antifungal agent 77 (Compound 13h) exhibits not only antifungal properties, but also effective insecticidal activity against Mythimna separata, Helicoverpa</p>Formula:C21H18FN5O2Color and Shape:SolidMolecular weight:391.4Chitin synthase inhibitor 14
CAS:<p>Chitin Synthase Inhibitor 14 (compound 4n), a potent chitin synthase (CHS) inhibitor, exhibits antifungal activity and is effective against drug-resistant</p>Formula:C25H26ClN5O5Color and Shape:SolidMolecular weight:511.96Orysastrobin
CAS:<p>Orysastrobin, a "quinone outside inhibitor" (QoI) fungicide, demonstrates outstanding efficacy in controlling rice leaf and panicle blast as well as sheath</p>Formula:C18H25N5O5Color and Shape:SolidMolecular weight:391.42Zoxamide
CAS:<p>Zoxamide (RH-7281) is an oomycete-specific fungicide that impedes nuclear division in Phytophthora capsici germlings and disrupts the microtubule cytoskeleton [</p>Formula:C14H16Cl3NO2Color and Shape:SolidMolecular weight:336.64Inz-5
CAS:<p>Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance.</p>Formula:C18H14F4N6Color and Shape:SolidMolecular weight:390.34Econazole
CAS:<p>Econazole is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal skin infections like athlete's foot and ringworm.</p>Formula:C18H15Cl3N2OPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:381.68 g/molFengycin
CAS:<p>Fengycin is a cyclic lipopeptide from Bacillus subtilis acts as a biosurfactant and antifungal. As a fungicide, it has a mode of action that involves the formation of ion channels in the fungal lipid membrane, leading to membrane leakage This activity is negatively correlated to cholesterol levels, and may explain why mammalian cells, with higher cholesterol present, are not sensitive to fengycin.</p>Formula:C72H110N12O20Purity:Min. 90 Area-%Color and Shape:PowderMolecular weight:1,463.71 g/mol2,4′-Dichloroacetanilide
CAS:<p>2,4′-Dichloroacetanilide (2-chloro-N-(4-chlorophenyl)acetamide) has antifungal activity and inhibits T. asteroides with a MIC value of 6.25 μg/mL.</p>Formula:C8H7Cl2NOPurity:99.36%Color and Shape:SolidMolecular weight:204.05Fosmanogepix
CAS:<p>Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.</p>Formula:C22H21N4O6PPurity:98%Color and Shape:SolidMolecular weight:468.40Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Formula:C24H26N4Se2Color and Shape:SolidMolecular weight:528.41CDA-IN-4
CAS:<p>CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.</p>Formula:C10H9BrN4O2SColor and Shape:SolidMolecular weight:329.17HDAC-IN-87
CAS:<p>HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.</p>Formula:C13H7F5N4O2SColor and Shape:SolidMolecular weight:378.277Chitin synthase inhibitor 9
<p>CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.</p>Formula:C24H25N3O6Color and Shape:SolidMolecular weight:451.47Antifungal agent 28
<p>Antifungal 28 disrupts Candida, hits fluconazole-resistant strains, and inhibits biofilms.</p>Formula:C22H29N5OSColor and Shape:SolidMolecular weight:411.56AnCDA-IN-1
CAS:<p>AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.</p>Formula:C16H13ClN4O2Color and Shape:SolidMolecular weight:328.753Antifungal agent 17
<p>Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).</p>Formula:C18H16Br2O2Color and Shape:SolidMolecular weight:424.13Antifungal agent 100
CAS:<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Formula:C23H21N3O4SColor and Shape:SolidMolecular weight:435.5Antibacterial agent 188
CAS:<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Formula:C12H10N4SColor and Shape:SolidMolecular weight:242.3HSP90-IN-9
<p>HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.</p>Color and Shape:SolidIsopyrazam
CAS:<p>Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.</p>Formula:C20H23F2N3OColor and Shape:SolidMolecular weight:359.41Antifungal agent 127
CAS:<p>Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.</p>Formula:C13H12ClN3OColor and Shape:SolidMolecular weight:261.707Antifungal agent 125
CAS:<p>Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.</p>Formula:C13H10BrNO4SColor and Shape:SolidMolecular weight:356.192Hyalodendrin
CAS:<p>Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.</p>Formula:C14H16N2O3S2Color and Shape:SolidMolecular weight:324.42WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Formula:C24H23F6N5O5Purity:99.52%Color and Shape:SoildMolecular weight:575.46CDA-IN-3
CAS:<p>CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.</p>Formula:C16H27N3O3S2Color and Shape:SolidMolecular weight:373.534CDA-IN-2
CAS:<p>CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.</p>Formula:C17H16N2O7Color and Shape:SolidMolecular weight:360.318CDA-IN-1
CAS:<p>CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.</p>Formula:C15H14N2O6Color and Shape:SolidMolecular weight:318.281Chitin synthase inhibitor 8
<p>Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infections</p>Formula:C23H23N3O5Color and Shape:SolidMolecular weight:421.45Furametpyr
CAS:<p>Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.</p>Formula:C17H20ClN3O2Purity:98%Color and Shape:SolidMolecular weight:333.81Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Formula:C20H16F3N7O2S2Color and Shape:SolidMolecular weight:507.51Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Formula:C21H19F2N7O3S2Color and Shape:SolidMolecular weight:519.55
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