Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,524 products)
- Apoptosis(5,793 products)
- Cell Cycle/Checkpoint(4,452 products)
- Chromatin/Epigenetics(2,242 products)
- Cytoskeletal Signaling(1,382 products)
- DNA Damage/DNA Repair(2,826 products)
- Endocrinology/Hormones(3,507 products)
- Enzyme(3,640 products)
- GPCR/G-Protein(8,333 products)
- Immunology and Inflammation(3,527 products)
- Influenza Virus(296 products)
- JAK/STAT signaling(404 products)
- MAPK Signaling(1,203 products)
- Membrane Transporter/Ion Channel(2,792 products)
- Metabolism(9,449 products)
- Microbiology/Virology(6,981 products)
- Neuroscience(9,926 products)
- Other Inhibitors(37,921 products)
- Oxidation-Reduction(41 products)
- PI3K/Akt/mTOR Signaling(1,400 products)
- Proteases/Proteasome(1,597 products)
- Stem Cell and Derivatives(830 products)
- Tyrosine Kinase/Adaptors(2,015 products)
- Ubiquitination(1,650 products)
Show 16 more subcategories
Found 66639 products of "Inhibitors"
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H 218-54
CAS:<p>H 218-54 is a renin inhibitor.</p>Formula:C37H56N2O5SColor and Shape:SolidMolecular weight:640.92COX-2/PI3K-IN-2
<p>COX-2/PI3K-IN-2 (5f): anti-inflammatory & anti-cancer, selectively inhibits COX-2 (Ki=3.02nM), potently blocks PI3K (IC50=2.78nM).</p>Formula:C16H17N5O2Color and Shape:SolidMolecular weight:311.34Revamilast
CAS:<p>Revamilast, also known as GRC4039, is a phosphodiesterase IV inhibitor for potentially treating of asthma and rheumatoid arthritis</p>Formula:C18H9Cl2F2N3O4Color and Shape:SolidMolecular weight:440.18Triciferol
CAS:<p>Triciferol is a VDR agonist and HDAC antagonist with 1,25D-like potency, affecting gene targets and tubulin, and shows anti-cancer effects in vitro. IC50=87nM.</p>Formula:C26H39NO4Color and Shape:SolidMolecular weight:429.591Alkyne-probe 1
<p>Alkyne-probe 1 is usually used as an Alkyne-labeled fluorescent or chemical probe.</p>Formula:C14H23N5O2Purity:98%Color and Shape:SolidMolecular weight:293.36Anticancer agent 53
CAS:<p>Anticancer agent 53 exhibits potent in vitro cytotoxicity, triggers apoptosis, halts S/G2/M cycle, and has antitumor effects without toxicity.</p>Formula:C31H25FN4O6SColor and Shape:SolidMolecular weight:600.62Lavendomycin
CAS:<p>Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.</p>Formula:C29H50N10O8Color and Shape:SolidMolecular weight:666.77Anticancer agent 142
CAS:<p>Compound 142 (also known as Compound 235) is a PTPN inhibitor with potential applications in cancer research [1].</p>Formula:C13H14BrF2N2O7PS2Purity:98%Color and Shape:SolidMolecular weight:523.26GLP-1R agonist 8
CAS:<p>GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).</p>Formula:C33H32N4O5Color and Shape:SolidMolecular weight:564.63STING agonist-7
<p>STING agonist-7 is an agonist of non-nucleotide STING that binds selectively to mouse STING but not human STING [1].</p>Formula:C17H12N4O4Color and Shape:SolidMolecular weight:336.3AX15910
<p>AX15910 is a potent inhibitor of BRD4 and ERK5.</p>Formula:C32H38N6O3Color and Shape:SolidMolecular weight:554.7RET-IN-1
CAS:<p>RET-IN-1 is a RET kinase inhibitor (IC50s: 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively).</p>Formula:C29H31N9O3Purity:98%Color and Shape:SolidMolecular weight:553.61MDL-100240
CAS:<p>MDL-100240 inhibits ACE/neprilysin, effective against hypertension-induced heart/vascular changes.</p>Formula:C26H28N2O5SPurity:98%Color and Shape:SolidMolecular weight:480.58Onfasprodil
CAS:<p>Onfasprodil, NR2B inhibitor & GABA regulator, potential for Alzheimer's research. (Patent CN111481543A)</p>Formula:C20H23FN2O3Color and Shape:SolidMolecular weight:358.41Lepidozin G
<p>Lepidozin G blocks cancer growth (IC50=4.2-5.7μM) and triggers apoptosis in PC-3 cells via mitochondria.</p>Formula:C30H48O4Color and Shape:SolidMolecular weight:472.7L-365260 hemihydrate
<p>L-365260 hemihydrate: selective oral CCK-B/gastrin blocker, Ki=1.9/2.0 nM, competes with guinea pig receptors.</p>Formula:C24H24N4O3Color and Shape:SolidMolecular weight:407.47JH295 hydrate
<p>JH295 hydrate: potent, irreversible Nek2 inhibitor (IC50 = 770 nM), selective, doesn't target Cdk1, Aurora B or Plk1.</p>Formula:C18H18N4O3Color and Shape:SolidMolecular weight:338.36XY153
<p>XY153 (8l) is a BD2 selective BET inhibitor targeting BRD4, 3 & 2 with IC50s: 0.79, 5.31 & 5.09 nM, useful in acute myeloid leukemia & cancer research.</p>Formula:C33H34FN3O4Color and Shape:SolidMolecular weight:555.64MI-1481
CAS:<p>MI-1481: potent MML1 inhibitor, IC50 3.6 nM; disrupts menin-MLL1, active in MLL leukemia.</p>Formula:C29H30F3N7O2SPurity:98%Color and Shape:SolidMolecular weight:597.65UH 301
CAS:<p>UH 301 is a 5-HT1A receptor antagonist.</p>Formula:C16H24FNOColor and Shape:SolidMolecular weight:265.37P-gp modulator 2
<p>P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic P-glycoprotein (P-gp) modulator.</p>Formula:C22H20BrN3O4Color and Shape:SolidMolecular weight:470.32NK-1 Antagonist 1
CAS:<p>NK-1 Antagonist 1 is a NK-1 receptor antagonist.</p>Formula:C25H23F6N5O2Purity:98%Color and Shape:SolidMolecular weight:539.47PptT-IN-1
<p>PptT-IN-1, a potent PptT inhibitor (IC50: 2.8 μM), shows promise for tuberculosis research.</p>Formula:C18H29N5O2Color and Shape:SolidMolecular weight:347.46Monoamine Oxidase B inhibitor 1
<p>Potent, selective MAO-B inhibitor; reversible; oral; crosses BBB; IC50=0.02 nM; potential for Parkinson's research.</p>Formula:C18H15FO3Color and Shape:SolidMolecular weight:298.31PKCiota-IN-1
CAS:<p>PKCiota-IN-1: Strong PKC-ι inhibitor (IC50=2.7 nM); also blocks PKC-α/ε (IC50s=45/450 nM).</p>Formula:C25H22FN5OColor and Shape:SolidMolecular weight:427.47TCMDC-135051 TFA (2413716-15-9 free base)
<p>TCMDC-135051 TFA is a highly selective and potent inhibitor of protein kinase PfCLK3.</p>Formula:C31H34F3N3O5Purity:98%Color and Shape:SolidMolecular weight:585.61Topoisomerase I inhibitor 8
CAS:<p>Topoisomerase I inhibitor 8, a hexacyclic analogue of camptothecin, is also a potent inhibitor of topoisomerase I and is toxic to tumour cells.</p>Formula:C24H21FN2O4Color and Shape:SolidMolecular weight:420.43Steroid sulfatase/17β-HSD1-IN-3
<p>Steroid sulfatase/17β-HSD1-IN-3 (compound 19) is a dual inhibitor of steroid sulfatase (STS) and 17β-hydroxysteroid dehydrogenase type 1 (17β HSD1).</p>Formula:C19H17ClN2O5SColor and Shape:SolidMolecular weight:420.87BAY-091
CAS:<p>BAY-091 is a novel potent and highly selective PIP4K2A kinase inhibitor.</p>Formula:C26H21FN4O2Purity:97.66% - 99.23%Color and Shape:SoildMolecular weight:440.47BPN-15606 besylate
<p>BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).</p>Formula:C29H29FN6O4SColor and Shape:SolidMolecular weight:576.64SML-10-70-1
CAS:<p>SML-10-70-1 is a Novel Active Site Inhibitor of Oncogenic K-Ras G12C.</p>Formula:C25H42ClN7O13P2Color and Shape:SolidMolecular weight:746.04Chk1-IN-5
CAS:<p>Chk1-IN-5 inhibits Chk1, blocking phosphorylation and suppressing colon cancer growth.</p>Formula:C18H18FN7O2Color and Shape:SolidMolecular weight:383.38CBP/p300-IN-18
<p>CBP/p300-IN-18 (compound 8) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.056 μM) and LK2 H3K27 (IC50: 0.46 μM).</p>Formula:C25H27FN4O3Color and Shape:SolidMolecular weight:450.51ZK159222
CAS:<p>ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.</p>Formula:C32H48O5Purity:98%Color and Shape:SolidMolecular weight:512.72YW3-56
CAS:<p>YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.</p>Formula:C27H32ClN5O2Color and Shape:SolidMolecular weight:494.03Carbonic anhydrase inhibitor 4
<p>CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.</p>Formula:C21H18N2O4SColor and Shape:SolidMolecular weight:394.44LY309887
CAS:<p>LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.</p>Formula:C19H23N5O6SColor and Shape:SolidMolecular weight:449.48BAY 38-7271
CAS:<p>BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) & 5.96 nM (CB2).</p>Formula:C20H21F3O5SPurity:98%Color and Shape:SolidMolecular weight:430.44Cilengitide hydrochloride
CAS:<p>Cilengitide hydrochloride is a salt that may combat cancer by blocking specific integrins, disrupting cell interactions and angiogenesis.</p>Formula:C27H41ClN8O7Color and Shape:SolidMolecular weight:625.12Tubulin polymerization-IN-35
<p>Tubulin-IN-35 inhibits oxazolylisoindole microtubule formation, targeting VL51 marginal zone lymphoma.</p>Formula:C31H35N3O5Color and Shape:SolidMolecular weight:529.63Imolamine hydrochloride
CAS:<p>Imolamine hydrochloride is a blood platelet aggregation antagonist.</p>Formula:C14H21ClN4OColor and Shape:SolidMolecular weight:296.80Ornoprostil
CAS:<p>Ornoprostil, a prostaglandin E1 analogue, acts as a mucosal protectant.</p>Formula:C23H38O6Purity:98%Color and Shape:SolidMolecular weight:410.54ATR-IN-12
<p>ATR-IN-12, a potent ATR kinase inhibitor with IC50 of 0.007 μM, shows promise for drug development.</p>Formula:C22H27N5O3SColor and Shape:SolidMolecular weight:441.55Chitin synthase inhibitor 8
<p>Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infections</p>Formula:C23H23N3O5Color and Shape:SolidMolecular weight:421.45K252d
CAS:<p>K252d: indolocarbazole alkaloid in Nocardiopsis; inhibits PKC in rat brain and bovine heart phosphodiesterase.</p>Formula:C26H23N3O5Color and Shape:SolidMolecular weight:457.48CDK1-IN-3
<p>CDK1-IN-3 is a selective inhibitor targeting CDK1 (36.8 nM), CDK2 (305.17 nM), CDK5 (369.37 nM); used in cancer research.</p>Formula:C28H25ClF3N5O2Color and Shape:SolidMolecular weight:555.98TD-0212 TFA
CAS:<p>TD-0212 TFA is an oral AT1 receptor antagonist & NEP inhibitor with pKi 8.9 & pIC50 9.2.</p>Formula:C30H35F4N3O6SPurity:98%Color and Shape:SolidMolecular weight:641.67RGB-286638
CAS:<p>RGB-286638 inhibits multiple CDKs and GSK-3β, TAK1, Jak2, MEK1 with IC50s as low as 1-54 nM.</p>Formula:C29H37Cl2N7O4Color and Shape:SolidMolecular weight:618.55Nenocorilant
CAS:<p>Nenocorilant (Relacorilant) is an orally active glucocorticoid receptor (GR) antagonist (Ki: 0.15 nM). Nenocorilant can be used to study tumours.</p>Formula:C26H21F4N7O3SColor and Shape:SolidMolecular weight:587.55Oral antiplatelet agent 1
CAS:<p>Oral antiplatelet agent 1 is a potent antiplatelet agent with an IC50 of 2.94 μM in vitro.</p>Formula:C23H24N4O5SPurity:98%Color and Shape:SolidMolecular weight:468.53Anticancer agent 12
<p>Anticancer agent 12 shows cytotoxic activity in malignant cells with no hepatotoxicity.</p>Formula:C16H17BrN4O2SColor and Shape:SolidMolecular weight:409.32R,4S-Sacubitril
CAS:<p>2R,4S-Sacubitril (Sacubitril Enantiomer) is the impurity of Sacubitril which is a neprilysin inhibitor.</p>Formula:C24H28NO51CaPurity:98%Color and Shape:SolidMolecular weight:430.49D4R antagonist-1
<p>Potent, selective D4R antagonist; IC50 = 6.87 µM; potential in Parkinson’s disease research.</p>Formula:C21H25F2NO2Color and Shape:SolidMolecular weight:361.43METTL3-IN-2
CAS:<p>METTL3-IN-2, a potent METTL3 inhibitor, exhibits an IC50 value of 6.1 nM, effectively impairing the proliferation of Caov3 cancer cells.</p>Formula:C25H26N8OColor and Shape:SolidMolecular weight:454.53Sesamodil
CAS:<p>Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.</p>Formula:C29H32N2O6SPurity:98.58% - 99.01%Color and Shape:SolidMolecular weight:536.64PptT-IN-2
<p>PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.</p>Formula:C22H29N5O2Color and Shape:SolidMolecular weight:395.5Enpp-1-IN-11
<p>Enpp-1-IN-11 inhibits ENPP1 with a 45 nM Ki, is plasma stable, and has low clearance in human/mouse livers, potentially aiding cancer research.</p>Formula:C15H15N5O3SColor and Shape:SolidMolecular weight:345.38PD 140376
CAS:<p>PD 140376: Selective CCK-B/gastrin receptor antagonist radioligand for guinea pig stomach & brain.</p>Formula:C33H40N4O5Purity:98%Color and Shape:SolidMolecular weight:572.69Cap-dependent endonuclease-IN-17
CAS:<p>CEN inhibitor IN-17 targets influenza A/H3N2; IC50: 1.29 μM. From patent CN112898346A, DSC701.</p>Formula:C24H20F2N3O7PSColor and Shape:SolidMolecular weight:563.47BACE1-IN-5
CAS:<p>BACE1-IN-5 inhibits BACE1 (IC50: 9.1 nM) & Aβ production (IC50: 0.82 nM), enhances hERG inhibition & P-gp efflux.</p>Formula:C18H16F5N5O2SPurity:98%Color and Shape:SolidMolecular weight:461.41Mu opioid receptor antagonist 2
<p>Compound 25: potent, selective MOR antagonist, crosses blood-brain barrier (Ki: 0.37 nM, EC50: 0.44 nM), for OUD research.</p>Formula:C25H28N2O4SColor and Shape:SolidMolecular weight:452.57EGFR-IN-34
<p>EGFR-IN-34 is a low-toxicity, acrylamide derivative antitumor agent that is a potent inhibitor of EGFR.</p>Formula:C26H27ClN6O2Color and Shape:SolidMolecular weight:490.98BRD5631
CAS:<p>BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway.</p>Formula:C30H35N3O4Purity:98%Color and Shape:SolidMolecular weight:501.62Unoprostone
CAS:<p>Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension.</p>Formula:C22H38O5Purity:98%Color and Shape:SolidMolecular weight:382.53Hsp90-IN-16
<p>Hsp90-IN-16, a selective HSP90 inhibitor, targets HER2+ cancers with 6 μM IC50 in HCC1954 cells, blocking client proteins and inducing apoptosis.</p>Formula:C30H26FN3O6Color and Shape:SolidMolecular weight:543.54Metocurine chloride
CAS:<p>Metocurine: a muscle relaxant, not for kidney failure patients as it's kidney-excreted.</p>Formula:C40H48Cl2N2O6Color and Shape:SolidMolecular weight:723.72Vindeburnol
CAS:<p>Vindeburnol is a cerebral vasodilator vincamine analog that bears neuroprotective properties.</p>Formula:C17H20N2OColor and Shape:SolidMolecular weight:268.35Fasitibant
CAS:<p>Fasitibant is a potent and selective nonpeptide kinin B2 receptor antagonist.</p>Formula:C36H49Cl2N6O6SColor and Shape:SolidMolecular weight:764.78Plumbemycin B
CAS:<p>Plumbemycin B is isolated from Streptomyces plumbeus; an L-threonine antagonist.</p>Formula:C12H21N4O8PColor and Shape:SolidMolecular weight:380.29AChE-IN-10
<p>AChE-IN-10 (24r) inhibits AChE (IC50=2.4 nM), reducing amyloid buildup, tau phosphorylation, and promotes neuron health.</p>Formula:C23H27F2NO4SColor and Shape:SolidMolecular weight:451.53Antileishmanial agent-4
<p>Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].</p>Formula:C17H18N4O4Color and Shape:SolidMolecular weight:342.35Carbodine
CAS:<p>Carbodine is an antiviral targeting CTP synthetase, effective against influenza A0/PR-8/34 and A2/Aichi/2/68.</p>Formula:C10H15N3O4Purity:98%Color and Shape:SolidMolecular weight:241.24PF-00446687
CAS:<p>PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM).</p>Formula:C28H36F2N2O2Purity:98%Color and Shape:SolidMolecular weight:470.59eeAChE-IN-1
<p>eeAChE-IN-1 is a strong inhibitor of eeAChE (IC50: 23 nM).</p>Formula:C27H30N6O5SColor and Shape:SolidMolecular weight:550.63STING agonist-20
CAS:<p>STING agonist-20: potent, aids in XMT-2056 synthesis, used as a cancer vaccine adjuvant.</p>Formula:C36H39N11O8Color and Shape:SolidMolecular weight:753.76Tamitinol
CAS:<p>Tamitinol is a neurotropic drug. It has been found to help symptoms of obsessive rumination in conjunction with maprotiline.</p>Formula:C12H20N2OSPurity:98%Color and Shape:SolidMolecular weight:240.37hCAII-IN-3
<p>hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.</p>Formula:C17H21N3O3SColor and Shape:SolidMolecular weight:347.43FAAH/MAGL-IN-1
<p>FAAH/MAGL-IN-1 (SIH 3) inhibits FAAH & MAGL with IC50 of 31 & 29 nM, useful in neuropathic pain research.</p>Formula:C15H9Cl2N3O3Color and Shape:SolidMolecular weight:350.16L-I-OddU
CAS:<p>L-I-OddU: Selective anti-EBV, halts virus DNA/protein synthesis. EC50: 0.03 µM, low toxicity (CC50: 1000 nM).</p>Formula:C8H9IN2O5Color and Shape:SolidMolecular weight:340.07IL-17 modulator 5
CAS:<p>IL-17 modulator 5 is a IL-17 inhibitor, with an IC 50 of 1 nM .</p>Formula:C28H23F6N9O2Color and Shape:SolidMolecular weight:631.53HIV-IN-3
<p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>Formula:C21H32ClN7O3Color and Shape:SolidMolecular weight:465.98BIIE-0246 HCl
CAS:<p>BIIE-0246: A potent, non-peptide Y2 receptor antagonist; >650-fold more selective than Y1, Y4, Y5.</p>Formula:C49H59Cl2N11O6Color and Shape:SolidMolecular weight:968.97Steroid sulfatase/17β-HSD1-IN-4
<p>Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a potent dual inhibitor of steroid sulfatase ( STS ) and 17β-hydroxysteroid dehydrogenase type 1 ( 17β HSD1 ).</p>Formula:C18H17N3O4S2Color and Shape:SolidMolecular weight:403.48WDR5-IN-5
CAS:<p>WDR5-IN-5: Selective oral inhibitor for WDR5's WIN site with high affinity (Ki<0.02 nM) and anti-cancer properties. Good pharmacokinetics.</p>Formula:C29H29F3N6OColor and Shape:SolidMolecular weight:534.58Karenitecin
CAS:<p>Karenitecin (Cositecan) is an inhibitor of topoisomerase I. It has potent anti-cancer activity.</p>Formula:C25H28N2O4SiPurity:98%Color and Shape:SolidMolecular weight:448.59IACS-8779
CAS:<p>IACS-8779 is a potent STING agonist that efficiently stimulates interferon gene activity and exhibits strong systemic antitumor effects.</p>Formula:C21H25N9O10P2S2Purity:98%Color and Shape:SolidMolecular weight:689.55J-104871
CAS:<p>J-104871 (UNII-6137X5QNJF) is an FTase inhibitor that inhibits tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.</p>Formula:C38H32N2O12Purity:98%Color and Shape:SolidMolecular weight:708.67Suloctidil HCl
CAS:<p>Suloctidil HCl is a peripheral vascular dilator.</p>Formula:C20H36ClNOSColor and Shape:SolidMolecular weight:374.02FWM-1
<p>FWM-1 blocks SARS-CoV-2 NSP13, hinders ATP binding, with -328.6 kcal/mol binding energy.</p>Formula:C15H11ClN4O4S2Color and Shape:SolidMolecular weight:410.86Esorubicin
CAS:<p>Esorubicin, a doxorubicin derivative, intercalates DNA, inhibits topoisomerase II, has less cardiotoxicity, but more myelosuppression.</p>Formula:C27H29NO10Color and Shape:SolidMolecular weight:527.52Intoplicine
CAS:<p>Intoplicine is an inhibitor of DNA topoisomerase I and II.</p>Formula:C21H24N4OPurity:98%Color and Shape:SolidMolecular weight:348.44IRE1α kinase-IN-4
CAS:<p>IRE1α kinase-IN-4 (compound 6) is a potent inhibitor of IRE1α, exhibiting a Ki value of 140 nM. It acts as an ATP-competitive ligand for IRE1α [1].</p>Formula:C29H31N7O2Color and Shape:SolidMolecular weight:509.6KIRA9
<p>KIRA9 inhibits IRE1 with a 4.8 μM IC50, blocking ER-stress-induced mRNA decay and apoptosis by fully binding IRE1's ATP site.</p>Formula:C27H27F3N6O3SColor and Shape:SolidMolecular weight:572.6PLAP-IN-1
CAS:<p>PLAP-IN-1: Potent, selective inhibitor of PLAP, IC50 of 32 nM; doesn't notably inhibit TNAP.</p>Formula:C25H21Cl2N3O5Color and Shape:SoildMolecular weight:514.36LY 215890
CAS:<p>LY 215890 is a compound that exhibits potent Gram-negative and Gram-positive antibacterial activity.</p>Formula:C13H12ClN5O5SPurity:98%Color and Shape:SolidMolecular weight:385.78USP7-IN-10
CAS:<p>USP7-IN-10 is a potent inhibitor of ubiquitin-specific protease 7 (USP7), exhibiting an inhibition concentration half-maximal (IC50) value of 13.39 nM.</p>Formula:C26H29ClN4O3SColor and Shape:SolidMolecular weight:513.05MLKL-IN-6
<p>MLKL-IN-6 (compound P28) is a mixed lineage kinase inhibitor that specifically targets the Mixed Lineage Kinase domain-like (MLKL) protein.</p>Formula:C20H18N4O5Purity:98%Color and Shape:SolidMolecular weight:394.38AVE-1330A sodium
CAS:<p>AVE-1330A sodium is a beta-Lactamase inhibitor.</p>Formula:C7H10N3NaO6SColor and Shape:SolidMolecular weight:287.23FPR2 agonist 2
<p>Potent FPR2 agonist, crosses blood-brain barrier, EC50: 0.13 nM; reduces inflammation and mitochondrial dysfunction, inhibits caspase-3.</p>Formula:C25H20F2N4O2Color and Shape:SolidMolecular weight:446.45HIV-1 inhibitor-40
<p>HIV-1 inhibitor-40 (4ab) is a potent NNRTI (EC50: 1.9 nM), non-toxic in vivo, and a sensitive CYP inhibitor.</p>Formula:C25H18N6O2Color and Shape:SolidMolecular weight:434.45(+)-Cevimeline hydrochloride hemihydrate
<p>(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.</p>Formula:C10H19ClNO1·5SPurity:98%Color and Shape:SolidMolecular weight:244.78Mesulergine hydrochloride
CAS:<p>5-HT2A and 2C receptor antagonist</p>Formula:C18H27ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:398.95Netupitant metabolite Monohydroxy Netupitant
CAS:<p>Monohydroxy Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite.</p>Formula:C30H32F6N4O2Purity:98%Color and Shape:SolidMolecular weight:594.59Glycyl H-1152 hydrochloride
CAS:<p>Glycyl-H-1152 is a potent ROCK-II inhibitor (IC50=11.8 nM) with high selectivity over CaMKII, PKG, Aurora A, PKA, and PKC. Better than Y-27632 and HA-1077.</p>Formula:C18H26Cl2N4O3SColor and Shape:SolidMolecular weight:449.39Antitumor agent-75
<p>Antitumor agent-75 is a novel and potent antitumor agent.</p>Formula:C26H23FN6Color and Shape:SolidMolecular weight:438.5Carbacyclin
CAS:<p>Carbacyclin, a PGI2 analog, is a prostacyclin (PGI2) receptor agonist and vasodilator with potent inhibitory platelet aggregation.</p>Formula:C21H34O4Purity:98%Color and Shape:SolidMolecular weight:350.49(S)-Purvalanol B
CAS:<p>(S)-Purvalanol B is the S enantiomer of Purvalanol B. Purvalanol B is an inhibitor of cyclin-dependent kinase(CDK) .</p>Formula:C20H25ClN6O3Purity:98%Color and Shape:SolidMolecular weight:432.9HOE-288
CAS:<p>HOE-288 is a converting enzyme (CE) inhibitor.</p>Formula:C27H38N2O5Color and Shape:SolidMolecular weight:470.60Hesperadin hydrochloride
<p>Hesperadin hydrochloride is an ATP-competitive indolone inhibitor of Aurora A and B, with an IC50 value of 250 nM for Aurora B.</p>Formula:C29H33ClN4O3SColor and Shape:SolidMolecular weight:553.12EGFR-IN-45
<p>EGFR-IN-45: Strong EGFR/CDK2 inhibitor (IC50s: 0.4 & 1.6 μM), halts cancer cell cycle pre-G1, prompts apoptosis, also targets Topo I/II.</p>Formula:C28H23N7OColor and Shape:SolidMolecular weight:473.53[D-Leu-4]-OB3
CAS:[D-Leu-4]-OB3 suppresses the expression of genes associated with inflammation, proliferation, and metastasis, as well as the expression of PD-L1.Formula:C29H50N8O12SColor and Shape:SolidMolecular weight:734.82NTPDase-IN-3
CAS:<p>NTPDase-IN-3 inhibits NTPDase1/2/3/8 (IC50: 0.21/1.07/0.38/0.05 μM), useful for cancer and thrombosis research.</p>Formula:C22H24ClN3OS2Color and Shape:SolidMolecular weight:446.03NDM-1 inhibitor-3
<p>NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.</p>Formula:C16H12O4Purity:98.66%Color and Shape:SolidMolecular weight:268.26KRAS G12D inhibitor 11
CAS:<p>KRAS G12D inhibitor 11 targets KRAS G12D in cancer research (patent WO2021108683A1, compound 52).</p>Formula:C29H38BN5O3Color and Shape:SolidMolecular weight:515.45Befiradol hydrochloride
CAS:<p>Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.</p>Formula:C20H23Cl2F2N3OPurity:99.1%Color and Shape:SolidMolecular weight:430.32MRS2279 diammonium
CAS:<p>MRS2279 diammonium, a P2Y1 antagonist with K i 2.5 nM, IC 50 51.6 nM, blocks ADP-induced platelet aggregation, pK b 8.05.</p>Formula:C13H24ClN7O8P2Color and Shape:SolidMolecular weight:503.77Keap1-Nrf2-IN-4
<p>Keap1-Nrf2-IN-4 hinders MGC-803 cell growth (IC50=2.55μM), migration, and induces apoptosis with low toxicity.</p>Formula:C26H34N2OColor and Shape:SolidMolecular weight:390.56Spicamycin
CAS:<p>Spicamycin can be used as a potent inducer of differentiation of human myeloid leukemia cells (HL-60) and murine myeloid leukemia cells (M1).</p>Formula:C30H51N7O7Color and Shape:SolidMolecular weight:621.77CDK/HDAC-IN-1
<p>CDK/HDAC-IN-1 inhibits CDK2/4/6 & HDAC6 with IC50s: 60.9, 276, 27.2, and 128.6 nM respectively.</p>Formula:C20H18N4O4Color and Shape:SolidMolecular weight:378.38Anticancer agent 65
CAS:<p>Anticancer agent 65: Effective on A549 cells, IC50 1.07 μM, halts S phase, triggers apoptosis, elevates p53/p21, causes ROS and MMP collapse.</p>Formula:C36H63NO5Color and Shape:SolidMolecular weight:589.89Brostallicin HCl
CAS:<p>Brostallicin, a synthetic MGB, inhibits DNA replication in cancer cells, inducing cell death, effective against MMR-defective tumors.</p>Formula:C30H36BrClN12O5Color and Shape:SolidMolecular weight:760.04Anti-inflammatory agent 6
<p>Anti-inflammatory agent 6 blocks IKKα/β, IκBα, and NF-κB p65 phosphorylation, key to controlling inflammation.</p>Formula:C22H20O12Color and Shape:SolidMolecular weight:476.39AZD 4407
CAS:<p>AZD 4407 is a potent inhibitor of 5-lipoxygenase.</p>Formula:C19H21NO3S2Purity:98%Color and Shape:SolidMolecular weight:375.5HDAC-IN-33
<p>HDAC-IN-33 inhibits HDAC1/2/6 (IC50: 24/46/47 nM), exhibits potent antitumor activity in vitro and in vivo, and activates antitumor immunity.</p>Formula:C21H25N3O3Color and Shape:SolidMolecular weight:367.44K-14585
CAS:<p>K-14585 blocks PAR(2), reduces NFkappaB activity, and IL-8 response, but alone can boost IL-8.</p>Formula:C51H56Cl2N8O4Color and Shape:SolidMolecular weight:915.95PPARγ phosphorylation inhibitor 1
<p>PPARγ phosphorylation inhibitor 1 (Compound 10) is a potent PPARγ binding agent (IC50: 24 nM) with antidiabetic effects.</p>Formula:C22H14Cl2N2O4Color and Shape:SolidMolecular weight:441.26Sulprostone
CAS:<p>EP3 and EP1 receptor agonist</p>Formula:C23H31NO7SPurity:98%Color and Shape:White To Off-White SolidMolecular weight:465.56DNA crosslinker 2 dihydrochloride
CAS:<p>Potent DNA crosslinker 2 binds minor groove, increases Tm by 1.2°C, and inhibits NCI-H460, A2780, MCF-7 cancer cells.</p>Formula:C15H22Cl2N8OColor and Shape:SolidMolecular weight:401.29FGFR4-IN-10
<p>FGFR4-IN-10 (compound 5a) is a potent, selective FGFR4 inhibitor with IC50 of 70.7 nM, sparing FGFR1-3.</p>Formula:C20H19F3N6O3Color and Shape:SolidMolecular weight:448.4DNA-PK-IN-6
CAS:<p>DNA-PK-IN-6 inhibits DNA-PKcs, disrupting tumor DNA repair and triggering apoptosis; enhances radiotherapy and targets various tumors (WO2021197159A1).</p>Formula:C19H21N7OColor and Shape:SolidMolecular weight:363.42Anti-inflammatory agent 16
<p>Compound 14 is a peptidomimetic that significantly lowers TNFα, NO, CD40, and CD86, showcasing strong anti-inflammatory effects.</p>Formula:C21H23N5O3Color and Shape:SolidMolecular weight:393.44MsbA-IN-2
<p>MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).</p>Formula:C23H19Cl2NO3Color and Shape:SolidMolecular weight:428.31HIV-1 inhibitor-8
<p>HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.</p>Formula:C25H21N5OSColor and Shape:SolidMolecular weight:439.53Terguride
CAS:<p>Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.</p>Formula:C20H28N4OColor and Shape:SolidMolecular weight:340.46Anticancer agent 143
CAS:<p>Anticancer Agent 143 (Compound 369), a potent dual inhibitor targeting PTPN2 and PTP1B, exhibits IC50 values below 2.5 nM.</p>Formula:C19H15BrF2N3O6PS2Purity:98%Color and Shape:SolidMolecular weight:594.34HIV-1 inhibitor-17
<p>HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).</p>Formula:C32H32N4O5SColor and Shape:SolidMolecular weight:584.69JTE 151A
CAS:<p>JTE-151 is a novel RORγ inverse agonist.</p>Formula:C26H30ClN3O5Color and Shape:SolidMolecular weight:499.99LSD1-IN-21
<p>LSD1-IN-21: potent LSD1 inhibitor, crosses blood-brain barrier, IC50 of 0.956 μM; lowers TNF-α, anti-cancer, anti-inflammatory.</p>Formula:C24H25N5O2SColor and Shape:SolidMolecular weight:447.55Dictyostatin
CAS:<p>Dictyostatin: potent microtubule stabilizer & anticancer agent with antiproliferative effects; researched for tauopathies.</p>Formula:C32H52O6Color and Shape:SolidMolecular weight:532.75Antibacterial agent 110
<p>Compound 4e, an antibacterial against P. aeruginosa, disrupts cell membranes (MIC: 1 μg/ml).</p>Formula:C22H21N5O4SColor and Shape:SolidMolecular weight:451.5Carbonic anhydrase inhibitor 2
CAS:<p>Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.</p>Formula:C12H16N4O6SColor and Shape:SolidMolecular weight:344.34PAD2-IN-1 hydrochloride
<p>PAD2-IN-1 hydrochloride: potent, selective PAD2 inhibitor; 95x less on PAD4, 79x less on PAD3; benzimidazole derivative.</p>Formula:C25H30ClFN6O3Color and Shape:SolidMolecular weight:517Dup-714
CAS:<p>Dup-714 is a thrombin inhibitor.</p>Formula:C21H33BN6O5Purity:98%Color and Shape:SolidMolecular weight:460.33LasR-IN-3
<p>LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.</p>Formula:C22H19N3O2Color and Shape:SolidMolecular weight:357.41(-)-Cevimeline hydrochloride hemihydrate
<p>(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.</p>Formula:C10H19ClNO1·5SPurity:98%Color and Shape:SolidMolecular weight:244.78G108
CAS:<p>G108 is an inhibitor of human cGAS and is used in the study of autoimmune diseases associated with human cGAS.</p>Formula:C16H14Cl2N4O2Purity:99.13% - 99.75%Color and Shape:SolidMolecular weight:365.21AZ-PFKFB3-67 quarterhydrate
<p>AZ-PFKFB3-67 quarterhydrate inhibits PFKFB3 (IC50: 11 nM), PFKFB2 (159 nM), and PFKFB1 (1130 nM).</p>Formula:C26H27N5O4Color and Shape:SolidMolecular weight:460.01VEGFR-2-IN-12
<p>VEGFR-2-IN-12 (compound 6g), a 2-oxoquinoxalinyl-1,2,4-triazole, is a potent inhibitor of VEGFR-2 (IC50: 0.037 μM). VEGFR-2-IN-12 has anti-tumour effects.</p>Formula:C22H24N6O3SColor and Shape:SolidMolecular weight:452.53HDAC2-IN-1
<p>HDAC2-IN-1 is an oral HDAC2 inhibitor (IC50: 0.5 μM), crosses the blood-brain barrier, and inhibits HDAC1 and HDAC8.</p>Formula:C22H23ClN4OSColor and Shape:SolidMolecular weight:426.96Cacospongionolide B
CAS:<p>Cacospongionolide B from Fasciospongia cavernosa inhibits secretory phospholipase A2, curbing inflammation.</p>Formula:C25H36O4Color and Shape:SolidMolecular weight:400.55JAK3-IN-13
<p>JAK3-IN-13: Oral JAK3 inhibitor, selective & potent. Acts on NK1, JNK2, JNK3, Tyk2. Anti-tumor. IC50: JNK3, 8 nM; Tyk2, 365 nM; JNK2, 2039 nM; NK1, 4728 nM.</p>Formula:C25H33ClN6O5Color and Shape:SolidMolecular weight:533.02Quinagolide hydrochloride
CAS:<p>Quinagolide hydrochloride is a selective agonist of dopamine D2 receptor.</p>Formula:C20H34ClN3O3SPurity:98%Color and Shape:SolidMolecular weight:432.02CHF-6366
CAS:<p>CHF-6366: M3 antagonist & β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.</p>Formula:C42H48N6O8Color and Shape:SolidMolecular weight:764.87CB2 receptor antagonist 1
CAS:<p>Compound 29 is a potent, CB2-selective antagonist/reverse agonist. Derivatives 23 & 24 offer antinociception; 24 activates cannabinoid/TRPV1 receptors.</p>Formula:C28H47NO3Color and Shape:SolidMolecular weight:445.68NB-533
CAS:<p>NB-533 is a macrocyclic peptidic BACE-1 inhibitor.</p>Formula:C33H55N3O4Color and Shape:SolidMolecular weight:557.81Trypanothione synthetase-IN-4
<p>Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).</p>Formula:C29H52INO2Color and Shape:SolidMolecular weight:573.63Tovinontrine
CAS:<p>Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment.</p>Formula:C21H26N6O2Purity:98.14%Color and Shape:SolidMolecular weight:394.47PDE4-IN-5
<p>PDE4-IN-5: potent PDE4 inhibitor, IC50 = 3.1 nM, superb skin penetration, anti-psoriasis effect.</p>Formula:C21H28N2O3Color and Shape:SolidMolecular weight:356.46PPI-2458
CAS:<p>PPI-2458, a fumagillin derivative, irreversibly blocks MetAP2, hindering abnormal cell growth and angiogenesis with improved toxicity.</p>Formula:C22H36N2O6Color and Shape:SolidMolecular weight:424.53Latrunculin M
CAS:<p>Latrunculin M, a novel marine toxin, disrupts microfilament organization in cultured cells.</p>Formula:C21H33NO5SColor and Shape:SolidMolecular weight:411.55MEK4 inhibitor-2
CAS:<p>MEK4 Inhibitor-2, a novel MEK4 inhibitor, demonstrates efficacy against pancreatic adenocarcinoma, exhibiting an IC50 value of 83 nM.</p>Formula:C20H15FN4O3SColor and Shape:SolidMolecular weight:410.42Saprisartan potassium
CAS:<p>Saprisartan potassium is an Angiotensin II Type 1 receptor antagonist and antihypertensive agent.</p>Formula:C25H21BrF3KN4O4SColor and Shape:SolidMolecular weight:649.52CEP-2563
CAS:<p>CEP-2563 is a prodrug of CEP-751. It also used as an antitumor agent, inhibiting protein kinases.</p>Formula:C36H41ClN6O6Purity:98%Color and Shape:SolidMolecular weight:689.20BU09059
CAS:<p>BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).</p>Formula:C28H37N3O5Purity:98%Color and Shape:SolidMolecular weight:495.61M1069
<p>M1069 is an oral A2A/A2B receptor antagonist, 100x more selective over A1/A3, with antitumor properties by blocking adenosine's immunosuppressive effects.</p>Formula:C25H30N4O8SColor and Shape:SolidMolecular weight:546.59CYP11B1-IN-2
<p>CYP11B1-IN-2 selectively inhibits human and rat CYP11B1 (IC50: 9/25 nM) orally to research cortisol-related diseases.</p>Color and Shape:SolidFostriecin (free base)
CAS:<p>Fostriecin inhibits PP2A/PP4 (IC50s = 3.2/3 nM), weakly affects topoisomerase II/PP1 (IC50s = 40/131 μM), doesn't inhibit PP2B, and may modify epigenetics.</p>Formula:C19H27O9PColor and Shape:SolidMolecular weight:430.39AM679
CAS:<p>AM679: potent, selective FLAP inhibitor; IC50s—2.2 nM (FLAP), 0.6 nM (hLA), 154 nM (hWB); blocks leukotrienes in vivo; no significant CYP3A4 interaction.</p>Formula:C40H44N4O5SPurity:98%Color and Shape:SolidMolecular weight:692.87CK2-IN-3
<p>CK2-IN-3: potent, selective CK2 inhibitor; Kd=12 nM, IC50: 1.51 μM (CK2α), 7.64 μM (CK2α'). For cancer research.</p>Formula:C22H26N4O7Color and Shape:SolidMolecular weight:458.46Symplostatin 1
CAS:<p>Symplostatin 1 is a dolastatin 10 analog from the marine cyanobacterium Symploca hydnoides.</p>Formula:C43H70N6O6SColor and Shape:SolidMolecular weight:799.12sEH inhibitor-1
<p>TCPU (sEH inhibitor-1) is a potent oral human sEH blocker with IC50s of 0.4 nM (human) and 5.3 nM (mouse).</p>Color and Shape:SolidMrgprX2 antagonist-6
<p>MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation.</p>Formula:C24H23F3N6O3Color and Shape:SolidMolecular weight:500.47Anticancer agent 64
CAS:<p>Anticancer agent 64 (5m) induces apoptosis, has IC50 2.4μM in CCRF-CEM, activates caspases, cleaves PARP, affects mitochondria.</p>Formula:C31H46N2O2SColor and Shape:SolidMolecular weight:510.77β-Secretase Inhibitor III
<p>β-Secretase Inhibitor III is a highly selective inhibitor of BACE1 with a Ki value of 0.13 nM.</p>Formula:C20H20F2N4O3SColor and Shape:SolidMolecular weight:434.46SGLT1/2-IN-1
CAS:<p>SGLT1/2-IN-1 is a dual SGLT1/SGLT2 inhibitor.</p>Formula:C25H28O8Color and Shape:SolidMolecular weight:456.48FTI-2153 TFA
<p>FTI-2153 TFA inhibits farnesyltransferase with high selectivity (IC50: 1.4 nM), over 3000x more than Rap1A processing.</p>Formula:C27H31F3N4O5SColor and Shape:SolidMolecular weight:580.62hCAII-IN-4
CAS:<p>hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.</p>Formula:C31H23NO9Color and Shape:SolidMolecular weight:553.529(S)-HEPE
CAS:<p>9(S)-HEPE is a monohydroxy fatty acid derived from EPA. The biological activity of 9(S)-HEPE has not been documented.</p>Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45PfPKG-IN-1
<p>PfPKG-IN-1, an imidazole-based inhibitor, targets the Plasmodium falciparum cyclic guanosine monophosphate-dependent protein kinase (PfPKG).</p>Formula:C24H22ClN7OSColor and Shape:SolidMolecular weight:492IRAK4-IN-11
<p>IRAK4-IN-11 (compound 6) is a potent inhibitor of IRAK4 with an IC 50 of 0.008 μM. IRAK4-IN-11 exhibits cell pIRAK4 potencies with an IC 50 of 0.19 μM [1].</p>Formula:C16H19N7OColor and Shape:SolidMolecular weight:325.37Antibacterial agent 81
CAS:<p>Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.</p>Formula:C33H28N2O8Color and Shape:SolidMolecular weight:580.58(S)-JDQ-443
CAS:<p>(S)-JDQ-443, an isomer of JDQ-443, is a selective, potent oral KRAS G12C inhibitor with antitumor properties.</p>Formula:C29H28ClN7OColor and Shape:SolidMolecular weight:526.03RGT-068A
CAS:<p>RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor .</p>Formula:C17H16ClN9O2Color and Shape:SolidMolecular weight:413.82CH-38083
CAS:<p>CH-38083 is a selective and effective alpha-2 adrenoceptors antagonist.</p>Formula:C18H24ClNO3Purity:98%Color and Shape:SolidMolecular weight:337.84Saussureamine C
CAS:<p>Saussureamine C is an inhibitor of H274Y and N294S mutants.</p>Formula:C19H26N2O5Color and Shape:SolidMolecular weight:362.42Anticancer agent 27
<p>Anticancer agent 27 is a promising candidate for the treatment of cancer and deserves further development.</p>Formula:C28H31NO6Color and Shape:SolidMolecular weight:477.55KAG-308
CAS:<p>KAG-308: selective EP4 agonist; Ki: 2.57 nM, EC50: 17 nM; suppresses colitis, promotes mucosal healing, inhibits TNF-α.</p>Formula:C24H30F2N4O3Purity:98%Color and Shape:SolidMolecular weight:460.52OSI-7904L free acid
CAS:<p>OSI-7904L is a folate-based thymidylate synthase inhibitor. It also has antimalarial and antitumor properties.</p>Formula:C27H24N4O6Purity:98%Color and Shape:SolidMolecular weight:500.5Scytonemin
CAS:<p>Scytonemin, a cyanobacterial pigment, inhibits cancer cell growth by decreasing Plk1 activity, especially effective on U266 myeloma cells.</p>Formula:C36H20N2O4Color and Shape:SolidMolecular weight:544.55HDAC/HSP90-IN-4
<p>HDAC/HSP90-IN-4 inhibits HDAC (20 IC50=194nM, 26 IC50=360nM) & HSP90α (20 IC50=153nM, 26 IC50=77nM), affects cancer cell survival and invasion.</p>Formula:C20H23N3O6Color and Shape:SolidMolecular weight:401.15869KDOAM-25 trihydrochloride (2230731-99-2 free base)
<p>KDOAM-25 trihydrochloride, a selective KDM5 inhibitor (IC50: 19-71 nM), boosts H3K4 methylation and hinders MM1S cell growth.</p>Formula:C15H28Cl3N5O2Purity:98%Color and Shape:SolidMolecular weight:416.77CHK1 inhibitor
CAS:<p>CHK1 inhibitor (GDC-0575 analog) is a CHK1 inhibitor.</p>Formula:C17H21BrN4OPurity:98%Color and Shape:SolidMolecular weight:377.28CD33 splicing modulator 1
<p>Compound 1 modulates CD33, affects microglial cells, and may aid in neurodegenerative disease research.</p>Formula:C25H25FN6OColor and Shape:SolidMolecular weight:444.5cis-RdRP-IN-5
<p>Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.</p>Formula:C23H21N3O5Color and Shape:SolidMolecular weight:419.43CXCR4 modulator-1
CAS:<p>CXCR4 modulator-1 (ZINC72372983) is potent (EC50=100nM) with uses in anti-inflammatory, anticancer, and anti-HIV research.</p>Formula:C23H27N5O2Color and Shape:SolidMolecular weight:405.49Cemdomespib
CAS:<p>Cemdomespib (KU-596) is a potent Hsp90 modulator with neuroprotective effects and can improve diabetic neuropathy.</p>Formula:C24H30FNO6Color and Shape:SolidMolecular weight:447.5PI3K-IN-37
CAS:<p>PI3K-IN-37 inhibits PI3K α/β/δ (IC50: 6/8/4 nM) and mTOR (IC50: 4 nM).</p>Formula:C25H26N6O2Color and Shape:SolidMolecular weight:442.51HIV-1 inhibitor-52
CAS:<p>HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.</p>Formula:C46H72FNO5SColor and Shape:SolidMolecular weight:770.13PF-00489791
CAS:<p>PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.</p>Formula:C20H28N8O4SPurity:99.97%Color and Shape:SolidMolecular weight:476.55Ciluprevir
CAS:<p>Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.</p>Formula:C40H50N6O8SPurity:98%Color and Shape:SolidMolecular weight:774.93
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