Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,838 products)
- Apoptosis(6,316 products)
- Cell Cycle/Checkpoint(4,881 products)
- Chromatin/Epigenetics(2,615 products)
- Cytoskeletal Signaling(1,570 products)
- DNA Damage/DNA Repair(2,868 products)
- Endocrinology/Hormones(3,753 products)
- Enzyme(3,673 products)
- GPCR/G-Protein(9,023 products)
- Immunology and Inflammation(3,903 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,258 products)
- Membrane Transporter/Ion Channel(3,159 products)
- Metabolism(10,130 products)
- Microbiology/Virology(7,618 products)
- Neuroscience(10,516 products)
- Other Inhibitors(35,844 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,431 products)
- Proteases/Proteasome(1,688 products)
- Stem Cell and Derivatives(729 products)
- Tyrosine Kinase/Adaptors(1,983 products)
- Ubiquitination(1,727 products)
Show 16 more subcategories
Found 66513 products of "Inhibitors"
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WF-210
CAS:WF-210 is an effective activator of procaspase-3 that acts by inducing apoptosis in cancer cells and reducing tumor growth.Formula:C41H38FN7O7SPurity:98%Color and Shape:SolidMolecular weight:791.85APO-6619
CAS:APO-6619 is an iron chelator inhibiting growth of multiple bacteria, potentially treating infections.Formula:C11H14N2O3Color and Shape:SolidMolecular weight:222.24Oxidized ATP trisodium salt
CAS:Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (Formula:C10H11N5Na3O13P3Purity:98%Color and Shape:SolidMolecular weight:571.11FEN1-IN-7
CAS:FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells.Formula:C16H14N2O6SPurity:98%Color and Shape:SolidMolecular weight:362.36(±)-ANAP
CAS:(±)-ANAP is the amino acid analog of prodan. It can be used as a fluorescent probes and enhance environmental sensitivity.Formula:C15H16N2O3Purity:98%Color and Shape:SolidMolecular weight:272.3TLR7 agonist 4
CAS:TLR7 agonist 4 (Compound 1.2) is a TLR7 agonist (EC50: 4.3 nM).Formula:C23H34N6O3Color and Shape:SolidMolecular weight:442.55PF-06459988
CAS:PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) mutant inhibitor.Formula:C19H22ClN7O3Purity:98%Color and Shape:SolidMolecular weight:431.88Cochliodone A
CAS:Cochliodone A, a bioactive compound isolated from the deep-sea fungus Chaetomium sp., exhibits both antibacterial and anticancer properties.Formula:C34H38O12Color and Shape:SolidMolecular weight:638.66FPL-65447 hydrochloride
CAS:FPL-65447 HCl is a D1 agonist for renal/cardiac failures and sepsis treatment.Formula:C17H22ClNO3Color and Shape:SolidMolecular weight:323.82AZ-TAK1
CAS:"AZ-Tak1 inhibits TAK1 kinase (IC50=0.009mM), reduces p38/ERK levels, and induces apoptosis in Mino, SP53, Jeko cells with increasing efficacy at 0.1-0.5mM."Formula:C25H28FN7O2Color and Shape:SolidMolecular weight:477.53Antifungal agent 24
CAS:Antifungal agent 24 (Compound 6) is an antifungal agent that inhibits Candida albicans (MIC: 0.03 μg/ml).Formula:C24H18F2N4OColor and Shape:SolidMolecular weight:416.42EGFR/CSC-IN-1
CAS:EGFR/CSC-IN-1 is a dual inhibitor targeting both the epidermal growth factor receptor (EGFR [IC50 10.52 nM]) and cancer stem cells (CSC), with potentialFormula:C54H54Cl2FN7O7S2Purity:98%Color and Shape:SolidMolecular weight:1067.08Dasiglucagon
CAS:Dasiglucagon is a stable human glucagon peptide analog that is rapid and effective in the treatment of severe hypoglycemia.Formula:C152H222N38O50Color and Shape:SolidMolecular weight:3381.62Zaldaride (free base)
CAS:Zaldaride (free base) is a calmodulin antagonist.Formula:C26H28N4O2Color and Shape:SolidMolecular weight:428.53AA 863
CAS:AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.Formula:C21H26O5Purity:98%Color and Shape:SolidMolecular weight:358.43XZ426
CAS:XZ426 is a potent integrase strand transfer inhibitor with anti- HIV activity .Formula:C22H24F2N4O4Color and Shape:SolidMolecular weight:446.45UNC5293
CAS:UNC5293: potent oral MERTK inhibitor, Ki=190 pM, IC50=0.9 nM; selective vs Axl/Tyro3/Flt3; good mouse PK; used in leukemia research.Formula:C30H42N6O2Color and Shape:SolidMolecular weight:518.69CCT-271850
CAS:CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.Formula:C24H29N7OPurity:98%Color and Shape:SolidMolecular weight:431.53N8-Acetylspermidine dihydrochloride
CAS:N8-Acetylspermidine dihydrochloride is a polyamine that regulates ischemic cardiac apoptosis and resultant cardiac dysfunction.Formula:C9H23Cl2N3OPurity:98% - 99.98%Color and Shape:SolidMolecular weight:260.2Ref: TM-T19466
1mg39.00€2mg52.00€5mg84.00€1mL*10mM (DMSO)101.00€10mg120.00€25mg200.00€50mg314.00€100mg505.00€A 79175
CAS:A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.Formula:C15H13FN2O4Purity:98%Color and Shape:SolidMolecular weight:304.27HCoV-OC43-IN-1
CAS:HCoV-OC43-IN-1 (Compound IV-16) serves as an inhibitor of the coronavirus HCoV-OC43, exhibiting antiviral efficacy with an EC50 of 90 nM.Formula:C23H22F6N4O2Purity:98%Color and Shape:SolidMolecular weight:500.44PRMT5-IN-29
CAS:PRMT5-IN-29 is a potent, orally active inhibitor of PRMT5, exhibiting an IC50 value of 1.5 μM, showing promise for use in advanced cancer research [1].Formula:C18H20Cl3N5O5Purity:98%Color and Shape:SolidMolecular weight:492.74ASP-8497
CAS:ASP8497 is a potent DPP-IV inhibitor enhancing GLP-1, used for type 2 diabetes and glucose intolerance.Formula:C18H27FN4O7SColor and Shape:SolidMolecular weight:462.49Androgen receptor degrader-3
CAS:Androgen Receptor Degrader-3 (ARD-3) is a compound that inhibits androgen receptor signaling and promotes the degradation of the receptor, with potentialFormula:C45H51ClN8O5Purity:98%Color and Shape:SolidMolecular weight:819.39ICMT-IN-4
CAS:ICMT-IN-4 (compound 28) serves as an inhibitor of ICMT, exhibiting an IC50 value of 0.27 μM [1].Formula:C22H29NO2Color and Shape:SolidMolecular weight:339.47MC-GGFG-(7ethanol-10NH2-11F-Camptothecin)
CAS:MC-GGFG-(7ethanol-10NH2-11F-Camptothecin) (compound 141) is a protease-cleavable drug-linker conjugate utilized in antibody-drug conjugates (ADCs), featuring anFormula:C46H47FN8O12Color and Shape:SolidMolecular weight:922.91L 640035
CAS:L 640035 inhibits human platelet aggregation which is induced by arachidonic acid, collagen, and the prostaglandin-endoperoxide analog of U44069.Formula:C15H12O3SPurity:98%Color and Shape:SolidMolecular weight:272.32TNFalpha-IN-S10
CAS:TNFalpha-IN-S10 is an inhibitor of TNF-α.Formula:C21H14N2O3SColor and Shape:SolidMolecular weight:374.41hDDAH-1-IN-2
CAS:hDDAH-1-IN-2 is an orally active human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) inhibitor.Formula:C8H20N4O2Purity:98%Color and Shape:SolidMolecular weight:204.27PD 125754
CAS:PD 125754 is a Renin inhibitor, which represents a group of pharmaceutical drugs used primarily to treat essential hypertension.Formula:C42H65N5O7Purity:98%Color and Shape:SolidMolecular weight:751.99Melafolone
CAS:Melafolone: natural COX-2/EGFR inhibitor, enhances PD-1 therapy by normalizing tumor vessels, lowers PD-L1.Formula:C22H24O7Color and Shape:SolidMolecular weight:400.42SOMCL-863
CAS:SOMCL-863 is a selective and orally bioavailable c-Met inhibitor. It shows antitumor activity both in vitro and in vivo.
Formula:C23H24F3N5O3Purity:98%Color and Shape:SolidMolecular weight:475.46HIV-IN-8
CAS:HIV-IN-8 (Compound 9) acts as an HIV inhibitor, suppressing HIV replication with an effective concentration (EC50) of 13 μg/mL [1].Formula:C36H30O16Color and Shape:SolidMolecular weight:718.61AMG-548 dihydrochloride (864249-60-5 free base)
AMG-548 dihydrochloride: oral p38α inhibitor, Ki: 0.5 nM; less so for p38β, Ki: 36 nM; >> p38γ/δ; blocks LPS-induced TNFα, IC50: 3 nM.Formula:C29H29Cl2N5OPurity:98%Color and Shape:SolidMolecular weight:534.48HDAC-IN-60
CAS:HDAC-IN-60 (compound 21a), a potent histone deacetylase (HDAC) inhibitor, promotes intracellular reactive oxygen species (ROS) production, induces DNA damage,Formula:C20H26N2O6Purity:98%Color and Shape:SolidMolecular weight:390.43Koshidacin B
CAS:Koshidacin B, a cyclic tetrapeptide, inhibits malaria strains FCR3/K1 (IC50: 0.89/0.83 μM), showing promise for antiplasmodial research.Formula:C28H40N4O7Color and Shape:SolidMolecular weight:544.64N,N-Dimethyldoxorubicin
CAS:N,N-Dimethyldoxorubicin, a Doxorubicin analogue, exhibits cytotoxicity against a range of tumor cell lines with IC50 values below 0.3 μM [1].Formula:C29H33NO11Color and Shape:SolidMolecular weight:571.57P2X3 antagonist 34
CAS:Potent P2X3 antagonist 34, oral, selective for human, rat, guinea pig receptors; IC50s: 25/92/126 nM; strong anti-tussive, no taste change.Formula:C24H26F2N4O3Purity:98%Color and Shape:SolidMolecular weight:456.48VER-00158411
CAS:VER-00158411 is a checkpoint kinase 1 and CHK2 inhibitor (IC50: 4.4 nM and 4.5 nM, respectively).Formula:C31H34N6O3Purity:98%Color and Shape:SolidMolecular weight:538.64Z1078601926
CAS:Z1078601926 is an allosteric inhibitor of the human dopamine transporter (hDAT) and exhibits a synergistic effect when combined with Nomifensine [1].Formula:C14H19FN2OColor and Shape:SolidMolecular weight:250.31GS-6201
CAS:GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor.Formula:C21H21F3N6O2Purity:99.78% - 99.94%Color and Shape:SolidMolecular weight:446.43Ref: TM-T15418
1mg34.00€5mg71.00€1mL*10mM (DMSO)78.00€10mg114.00€25mg235.00€50mg380.00€100mg572.00€200mg805.00€HDAC-IN-50
CAS:HDAC-IN-50, a potent FGFR/HDAC inhibitor (IC50: 0.18-13 nM), induces apoptosis, cell cycle arrest, and shows anti-tumor activity.Formula:C31H41N7O4Color and Shape:SolidMolecular weight:575.7BACE-1 inhibitor 1
CAS:BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).Formula:C17H14BrF3N4O2Purity:98%Color and Shape:SolidMolecular weight:443.22CXCR4 antagonist 7
CAS:Compound PARA-B, a CXCR4 antagonist with IC50 = 9.3 nM, targets HIV, cancer, inflammatory diseases, and WHIM syndrome.Formula:C15H17N5O3Color and Shape:SolidMolecular weight:315.33MK-287
CAS:MK-287 is a PAF antagonist blocking [3H]C18-PAF binding to platelets, PMNs, and lungs; may treat asthma.Formula:C25H34O9SColor and Shape:SolidMolecular weight:510.6Duocarmycin MB
CAS:Duocarmycin MB, an ADC toxin and DNA alkylating agent, combats multi-drug resistant cells.Formula:C27H26ClN3O4Purity:98%Color and Shape:SolidMolecular weight:491.972-Methoxyestrone
CAS:2-Methoxyestrone is a methoxylated catechol estrogen and the principal metabolite of 2-hydroxyestrone, a nonuterotropic metabolite of estradiol.Formula:C19H24O3Purity:97.07% - 99.18%Color and Shape:SolidMolecular weight:300.39Ref: TM-T13481
1mg47.00€5mg92.00€1mL*10mM (DMSO)101.00€10mg152.00€25mg268.00€50mg395.00€100mg583.00€200mg833.00€Alatrofloxacin
CAS:Alatrofloxacin is a prodrug of trovafloxacin.Formula:C26H25F3N6O5Color and Shape:SolidMolecular weight:558.51SOS1-IN-14
CAS:SOS1-IN-14 是选择性的、有效的、口服具有活力的 SOS1 抑制剂 (IC50: 3.9 nM)。SOS1-IN-14 能够利用 P-糖蛋白介导的外排机制在肠道内被吸收。SOS1-IN-14 能够用于 KRAS 突变的癌症的研究，且抑瘤效果比 BI-3406 好。Formula:C29H29F3N6O2Color and Shape:SolidMolecular weight:550.57Alclofenac
CAS:Alclofenac (W-7320) aids chronic rheumatism by affecting acute phase proteins and L-tryptophan binding.Formula:C11H11ClO3Purity:99.89%Color and Shape:SolidMolecular weight:226.66
