Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,849 products)
- Apoptosis(6,366 products)
- Cell Cycle/Checkpoint(4,907 products)
- Chromatin/Epigenetics(2,622 products)
- Cytoskeletal Signaling(1,585 products)
- DNA Damage/DNA Repair(2,873 products)
- Endocrinology/Hormones(3,758 products)
- Enzyme(3,673 products)
- GPCR/G-Protein(9,049 products)
- Immunology and Inflammation(3,943 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(417 products)
- MAPK Signaling(1,259 products)
- Membrane Transporter/Ion Channel(3,164 products)
- Metabolism(10,149 products)
- Microbiology/Virology(7,673 products)
- Neuroscience(10,547 products)
- Other Inhibitors(35,859 products)
- Oxidation-Reduction(41 products)
- PI3K/Akt/mTOR Signaling(1,435 products)
- Proteases/Proteasome(1,692 products)
- Stem Cell and Derivatives(734 products)
- Tyrosine Kinase/Adaptors(1,991 products)
- Ubiquitination(1,743 products)
Show 16 more subcategories
Found 66517 products of "Inhibitors"
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NLRP3-IN-18
CAS:NLRP3-IN-18, also known as compound 13, is a potent inhibitor of NLRP3, demonstrating an IC50 value of ≤1.0 µM [1].Formula:C19H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:339.82APS3
CAS:APS3 is an inhibitor of GABA and nACh receptors, exhibiting an LC50 value of 7.2423 μg/mL against Plutella xylostella [1].Formula:C18H7Cl2F6N5O5S2Color and Shape:SolidMolecular weight:622.31Agerafenib hydrochloride
CAS:Agerafenib hydrochloride is a highly potent inhibitor of BRAFV600E (Kd: 14 nM).Formula:C24H23ClF3N5O5Purity:98%Color and Shape:SolidMolecular weight:553.92BMS-186511
CAS:BMS-186511: An FT inhibitor targeting malignant cells in NF1, halting growth and spread without affecting related enzymes.Formula:C34H60N3O7PSColor and Shape:SolidMolecular weight:685.89NaPi2b Inhibitor 15
CAS:NaPi2b, key in phosphate balance, is in intestines, lungs, testes. Blocking it may treat hyperphosphatemia by lowering serum phosphate.Formula:C44H58ClF3N4O11SColor and Shape:SolidMolecular weight:943.46AMPK-IN-1
CAS:AMPK-IN-1 is an activator of the AMP-activated protein kinase (AMPK) enzyme, specifically targeting the α2β2γ1 isoform with an EC50 of 551 nM.Formula:C24H18ClN3O3Color and Shape:SolidMolecular weight:431.87DNA gyrase B-IN-3
CAS:DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, acts as an inhibitor of bacterial DNA gyrase B and exhibits antibacterial activity against GramFormula:C14H9Cl2N3O4SPurity:98%Color and Shape:SolidMolecular weight:386.21Loflucarban
CAS:Loflucarban (Fluonilid) is an antimycotic compoud.Formula:C13H9Cl2FN2SPurity:98.08% - 98.15%Color and Shape:SolidMolecular weight:315.19VT-1598
CAS:VT-1598 is a novel, selective, orally active fungal CYP51 inhibitor. VT-1598 exhibits antifungal effects against Candida albicans.Formula:C31H20F4N6O2Color and Shape:SolidMolecular weight:584.52Propiolactone
CAS:Propiolactone (β-propiolactone; 2-Oxetanone), a chemosterilant, effectively inactivates viruses, rendering them non-infectious.Formula:C3H4O2Purity:98%Color and Shape:SolidMolecular weight:72.06Cmpd-A
CAS:Cmpd-A: Time-dependent CENP-E inhibitor, ATPase-blocking, induces mitotic arrest, halts cancer cell proliferation.Formula:C30H27F4N5O4SColor and Shape:SolidMolecular weight:629.63IM-491
CAS:IM-491 is a TNF-alpha converting enzyme inhibitor.Formula:C25H28N4O4Color and Shape:SolidMolecular weight:448.51CAXII-IN-1
CAS:CAXII-IN-1, antitumor, selectively inhibits CA XII with Ki of 3.8 nM for hCA XII and 56 nM for hCA IX.Formula:C13H7Cl2NO3SColor and Shape:SolidMolecular weight:328.17AAPK-25
CAS:AAPK-25, a dual Aurora/PLK inhibitor, disrupts mitosis, induces apoptosis, and has antitumor properties.Formula:C21H13Cl2N3O2SPurity:97.05%Color and Shape:SolidMolecular weight:442.32Ref: TM-T10215
1mg54.00€5mg118.00€1mL*10mM (DMSO)131.00€10mg172.00€25mg313.00€50mg469.00€100mg680.00€CI-959 free acid
CAS:CI-959 Free Acid is an orally effective inhibitor of cell activation in vitro and in animal models and also has anti-allergic/anti-inflammatory properties.Formula:C14H15N5O3SColor and Shape:SolidMolecular weight:333.37Chinese gallotannin
CAS:Chinese gallotannin, a non-specific promiscuous inhibitor of α-amylase, exhibits a K(i) value of 0.82 μg/mL against human salivary α-amylase and shows potentialFormula:C76H52O46Purity:98%Color and Shape:SolidMolecular weight:1701.2Ras inhibitor 134
CAS:Ras inhibitor 134 can be used in studies about Ras.Formula:C23H21ClFN5O3Color and Shape:SoildMolecular weight:469.9AalphaC
CAS:AalphaC (2-Amino-alpha-carboline) is a potential carcinogen.Formula:C11H9N3Purity:99.32%Color and Shape:Crystalline SolidMolecular weight:183.21Anti-inflammatory agent 63
CAS:Anti-inflammatory agent 63 exhibits potent inhibitory activity (EC50 = 5.33±0.57 μM) against lipopolysaccharide (LPS)-induced nitric oxide (NO) production inFormula:C18H15NO4Color and Shape:SolidMolecular weight:309.32Cyclopentenyl uracil
CAS:Cyclopentenyl uracil 是一种无细胞毒性的尿苷激酶 (uridine kinase) 抑制剂，可有效阻断完整小鼠体内宿主和肿瘤组织对循环尿苷的回收。Formula:C10H12N2O5Color and Shape:SolidMolecular weight:240.21XR9051
CAS:XR9051, a synthetic derivative of a natural compound, potently reverses P-glycoprotein MDR (EC50 = 1.4 nM) by inhibiting cytotoxic binding.Formula:C39H38N4O5Color and Shape:SolidMolecular weight:642.74CBP-IN-1
CAS:CBP-IN-1 (compound 12) acts as a potent CBP inhibitor exhibiting an IC50 of 1.5 nM and additionally suppresses CBP BRET and BRD4(1) with IC50 values of 690 nMFormula:C27H33F2N7OPurity:98%Color and Shape:SolidMolecular weight:509.5915(S)-HEDE
CAS:15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 μM.Formula:C20H36O3Color and Shape:SolidMolecular weight:324.5Atiprimod (free base)
CAS:Atiprimod: an oral azaspirane inhibiting STAT3, blocking IL-6/VEGF pathways, and promoting apoptosis by downregulating Bcl-2 and Mcl-1.Formula:C22H44N2Color and Shape:SolidMolecular weight:336.6BMX-IN-1
CAS:BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosineFormula:C29H24N4O4SPurity:98.38%Color and Shape:SolidMolecular weight:524.59mAChR antagonist 1
CAS:Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,Formula:C19H22N2O2Color and Shape:SolidMolecular weight:310.39HPK1-IN-33
CAS:HPK1-IN-33 inhibits HPK1 with 1.7 nM potency, reduces IL-2 in Jurkat cells with 286 nM EC50, and is less effective in HPK1 KO cells.Formula:C18H16ClFN6Color and Shape:SolidMolecular weight:370.81ICMT-IN-47
CAS:ICMT-IN-47 (compound 26) acts as an ICMT inhibitor with an IC50 value of 0.76 μM [1].Formula:C25H35NOColor and Shape:SolidMolecular weight:365.55APE1-IN-2
CAS:APE1-IN-2 (AP1), a Pt(IV) proagent, targets APE1 protein, induces DNA damage, and triggers apoptosis with anticancer effects.Formula:C9H12Cl2N4O5PtPurity:98%Color and Shape:SolidMolecular weight:522.21Dov-Val-Dil-OH TFA
CAS:Dov-Val-Dil-OH: a key intermediate for producing MMAE and other auristatins, inhibits cell division by blocking tubulin polymerization.Formula:C24H44F3N3O7Color and Shape:SolidMolecular weight:543.6252Imexon
CAS:Imexon is an iminopyrrolidone aziridine. It has anti-cancer activity.Formula:C4H5N3OPurity:98%Color and Shape:SolidMolecular weight:111.1cis-ent-Tadalafil
CAS:cis-ent-Tadalafil (cis-ent-IC-351) is a potent and selective PDE5 inhibitor that lowers blood pressure.Formula:C22H19N3O4Purity:99.86%Color and Shape:SolidMolecular weight:389.4LM-030
CAS:LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).Formula:C46H72N8O12Color and Shape:SolidMolecular weight:929.11Tomicorat
CAS:Tomicorat is an anti-inflammatory agent.Formula:C32H30FNO5Color and Shape:SolidMolecular weight:527.58Arzoxifene hydrochloride
CAS:Arzoxifene hydrochloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue.Formula:C28H30ClNO4SPurity:98%Color and Shape:SolidMolecular weight:512.06MRK-560
CAS:MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.Formula:C19H17ClF5NO4S2Purity:98.87%Color and Shape:SolidMolecular weight:517.92Carmoxirole hydrochloride
CAS:Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.Formula:C24H27ClN2O2Purity:99.37% - 99.62%Color and Shape:SolidMolecular weight:410.94Ref: TM-T10683
1mg42.00€5mg86.00€1mL*10mM (DMSO)88.00€10mg123.00€25mg203.00€50mg299.00€100mg411.00€200mg553.00€Epimetendiol
CAS:Epimetendiol is an anabolic agentFormula:C20H32O2Color and Shape:SolidMolecular weight:304.472-Ethynyl Adenosine
CAS:2-Ethynyl Adenosine, Adenosine derivative, tracks novel polyadenylated transcription, non-radioactive AMPylation reporter.Formula:C12H13N5O4Color and Shape:SolidMolecular weight:291.26Z-DEVD-CMK
CAS:Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].Formula:C27H35ClN4O12Color and Shape:SolidMolecular weight:643.04mGAT3/4-IN-2
CAS:mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.Formula:C26H32ClN3OS2Color and Shape:SolidMolecular weight:502.13Fosalvudine tidoxil
CAS:Fosalvudine tidoxil, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C35H64FN2O8PSPurity:98%Color and Shape:SolidMolecular weight:722.93ERK-IN-2 free base
CAS:ERK-IN-2 free base inhibits ERK2 (IC50: 1.8 nM); potential off-target effects at >10 μM.Formula:C16H17N5O2Color and Shape:SolidMolecular weight:311.34Cgp 20309
CAS:CGP 20309 is a kind of thiocarbonylamide with high anti filamentous activity.Formula:C18H26N4OS2Color and Shape:SolidMolecular weight:378.55(1R)-Deruxtecan
CAS:Deruxtecan (1R) is a drug-linker conjugate for antibody-drug conjugates (ADC) [1].Formula:C52H56FN9O13Color and Shape:SolidMolecular weight:1034.05CT1113
CAS:CT1113, a potent inhibitor of both USP28 and USP25, effectively reduces MYC levels in vivo and demonstrates anti-tumor efficacy in a mouse pancreatic cancer CDXFormula:C25H29N5O2SColor and Shape:SolidMolecular weight:463.65-Azacytidine 5′-triphosphate
CAS:5-Azacytidine 5′-triphosphate (5-aza-CMP), a cytidine analog, selectively inhibits the incorporation of [^3H]CTP into RNA during the DNA-dependent RNAFormula:C8H15N4O14P3Color and Shape:SolidMolecular weight:484.14Difamilast
CAS:Difamilast is a selective inhibitor of phosphodiesterase-4 (PDE4) with particularly efficient inhibition of subtype B (IC50=11.2 nM).Formula:C23H24F2N2O5Purity:99.47% - 99.64%Color and Shape:SolidMolecular weight:446.44AGN194204
CAS:AGN194204 (IRX4204), an oral RXR agonist, inactive against RAR, has Kd 0.4-3.8 nM & EC50 0.08-0.8 nM, with anti-inflammatory and anticarcinogenic properties.Formula:C24H32O2Purity:98%Color and Shape:SolidMolecular weight:352.51L-742001 Hydrochloride
CAS:L-742001 Hydrochloride is an RNA polymerase inhibitor.Formula:C23H25Cl2NO4Color and Shape:SolidMolecular weight:450.36
