Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,834 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,613 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,015 products)
- Immunology and Inflammation(3,904 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,257 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,137 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,423 products)
- Other Inhibitors(35,848 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,429 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(732 products)
- Tyrosine Kinase/Adaptors(1,982 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66516 products of "Inhibitors"
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Tubulosine
CAS:Tubulosine is an anticancer agent that inhibits cancer cell growth.Formula:C29H37N3O3Color and Shape:SolidMolecular weight:475.62MK-7128
CAS:MK-7128 is a CB1 receptor inverse agonist.Formula:C29H25ClF2N4O2Color and Shape:SolidMolecular weight:534.98(-)-Adenophorine
CAS:(-)-Adenophorine is a moderate alpha-l-fucosidase inhibitor.Formula:C8H17NO4Color and Shape:SolidMolecular weight:191.22SB-612111 hydrochloride
SB-612111 is a potent ORL-1 antagonist, with high affinity (Ki: 0.33 nM) and µ-receptor activity (Ki: 57.6 nM), blocking Nociceptin-induced pain.Formula:C24H30Cl3NOColor and Shape:SolidMolecular weight:454.86Topo I-IN-1
Topo I-IN-1 (14d) is a powerful Topo I inhibitor with antitumor effects and DNA intercalation, inducing apoptosis.Formula:C20H14BrN3O2Color and Shape:SolidMolecular weight:408.25IRAK4-IN-14
CAS:IRAK4-IN-14 is a selective, potent, orally active IRAK4 inhibitor (IC50: 0.003 μM) with favorable PK parameters in rats and mice. effect.Formula:C25H28FN9OColor and Shape:SolidMolecular weight:489.55IL-17 modulator 1 disodium
CAS:Potent, orally active IL-17 Modulator 1 (disodium) from patent WO 2020127685, used in psoriasis and arthritis research.Formula:C28H37N6NaO6PColor and Shape:SolidMolecular weight:607.604(S)-MALT1-IN-5
CAS:(S)-MALT1-IN-5: Potent MALT1 protease inhibitor, may help in abnormal T/B-cell signalling and MALT1-linked diseases.Formula:C17H17ClF2N6O3Color and Shape:SolidMolecular weight:426.80CREB-IN-1 TFA
CREB-IN-1 TFA: Potent oral CREB inhibitor, IC50 of 0.18 μM, suppresses breast cancer cell growth.Color and Shape:SolidWW437
WW437 is a histone deacetylase (HDAC) inhibitor that exhibits potent anti-breast cancer activity both in vitro and in vivo.Formula:C23H27N5O4Color and Shape:SolidMolecular weight:437.49Ambelline
CAS:Ambelline has antitumor activity.Formula:C18H21NO5Purity:98%Color and Shape:SolidMolecular weight:331.36Sekdel sequence
CAS:Sekdel sequence, as a signal, leads to retention of at least two proteins in the endoplasmic reticulum of animal cells.Formula:C29H49N7O14Color and Shape:SolidMolecular weight:719.74AA 497 (Free Base)
CAS:AA 497, a beta-2 agonist, causes relaxation and suppresses Ca spike frequency.Formula:C14H21NO3Purity:98%Color and Shape:SolidMolecular weight:251.32TrxR-IN-2
TrxR-IN-2 is a potential thioredoxin reductase (TrxR) inhibitor. TrxR-IN-2 has research value in the chemotherapy of drug-resistant hepatocellular carcinoma.Formula:C22H22N4O4Color and Shape:SolidMolecular weight:406.43KRAS G12D inhibitor 9
CAS:KRAS G12D inhibitor 9 targets RAS protein, key in growth, showing promise against KRAS G12D cancer.Formula:C33H43N7O2Color and Shape:SolidMolecular weight:569.74Dicetrorelix pamoate
CAS:Cetrorelix pamoate is a synthetic decapeptide that acts as a GnRH antagonist, inhibiting the release of LH and FSH from the pituitary.Formula:C163H200Cl2N34O34Color and Shape:SolidMolecular weight:3250.49COX-2/PI3K-IN-1
COX-2/PI3K-IN-1 (compound 5d) is a potent inhibitor of PI3K (IC50: 1.14 nM). COX-2/PI3K-IN-1 is a selective inhibitor of COX-2 (Ki: 3.24 nM).Formula:C19H14ClN5S2Color and Shape:SolidMolecular weight:411.93LLS30
CAS:LLS30 inhibits Gal-1, reduces its binding affinity, and may help treat advanced prostate cancer.Formula:C34H33Cl4N5O3Color and Shape:SolidMolecular weight:701.47UB 165
CAS:Subtype-selective nicotinic agonistFormula:C13H15ClN2Purity:98%Color and Shape:SolidMolecular weight:234.72BF-168
CAS:BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).Formula:C18H17FN2O2Color and Shape:SolidMolecular weight:312.34ATM-3507 trihydrochloride (1861449-70-8 free base)
ATM-3507 trihydrochloride is a potent tropomyosin inhibitor (IC50s: 3.83-6.84 μM in human melanoma cell lines).Formula:C37H49Cl3FN5O2Purity:98%Color and Shape:SolidMolecular weight:721.17D18
CAS:D18: Dual agonist for TLR7/8, boosts PD-L1, aids tumor sensitivity to PD-1/PD-L1 inhibitors, and is a cytotoxin for ADC HE-S2.Formula:C21H28N6Color and Shape:SolidMolecular weight:364.49Anticancer agent 44
Anticancer agent 44 induces apoptosis, is selective, cytotoxic to cancer cells, and minimally toxic to human lymphocytes.Formula:C22H13Cl2N3O5S2Color and Shape:SolidMolecular weight:534.39Netupitant metabolite Monohydroxy Netupitant
CAS:Monohydroxy Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite.Formula:C30H32F6N4O2Purity:98%Color and Shape:SolidMolecular weight:594.59MK-8970
MK-8970 is an acetal carbonate prodrug of raltegravir with enhanced colonic absorption.Formula:C25H29FN6O8Color and Shape:SolidMolecular weight:560.54MRTX849 ethoxypropanoic acid
CAS:MRTX849 is a KRAS G12C ligand and PROTAC linker for creating potent LC-2, degrading KRAS G12C with DC50 of 0.25-0.76 μM.Formula:C37H43ClFN7O5Color and Shape:SolidMolecular weight:720.24IDO1-IN-13
IDO1-IN-13 is a potent IDO1 inhibitor (IC50: 61.6 nM, EC50: 30 nM in HeLa) that reduces kyn/trp ratio by 51% in SK-OV-3 tumors.Formula:C20H16BrN5O2SColor and Shape:SolidMolecular weight:470.34NF-κB-IN-4
NF-κB-IN-4 (compound 17) is a potent inhibitor of NF-κB pathway which can cross blood brain barrier (BBB).Formula:C18H15FN4OColor and Shape:SolidMolecular weight:322.34rel-MDM2/4-p53-IN-2
Potent dual MDM2/MDM4 inhibitor & p53 activator; IC50: 70.7 nM (MDM2), 81.4 nM (MDM4); regulates cell cycle, triggers apoptosis, anti-cancer.Formula:C25H17Cl3FN3O3Color and Shape:SolidMolecular weight:532.78OSI-7904L free acid
CAS:OSI-7904L is a folate-based thymidylate synthase inhibitor. It also has antimalarial and antitumor properties.Formula:C27H24N4O6Purity:98%Color and Shape:SolidMolecular weight:500.5L 691816
CAS:L 691816 is an effective inhibitor of the 5-LO reaction.Formula:C36H35ClN6OSPurity:98%Color and Shape:SolidMolecular weight:635.22KH-259
KH-259: potent, selective CNS-penetrant HDAC6 inhibitor with 0.26 μM IC50; shows antidepressant effects in mice.Formula:C20H25N3O2Color and Shape:SolidMolecular weight:339.43KFA1982
CAS:KFA1982 is a novel and potent factor Xa inhibitor.Formula:C28H34ClN3O9S2Color and Shape:SolidMolecular weight:656.17(25S)-δ7-Dafachronic acid
CAS:(25S)-delta7-Dafachronic acid, an orphan nuclear receptor DAF-12 ligand, inhibits the dauer-promoting activity of DAF-12.Formula:C27H42O3Purity:98%Color and Shape:SolidMolecular weight:414.62(R)-CSN5i-3
CAS:(R)-CSN5i-3 is CSN5i-3 of the R configuration.Formula:C28H29F2N5O2Purity:99.76% - 99.97%Color and Shape:SolidMolecular weight:505.56Antifungal agent 19
Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).Formula:C19H18F4O2Color and Shape:SolidMolecular weight:354.34LolCDE-IN-2
CAS:LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].Formula:C22H17N5OPurity:98%Color and Shape:SolidMolecular weight:367.40DHFR-IN-4
CAS:DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with anti-tumour activity, inhibits EGFR and HER2 and can be used to study pancreatic cancer.Formula:C18H21N5O2SPurity:99.41%Color and Shape:SolidMolecular weight:371.46MrgprX2 antagonist-6
MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation.Formula:C24H23F3N6O3Color and Shape:SolidMolecular weight:500.47MCTR2
CAS:MCTR2, synthesized from DHA in macrophages, aids in tissue repair and reduces inflammation by promoting eicosanoid PGD2 and PGF2α decrease.Formula:C27H40N2O6SColor and Shape:SolidMolecular weight:520.68SB-612111
CAS:SB-612111: potent ORL-1 antagonist, Ki=0.33 nM; μ-, κ-, δ-receptor Ki=57.6, 160.5, 2109 nM; blocks nociceptin's pain effect.Formula:C24H29Cl2NOColor and Shape:SolidMolecular weight:418.40Antioxidant agent-8
Antioxidant agent-8, an oral Aβ 1-42 inhibitor, reduces fibril aggregation & promotes disaggregation; it's neuroprotective & BBB permeable.Formula:C13H12O5Color and Shape:SolidMolecular weight:248.23Anticancer agent 80
Anticancer agent 80 (Compound 3c) is an anticancer agent that exhibits a significant dark toxic effect on T47-D (IC50: 10.14 μM).Formula:C19H12BrNO5Color and Shape:SolidMolecular weight:414.21BMS 310705
CAS:BMS 310705, an Epothilone B analog, targets ovarian/renal/bladder/lung cancer, inducing apoptosis via mitochondria.Formula:C27H42N2O6SColor and Shape:SolidMolecular weight:522.70TCMDC-125431
TCMDC-125431 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystals.Formula:C25H27N3O2SColor and Shape:SolidMolecular weight:433.57LSD1/ER-IN-1
LSD1/ER-IN-1 inhibits ER & LSD1 (IC50: 1.55 μM), and fights MCF-7 breast cancer (IC50: 8.79 μM).Formula:C23H18FNO6SColor and Shape:SolidMolecular weight:455.46L-threo-Sphingosine C-18
CAS:L-threo-Sphingosine C-18 is a protein kinase C inhibitor.Formula:C18H37NO2Purity:98%Color and Shape:SolidMolecular weight:299.49Anti-inflammatory agent 16
Compound 14 is a peptidomimetic that significantly lowers TNFα, NO, CD40, and CD86, showcasing strong anti-inflammatory effects.Formula:C21H23N5O3Color and Shape:SolidMolecular weight:393.44Calphostin I
CAS:Calphostins, from Cladosporium fungus, inhibit PKC. Notably, calphostin C is a potent biochemical tool.Formula:C44H38O15Color and Shape:SolidMolecular weight:806.76FTO-IN-1 TFA
FTO-IN-1 TFA: FTO enzyme inhibitor, anti-obesity, IC50 < 1μM, potential cancer research tool.Formula:C20H17Cl2F3N4O4Color and Shape:SolidMolecular weight:505.27
