Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,833 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,612 products)
- Cytoskeletal Signaling(1,566 products)
- DNA Damage/DNA Repair(2,872 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,900 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,139 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,369 products)
- Other Inhibitors(35,852 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,430 products)
- Proteases/Proteasome(1,691 products)
- Stem Cell and Derivatives(733 products)
- Tyrosine Kinase/Adaptors(1,983 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
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BSc5367
CAS:BSc5367 inhibits Nek1 kinase (IC50: 11.5 nM), key in cell cycle, DNA repair, impacting ALS, PKD, cancer.
Formula:C20H15N3O2Color and Shape:SoildMolecular weight:329.35CYP11B1-IN-2
CYP11B1-IN-2 selectively inhibits human and rat CYP11B1 (IC50: 9/25 nM) orally to research cortisol-related diseases.Color and Shape:SolidPS-519
CAS:PS-519 is a human tissue plasminogen activator and proteasome inhibitor.Formula:C12H19NO4Color and Shape:SolidMolecular weight:241.28O-GlcNAcase-IN-1
O-GlcNAcase-IN-1 is a potent and novel inhibitor of O-GlcNAcase(OGA) with an IC 50 value of 46 nM.Formula:C15H22N6Color and Shape:SolidMolecular weight:286.38DHU-Se1
DHU-Se1: potent anti-inflammatory, releases reactive selenium from macrophages, inhibits iNOS/TNF-α, blocks M0 to M1 polarization.Formula:C23H23N3OSSeColor and Shape:SolidMolecular weight:468.47sEH inhibitor-1
TCPU (sEH inhibitor-1) is a potent oral human sEH blocker with IC50s of 0.4 nM (human) and 5.3 nM (mouse).
Color and Shape:SolidART615
ART615 is a related isomer of ART558. ART615 inhibits Polθ by <10% at 12 μM and is able to act as a control for ART558 (IC50:7.9 nM).Formula:C21H21F3N4O2Color and Shape:SolidMolecular weight:418.41Saussureamine C
CAS:Saussureamine C is an inhibitor of H274Y and N294S mutants.Formula:C19H26N2O5Color and Shape:SolidMolecular weight:362.42P-gp modulator 2
P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic P-glycoprotein (P-gp) modulator.Formula:C22H20BrN3O4Color and Shape:SolidMolecular weight:470.32HDAC-IN-35
HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.Formula:C17H13ClF3N3O3Color and Shape:SolidMolecular weight:399.75RN941
CAS:RN941 is a highly potent Bruton's tyrosine kinase (BTK) inhibitor.Formula:C34H34FN7O5Purity:98%Color and Shape:SolidMolecular weight:639.68STA-1474
CAS:STA-1474, a soluble prodrug of ganetespib (STA-9090), becomes a strong HSP90 inhibitor effective against canine tumors.Formula:C20H21N4O6PColor and Shape:SolidMolecular weight:444.38Nonsteroidal aromatase inhibitor 1
Compound 13h, a nonsteroidal aromatase inhibitor, has a potent IC50 of 0.09 nM against CYP19A1, showing promise for breast cancer research.Formula:C22H16N4O2Color and Shape:SolidMolecular weight:368.39AZD4625
AZD4625 (Compound 21) is a selective, potent, orally active, covalent and mutagenic mutant GTPaseKRASG12C inhibitor.Formula:C24H21ClF2N4O3Color and Shape:SolidMolecular weight:486.9Indoluidin E
Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.Formula:C28H30N4O2Color and Shape:SolidMolecular weight:454.56ZIKV-IN-5
ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.Formula:C36H45NO4SiColor and Shape:SolidMolecular weight:583.83FGFR-IN-6
CAS:FGFR-IN-6 (Compound 5) is an FGFR inhibitor.Formula:C23H22N6O3Color and Shape:SolidMolecular weight:430.46Ambuic acid
CAS:Ambuic acid: cyclohexanone with antifungal, quorum-inhibiting, antibacterial properties, blocks cyclic peptides; reduces MRSA abscesses in mice.Formula:C19H26O6Color and Shape:SolidMolecular weight:350.41AZ0108
CAS:AZ0108, an oral PARP1,2,6 inhibitor, selectively blocks centrosome clustering, is viable for in vivo studies, and doesn't inhibit PARP3/TNKS1.Formula:C24H20F4N6O2Color and Shape:SolidMolecular weight:500.45UK-432097
CAS:UK 432097 is an adenosine A2A agonist.Formula:C40H47N11O6Color and Shape:SolidMolecular weight:777.87GNTI TFA
CAS:GNTI TFA is a selective kappa opioid receptor antagonist.Formula:C31H31F6N5O7Color and Shape:SolidMolecular weight:699.60PLAP-IN-1
CAS:PLAP-IN-1: Potent, selective inhibitor of PLAP, IC50 of 32 nM; doesn't notably inhibit TNAP.Formula:C25H21Cl2N3O5Color and Shape:SoildMolecular weight:514.36P-gp/BCRP-IN-1
CAS:P-gp/BCRP-IN-1, safe and oral, inhibits P-gp/BCRP transporters, enhancing Paclitaxel bioavailability.Formula:C27H25ClN4O3Color and Shape:SolidMolecular weight:488.97Calphostin A
CAS:Calphostins, from Cladosporium fungus, inhibit PKC; calphostin C is most potent, used as a biochemical tool.Formula:C44H38O12Color and Shape:SolidMolecular weight:758.77LP-284
CAS:LP-284 is a DNA alkylating agent effective against solid tumors and hematologic cancers like MCL.Formula:C16H20N2O4Color and Shape:SolidMolecular weight:304.34CDK1-IN-5
CDK1-IN-5 is a selective inhibitor for CDK1 (IC50: 42.19 nM), CDK2, CDK5, halting cancer cell growth.Formula:C27H26ClN5OSColor and Shape:SolidMolecular weight:504.05Geissoschizoline
CAS:Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.Formula:C19H26N2OColor and Shape:SolidMolecular weight:298.42SLC4011540
SLC4011540 is a potent and selective SphK1/2 dual inhibitor with Ki value of 120 nM and 90 nM respectively.Formula:C24H23ClF3N7OSColor and Shape:SolidMolecular weight:550FTI 276 TFA
CAS:FTI 276 TFA targets plasmodium falciparum & humans, inhibits PFT with IC50s: 0.9 nM (parasite) & 0.5 nM (human).Formula:C23H28F3N3O5S2Color and Shape:SolidMolecular weight:547.6114α-Demethylase/DNA Gyrase-IN-1
14α-Demethylase/DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.Formula:C26H22N4O4Color and Shape:SolidMolecular weight:454.48CLK1/4-IN-1
CLK1/4-IN-1 inhibits Clk1/4 (IC50: 9.7/6.6 nM), curbing T24 cell growth (GI50: 1.1 μM). Potential cancer research tool.Formula:C18H14ClNO4SColor and Shape:SolidMolecular weight:375.83Microtubule inhibitor 2
Microtubule inhibitor 2: potent, selective, oral, induces ferroptosis, strong antitumor effect.Formula:C20H23NO7Color and Shape:SolidMolecular weight:389.4Emd 52297
CAS:Emd 52297 is an inhibitor of renin.Formula:C39H59N11O7Purity:98%Color and Shape:SolidMolecular weight:793.96DC-U4106
CAS:DC-U4106: USP8 inhibitor, Kd 4.7μM, IC50 1.2μM, degrades Erα, low-toxicity tumor suppressor for breast cancer research.Formula:C29H27N5O5Color and Shape:SolidMolecular weight:525.56SOS1-IN-10
SOS1-IN-10 is a potent inhibitor of SOS1 that acts on KRAS G12C-SOS1 (IC50: 13 nM).Formula:C22H19F5N4OColor and Shape:SolidMolecular weight:450.4METTL3-IN-3
CAS:METTL3-IN-3 is a polyheterocyclic compound, acts as METTL3 inhibitor .Formula:C26H28BrFN6O2Color and Shape:SolidMolecular weight:555.44KPC-2-IN-2
KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.Formula:C12H10BN3O2SColor and Shape:SolidMolecular weight:271.1PI3kδ inhibitor 1
CAS:PI3kδ inhibitor 1 is a selective inhibitor of PI3Kδ (IC50 of 3.8 nM).Formula:C28H33FN6O2Purity:98%Color and Shape:SolidMolecular weight:504.60MB-07344 sodium
"MB-07344 sodium is a TR-β agonist with a 2.17 nM Ki, boosts Atorvastatin's cholesterol-lowering effects in various animals."Formula:C19H25NaO5PPurity:98%Color and Shape:SolidMolecular weight:387.36YM 202074
CAS:metabotropic glutamate receptor type 1 (mGlu1) antagonistFormula:C56H72N8O16S2Purity:98%Color and Shape:SolidMolecular weight:1177.34PARP10/15-IN-1
PARP10/15-IN-1 (compound 8l) is a dual PARP10 and PARP15 inhibitor with IC50s of 160 nM and 370 nM, respectively. It can be used in cancer research[1].Formula:C13H10N2O3SColor and Shape:SolidMolecular weight:274.3OPC-167832
CAS:OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.Formula:C21H20ClF3N2O4Color and Shape:SolidMolecular weight:456.84Protease-Activated Receptor-1 antagonist 2
Selective, orally active PAR-1 antagonist with an IC50 of 7 nM, potential for cardiovascular disease studies.Color and Shape:SolidnNOS-IN-25
CAS:nNOS-IN-25 is an effective, selective, and cell-permeable inhibitor of neuronal nitric oxide synthase.Formula:C21H22N4Purity:98%Color and Shape:SolidMolecular weight:330.43TEI-9063
CAS:TEI-9063 is a stable and highly specific prostacyclin analogue of prostacyclin receptor in mast cell tumor p-815 cells.Formula:C23H38O4Color and Shape:SolidMolecular weight:378.55BMS-901715
CAS:BMS-901715 is an effective and selective inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50: 3.3 nM).Formula:C22H28N10OPurity:98%Color and Shape:SolidMolecular weight:448.52JAK-2/3-IN-3
JAK-2-/3-IN-3 (ST4j) is a potent JAK2/3 inhibitor for leukemia research, with IC50s: JAK2, 13 nM; JAK3, 14.86 nM; induces apoptosis.Formula:C13H10Cl2N4O2Color and Shape:SolidMolecular weight:325.15MTL-CEBPA
MTL-CEPBA is a small activating RNA that targets C/EBPα upregulation and exhibits anti-inflammatory and anti-cancer effects.Color and Shape:SolidKDOAM-25 citrate
CAS:KDOAM-25 citrate inhibits KDM5A/B/C/D (IC50: 71, 19, 69, 69 nM); boosts H3K4 methylation, hinders MM1S cell growth. [1]Formula:C21H33N5O9Purity:98%Color and Shape:SolidMolecular weight:499.51Elongation factor P-IN-1
EFP-IN-1: potent β-lysine derivative, inhibits EFP, slows E. coli growth.Formula:C14H31N3O2Color and Shape:SolidMolecular weight:273.41
