Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,749 products)
- Apoptosis(6,182 products)
- Cell Cycle/Checkpoint(4,805 products)
- Chromatin/Epigenetics(2,571 products)
- Cytoskeletal Signaling(1,499 products)
- DNA Damage/DNA Repair(2,896 products)
- Endocrinology/Hormones(3,702 products)
- Enzyme(3,671 products)
- GPCR/G-Protein(8,962 products)
- Immunology and Inflammation(3,694 products)
- Influenza Virus(296 products)
- JAK/STAT signaling(414 products)
- MAPK Signaling(1,246 products)
- Membrane Transporter/Ion Channel(3,135 products)
- Metabolism(10,102 products)
- Microbiology/Virology(7,552 products)
- Neuroscience(10,303 products)
- Other Inhibitors(35,763 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,400 products)
- Proteases/Proteasome(1,670 products)
- Stem Cell and Derivatives(742 products)
- Tyrosine Kinase/Adaptors(1,922 products)
- Ubiquitination(1,715 products)
Show 16 more subcategories
Found 66575 products of "Inhibitors"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
LY309887
CAS:LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.Formula:C19H23N5O6SColor and Shape:SolidMolecular weight:449.48LY3130481
CAS:LY3130481: TARP γ-8 dependent AMPA receptor blocker; selectively targets AMPA/TARP γ-8 with 65 nM IC50.Formula:C19H18N4O3SColor and Shape:SolidMolecular weight:382.44MRS4738
MRS4738 is a potent antagonist with high affinity for the P2Y14R receptor. It demonstrates in vivo anti-hyperallodynic and antiasthmatic activity [1].Formula:C30H24F3NO2Color and Shape:SolidMolecular weight:487.51ZK168281
CAS:ZK168281 is a 1α,25(OH)2D3 analog, VDR antagonist with 0.1 nM Kd, and blocks receptor CoA interaction.Formula:C32H46O5Purity:98%Color and Shape:SolidMolecular weight:510.70Enpp-1-IN-12
ENPP1-IN-12 is a potent, oral ENPP1 inhibitor with a Ki of 41 nM and anti-tumor properties.Formula:C17H19N5O3SColor and Shape:SolidMolecular weight:373.43Alkyne-probe 1
Alkyne-probe 1 is usually used as an Alkyne-labeled fluorescent or chemical probe.Formula:C14H23N5O2Purity:98%Color and Shape:SolidMolecular weight:293.36FNDR-20123
FNDR-20123: First safe, effective anti-malarial HDAC inhibitor for Plasmodium (IC50: 31 nM) & human HDACs, with nanomolar potency across several subtypes.Formula:C21H24ClN5O2Color and Shape:SolidMolecular weight:413.9Zorubicin
CAS:Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.Formula:C34H35N3O10Color and Shape:SolidMolecular weight:645.66WEHI-539
CAS:WEHI-539 is a selective Bcl-XL inhibitor (IC50: 1.1 nM).Formula:C31H29N5O3S2Purity:98%Color and Shape:SolidMolecular weight:583.72Taprostene
CAS:Taprostene (CG-4203), a stable Prostacyclin analogue, protects endothelium and myocardium post-ischemia in cats, with minimal hemodynamic impact.Formula:C24H30O5Color and Shape:SolidMolecular weight:398.49D-473
CAS:D-473 is a novel orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.
Formula:C26H27F2NO3Color and Shape:SolidMolecular weight:439.49Bizelesin
CAS:Bizelesin, a synthetic antineoplastic agent, binds DNA, disrupts replication, triggers cell-cycle arrest, and induces senescence.Formula:C43H36Cl2N8O5Color and Shape:SolidMolecular weight:815.7MDL-28050
CAS:MDL-28050 is a synthetic analog of hirudin 55-65 C-terminal fragment and a peptide inhibitor.Formula:C61H88N10O23Color and Shape:SolidMolecular weight:1329.4RGT-068A
CAS:RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor .Formula:C17H16ClN9O2Color and Shape:SolidMolecular weight:413.82RTIOX-372
CAS:RTIOX-372 is a potent and selective orexin-1 receptor antagonist.Formula:C30H39N5O3Color and Shape:SolidMolecular weight:517.66Antibiotic MA 144M1
CAS:Antibiotic MA 144M1, an anthracycline, targets gram-positive bacteria and animal tumors; derived from Streptomyces fermentation or aclacinomycin A conversion.Formula:C42H55NO15Color and Shape:SolidMolecular weight:813.88HIV-1 inhibitor-8
HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.Formula:C25H21N5OSColor and Shape:SolidMolecular weight:439.53CDK1-IN-3
CDK1-IN-3 is a selective inhibitor targeting CDK1 (36.8 nM), CDK2 (305.17 nM), CDK5 (369.37 nM); used in cancer research.Formula:C28H25ClF3N5O2Color and Shape:SolidMolecular weight:555.98Antitubercular agent-16
Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.Formula:C21H27N3SColor and Shape:SolidMolecular weight:353.52GSD-11
GSD-11: Potent, selective anti-austerity agent; blocks Akt/mTOR pathway, hinders PANC-1 cell migration & colony growth. Promising for pancreatic cancer study.Formula:C20H28O2Color and Shape:SolidMolecular weight:300.44IL-17 modulator 5
CAS:IL-17 modulator 5 is a IL-17 inhibitor, with an IC 50 of 1 nM .Formula:C28H23F6N9O2Color and Shape:SolidMolecular weight:631.53Uprosertib hydrochloride
CAS:Uprosertib hydrochloride is a potent and selective inhibitor of pan-Akt (IC50: 180/328/38 nM for Akt1/Akt2/Akt3, respectively).Formula:C18H17Cl3F2N4O2Purity:98%Color and Shape:SolidMolecular weight:465.71Gallinamide A
CAS:Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.Formula:C31H52N4O7Color and Shape:SolidMolecular weight:592.77FXIa-6f
CAS:FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical speciesFormula:C31H29ClF2N4O4Color and Shape:SolidMolecular weight:595.04PHGDH-IN-2
PHGDH-IN-2: potent PHGDH inhibitor, IC50=5.2μM; hinders PHGDH cancer cell growth & serine synthesis in MDA-MB-468.Formula:C22H20N4O3SColor and Shape:SolidMolecular weight:420.48Lometrexol disodium
CAS:Lometrexol disodium: Inhibits hSHMT1/2 and GARFT, anticancer by blocking purine synthesis, induces apoptosis and cell cycle arrest.Formula:C21H23N5Na2O6Color and Shape:SolidMolecular weight:487.424U 75875
CAS:U 75875 is a protease inhibitor.Formula:C45H61N7O7Color and Shape:SolidMolecular weight:812.01AD5075
CAS:AD5075 is a bioactive chemical.Formula:C22H20N2O5SColor and Shape:SolidMolecular weight:424.47Difeterol
CAS:Difeterol is a biochemical.Formula:C25H29NO2Color and Shape:SolidMolecular weight:375.50Aristoforin
CAS:Aristoforin is a SIRT1 and SIRT2 inhibitor that induces cell cycle arrest, shows potent antitumor effects, and inhibits lymphangiogenesis in vivo.Formula:C37H54O6Color and Shape:SolidMolecular weight:594.82Etamicastat
CAS:Etamicastat can be used in the research of cardiovascular diseases.Formula:C14H15F2N3OSPurity:98%Color and Shape:SolidMolecular weight:311.35MDL-100240
CAS:MDL-100240 inhibits ACE/neprilysin, effective against hypertension-induced heart/vascular changes.Formula:C26H28N2O5SPurity:98%Color and Shape:SolidMolecular weight:480.58TLR7/8 antagonist 2
TLR7/8 antagonist 2: potent, orally active, IC50: 4.9 nM (TLR7), 0.6 nM (TLR8); potential for lupus therapy research.Formula:C22H26FN5Color and Shape:SolidMolecular weight:379.47MtTMPK-IN-1
MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.Formula:C22H24N4O3Color and Shape:SolidMolecular weight:392.45NITD-688
CAS:NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.Formula:C25H32N4O3S2Color and Shape:SolidMolecular weight:500.68TGR5 Receptor Agonist 3
CAS:TGR5 Receptor Agonist 3 is a GPBAR1 agonist with EC50 of 16.4 nM (hTGR5) & 209 nM (mTGR5), ensures gallbladder safety and reduces filling.Formula:C29H27N3O6Color and Shape:SolidMolecular weight:513.54MDL-27088
CAS:MDL-27088 is an angiotensin-covering enzyme inhibitor.Formula:C25H28N2O5Color and Shape:SolidMolecular weight:436.50HR-546
CAS:HR-546 is a prostaglandin E2 and prostaglandin F2alpha antagonist.Formula:C26H44O6Color and Shape:SolidMolecular weight:452.6218-Deoxyherboxidiene
CAS:18-Deoxyherboxidiene (RQN-18690A) inhibits angiogenesis, targeting SF3b in U2 snRNP spliceosome, affects HUVEC, useful for cancer research.Formula:C25H42O5Color and Shape:SolidMolecular weight:422.6BAY-850 HCl
BAY-850 is a selective probe targeting Atad2A's bromine domain, displacing acetylated H4 peptides and detaching ATAD2 from chromatin at 1μm.Formula:C38H48Cl5N5O3Color and Shape:SolidMolecular weight:800.08Kolavenic acid analog
CAS:KAA, an anticancer compound, inhibits centrosome clustering and targets HSET+ yeast and cancer cells.Formula:C25H38O4Color and Shape:SolidMolecular weight:402.57TA-316
CAS:Agent induces megakaryocytes/platelets from stem cells to treat thrombopenia.Formula:C28H25BrN4O5S2Purity:98%Color and Shape:SolidMolecular weight:641.56Epiderstatin
CAS:Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.Formula:C15H20N2O4Color and Shape:SolidMolecular weight:292.33URAT1 inhibitor 2
URAT1 inhibitor 2: oral URAT1/CYP blocker, IC50 of 1.36μM (URAT1), 16.97μM (CYP1A2), 5.22μM (CYP2C9); potential gout treatment.Formula:C21H18BrN3O2SColor and Shape:SolidMolecular weight:456.36Antioxidant agent-8
Antioxidant agent-8, an oral Aβ 1-42 inhibitor, reduces fibril aggregation & promotes disaggregation; it's neuroprotective & BBB permeable.Formula:C13H12O5Color and Shape:SolidMolecular weight:248.23SB-612111
CAS:SB-612111: potent ORL-1 antagonist, Ki=0.33 nM; μ-, κ-, δ-receptor Ki=57.6, 160.5, 2109 nM; blocks nociceptin's pain effect.Formula:C24H29Cl2NOColor and Shape:SolidMolecular weight:418.40SID 26681509 quarterhydrate
SID 26681509 is a selective inhibitor of cathepsin L (IC50: 56 nM) and blocks Plasmodium falciparum (IC50: 15.4 μM) and Leishmania major (IC50: 12.5 μM).Formula:C27H35N5O6SColor and Shape:SolidMolecular weight:544.16MRTX849 ethoxypropanoic acid
CAS:MRTX849 is a KRAS G12C ligand and PROTAC linker for creating potent LC-2, degrading KRAS G12C with DC50 of 0.25-0.76 μM.Formula:C37H43ClFN7O5Color and Shape:SolidMolecular weight:720.24TrxR-IN-2
TrxR-IN-2 is a potential thioredoxin reductase (TrxR) inhibitor. TrxR-IN-2 has research value in the chemotherapy of drug-resistant hepatocellular carcinoma.Formula:C22H22N4O4Color and Shape:SolidMolecular weight:406.43DL-Buthionine-(S,R)-sulfoximine hydrochloride
DL-Buthionine-(S,R)-sulfoximine hydrochloride (Buthionine sulfoximine hydrochloride) is a potent and specific glutamylcysteine synthetase biosynthesis inhibitorFormula:C8H19ClN2O3SColor and Shape:SolidMolecular weight:258.77
