Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,795 products)
- Apoptosis(6,256 products)
- Cell Cycle/Checkpoint(4,836 products)
- Chromatin/Epigenetics(2,591 products)
- Cytoskeletal Signaling(1,534 products)
- DNA Damage/DNA Repair(2,880 products)
- Endocrinology/Hormones(3,748 products)
- Enzyme(3,670 products)
- GPCR/G-Protein(8,982 products)
- Immunology and Inflammation(3,789 products)
- Influenza Virus(299 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,250 products)
- Membrane Transporter/Ion Channel(3,148 products)
- Metabolism(10,143 products)
- Microbiology/Virology(7,591 products)
- Neuroscience(10,344 products)
- Other Inhibitors(35,823 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,420 products)
- Proteases/Proteasome(1,680 products)
- Stem Cell and Derivatives(748 products)
- Tyrosine Kinase/Adaptors(1,958 products)
- Ubiquitination(1,720 products)
Show 16 more subcategories
Found 66564 products of "Inhibitors"
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Bcl-2-IN-8
Bcl-2-IN-8: potent, hinders cell growth/migration, induces apoptosis, promising in triple-negative breast cancer research.Formula:C36H44O6Color and Shape:SolidMolecular weight:572.73Ro-51
CAS:dual P2X3 and P2X2/3 antagonistFormula:C17H23IN4O4Purity:98%Color and Shape:SolidMolecular weight:474.29Antibacterial agent 62
Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.Formula:C24H33BrN2O2Color and Shape:SolidMolecular weight:461.44Urease-IN-1
Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).Formula:C17H12BrFN4O2SColor and Shape:SolidMolecular weight:435.27TS010
TS010 is a highly potent inhibitor of GLO-I, with an IC50 value of 0.57 μM. It holds significant promise for advancements in cancer research [1].Formula:C16H12N4O4SColor and Shape:SolidMolecular weight:356.36Antimalarial agent 9
Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.Formula:C28H32BrN3O2Color and Shape:SolidMolecular weight:522.48Carbonic anhydrase inhibitor 8
R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5HS-731
CAS:HS-731 is a μ-Opioid Receptor Agonist.Formula:C20H26N2O5Color and Shape:SolidMolecular weight:374.43Lasonolide A
CAS:Lasonolide A, an anticancer compound from Forcepia sponge, shows nanomolar growth inhibition and unique cytotoxicity in the NCI 60-cell-line screen.Formula:C41H60O9Color and Shape:SolidMolecular weight:696.91ZLMT-12
ZLMT-12: tacrine derivative, inhibits CDK2/CDK9, weak on AChE/BuChE, anti-proliferative, low toxicity, blocks S/G2/M phase, induces apoptosis.Formula:C26H31ClN6OColor and Shape:SolidMolecular weight:479.02ACT-672125
CAS:ACT-672125: Potent CXCR3 blocker, may treat autoimmunity, safe with dose-dependent efficacy in lung inflammation.Formula:C25H25F3N10O2SColor and Shape:SolidMolecular weight:586.59LSD1-IN-16
LSD1-IN-16 (4b) inhibits LSD1, MAO-A/B; IC50: 0.015-0.366 μM. Halts prostate cancer cell growth; IC50: 15.2 μM.Formula:C20H18N2OSColor and Shape:SolidMolecular weight:334.43Glutaminyl Cyclase Inhibitor 3
CAS:Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.Formula:C24H32N6O2SPurity:98%Color and Shape:SolidMolecular weight:468.61CDK/HDAC-IN-1
CDK/HDAC-IN-1 inhibits CDK2/4/6 & HDAC6 with IC50s: 60.9, 276, 27.2, and 128.6 nM respectively.Formula:C20H18N4O4Color and Shape:SolidMolecular weight:378.38AM-3189
CAS:AM-3189: potent, selective GPR40 agonist with low CNS penetration, good pharmacokinetics, and efficacy mirroring AMG 837.Formula:C27H25ClN2O3Color and Shape:SolidMolecular weight:460.95Antibacterial agent 75
Antibacterial agent 75 re-sensitizes VRSA to vancomycin.Formula:C22H28N6OColor and Shape:SolidMolecular weight:392.5GPR81 agonist 2
CAS:GPR81 agonist 2 is a potent agonist targeting the GPR81 receptor, demonstrating EC50 values of 0.023 µM for hGPR81 and 0.123 µM for hGPR109A, respectively.Formula:C26H27ClN6O5S2Color and Shape:SolidMolecular weight:603.11hCA IX-IN-1
hCA IX-IN-1 inhibits human carbonic anhydrases I, II, IX, and XII with Ki values of 331.4, 28.4, 9.4, 17.8 nM and exhibits anticancer properties.Formula:C19H18N2O3SColor and Shape:SolidMolecular weight:354.42Omesdafexor
CAS:Omesdafexor is an FXR agonist that can be used to study diseases caused by liver disease or metabolic inflammation.Formula:C34H43N3O3Color and Shape:SolidMolecular weight:541.72Mal-PEG4-VA-PBD
CAS:Mal-PEG4-VA-PBD is a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), comprising the antitumor antibiotic Pyrrolobenzodiazepine (PBD), connectedFormula:C68H79N9O17Purity:98%Color and Shape:SolidMolecular weight:1294.41Indoluidin E
Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.Formula:C28H30N4O2Color and Shape:SolidMolecular weight:454.56ATM Inhibitor-3
ATM Inhibitor-3 selectively inhibits ATM (IC50: 0.71 nM), targets PI3K kinase family, and is metabolically stable.Formula:C25H29FN6O3Color and Shape:SolidMolecular weight:480.53Icariside F2
CAS:Icariside F2 modestly inhibits α-glucosidase (4.6-12%) and has antioxidant properties, plus strong NF-κB inhibition (IC50: 16.25±2.19 μM).Formula:C18H26O10Purity:98%Color and Shape:SolidMolecular weight:402.39CCR7 Ligand 1
CAS:CCR7-Cmp2105 is a thiadiazole-dioxide allosteric antagonist for CCR7 with a Kd of 3 nM and IC50 of 7.3 μM against arrestin binding.Formula:C22H29N5O5SColor and Shape:SolidMolecular weight:475.56HDAC/HSP90-IN-4
HDAC/HSP90-IN-4 inhibits HDAC (20 IC50=194nM, 26 IC50=360nM) & HSP90α (20 IC50=153nM, 26 IC50=77nM), affects cancer cell survival and invasion.Formula:C20H23N3O6Color and Shape:SolidMolecular weight:401.15869YEATS4 binder-1
YEATS4 binder-1(4e) is an effective and selective compound that targets the KAc recognition site within the YEATS structural domain, exhibiting a bindingFormula:C23H34N4O3Color and Shape:SolidMolecular weight:414.54IAA65
CAS:IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].Formula:C16H13F6NO2Color and Shape:SolidMolecular weight:365.27EGFR-IN-38
CAS:EGFR-IN-38: low-toxic acrylamide-derived EGFR inhibitor, targets NSCLC, patented for research on EGFR mutation-related diseases.Formula:C25H24ClN7O2Color and Shape:SolidMolecular weight:489.96RMG8-8
RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).Formula:C41H78N8O5Color and Shape:SolidMolecular weight:763.11GPR84 antagonist 1
GPR84 antagonist 1 is a highly selective, high-affinity competitive antagonist of human GPR84.Formula:C26H22N4O2Color and Shape:SolidMolecular weight:422.48RBM10-8
CAS:RBM10-8 irreversibly inhibits human sphingosine-1- phosphate lyase (hS1PL) while behaving also as an enzyme substrate.Formula:C17H36NO5PColor and Shape:SolidMolecular weight:365.45Chitin synthase inhibitor 1
Potent, selective CHS inhibitor with 0.12 mM IC50; effective against drug-resistant fungi.Formula:C22H20ClN3O3Color and Shape:SolidMolecular weight:409.87HBV-IN-19 TFA
CAS:HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.Formula:C26H31F3N2O8Color and Shape:SolidMolecular weight:556.53Nrf2 activator-2
Compound O15, an Osthole derivative, is a potent Nrf2 agonist with an EC50 of 2.9 μM; it inhibits Keap1-Nrf2 binding and Nrf2 ubiquitination.Formula:C20H17BrO3Color and Shape:SolidMolecular weight:385.25rel-MDM2/4-p53-IN-3
rel-MDM2/4-p53-IN-3 inhibits MDM2/4-p53 PPI, IC50: MDM2 18.5nM, MDM4 14.8nM, targets cancer research.Formula:C25H24Cl2FN3O3Color and Shape:SolidMolecular weight:504.38Anticancer agent 65
CAS:Anticancer agent 65: Effective on A549 cells, IC50 1.07 μM, halts S phase, triggers apoptosis, elevates p53/p21, causes ROS and MMP collapse.Formula:C36H63NO5Color and Shape:SolidMolecular weight:589.89p38-α MAPK-IN-5
CAS:p38-α MAPK-IN-5: potent p38α inhibitor, IC50s: 0.1 nM (α), 0.2 nM (β), 944 nM (γ), 4100 nM (δ); anti-inflammatory, promising for asthma/COPD research.Formula:C37H49N11O2Color and Shape:SolidMolecular weight:679.86NF-κB-IN-6
NF-κB-IN-6 (Compound 3d) is an anti-inflammatory agent that works by reducing the protein expression of iNOS and COX-2 by suppressing the NF-κB signalingFormula:C14H20N2O3Color and Shape:SolidMolecular weight:264.32PAT-347
CAS:PAT-347 is a potent inhibitor of Autotaxin, an enzyme linked to cell survival and diseases like cancer and fibrosis.Formula:C28H21ClF2N2O3SColor and Shape:SolidMolecular weight:538.99P300 bromodomain-IN-1
P300 bromodomain-IN-1 blocks c-Myc, induces G1/G0 arrest, apoptosis. Potent EP300 inhibitor (IC50: 49 nM).Formula:C29H31ClN4O4Color and Shape:SolidMolecular weight:535.03RMS-07
CAS:RMS-07, a covalent MPS1/TTK inhibitor, has an IC50 of 13.1 nM, targeting a kinase hinge cysteine.Formula:C35H40N8O2Color and Shape:SolidMolecular weight:604.74CLR01 sodium
CAS:CLR01 is a tweezer reducing α-synuclein in MSA, inhibits SOD1 in ALS, blocks Ebola/Zika, stabilizes proteins, and lessens mutant p53 toxicity.Formula:C42H30Na2O8P2Color and Shape:SolidMolecular weight:770.6211YW3-56
CAS:YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.Formula:C27H32ClN5O2Color and Shape:SolidMolecular weight:494.03OMDM169
CAS:OMDM169: potent/selective MAGL inhibitor, raises 2-AG, analgesic via cannabinoid receptors, IC50: 0.13-0.41μM in rat/COS-7, inactive at CB1/CB2.Formula:C25H45NO5Purity:98%Color and Shape:SolidMolecular weight:439.63AM-9514
CAS:AM-9514: a potent Glucokinase activator with strong in vitro results, good pharmacokinetics, and efficacy in diabetes.Formula:C18H25N5O4Color and Shape:SolidMolecular weight:375.42LY593093
CAS:LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.Formula:C32H30FN3O2Purity:98%Color and Shape:SolidMolecular weight:507.6Exicorilant
CAS:Exicorilant is a selective oral GR antagonist (Ki: 7 nM) that may reduce obesity, glucose intolerance, & dyslipidemia.Formula:C26H23F4N7O3SPurity:98%Color and Shape:SolidMolecular weight:589.56GSK-3β inhibitor 6
GSK-3β inhibitor 6 is a highly potent inhibitor of GSK-3β, with an IC50 value of 24.4 μM.Formula:C20H17BrN4Color and Shape:SolidMolecular weight:393.28β-Glucuronidase/hCAII-IN-2
β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.Formula:C31H23NO8Color and Shape:SolidMolecular weight:537.52
