Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,832 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,611 products)
- Cytoskeletal Signaling(1,563 products)
- DNA Damage/DNA Repair(2,873 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,900 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,141 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,369 products)
- Other Inhibitors(35,851 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,429 products)
- Proteases/Proteasome(1,690 products)
- Stem Cell and Derivatives(735 products)
- Tyrosine Kinase/Adaptors(1,982 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
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Cyclic-di-GMP sodium
c-di-GMP sodium: STING activator, regulates bacteria biofilm, motility, virulence.Formula:C20H24N10NaO14P2Color and Shape:SolidMolecular weight:713.08464PF-00446687
CAS:PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM).Formula:C28H36F2N2O2Purity:98%Color and Shape:SolidMolecular weight:470.59RmlA-IN-2
RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).Formula:C22H26BrN5O4SColor and Shape:SolidMolecular weight:536.44COX-2-IN-29
COX-2-IN-29 is a selective inhibitor of orally active COX-2 (IC50: 0.005 μM).Formula:C22H23FN2O6S2Color and Shape:SolidMolecular weight:494.56VEGFR-2-IN-14
VEGFR-2-IN-14 (Compound 5) is a potent inhibitor of VEGFR-2, which inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.Formula:C24H23N3O3SColor and Shape:SolidMolecular weight:433.52RORγt inhibitor 2
CAS:RORγt Inhibitor 2, a potent inhibitor of RORγt, exhibits an IC50 of 9.2 nM and is utilized in the study of cancer, inflammation, or autoimmune diseases that areFormula:C31H33F5N2O7SColor and Shape:SolidMolecular weight:672.66THR-β agonist 5
CAS:THR-β agonist 5 (compound 54) is a potent THR-β agonist, with an EC 50 of <50 nM [1].Formula:C22H23N5O2Color and Shape:SolidMolecular weight:389.45BF-168
CAS:BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).Formula:C18H17FN2O2Color and Shape:SolidMolecular weight:312.34LXR antagonist 2
LXR antagonist 2 inhibits adipogenesis, downregulates LXR genes, and reduces lipids in hyperlipidemic mice (LXRβ IC50: 0.36μM, LXRα IC50: 2.25μM).
Formula:C34H40N2O5SColor and Shape:SolidMolecular weight:588.76Chitin synthase inhibitor 5
Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.Formula:C23H22BrN3O5Color and Shape:SolidMolecular weight:500.3412(S)-HEPE
CAS:12(S)-HEPE, made from EPA by 12-LO, is an anti-inflammatory ω-3 derivative affecting leukotriene formation.Formula:C20H30O3Color and Shape:SolidMolecular weight:318.45F 14679
CAS:F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.Formula:C21H25ClF2N4OPurity:99.09%Color and Shape:SolidMolecular weight:422.92-Methylsorbinol
CAS:2-Methylsorbinol is a bioactive chemical.Formula:C12H11FN2O3Color and Shape:SolidMolecular weight:250.23BACE1-IN-5
CAS:BACE1-IN-5 inhibits BACE1 (IC50: 9.1 nM) & Aβ production (IC50: 0.82 nM), enhances hERG inhibition & P-gp efflux.Formula:C18H16F5N5O2SPurity:98%Color and Shape:SolidMolecular weight:461.41ONO-AE1-259 lysine
CAS:ONO-AE1-259 is a highly selective agonist of prostaglandin e2 receptor (ep2)Formula:C28H49ClN2O6Color and Shape:SolidMolecular weight:545.15ODN 21158
CAS:ODN 21158 is a potent, non-cytotoxic inhibitor of G-modified TLR3 and TLR9. ODN 21158 dose-dependently inhibits IFN-α secretion.Color and Shape:SolidAZD 4407
CAS:AZD 4407 is a potent inhibitor of 5-lipoxygenase.Formula:C19H21NO3S2Purity:98%Color and Shape:SolidMolecular weight:375.5BAY-091
CAS:BAY-091 is a novel potent and highly selective PIP4K2A kinase inhibitor.Formula:C26H21FN4O2Purity:97.66% - 99.23%Color and Shape:SoildMolecular weight:440.47Ref: TM-T60147
1mg78.00€5mg168.00€10mg269.00€25mg427.00€50mg610.00€100mg820.00€500mgTo inquire1mL*10mM (DMSO)178.00€SC13
CAS:SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.Formula:C26H30N2O5Color and Shape:SolidMolecular weight:450.53MRS2279
CAS:Selective, high affinity competitive antagonist of the P2Y1 receptorFormula:C13H18ClN5O8P2Purity:98%Color and Shape:SolidMolecular weight:469.71Keap1-Nrf2-IN-5
CAS:Keap1-Nrf2-IN-5 is a potent inhibitor of Keap1-Nrf2 PPI (Keap1-Nrf2 protein-protein interaction) (IC50: 4.1 μM, Kd: 3.7 μM).Formula:C23H30N4O6SColor and Shape:SolidMolecular weight:490.57IL-17 modulator 1 disodium
CAS:Potent, orally active IL-17 Modulator 1 (disodium) from patent WO 2020127685, used in psoriasis and arthritis research.Formula:C28H37N6NaO6PColor and Shape:SolidMolecular weight:607.604Omesdafexor
CAS:Omesdafexor is an FXR agonist that can be used to study diseases caused by liver disease or metabolic inflammation.Formula:C34H43N3O3Color and Shape:SolidMolecular weight:541.72Lasonolide A
CAS:Lasonolide A, an anticancer compound from Forcepia sponge, shows nanomolar growth inhibition and unique cytotoxicity in the NCI 60-cell-line screen.Formula:C41H60O9Color and Shape:SolidMolecular weight:696.91Atiratecan
CAS:Atiratecan (TP300), a CH0793076-based camptothecin prodrug, combats BCRP+/- tumors; doesn't affect AChE.Formula:C31H34N6O6Purity:98%Color and Shape:SolidMolecular weight:586.645-HT6/5-HT2AR antagonist-1
Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM & 39 nM.Formula:C21H26N6SColor and Shape:SolidMolecular weight:394.54FXIa-6f
CAS:FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical speciesFormula:C31H29ClF2N4O4Color and Shape:SolidMolecular weight:595.04CI-988
CAS:CCK2 (CCK-B) receptor antagonistFormula:C35H42N4O6Purity:98%Color and Shape:SolidMolecular weight:614.73R-96544 hydrochloride
CAS:5-HT2 receptor antagonistFormula:C22H29NO3Purity:98%Color and Shape:SolidMolecular weight:355.47S-HP210
S-HP210: selective GR modulator, blocks NF-κB (IC50: 1.92 μM), non-toxic to mouse fibroblasts.Formula:C22H19N3O2S2Color and Shape:SolidMolecular weight:421.54Mevidalen HBA
CAS:Mevidalen (LY3154207), a potent D1 positive allosteric modulator, is in clinical trials for Lewy body dementia.Formula:C31H35Cl2NO6Color and Shape:SolidMolecular weight:588.52CHK-IN-1
CAS:CHK-IN-1 is a dual inhibitor of CHK1 and CHK2 with antiproliferative activity.Formula:C18H19ClFN5OSPurity:>99.99%Color and Shape:SolidMolecular weight:407.89Anticancer agent 35
Compound 10, a sulfonylurea, inhibits A549, A431, PACA2 cells with IC50s: 18.1, 4.0, 18.9 μg/mL.Formula:C15H13N3O3S3Color and Shape:SolidMolecular weight:379.48NSC381467
CAS:NSC381467: Potent, oral EGFR-TK inhibitor with strong antiproliferative effects, promising for cancer research.Formula:C20H16O7Color and Shape:SolidMolecular weight:368.34Chitin synthase inhibitor 1
Potent, selective CHS inhibitor with 0.12 mM IC50; effective against drug-resistant fungi.Formula:C22H20ClN3O3Color and Shape:SolidMolecular weight:409.87GSK-1264
CAS:GSK-1264: allosteric HIV integrase inhibitor, halts viral replication & abnormal protein multimerization.Formula:C26H28FNO5Color and Shape:SolidMolecular weight:453.5BTK-IN-6
BTK-IN-6, a potent BTK inhibitor, may treat immune, cardiac, cancer, viral, inflammatory, metabolic, and neurological disorders.Formula:C23H22FN5O3Color and Shape:SolidMolecular weight:435.45ZLM-66
ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.Color and Shape:SolidStreptonigrin (racemate)
CAS:Streptonigrin: aminoquinone antibiotic; antitumor, antibacterial; blocks β-Catenin/Tcf, cytotoxic; alters hamster chromosomes; (-)-isomer, CAS#3930-19-6.Formula:C25H22N4O8Color and Shape:SolidMolecular weight:506.46Plumbemycin B
CAS:Plumbemycin B is isolated from Streptomyces plumbeus; an L-threonine antagonist.Formula:C12H21N4O8PColor and Shape:SolidMolecular weight:380.29NTPDase-IN-2
CAS:NTPDase-IN-2 inhibits h-NTPDase-2/-8 (IC50: 0.04, 2.27 µM), non-competitive for h-NTPDase-1/-2 (Km: 74 µM); useful in cancer, immune, bacterial research.Formula:C24H20FN3OS2Color and Shape:SolidMolecular weight:449.56Aspochalasin M
CAS:Aspochalasin M shows moderate activity on HL-60 cells (IC50=20.0 μ M). Aspochalasin M has research potential in leukemia diseases.Formula:C24H35NO4Color and Shape:SolidMolecular weight:401.54OSI-7904L free acid
CAS:OSI-7904L is a folate-based thymidylate synthase inhibitor. It also has antimalarial and antitumor properties.Formula:C27H24N4O6Purity:98%Color and Shape:SolidMolecular weight:500.5GSK3527497
CAS:GSK3527497 is a novel potent and selective inhibitor of transient receptor potential vanilloid-4 (TRPV4).Formula:C17H16ClFN4O4SColor and Shape:SolidMolecular weight:426.85Freselestat
CAS:Freselestat (ONO-6818) inhibits neutrophil elastase, reduces interleukin 8, C5B-9, and inflammation in cardiopulmonary bypass.Formula:C23H28N6O4Color and Shape:SolidMolecular weight:452.51FTI-2148
CAS:FTI-2148 blocks RAS-related FT-1 & GGT-1; IC50: 1.4 nM & 1.7 μM.Formula:C24H28N4O3SPurity:98%Color and Shape:SolidMolecular weight:452.57Iroxanadine hydrobromide
CAS:Iroxanadine hydrobromide is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.Formula:C14H21BrN4OColor and Shape:SolidMolecular weight:341.25Pamiparib maleate
CAS:Pamiparib (BGB-290) is a selective PARP inhibitor that blocks DNA repair and promotes apoptosis.Formula:C44H42F2N8O14Purity:98%Color and Shape:SolidMolecular weight:944.859Calphostin B
CAS:Calphostins, PKC inhibitors from Cladosporium fungus, include A, B, C, D, I; C is most potent.Formula:C37H34O11Color and Shape:SolidMolecular weight:654.66MtDTBS-IN-1
MtDTBS-IN-1 is a notably potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.Formula:C16H16N4O5Color and Shape:SolidMolecular weight:344.32
