Inhibitors
Inhibitors are molecules that bind to enzymes, receptors, or other proteins to reduce or block their biological activity. These compounds are widely used in research to study biological pathways, understand disease mechanisms, and develop therapeutic drugs. Inhibitors play a crucial role in the treatment of various diseases, including cancer, cardiovascular diseases, and infections. At CymitQuimica, we provide a diverse range of high-quality inhibitors to support your research in biochemistry, cell biology, and pharmaceutical development.
Subcategories of "Inhibitors"
- Angiogenesis(2,832 products)
- Apoptosis(6,315 products)
- Cell Cycle/Checkpoint(4,875 products)
- Chromatin/Epigenetics(2,611 products)
- Cytoskeletal Signaling(1,563 products)
- DNA Damage/DNA Repair(2,873 products)
- Endocrinology/Hormones(3,754 products)
- Enzyme(3,672 products)
- GPCR/G-Protein(9,014 products)
- Immunology and Inflammation(3,900 products)
- Influenza Virus(300 products)
- JAK/STAT signaling(415 products)
- MAPK Signaling(1,256 products)
- Membrane Transporter/Ion Channel(3,154 products)
- Metabolism(10,141 products)
- Microbiology/Virology(7,620 products)
- Neuroscience(10,369 products)
- Other Inhibitors(35,851 products)
- Oxidation-Reduction(40 products)
- PI3K/Akt/mTOR Signaling(1,429 products)
- Proteases/Proteasome(1,690 products)
- Stem Cell and Derivatives(735 products)
- Tyrosine Kinase/Adaptors(1,982 products)
- Ubiquitination(1,726 products)
Show 16 more subcategories
Found 66522 products of "Inhibitors"
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Tubulin polymerization-IN-6
Compound 5f, a potent tubulin polymerization inhibitor (IC50 = 1.09 μM), blocks cell migration, tube formation, and has anti-angiogenic effects.Formula:C19H21NO7Color and Shape:SolidMolecular weight:375.37EGFR/HER2/DHFR-IN-1
Potent EGFR/HER2/DHFR inhibitor for MCF-7 breast cancer; IC50: 0.153/0.108/0.291 μM; arrests G1/S phase, triggers apoptosis.Formula:C14H11BrN4O2SColor and Shape:SolidMolecular weight:379.23Ambuic acid
CAS:Ambuic acid: cyclohexanone with antifungal, quorum-inhibiting, antibacterial properties, blocks cyclic peptides; reduces MRSA abscesses in mice.Formula:C19H26O6Color and Shape:SolidMolecular weight:350.41LLS30
CAS:LLS30 inhibits Gal-1, reduces its binding affinity, and may help treat advanced prostate cancer.Formula:C34H33Cl4N5O3Color and Shape:SolidMolecular weight:701.47HDAC-IN-35
HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.Formula:C17H13ClF3N3O3Color and Shape:SolidMolecular weight:399.75Mibefradil
CAS:Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).Formula:C29H38FN3O3Purity:98%Color and Shape:SolidMolecular weight:495.63PF-5177624
CAS:PF-5177624 is a selective and potent PDK1 inhibitor inducing anti-tumor activity in breast cancer cells.Formula:C25H25FN8O2Color and Shape:SolidMolecular weight:488.52TRK-IN-12
CAS:TRK-IN-12 (9e), a macrocyclic TRK inhibitor (G595R IC50=13.1 nM), outperforms LOXO-101 in Ba/F3-NTRK1 cells.Formula:C18H19ClFN5O3SColor and Shape:SolidMolecular weight:439.89SCH-1473759
CAS:SCH-1473759 is an inhibitor of the aurora (IC50s: 4 and 13 nM for Aurora A and B, respectively).Formula:C20H26N8OSPurity:98%Color and Shape:SolidMolecular weight:426.54AFP-07
CAS:AFP-07 is a highly selective and potent agonist. It was used for the prostacyclin receptor.Formula:C22H29F2NaO5Purity:98%Color and Shape:SolidMolecular weight:434.45SARS-CoV-2 nsp3-IN-1
Compound 15c selectively inhibits SARS-CoV-2 nsp3 Mac1 with IC50 of 6.1 μM.Formula:C17H15N5O2Color and Shape:SolidMolecular weight:321.33Acetomycin
CAS:Acetomycin, a γ-lactone from S. ramulosus, halts HCT-8 colon and L1210 leukemia cell growth.Formula:C10H14O5Color and Shape:SolidMolecular weight:214.22BM635 mesylate
BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.Formula:C26H33FN2O4SColor and Shape:SolidMolecular weight:488.61(Rac)-PT2399
CAS:(Rac)-PT2399 is a potent and specific inhibitor of hypoxia-inducible factor 2a (HIF-2α)(IC50 of 0.01 μM).Formula:C17H10F5NO4SColor and Shape:SolidMolecular weight:419.32IRL 2500
CAS:IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.Formula:C36H35N3O4Purity:99.36%Color and Shape:White Crystalline SolidMolecular weight:573.68L-739750
CAS:L-739,750 is an inhibitor (FTI) of peptidomimetic farnesyltransferase.Formula:C23H39N3O6S2Purity:98%Color and Shape:SolidMolecular weight:517.7DG013A
CAS:DG013A inhibits ERAP1 & ERAP2 (IC50: 33 nM & 11 nM) to research autoimmune diseases & cancer.Formula:C27H37N4O4PColor and Shape:SolidMolecular weight:512.58Topo I/COX-2-IN-2
Compound W10 is a dual inhibitor of Topo I (IC50: 0.90μM) and COX-2 (IC50: 2.31μM), inducing cancer cell apoptosis via mitochondria.Formula:C24H25ClN4OColor and Shape:SolidMolecular weight:420.93iNOS/PGE2-IN-1
iNOS/PGE2-IN-1: iNOS/PGE2 inhibitor, reduces LPS-induced NO, low ulcer risk, anti-inflammatory.Formula:C26H22ClN3O4Color and Shape:SolidMolecular weight:475.92VDR agonist 1
CAS:Compound 28 is a nonsteroidal VDR agonist with 690 nM potency, inducing cell cycle arrest and apoptosis in MCF-7 cells.Formula:C32H51N3O2Purity:98%Color and Shape:SolidMolecular weight:509.77ABT-072
CAS:ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.Formula:C24H27N3O5SPurity:98%Color and Shape:SolidMolecular weight:469.55Oberadilol
CAS:Oberadilol is a pyridazinone derivative with vasodilatory and beta-adrenergic blocking activities and type III phosphodiesterase inhibitory actionFormula:C25H30ClN5O3Color and Shape:SolidMolecular weight:483.99GNTI TFA
CAS:GNTI TFA is a selective kappa opioid receptor antagonist.Formula:C31H31F6N5O7Color and Shape:SolidMolecular weight:699.60LY 215890
CAS:LY 215890 is a compound that exhibits potent Gram-negative and Gram-positive antibacterial activity.Formula:C13H12ClN5O5SPurity:98%Color and Shape:SolidMolecular weight:385.78IDO1-IN-14
IDO1-IN-14 is an IDO1 enzyme inhibitor with an IC50 of 396.9 nM and suppresses HeLa cell activity with an EC50 of 3393 nM.Formula:C18H12Cl2FN3O2Color and Shape:SolidMolecular weight:392.21Danshenxinkun D
CAS:Danshenxinkun D has antituberculosis H_(37)Rv activity in vitro.Formula:C21H20O4Purity:98%Color and Shape:SolidMolecular weight:336.38G108
CAS:G108 is an inhibitor of human cGAS and is used in the study of autoimmune diseases associated with human cGAS.Formula:C16H14Cl2N4O2Purity:99.13% - 99.75%Color and Shape:SolidMolecular weight:365.21Carbacyclin
CAS:Carbacyclin, a PGI2 analog, is a prostacyclin (PGI2) receptor agonist and vasodilator with potent inhibitory platelet aggregation.Formula:C21H34O4Purity:98%Color and Shape:SolidMolecular weight:350.49MS8815
CAS:MS8815 is a selective EZH2 PROTAC degrader with IC50 of 8.6 nM, used in triple-negative breast cancer research.Formula:C65H87N9O8SColor and Shape:SolidMolecular weight:1154.51Befiradol hydrochloride
CAS:Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.Formula:C20H23Cl2F2N3OPurity:99.64%Color and Shape:SolidMolecular weight:430.32EED ligand 1
EED ligand 1: potent PRC2 inhibitor targeting EED subunit.Formula:C19H19FN8OColor and Shape:SolidMolecular weight:394.41Burapitant
CAS:Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.
Formula:C31H35Cl2F6N3O3Purity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:682.52L 739749
CAS:L 739749 is a CAAX peptidomimetic. It is also an inhibitor of farnesyl-protein transferase.Formula:C24H41N3O6S2Purity:98%Color and Shape:SolidMolecular weight:531.73Foroxymithine
CAS:Foroxymithine is an inhibitor of angiotensin-converting enzyme.Formula:C22H37N7O11Purity:98%Color and Shape:SolidMolecular weight:575.57Oiligodendrocyte differentiation promoter 1
CAS:Oiligodendrocyte differentiation promoter 1 is a promoter of oiligodendrocyte differentiation .Formula:C25H25Cl2NO5Purity:98%Color and Shape:SolidMolecular weight:490.38Taprostene
CAS:Taprostene (CG-4203), a stable Prostacyclin analogue, protects endothelium and myocardium post-ischemia in cats, with minimal hemodynamic impact.Formula:C24H30O5Color and Shape:SolidMolecular weight:398.49MtTMPK-IN-3
CAS:MtTMPK-IN-3 inhibits Mycobacterium tuberculosis kinase with IC50 0.12μM, MIC 12.5μM on Mtb, cytotoxic EC50 12.5μM on MRC-5 cells.Formula:C23H23Cl2N3O3Color and Shape:SolidMolecular weight:460.35PDHK-IN-4
PDHK-IN-4 inhibits PDHK2 (IC50: 0.0051 μM) & PDHK4 (IC50: 0.0122 μM), with potential for cancer research.Formula:C24H25N5O3Color and Shape:SolidMolecular weight:431.49AKT-IN-10
CAS:AKT-IN-10, a potent AKT inhibitor, has potential for breast and prostate cancer research, impacting cell growth and survival pathways.Formula:C26H34ClN5O2Color and Shape:SolidMolecular weight:484.03PARP1-IN-5
PARP1-IN-5 is a potent, selective, orally active, low-toxicity PARP-1 inhibitor with an IC50 value of 14.7 nM. PARP1-IN-5 can be used in cancer research.Formula:C25H24N2O5SColor and Shape:SolidMolecular weight:464.53OM-153
CAS:OM-153 blocks tankyrase 1 (IC50: 13 nM) and 2 (IC50: 2 nM), stifling WNT signaling and COLO 320DM cell growth.Formula:C28H24FN7O2Color and Shape:SolidMolecular weight:509.53Fipravirimat
CAS:Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.Formula:C43H67FN2O4SColor and Shape:SolidMolecular weight:727.07PTP1B-IN-21
PTP1B-IN-21 inhibits PTP1B (IC50=1.56μM) selectively over TCPTP, a type 2 diabetes target.Formula:C22H22O11Color and Shape:SolidMolecular weight:462.4PqsR-IN-1
PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.Formula:C17H18ClN3OSColor and Shape:SolidMolecular weight:347.86Cap-dependent endonuclease-IN-14
CAS:Cap-dependent endonuclease-IN-14 hinders CEN and could treat influenza virus infections. (Patent CN113620948A, compound 1-c).Formula:C30H23FN2O6SColor and Shape:SolidMolecular weight:558.58β-N-Acetyl-D-hexosaminidase-IN-1
β-N-Acetyl-D-hexosaminidase-IN-1 is a newly discovered chemical compound that acts as an inhibitor for β-N-acetyl-D-hexosaminidase.Formula:C18H13F2NO2SColor and Shape:SolidMolecular weight:345.36BRD-K25923209
CAS:BRD-K25923209 is a novel inhibitor of BAF transcriptional repression.Formula:C29H36N4O3Color and Shape:SolidMolecular weight:488.62MSK-195
CAS:MSK-195 is an effective TRPV1 agonist.Formula:C28H40N2O5Purity:98%Color and Shape:SolidMolecular weight:484.63MrgprX2 antagonist-6
MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation.Formula:C24H23F3N6O3Color and Shape:SolidMolecular weight:500.47rel-MDM2/4-p53-IN-2
Potent dual MDM2/MDM4 inhibitor & p53 activator; IC50: 70.7 nM (MDM2), 81.4 nM (MDM4); regulates cell cycle, triggers apoptosis, anti-cancer.Formula:C25H17Cl3FN3O3Color and Shape:SolidMolecular weight:532.78
