
Purines and Pyrimidine Derivatives
Purines have a bicyclic structure, consisting of a six-membered ring fused to a five-membered ring, both containing nitrogen atoms in key positions. Purine derivatives, such as adenine and guanine, are essential for the formation of DNA and RNA. These compounds have therapeutic applications in cancer and viral disease treatments by inhibiting cell replication. Pyrimidines, on the other hand, have a monocyclic six-membered structure with two nitrogen atoms. Their derivatives, such as cytosine, thymine, and uracil, are also essential components of DNA and RNA and are used in chemotherapy and antiviral treatments.
At CymitQuimica, we offer purine and pyrimidine derivatives for research in molecular biology, genomics, and the development of innovative therapies.
Found 8901 products of "Purines and Pyrimidine Derivatives"
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(R)- 3-[(1-Methyl-2-pyrrolidinyl)methyl]-1H-Indole
CAS:Controlled ProductFormula:C14H18N2Color and Shape:NeatMolecular weight:214.31Valbenazine (~90% Purity)
CAS:Controlled Product<p>Applications Valbenzine is a highly selective vesicular monoamine transporter 2 inhibitor. It is used in the treatment of tardive dykinesia.<br>References O'Brien, C. et al.: Movement Dis., 30, 1681 (2015);<br></p>Formula:C24H38N2O4Purity:~90%Color and Shape:NeatMolecular weight:418.57Ethyl 2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate
Controlled Product<p>Applications Ethyl 2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate, is an impurity in the synthesis of Febuxostat n-Butyl Isomer (F229035).<br></p>Formula:C18H20N2O3SColor and Shape:NeatMolecular weight:344.43Febuxostat Acyl-β-D-glucuronide
CAS:<p>Applications A metabolite of Febuxostat (F229000), a novel nonpurine selective inhibitor of Xanthin Oxidase.<br>References Grabowski, B., et al.: J. Clin. Pharmacol., 51, 189 (2011); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formula:C22H24N2O9SColor and Shape:Off White PowderMolecular weight:492.502-Oxo Clopidogrel-13C,d3 Hydrochloride(Mixture of Diastereomers)
CAS:Controlled ProductFormula:C1513CH14D3Cl2NO3SColor and Shape:NeatMolecular weight:378.29m-Hydroxyhippuric Acid-13C2, 15N
CAS:<p>Applications m-Hydroxyhippuric Acid-13C2, 15N is labelled m-Hydroxyhippuric Acid (H943125) which is a metabolite of caffeic and chlorogenic acids in human.<br>References Booth, A., et al.: J. Biol. Chem., 229, 51 (1957); Gonthier, M., et al.: Biomed. Pharmacother., 60, 536 (2006)<br></p>Formula:C713C2H915NO4Color and Shape:White To Off-WhiteMolecular weight:198.15N10-Monodesmethyl Rizatriptan
CAS:Controlled Product<p>Impurity Rizatriptan EP Impurity I<br>Applications N10-Monodesmethyl Rizatriptan (Rizatriptan EP Impurity I) is a metabolite of Rizatriptan.<br>References Dechant, K., et al.: Drugs, 43, 776 (1992), Castro, J., et al.: Bioorg. Med. Chem. Lett., 3, 993 (1993), Lee, Y., et al.: Biopharm. Drug Dispos., 19, 577 (1998), Chen, J., et al.: J. Pharm. Biomed. Anal., 35, 639 (2004),<br></p>Formula:C14H17N5Color and Shape:NeatMolecular weight:255.32Methotrexate Tetraglutamate Trifluoroacetate
CAS:Controlled Product<p>Applications Methotrexate Tetraglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formula:C35H43N11O14xC2HF3O2Color and Shape:NeatMolecular weight:841.78N-(5-Aminopentyl) Methotrexate Amide
CAS:Controlled Product<p>Applications The 5-aminopentyl amide derivative of the folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.<br>References Fan, J. et al.: J. Biol. Chem., 266, 14862 (1991);<br></p>Formula:C25H34N10O4Color and Shape:NeatMolecular weight:538.6Regadenoson-d3
CAS:Controlled Product<p>Applications A selective A2A adenosine receptor agonist in myocardial imaging.<br>References Palle, V.P., et al.: J. A. Drug Dev. Res., 50, 64 (2000), Gordi, T., et al.: J. Clin. Pharmacol., 47, 825 (2007), Zhao, G., et al.: J. Cardiovas. Pharmacol., 52, 467 (2008), Botvinick, E., et al.: J. Nuc. Med. Technol., 37, 14 (2009),<br></p>Formula:C15H15D3N8O5Color and Shape:NeatMolecular weight:393.376-Oxo-(S,S)-Palonosetron (~90%)
CAS:Controlled Product<p>Applications 6-Oxo-(S,S)-Palonosetron is an impurity of (S,S)-Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.<br>References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),<br></p>Formula:C19H22N2O2Purity:~90%Color and Shape:NeatMolecular weight:310.39Tenofovir (1 mg/mL in Water)
CAS:Formula:C9H14N5O4PColor and Shape:Single SolutionMolecular weight:287.21Hydroxy Urea-15N
CAS:Controlled Product<p>Applications Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>Formula:CH415NNO2Color and Shape:NeatMolecular weight:77.054-Hydroxy-1,3-benzenedicarbonitrile
CAS:Controlled Product<p>Applications 4-Hydroxy-1,3-benzenedicarbonitrile is used in the preparation of febuxostat (F229000), a non-purine xanthine oxidase inhibitor used as a treatment for hyperuricaemia and chronic gout.<br>References Smith, C.J., et al.: Bioorg. Med. Chem. Lett., 20, 346 (2010); Cramp. S., et al.: BIoorg. Med. Chem. Lett., 20, 2516 (2010); Sato, T., et al.: Bioorg. Med. Chem. Lett., 19, 184 (2009);<br></p>Formula:C8H4N2OColor and Shape:NeatMolecular weight:144.132-Chloro-6-amino-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine
CAS:Controlled Product<p>Applications 2-Chloro-6-amino-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (cas# 79999-39-6) is a compound useful in organic synthesis.<br></p>Formula:C16H18ClN5O7Color and Shape:NeatMolecular weight:427.80Lestaurtinib
CAS:Controlled Product<p>Stability Photosensitive<br>Applications It is used for the treatment of pancreatic cancer and acute myelogenous leukaemia (AML).<br></p>Formula:C26H21N3O4Color and Shape:NeatMolecular weight:439.46Diethylaminocarboxymethyl POC Tenofovir (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral. Tenofovir (T018500) impurity.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Formula:C20H33N6O9PColor and Shape:NeatMolecular weight:532.481-Bromoethyl Acetate (~90%)
CAS:Controlled Product<p>Applications 1-Bromoethyl Acetate is a 1-haloalkyl ester that is used in the modification of antibiotics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zakrzewski, J. et al.: Pol. J. Chem. Technol., 8, 83 (2006); Kamachi, H. et al.: J. Antibiot., 41, 1602 (1988);<br></p>Formula:C4H7BrO2Purity:~90%Color and Shape:NeatMolecular weight:167.0Chloroformic Acid Chloromethyl Ester
CAS:Controlled Product<p>Stability Very Very Moisture sensitive<br>Applications Chloroformic Acid Chloromethyl Ester is used as a reagent in the synthesis of carbamates and carbonates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Safadi, M. et al.: Pharm. Res. 10, 1350 (1993); Loren, J.C. et al.: Synlett, 18, 2847 (2005);<br></p>Formula:C2H2Cl2O2Color and Shape:Colourless OilyMolecular weight:128.94Caffeine Citrate
CAS:<p>Applications Caffeine citrate (Cafcit) is a citrate salt of Caffeine, sometimes used in medical treatment, including short-term treatment of apnea of prematurity (lack of breathing in premature infants). Caffeine citrate functions in much the same capacity as does caffeine, but takes effect more quickly; its speed of dissociation is faster than that of Caffeine. Caffeine citrate is typically only used to treat severe migraines.<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988); Grillon, C., et al.: Clin. Neurophysiol., 114, 1557 (2003); Duangdao, D., et al.: Behav. Brain Res., 205, 1 (2009);<br></p>Formula:C8H10N4O2·C6H8O7Color and Shape:WhiteMolecular weight:386.31Methotrexate Hexaglutamate Trifluoroacetate
CAS:<p>Stability Hygroscopic<br>Applications Methotrexate Hexaglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formula:C45H57N13O20·x(C2HF3O2)Color and Shape:Yellow SolidMolecular weight:1214.035-[1-(2-Chlorophenyl)-2-methoxy-2-oxoethyl]-6,7-dihydrothieno[3,2-c]pyridiniumBromide (~90%)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications One of the unknown impurities generated during the accelerated stability storage of Clopidogrel bisulfate tablets. Clopidogrel impurity.<br>References Gomez, Y., et al.: J. Pharm. Biomed. Anal., 34, 341 (2004), Ksycinska, H., et al.: J. Pharm. Biomed. Anal., 41, 533 (2006),<br></p>Formula:C16H15ClNO2S·BrPurity:~90%Color and Shape:NeatMolecular weight:400.72N-Sulfamoylethyl Naratriptan Pyridinium Chloride
CAS:Controlled Product<p>Impurity Naratriptan Impurity F<br>Stability Hygroscopic<br>Applications 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium Chloride is an impurity of Naratriptan (N378730).<br></p>Formula:C20H27ClN4O4S2Color and Shape:NeatMolecular weight:487.04p-Chlorophenylcyanoguanidine
CAS:Controlled Product<p>Impurity Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine)<br>Applications Halo-aryl substituted guanidine derivative used in the preparation of antimalarial agents. Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine).<br>References Warner, V. et al.: J. Pharmac. Sci., 66, 418 (1977); Das, A. et al.: Ind. Drugs, 20, 19 (1980);<br></p>Formula:C8H7ClN4Color and Shape:NeatMolecular weight:194.62Diethyl p-Toluenesulfonyloxymethylphosphonate
CAS:Controlled Product<p>Applications Diethyl p-Toluenesulfonyloxymethylphosphonate is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C12H19O6PSColor and Shape:NeatMolecular weight:322.31Pemetrexed Disodium Heptahydrate
CAS:Controlled Product<p>Applications Pemetrexed Disodium Heptahydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.<br>References Vogelzang, N.J., et al.: J. Clin. Oncol., 21,2636 (2003); Paz-Ares, L., et al.: Lancet. Oncol., 13, 247 (2012);<br></p>Formula:C20H19N5O6·2Na·7H2OColor and Shape:NeatMolecular weight:597.48Glycylglycyl-L-tyrosine
CAS:<p>Applications Fungal tyrosinases and their capability to oxidize peptide-bound tyrosine residues is important in a view of applicability of tyrosinases.<br>References Bowness, J., et al.: Biochem. J., 53, 620 (1953), Cuff, M., et al.: J. Mol. Biol., 278, 855 (1998), Kubo, I., et al.: Bioorg. Med. Chem., 12, 5349 (2004),<br></p>Formula:C13H17N3O5Color and Shape:NeatMolecular weight:295.2912Tetrabenazine
CAS:Controlled Product<p>Applications Dopamine depleting agent. An antidyskinetic; antipsychotic.<br>References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),<br></p>Formula:C19H27NO3Color and Shape:NeatMolecular weight:317.42Oseltamivir Acid Methyl Ester Phosphate Salt
CAS:<p>Applications An impurity of the antiviral drug Oseltamivir (O700100). It is a COVID19-related research product.<br></p>Formula:C15H29N2O8PColor and Shape:NeatMolecular weight:396.372,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Methotrexate intermediate.<br>References Feng, Y., et al.: J. Med. Chem., 49, 770 (2006),<br></p>Formula:C7H8N6O·ClHColor and Shape:YellowMolecular weight:228.64Almotriptan-d6 Hydrochloride
CAS:Controlled Product<p>Applications: Labelled Almotriptan (A575200). Almotriptan is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraine.<br>References Fleishaker, J.C., et al.: Clin. Pharmacol. Ther., 67, 498 (2000), Kamali, F., et al.: Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs, 2, 197 (2000), Dodick, D.W., et al.: Expert Opin.Pharmacother., 4, 1157 (2003)<br></p>Formula:C172H6H19N3O2S·ClHColor and Shape:NeatMolecular weight:377.96Caffeidine Acid
CAS:Controlled Product<p>Applications Caffeidine Acid is a degradation compound of Caffeine (C080100), which is a central nervous system stimulant.<br>References Kigasawa, K., et al.: Chem. Pharm. Bull., 22, 2448 (1974); Peinhardt, G.: Pharmazie, 46, 812 (1991); Kumar, R., et al.: Carcinogenesis, 13, 2179 (1992);<br></p>Formula:C8H12N4O3Color and Shape:NeatMolecular weight:212.21rac-Clopidogrel Hydrogen Sulfate
CAS:Controlled Product<p>Applications rac-Clopidogrel Hydrogen Sulfate is used in the synthesis of Clopidogrel derivatives as platelet aggregation inhibitors.<br>References Chen, J., et. al.: Hecheng Huaxue, 18, 586 (2010); Defreyn, G. et al.: Thromb. Haemo., 65, 186 (1991);<br></p>Formula:C16H16ClNO2S·H2O4SColor and Shape:Off-WhiteMolecular weight:419.90Febuxostat 67M-2
CAS:Controlled Product<p>Applications Febuxostat 67M-2 is a derivative compound of Febuxostat 67M-1 (F229005) which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and also used to reduce the risk of gout or kidney stone formation.<br>References Du, J., et al.: Handbook of Metabolic Pathways of Xenobiotics, 4, 1395 (2014)<br></p>Formula:C16H16N2O4SColor and Shape:NeatMolecular weight:332.37Pemetrexed L-Glutamic Acid Trisodium Salt (~90%)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Pemetrexed L-Glutamic acid is an impurity of Pemetrexed (P219500). Pemetrexed impurity D.<br></p>Formula:C25H25N6O9·3NaPurity:~90%Color and Shape:NeatMolecular weight:622.47Descarboxyl Febuxostat
CAS:Controlled ProductFormula:C15H16N2OSColor and Shape:NeatMolecular weight:272.37Methotrexate-d3 (Technical Grade) (100ug/mL in Methanol with 1% 0.1N NaOH)
CAS:Controlled ProductFormula:C20H19D3N8O5Color and Shape:Single SolutionMolecular weight:457.468-13C-Uric Acid (contains ~1.5% unlabelled)
CAS:Controlled Product<p>Applications 8-13C-Uric Acid is the labeled analogue of Uric Acid (U829200), a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of Uric Acid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uric acid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant.<br>References Heinig, M. et al.: Cle. Clin. J. Med., 73, 1059 (2006); Glantzounis, G.K. et al.: Curr. Pharmac. Des., 11, 4145 (2005); Dehghan, A. et al.: Diab. Care, 31, 361 (2008); Nakagawa, T. et al.: Am. J. Physiol. Renal Physiol., 290, F625 (2006)<br></p>Formula:C413CH4N4O3Color and Shape:NeatMolecular weight:169.1(1R,5R,6R)-5-(1-Ethylpropoxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic Acid Ethyl Ester
CAS:Controlled Product<p>Applications This compound is an isomer of compound (E925685) used in the synthesis of neuraminidase inhibitors.<br>References Jarinrat K. et al.: Bioorg. Med. Chem. Lett., 20, 2152 (2012);<br></p>Formula:C14H22O4Color and Shape:NeatMolecular weight:254.32Allopurinol impurity E
CAS:<p>This product is a synthetic impurity of Allopurinol. It is a cyclization reaction product of dimethylhydrazine and allopurinol in the presence of an organic solvent such as DMF.</p>Formula:C7H9N3O3Purity:Min. 95%Molecular weight:183.16 g/molAllopurinol Sodium
CAS:<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Formula:C5H4N4NaOPurity:99.93%Color and Shape:SolidMolecular weight:159.15-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP
CAS:<p>5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is an impurity found in the synthetic process of iopamidol. It is a nonionic chemical that has been shown to be synthesized using the following methods: dichloride and synthetic. 5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is used as a contrast agent for magnetic resonance imaging (MRI).</p>Formula:C14H18I3N3O6Purity:Min. 95%Molecular weight:705.02 g/molClopidogrel Impurity A
CAS:<p>Clopidogrel Impurity A is a medicine that is used for the prevention of heart attacks, strokes, and blood clots in people with an increased risk of these events. It is not intended to be used for immediate relief from sudden symptoms. Clopidogrel Impurity A is a substance that may be found in some preparations of clopidogrel. The presence of this substance can be detected by liquid chromatography-mass spectrometry (LC-MS/MS) methods. The structural analysis of this substance was determined using enantiomeric resolution and chromatographic methods. This impurity has been shown to have no effect on the bioavailability of the parent drug, clopidogrel, when given orally to Sprague-Dawley rats.</p>Formula:C15H15Cl2NO2SPurity:Min. 95%Molecular weight:344.26 g/molMethotrexate-5-monomethyl ester
CAS:<p>Methotrexate-5-monomethyl ester is an analytical standard that is synthesized synthetically. The synthetic route used to produce the compound has been optimized for high purity, making this product suitable for use as a drug product or impurity standard. The structure of methotrexate-5-monomethyl ester was confirmed by 1H and 13C NMR spectroscopy and mass spectrometry. Methotrexate-5-monomethyl ester is an impurity found in the synthesis of methotrexate and is a metabolite of methotrexate. It has been shown to inhibit DNA synthesis and protein synthesis in animal cells, which may be due to its ability to inhibit transcription factors such as NFATc1, NFkB, STAT3, STAT5A and STAT5B.</p>Formula:C21H24N8O5Purity:Min. 95%Molecular weight:468.47 g/mol(S)-Tenofovir
CAS:<p>(S)-Tenofovir ((S)-PMPA) is the less active S-enantiomer of Tenofovir which is a nucleotide reverse transcriptase inhibitor.</p>Formula:C9H14N5O4PPurity:99.9%Color and Shape:SolidMolecular weight:287.213,4-Dihydro naratriptan
CAS:<p>3,4-Dihydro naratriptan is a medicinal compound that is used as an anti-migraine drug. It is a hydrogenated form of the parent molecule naratriptan and has been shown to have a reaction time of about 30 minutes when catalyzed by palladium. The impurity, 3,4-dihydro naratriptan sulfonamide, has been found to be less potent than the target compound and can be eliminated from the synthesis by using catalytic hydrogenation. 3,4-Dihydro naratriptan sulfonamide can also be reduced by catalytic hydrogenation to yield 3,4-dihydro naratriptan.</p>Formula:C17H23N3O2SPurity:Min. 95%Molecular weight:333.45 g/molMeropenem EP Impurity A
<p>Meropenem EP Impurity A is a synthetic, high purity, drug product that is used as an impurity standard for Meropenem. It has been synthesized from a custom synthesis and is available in both natural and synthetic form. This impurity can be used to investigate the metabolism of Meropenem and to determine its stability in different environments. The HPLC analysis of this impurity is available as a pharmacopoeia standard.</p>Formula:C17H27N3O6SPurity:Min. 95%Molecular weight:401.48 g/mol1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol
CAS:<p>1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol is a compound that contains impurities such as fatty acids and uridine. It has been found to be an inhibitor of α-mangostin adduct formation with fatty acids. Additionally, it has been shown to inhibit the activity of GSK-3β, an enzyme involved in various cellular processes. This compound also exhibits inhibitory effects on monascus and safranal, two enzymes involved in the production of certain compounds. Furthermore, it has been found to inhibit calpain, an enzyme responsible for protein degradation. The compound can be used in various research applications involving electrode modification and polylysine immobilization. It may also have potential interactions with other drugs such as cefdinir.</p>Formula:C8H9NO2Purity:Min. 95%Molecular weight:151.16 g/molZolmitriptan related compound D
CAS:<p>Zolmitriptan related compound D is a drug product that is an analytical impurity of the active ingredient, zolmitriptan. It is a synthetic compound and has been shown to be metabolized in vivo in humans. The chemical name for Zolmitriptan related compound D is 3-acetyl-5-(4-methoxyphenyl)-1H-indole-2,3-dione. This compound has been shown to have niche pharmacological properties that are not shared with other compounds in the same class, such as zolmitriptan.</p>Formula:C19H25N3O4Purity:Min. 95%Molecular weight:359.42 g/molMercaptopurine impurity standard
CAS:<p>Mercaptopurine impurity standard is a drug product that is used as an analytical reference standard in the development of drugs. Mercaptopurine impurity standard is a natural metabolite of 6-mercaptopurine, which is used to treat leukemia and other forms of cancer. It has been shown to have an anti-inflammatory effect, but this has not been confirmed. Mercaptopurine impurity standard is a synthetic compound that is made synthetically for use as an impurity standard. It has also been shown to be metabolized by cytochrome P450 enzymes, glutathione reductase, or conjugation with glucuronic acid. Mercaptopurine impurity standard has been shown to be stable under acidic conditions and heat treatment at temperatures up to 200°C.</p>Purity:Min. 95%Pemetrexed impurity C
CAS:<p>Pemetrexed is a drug product that belongs to the group of drugs called antifolate agents. It is used in the treatment of cancer and is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The impurity C is a natural metabolite that can be found in urine as well as in plasma. This impurity has not been identified as a major metabolite of pemetrexed.</p>Formula:C40H40N10O13Purity:Min. 95%Molecular weight:868.81 g/mol5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide
CAS:<p>5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a drug product that was synthesized for research purposes. It is an analytical standard for HPLC and has not been approved for clinical use. 5-[(Hydroxylacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a compound with natural origin and has been classified as an API impurity. This synthetic drug product is custom synthesized to meet the requirements of pharmacopoeia standards.</p>Formula:C16H20I3N3O8Purity:Min. 95%Molecular weight:763.06 g/mol3-(Formylamino)-1H-pyrazole-4-carboxamide
CAS:<p>This product is an organic compound that has a molecular formula of C6H7N3O2. It is a white solid with a melting point of 76.5 °C and an elution time of 7 minutes (range, 1-10 minutes). The detection method is based on the color change from yellow to blue in the presence of dimethylformamide (DMF). This product is used as a solvent for various chemical reactions and can be used in the synthesis of other products. 3-(Formylamino)-1H-pyrazole-4-carboxamide is used in analytical chemistry to determine substances such as pH, ionic strength, and concentration. In addition, this product can be used to quantify substances such as drugs or pharmaceuticals.</p>Formula:C5H6N4O2Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:154.13 g/mol4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride
CAS:<p>Please enquire for more information about 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C20H27N4O4S2•ClPurity:Min. 95%Molecular weight:487.04 g/molAllopurinol impurity A
CAS:<p>Allopurinol is an anticancer drug that is used to treat leukemia and other cancers. Allopurinol impurity A is a byproduct of the production of allopurinol, which has been shown to have anticancer properties. It has been shown to suppress the expression of suppressor genes and up-regulated genes in pancreatic cancer cells. This compound also induces apoptosis in orthotopic liver cells in a process involving activation of caspase 3 and suppression of Akt signaling.</p>Purity:Min. 95%2,4-Diamino-7-pteridinemethanol
CAS:<p>2,4-Diamino-7-pteridinemethanol (2,4-DPPM) is a drug product and an impurity found in the synthesis of 2,4-diamino-7-(2H)-pteridinone. 2,4-DPPM is a synthetic product that can be used as an analytical standard for the determination of aminopyrine in pharmaceuticals and other organic compounds. This compound has been used in pharmacological studies to investigate its effects on various enzymes associated with metabolism. It has also been used as an impurity standard for HPLC analysis of aminopyrine.</p>Formula:C7H8N6OPurity:Min. 95%Molecular weight:192.18 g/molLysine-methotrexate
CAS:<p>Lysine-methotrexate is a monoclonal antibody that binds to the DNA template of Leishmania. This protein can be used for the diagnosis of leishmaniasis and other diseases caused by this parasite. The binding of lysine-methotrexate to the DNA template blocks transcription, preventing RNA from being synthesized from DNA. Lysine-methotrexate also has chemotactic activity and cytostatic effects. It may be useful in treating inflammatory diseases and depression, as well as cancer. Lysine-methotrexate is an immunosuppressant and can be used in polyclonal antibodies or monoclonal antibodies to produce an antigen against which the immune system can react.</p>Formula:C21H27N9O3Purity:Min. 95%Molecular weight:453.5 g/molOXSI-2
CAS:<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Formula:C18H15N3O3SPurity:98%Color and Shape:Dark Orange SolidMolecular weight:353.39Ormetoprim
CAS:<p>Ormetoprim (Ro 5-9754), an antibiotic approved for use in the United States, is used to prevent the spread of disease in freshwater aquaculture.</p>Formula:C14H18N4O2Purity:99.92%Color and Shape:SolidMolecular weight:274.32Migalastat
CAS:<p>Migalastat (GR181413A free base) is an orally administered, competitive inhibitor of α-galactosidase A (α-Gal A), demonstrating an IC50 value of 0.04 μM against</p>Formula:C6H13NO4Color and Shape:SolidMolecular weight:163.17Tenofovir exalidex
CAS:<p>Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant</p>Formula:C28H52N5O5PPurity:99.83%Color and Shape:SolidMolecular weight:569.72Neopterin
CAS:<p>D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ.</p>Formula:C9H11N5O4Purity:99.54%Color and Shape:SolidMolecular weight:253.21Palonosetron
CAS:<p>Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).</p>Formula:C19H24N2OPurity:98%Color and Shape:SolidMolecular weight:296.41Tenofovir diphosphate
CAS:<p>TFV-DP inhibits DNA polymerases, mimics dATP, and is used by HIV-1's reverse transcriptase.</p>Formula:C9H16N5O10P3Color and Shape:SolidMolecular weight:447.17Sumatriptan EP Impurity A
CAS:<p>Sumatriptan EP Impurity A is a metabolite of sumatriptan, a drug product that is used for the treatment of migraine headaches. Sumatriptan EP Impurity A is a natural metabolite of sumatriptan and has been found to be an analytical impurity in the drug product. It has been shown to have anti-inflammatory properties and may be useful for treating arthritis. This impurity can also be synthesized by chemical synthesis or recombinant DNA technology.</p>Formula:C27H37N5O2SPurity:Min. 95%Molecular weight:495.68 g/molMethotrexate-1-monomethyl ester
CAS:<p>Methotrexate-1-monomethyl ester is an impurity found in methotrexate, a drug used to treat cancer and autoimmune disorders. Methotrexate-1-monomethyl ester is a white to off-white crystalline solid that has been synthesized as a custom synthesis. It is used as an analytical standard for the determination of methotrexate in biological fluids and tissues. The chemical purity of this compound can be determined by HPLC, which allows for the identification of any impurities that may be present. Methotrexate-1-monomethyl ester is also used as a pharmacopoeia standard for methotrexate and its metabolites.</p>Formula:C21H24N8O5Purity:Min. 95%Molecular weight:468.47 g/molClopidogrel EP Impurity B hydrochloride
CAS:<p>Please enquire for more information about Clopidogrel EP Impurity B hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C16H16ClNO2S•HClPurity:Min. 95%Molecular weight:358.28 g/molErgotamine Tartrate
CAS:Controlled ProductErgotamine and its saltsFormula:(C33H35N5O5)2·C4H6O6Color and Shape:White Yellow PowderMolecular weight:1162.52764N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic acid
CAS:<p>N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-gamma-glutamyl-L-glutamic acid is used as a research and development purity standard. It is a white crystalline powder that is soluble in water and ethanol. N-[4-[2-(2Amino 4,7dihydro 4oxo 3Hpyrrolo 2,3d]pyrimidin 5yl)ethyl]benzoyl]-L gamma glutamyl L glutamic acid has CAS number 144051 68 3. The drug product is a synthetic compound with high purity. It has been shown to be an analytical reference substance for HPLC standards and to have niche applications in metabolism studies of other drugs.</p>Formula:C25H28N6O9Purity:Min. 95%Molecular weight:556.52 g/molN-Hydroxymethyl Sumatriptan
CAS:<p>N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).</p>Formula:C15H23N3O3SPurity:Min. 95%Molecular weight:325.43 g/mol1-Bromo-3,5-dimethyladamantane
CAS:<p>Intermediate in the synthesis of memantine</p>Formula:C12H19BrPurity:Min. 95%Molecular weight:243.18 g/molButalbital CIII
CAS:Controlled ProductAllobarbital (inn), amobarbital (inn), barbital (inn), butalbital (inn), butobarbital, cyclobarbital(inn), methylphenobarbital (inn), etc.Formula:C11H16N2O3Color and Shape:White PowderMolecular weight:224.11609Codeine Phosphate CII
CAS:Controlled ProductConcentrates of poppy straw; buprenorphine (inn) codeinFormula:C18H21NO3·H3O4PH2OColor and Shape:White Crystalline PowderMolecular weight:406.37 g/molPF 184
CAS:<p>IKKβ inhibitor</p>Formula:C32H32ClFN6O4Purity:98%Color and Shape:SolidMolecular weight:619.09Miglustat hydrochloride
CAS:<p>Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher</p>Formula:C10H22ClNO4Purity:99.85%Color and Shape:SolidMolecular weight:255.74Frovatriptan
CAS:<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Formula:C14H17N3OColor and Shape:SolidMolecular weight:243.3Sumatriptan 3-hydroxy-2-oxo impurity
CAS:<p>Please enquire for more information about Sumatriptan 3-hydroxy-2-oxo impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C14H21N3O4SPurity:Min. 95%Molecular weight:327.4 g/molSorivudine
CAS:<p>Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.</p>Formula:C11H13BrN2O6Purity:99.74%Color and Shape:SolidMolecular weight:349.13Porphobilinogen
CAS:<p>Porphobilinogen act as a phytotoxin, a metabotoxin, and a neurotoxin.</p>Formula:C10H14N2O4Purity:98%Color and Shape:SolidMolecular weight:226.23MRS2500
CAS:<p>MRS2500 is a highly potent and selective platelet P2Y1 receptor antagonist.</p>Formula:C13H18IN5O8P2Purity:98%Color and Shape:SolidMolecular weight:561.161-Benzyl-5-phenylbarbituric acid, 98+%
CAS:<p>1-Benzyl-5-phenylbarbituric acid is useful as a pharmaceutical intermediate in organic synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar p</p>Formula:C17H14N2O3Purity:98+%Color and Shape:Powder, White to creamMolecular weight:294.31Open Ring N-Methyl Clopidogrel Hydrochloride (methyl (S)-2-(2-chlorophenyl)-2-(methyl(2-(thiophen-2-yl)ethyl)amino)acetate, hydrochloride) (DISCONTINUED)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C16H18ClNO2S·HClColor and Shape:White Off-White SolidMolecular weight:359.05136Ergotaminine
CAS:Alkaloids of rye ergot and their derivatives; salts thereof, nesoiFormula:C33H35N5O5Color and Shape:White Off-White Light Grey Crystalline PowderMolecular weight:581.26382Ref: 4Z-O-11138
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