Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65497 products of "Quinazoline and Quinoline Derivatives"
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1,3-Bis(9H-carbazol-4-yloxy)-2-propanol(Carvedilol Impurity)
CAS:Controlled Product<p>Applications A carvedilol Impurity.<br></p>Formula:C27H22N2O3Color and Shape:NeatMolecular weight:422.482-Methyl-4-(morpholin-4-yl)aniline
CAS:Formula:C11H16N2OPurity:97%Color and Shape:SolidMolecular weight:192.2622-[(4-METHYL-1-PIPERAZINYL)METHYL]-6-QUINOLINAMINE
CAS:Purity:95.0%Molecular weight:256.3529968261719Tranilast
CAS:Controlled Product<p>Applications Antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.<br>References Shiota, N., et al.: Brit. J. Pharmacol., 159, 626 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Kawabata, Y., et al.: Eur. J. Pharm. Sci., 39, 256 (2010),<br></p>Formula:C18H17NO5Color and Shape:NeatMolecular weight:327.33Rivaroxaban
CAS:<p>Applications A novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C19H18ClN3O5SColor and Shape:White To BeigeMolecular weight:435.888-methyl-2-(5-methyl-2-thienyl)quinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:283.3500061035156Sarafloxacin
CAS:<p>Applications Sarafloxacin is a quinolone antibiotic drug that was discontinued in 2001. Useful for biological studies and can be detected with colloidal gold test strips.<br>References Jia, F., et al.: Agric. Biotechnol., 8, 172 (2019)<br></p>Formula:C20H17F2N3O3Color and Shape:Light YellowMolecular weight:385.36Desmethyl Nintedanib
CAS:Controlled Product<p>Applications Desmethyl Nintedanib is an impurity of Intedanib (I666650), which is an antitumor agent. Desmethyl Nintedanib was used in the study of synthesizing indolinones as triple angiokinase inhibitors.<br>References Roth, G., et al.: J. Med. Chem., 52, 4466 (2009);<br></p>Formula:C30H31N5O4Color and Shape:NeatMolecular weight:525.6Bufuralol-d9 Hydrochloride
CAS:Controlled Product<p>Applications A β-Adrenergic blocker with peripheral vasodilating activity. Antianginal; antihypertensive.<br>References Francis, R.J., et al.: Eur. J. Clin. Pharmacol., 23, 529 (1982), Pfisterer, M., et al.: J. Cardiovasc. Pharmacol., 6, 417 (1984), Narimatsu, S., et al.: J. Pharmacol. Exp. Ther., 303, 172 (2002), Flanagan, J., et al.: Biochem. J., 380, 353 (2004),<br></p>Formula:C16H15D9ClNO2Color and Shape:NeatMolecular weight:306.887-(Benzyloxy)-4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinoline
CAS:Purity:98%Molecular weight:420.395996093751-(4-morpholinyl)cyclohexanecarboxylic acid hydrochloride hydrate
Purity:95.0%Molecular weight:267.751-(Mercaptomethyl)cyclopropaneacetic Acid
CAS:Controlled Product<p>Applications An intermediate of Montelukast.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C6H10O2SColor and Shape:NeatMolecular weight:146.21Argatroban
CAS:<p>Argatroban (MCI-9038), a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.</p>Formula:C23H36N6O5SPurity:99.77% - >99.99%Color and Shape:White To Off-White Crystalline SolidMolecular weight:508.638-chloro-2-pyridin-4-ylquinoline-4-carboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:284.700012207031252-(2,5-Dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Purity:97.0%Molecular weight:288.3599853515625Desmethyl 2N-Nitroso Mirtazapine-d6 (major)
Controlled ProductFormula:C16D6H10N4OColor and Shape:Neat3-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one
CAS:Controlled ProductFormula:C6H5F3N4OColor and Shape:Off White To Light GreyMolecular weight:206.13Dichlorodenafil
CAS:Controlled Product<p>Applications Dichlorodenafil is an unapproved Sildenafil (S435001) functions by inhibiting the phosphodiesterase type 5 enzyme (PDE-5).<br>References Kim, J.Y., et al.: Chem. Pharm. Bull., 61, 572 (2013)<br></p>Formula:C19H20Cl2N4O2Color and Shape:SolidMolecular weight:407.29Descyano Cimetidine Dihydrochloride Salt
CAS:<p>Impurity Cimetidine EP Impurity D<br>Stability Hygroscopic<br>Applications Descyano Cimetidine Dihydrochloride Salt (Cimetidine EP Impurity D) is a metabolite of Cimetidine (C441650); a competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output.<br>References Brimblecombe, R.W., et al.: J. Int. Med. Res., 3, 86 (1975); Durant, G.J., et al.: J. Med. Chem., 20, 901 (1977)<br></p>Formula:C9H17N5S·2ClHColor and Shape:NeatMolecular weight:300.256-Iodo-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:Purity:98%Molecular weight:329.0929870605469Clofentezine
CAS:Controlled Product<p>Applications Clofentezine is a mite growth regular and an tetrazine based acaricide. Clofentezine is used in agriculture for the protection of ornamentals, food and non-food crops in the field.Used as a standard for Pesticide detection. Clofentezine is used in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bakirci, G.T., et al.; Food. Chem., 135, 1901 (2012); Ay, R., et al.: Insect. Sci., 18, 503 (2011);<br></p>Formula:C14H8Cl2N4Color and Shape:NeatMolecular weight:303.15Vortioxetine Hydrobromide
CAS:<p>Applications Vortioxetine Hydrobromide is a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br>References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Formula:C18H22N2S·BrHColor and Shape:Beige To Light YellowMolecular weight:379.358Methylphenidate Hydrochloride
CAS:Controlled Product<p>Applications Controlled substance (stimulant). CNS stimulant. Four isomers of Methylphenidate are known to exist. One pair of threo isomers and one pair of erythro are distinguished, from which only d-threo-Methylphenidate exhibits the pharmacologically usually desired effects. This compound is a 4:1 mixture of rac-erythro (M325670) and rac-threo (M325671).<br>References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),<br></p>Formula:C14H19NO2·ClHColor and Shape:White To Off-WhiteMolecular weight:269.7710H-Phenothiazine
CAS:Purity:95.0%Color and Shape:Solid, Crystalline Powder or Flakes or Pellets or PowderMolecular weight:199.270004272460946-Methyl-2-pyridin-4-yl-quinoline-4-carboxylic acid
CAS:Purity:90.0%Molecular weight:264.283996582031255-(1,3-Dioxolan-2-yl)-2-(4-isopropylbenzoyl)thiophene
CAS:Purity:97.0%Molecular weight:302.3900146484375N-Nitroso Betahistine
CAS:<p>Applications N-Nitroso Betahistine is an impurity of Betahistine, which is most commonly used to treat the symptoms of Ménière's disease and vertigo. Vasodilator.<br>References Gilligan, P., et al.: J. Med. Chem., 43, 1641 (2000), Keller, P., et al.: Bioorg. Med. Chem., 8, 1213 (2000), Hauger, R., et al.: Pharmacol. Rev., 55, 21 (2003), Han, X., et al.: Bioorg. Med. Chem. Lett., 15, 3870 (2005)<br></p>Formula:C8H11N3OColor and Shape:Colourless To Light YellowMolecular weight:165.1922-Bromoacetic Acid
CAS:<p>Applications Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);<br></p>Formula:C2H3BrO2Color and Shape:Light YellowMolecular weight:138.954-(5-(2,6-Dimethoxyphenyl)-3-(methoxycarbonyl)-1H-pyrazol-1-yl)-3-isopropylbenzoic acid
CAS:Purity:95%Molecular weight:424.45300292968754-Phenylthiophene-2-carboxylic acid
CAS:Formula:C11H8O2SPurity:97%Color and Shape:SolidMolecular weight:204.241-Isopropenyl-2-benzimidazolidinone
CAS:Controlled Product<p>Applications 1-Isopropenyl-2-benzimidazolidinone (cas# 52099-72-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C10H10N2OColor and Shape:NeatMolecular weight:174.20rac Metanephrine Hydrochloride Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Epinephrine (E588585). A naturraly occurring derivative of Epinephrine, found in urine and in certain tissues.<br>References Eisenhofer, G., et al.: J. Clin. Endocrinol. Metab., 82, 3864 (1997), Akiyama, T., et al.: Cardiovasc. Res., 49, 78 (2001), Burke, W., et al.: Brain Res., 891, 218 (2001),<br></p>Formula:C10H15NO3·ClHColor and Shape:White To GreyMolecular weight:233.697-Chloro-1-Ethyl-6-Fluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid Ethyl Ester
CAS:Controlled Product<p>Impurity Norfloxacin Impurity 5<br>Applications 7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester (Norfloxacin Impurity 5) is an impurity of Norfloxacin (N681000), an antibacterial agent and a contaminant of emerging concern (CECs).<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),<br></p>Formula:C14H13ClFNO3Color and Shape:Off-White To BeigeMolecular weight:297.71(R)-Omeprazole Sodium Salt
CAS:<p>Applications R-Form of Omeprazole. Gastric proton-pump inhibitor.<br>References Stenhoff, H., et al.: J. Chromatogr., 734, 191 (1999), Johnson, D.A., et al.: Expert Opin. Pharmacother., 4, 253 (2003),<br></p>Formula:C17H18N3O3S·NaColor and Shape:NeatMolecular weight:367.402-Chlorothiophene
CAS:Controlled Product<p>Applications 2-Chlorothiophene (cas# 96-43-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C4H3ClSColor and Shape:NeatMolecular weight:118.584-(4-(3-(1H-Pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl)phenyl)morpholine
CAS:Purity:97.0%Molecular weight:346.39401245117191-(4-Chloro-phenyl)-3-(4-methylsulfanyl-phenyl)-1H-pyrazole-5-carboxylic acid
CAS:Molecular weight:344.809997558593753-Dimethylaminopropyl-2-benzylaminobenzoate Hydrochloride
CAS:Formula:C19H24N2O2·ClHColor and Shape:NeatMolecular weight:348.874,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
CAS:<p>Applications 4,5-Dichloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C19H17Cl2N3O5SColor and Shape:NeatMolecular weight:470.33trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol
CAS:<p>Applications trans-4-[[(2-Amino-5-bromophenyl)methyl]amino]-cyclohexanol is an impurity of Ambroxol (A575900), a bronchosecretolytic drug and a metabolite of Bromohexine.<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>Formula:C13H19BrN2OColor and Shape:NeatMolecular weight:299.216-Methoxy-2-naphthol
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications 6-Methoxy-2-naphthol is a reactant in the development of sirtuin inhibitors from pyrazolone and isoxazol-5-one cambinol analogs.<br>References Mahajan, S.S., et. al.: J. Med. Chem., 57, 3283 (2014)<br></p>Formula:C11H10O2Color and Shape:NeatMolecular weight:174.207-BROMO-1-(4-HYDROXY-2-METHYLPHENYL)-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXAMIDE
CAS:Purity:95.0%Molecular weight:372.0109543761,3-Dioxo-2-pyridin-3-ylmethyl-2,3-dihydro-1H-isoindole-5-carboxylic acid
CAS:Purity:95.0%Molecular weight:282.2550048828125ETHYL 5-AMINO-1-(QUINOXALIN-2-YL)-1H-PYRAZOLE-4-CARBOXYLATE
CAS:Purity:95.0%Molecular weight:283.29098510742194-(4-Methoxyphenyl)thiophene-2-carboxylic acid
CAS:Formula:C12H10O3SPurity:95.0%Color and Shape:SolidMolecular weight:234.272-Methyl-2-propyl-1,3-propanediol
CAS:Controlled Product<p>Applications An intermediate in the synthesis of Carisoprodol.<br></p>Formula:C7H16O2Color and Shape:NeatMolecular weight:132.207-(Diethylamino)-3-(thiophen-2-yl)-2H-chromen-2-one
CAS:Purity:98% HPLC,TMolecular weight:299.39001464843757-chloro-4-methoxy-N-(pyridin-2-ylmethyl)benzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:305.77999877929691-(10H-Phenothiazin-2-yl)propan-1-one
CAS:Purity:95%Color and Shape:SolidMolecular weight:255.33999633789062(R)-Sulindac
CAS:Controlled Product<p>Applications (R)-Sulindac is the R-epimer metabolite of Sulinac (S699215). (S)-Sulindac increases the activity of the P 450 system better than (R)-Sulindac, but both epimers increase primarily the enzymes that oxidize (R)-Sulindac.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Duggan, D., et al.: J. Pharmacol. Exp. Ther., 1977, 201, 8 (1977), Hamman, M., et al.: Biochem. Pharmacol., 60, 7 (2000), Grimaud, R., et al.: J. Biol. Chem., 276, 48915 (2001),<br></p>Formula:C20H17FO3SColor and Shape:NeatMolecular weight:356.414-Amino-N-pyridin-3-ylmethylbenzamide
CAS:Formula:C13H13N3OPurity:97%Color and Shape:SolidMolecular weight:227.267rac 7-Hydroxy Efavirenz
CAS:Controlled ProductFormula:C14H9ClF3NO3Color and Shape:NeatMolecular weight:331.67N-Nitroso Desmethyl Rizatriptan
Controlled ProductFormula:C14H16N6OColor and Shape:NeatMolecular weight:284.316(3-Methoxypyridin-4-yl)boronic acid hydrate
CAS:Formula:C6H10BNO4Purity:95.0%Color and Shape:SolidMolecular weight:170.96N-(5-chloropyridin-2-yl)-2-(4-cyanobenzamido)-5-methoxybenzamide
CAS:Purity:97%Molecular weight:406.8299865722656Nicarbazine
CAS:Controlled Product<p>Applications Nicarbazine, is a coccidiostat, which is an antiprotozoal agent that acts upon Coccidia parasites.<br>References Ksenija Sinigoj, G., et al.: Slovenski Kemijski Dnevi, (2012); Kyung-Woo, L., et al.: Han'guk Kagum Hakhoechi, 39, 17 (2012);<br></p>Formula:C13H10N4O5·C6H8N2OColor and Shape:NeatMolecular weight:426.38Desidustat
CAS:<p>Stability Hygroscopic<br>Applications Desidustat, is an HIF hydroxylase inhibitor.<br></p>Formula:C16H16N2O6Color and Shape:NeatMolecular weight:332.312-Ethoxybenzamidine Hydrochloride
CAS:Controlled Product<p>Applications 2-Ethoxybenzamidine hydrochloride is an impurity of Vardenafil (diHCl salt: V098001), a phosphodiesterase type 5 inhibitor that is used to treat men of varying aetiology with erectile dysfunction.<br>References Hellstrom, W., et al.: J. Andro., 23, 763 (2002); Keating, G. & Scott, L.: Drugs, 63, 2673 (2003); Krishnaiah, C., et al.: Anal. Chem. Ind. J., 8, 284 (2009); Porst, H., et al.: Int. J. Imp. Res., 13, 192 (2001)<br></p>Formula:C9H13ClN2OColor and Shape:NeatMolecular weight:200.67Kynurenic Acid-d5
CAS:Controlled Product<p>Applications A labelled product of L-Tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties.<br>References Wejksza, K., et al.: Pharmacol. Rep., 61, 751 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Di Natale, B., et al.: Toxicol. Sci., 115, 89 (2010),<br></p>Formula:C102H5H2NO3Color and Shape:BeigeMolecular weight:194.20[1-(2-thienyl)butyl]amine hydrochloride
CAS:Formula:C8H14ClNSPurity:95.0%Color and Shape:SolidMolecular weight:191.72rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol
CAS:Controlled Product<p>Impurity Metoprolol USP Related Compound B<br>Applications An intermediate for the synthesis of β-chlorohydrins and β-chloroamines. An impurity found in metoprolol. Metroprolol USP Related Compound B.<br>References Moore, R., et al.: Marine Natural Products, 1, 43 (1978),<br></p>Formula:C12H17ClO3Color and Shape:ColourlessMolecular weight:244.71R-(-)-N-Demethyl Deprenyl-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Deprenyl (D288641) (Selegiline).<br>References Dyck, L., et al.: Drug Metab. Dispos., 29, 1156 (2001), Damaj, M., et al.: J. Pharmacol. Exp. Ther., 320, 250 (2007),<br></p>Formula:C12H10D5NColor and Shape:NeatMolecular weight:178.29Tamsulosin
CAS:<p>Tamsulosin: an alpha1A blocker for easing urination in BPH by relaxing prostate and bladder muscles.</p>Formula:C20H28N2O5SPurity:99.93%Color and Shape:White CrystalsMolecular weight:408.512-(Thiophene-2-sulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
CAS:Purity:97%Molecular weight:323.3800048828125
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