Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65576 products of "Quinazoline and Quinoline Derivatives"
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4-OXO-5-(THIOPHEN-2-YLMETHYL)-4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE-3-CARBOXYLIC ACID
CAS:Purity:95.0%Molecular weight:277.29998779296875N-Chloro Ethyl ThioTEPA
CAS:Controlled Product<p>Stability Hygroscopic, Moisture Sensitive<br>Applications N-Chloro Ethyl ThioTEPA is an impurity of ThioTEPA which is an alkylating agent used to treat cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Maanen, M., et al.: Cancer Treatment Rev., 26, 257 (2000); Sykes, M., et al.: Cancer, 6, 142 (1953)<br></p>Formula:C6H13ClN3PSColor and Shape:White To Off-WhiteMolecular weight:225.68Nimodipine
CAS:<p>Applications A dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral). Neuroprotective & Neuroresearch products.<br>References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),<br></p>Formula:C21H26N2O7Color and Shape:NeatMolecular weight:418.44Vismodegib
CAS:Controlled Product<p>Applications Vismodegib targets the Hedgehog (Hh) pathway. Inhibition of the Hh signaling may be effective in the treatment and prevention of many types of human cancers. Potent Hedgehog inhibitor.<br>References Gupta, S. et al.: Ther. Advances in Med. Oncology 2,237(2010)<br></p>Formula:C19H14Cl2N2O3SColor and Shape:Off-WhiteMolecular weight:421.30Alogliptin-d3
CAS:Controlled Product<p>Applications Labelled Alogliptin (A575425). It is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.<br>References Lynn, F., et al.: Diabetes, 50, 1004 (2001), Trumper, A., et al.: J. Endocrinol., 174, 233 (2002), Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009),<br></p>Formula:C182H3H18N5O2Color and Shape:NeatMolecular weight:342.41Trametinib
CAS:Controlled Product<p>Applications Used in the systematic treatment of advanced cutaneous melanoma. An EGFR kinase inhibitor and potent MEK inhibitor.<br>References Ercan, D. et al.: Canc. Disc., 2, 934 (2012); Mackiewicz-Wysocka, M. et al.: Exp. Opin. Investig. Drugs., 22, 181 (2013);<br></p>Formula:C26H23FIN5O4Color and Shape:Off-WhiteMolecular weight:615.39Irbesartan-d4
CAS:Controlled Product<p>Applications Irbesartan-d4 is the labeled analogue of Irbesartan (I751000), an angiotensin II type 1 (AII1)-receptor antagonist.<br>References Gillis, J.C. and Markham, A.: Drugs, 54, 885 (1997); Chando, T.J., et al.: Drug. Metabol. Dispos., 26, 408 (1998); Massie, B., et al.: New Eng. J. Med., 359, 2456 (2008); Ren, X., et al.: Pharmacol., 83, 80 (2009)Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals<br></p>Formula:C25H24D4N6OColor and Shape:NeatMolecular weight:432.55Ivacaftor Carboxylic Acid Lactone
CAS:Controlled ProductFormula:C24H24N2O4Color and Shape:NeatMolecular weight:404.46Felbamate-d4
CAS:Controlled Product<p>Applications Antiepileptic, structurally similar to meprobamate.<br>References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),<br></p>Formula:C11H10D4N2O4Color and Shape:NeatMolecular weight:242.267Gefitinib-d6
CAS:Controlled Product<p>Applications Gefitinib-d6 is the labeled version of Gefitinib (G304000), which is an antineoplastic.<br>References Anderson, N.G., et al.: Int. J. Cancer, 94, 774 (2001), Hirata, A., et al.: Cancer Res., 62, 2554 (2002), Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003), Tamura, K., et al.: Expert Opin. Pharmacother., 6, 985 (2005)<br></p>Formula:C22D6H18ClFN4O3Color and Shape:NeatMolecular weight:452.9395-(Benzo[1,3]-dioxol-5yl)-picolinic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:243.21800231933594Vildagliptin Amide
CAS:Controlled Product<p>Impurity Vildagliptin Amide Impurity<br>Applications N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-prolinamide is an impurity of Vildagliptin (V305000) which is an oral anti-hyperglycemic agent that inhibit dipeptidyl peptidase 4 (DPP-4).<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formula:C17H27N3O3Color and Shape:Off-WhiteMolecular weight:321.41Nifursol (~90%)
CAS:Controlled Product<p>Applications A medicinal, prophylactic additive in animal feeds, protecting poultry from histomoniasis.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Kowalski, P., et al.: J. Pharm. Biomed. Anal., 32, 937 (2003), Khlebnikov, A., et al.: Bioorg. Med. Chem., 16, 9302 (2008), Schepetkin, I., et al.: Mol. Pharmacol., 74, 392 (2008),<br></p>Formula:C12H7N5O9Purity:~90%Color and Shape:NeatMolecular weight:365.21Methyl 4’-[[2-n-Propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)-benzimidazol-1-yl]methyl]biphenyl-2-ca
CAS:Formula:C34H32N4O2Color and Shape:YellowMolecular weight:528.64Maraviroc
CAS:Controlled ProductFormula:C29H41F2N5OColor and Shape:White To Off-WhiteMolecular weight:513.67Chloropretadalafil
CAS:<p>Applications An intermediate in the synthesis of Tadalafil (T004500), which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003),<br></p>Formula:C22H19ClN2O5Color and Shape:White To Light Orange ColourMolecular weight:426.851-Phenyl-1-(2-pyridyl)ethanol
CAS:<p>Impurity Doxylamine EP Impurity B<br>Stability Light Sensitive<br>Applications Doxylamine intermediate.<br>References Rennison, D., et al.: Bioorg. Med. Chem., 15, 2963 (2007),<br></p>Formula:C13H13NOColor and Shape:Off-White To Light YellowMolecular weight:199.254-Anilino-4-oxobutanoic Acid
CAS:Controlled Product<p>Applications The metabolite (MII) of Suberoylanilide Hydroxamic Acid (S688700).<br>References Sun, W.S., et al.: J. Med. Chem., 46, 5619 (2003)<br></p>Formula:C10H11NO3Color and Shape:NeatMolecular weight:193.20Aripiprazole N4-Oxide
CAS:Controlled Product<p>Impurity Aripiprazole Impurity 9<br>Applications Aripiprazole N4-Oxide is a metabolite of anti-psychotic drug, Aripiprazole (A771000). Aripiprazole Impurity 9<br>References Rowley, M., et al.: J. Med. Chem., 44, 477 ( 2001), Ozdemir, V., et al.: Curr. Opin. Invest Drugs 2002, 3, 113,,,4) Jordan, S; European Journal Pharmacol 2002, 441, 137<br></p>Formula:C23H27Cl2N3O3Color and Shape:NeatMolecular weight:464.38Propoxyphenyl Thioaildenafil
CAS:Controlled Product<p>Applications Propoxyphenyl Thioaildenafil is an analogue of Thioaildenafil (T344365). Propoxyphenyl Thioaildenafil is a phosphodiesterase-5 inhibitor (PDE-5) that has been found in health supplements.<br>References Kee, C., Ge, X., Koh, H., Low, M.: J. Pharmaceut. Biomed., 70, 265 (2012)<br></p>Formula:C24H34N6O3S2Color and Shape:NeatMolecular weight:518.75-Aminothiophene-2-carbonitrile
CAS:Formula:C5H4N2SPurity:98%Color and Shape:SolidMolecular weight:124.16Indazole-3-carboxylic Acid
CAS:Controlled Product<p>Applications Indazole-3-carboxylic Acid is an indole derivatives useful in treatment of pain and inflammation.<br>References Khanna P., et al.: Biochemistry, 40, 1441 (2001);<br></p>Formula:C8H6N2O2Color and Shape:NeatMolecular weight:162.145(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid
CAS:Controlled Product<p>Applications (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid has been used as a reactant for the preparation of dipeptidyl peptidase-4 (DPP4) inhibitors for the treatment of type 2 diabetes, such as sitagliptin.<br>References Kim, H.J., et. al.: Bioorg. Med. Chem. Lett., 22, 5545 (2012)<br></p>Formula:C15H18F3NO4Color and Shape:NeatMolecular weight:333.30Levetiracetam Carboxylic Acid
CAS:Controlled ProductFormula:C8H13NO3Color and Shape:White To Off-WhiteMolecular weight:171.19Ethyl Difluoroacetate
CAS:Controlled Product<p>Applications Ethyl difluoroacetate<br></p>Formula:C4H6F2O2Color and Shape:NeatMolecular weight:124.091-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine
CAS:Controlled ProductFormula:C19H29NO2Color and Shape:WhiteMolecular weight:303.44Piperazin-1-yl(quinoxalin-6-yl)methanone hydrochloride
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:278.739990234375N-Nitroso Clonidine
CAS:Controlled ProductFormula:C9H8Cl2N4OColor and Shape:NeatMolecular weight:259.09Retigabine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A new experimental anticonvulsant drug. Anxiolytic.<br>References Dailey, J.W.; et al.: Neuroscience Lett., 195, 77 (1995), Korsgaard, M.P.G., et al.: J. Pharmacol. Exp. Ther., 314, 1, 282 (2005),<br></p>Formula:C16H18FN3O2Color and Shape:NeatMolecular weight:303.33Nitisinone
CAS:<p>Applications Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I.<br>References Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998),<br></p>Formula:C14H10F3NO5Color and Shape:NeatMolecular weight:329.235-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole
CAS:Controlled Product<p>Applications Sitagliptin intermediate. An anti-hypertensive agent for the treatment of diabetes and hypertension.<br>References Sarges, R, et al.: J. Med. Chem., 33, 2240 (1990),<br></p>Formula:C4H2ClF3N2OColor and Shape:NeatMolecular weight:186.52Sulindac
CAS:Controlled Product<p>Applications Sulindac is a non-steroidal anti-inflammatory drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bjorkman., et al.: Am. J. Med., 105, 17S (1998), Thakur, et al.: Am. J. Hypertens., 12, 925 (1999),<br></p>Formula:C20H17FO3SColor and Shape:Yellow To Dark OrangeMolecular weight:356.416-Chloro-2-cyclopropyl-4-(trifluoromethyl)-quinoline
CAS:Controlled Product<p>Impurity Efavirenz USP Related Compound C/ Efavirenz Quinoline Impurity<br>Applications 6-Chloro-2-cyclopropyl-4-(trifluoromethyl)-quinoline is an impurity of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor and antiviral agent.<br>References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995), Jiang, B., et al.: Euro. J. Org. Chem., 16, 2693 (2008); Ribeiro, J.A., et al.: J. Pharma. Biomed. Anal., 43, 298 (2007);<br></p>Formula:C13H9ClF3NColor and Shape:NeatMolecular weight:271.67Tricyclazole
CAS:Controlled Product<p>Applications Tricyclazole is an common active ingredient in several commercial fungicide products used to control rice blast fungus, in transplanted and direct-seeded rice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dhingani, J.C., et al.: J. Pure. App. Microbiol., 6, 1683 (2012); Jeong, S.A., et al.: Bull. Environ. Contamin. Toxicol., 89, 1181 (2012);<br></p>Formula:C9H7N3SColor and Shape:BeigeMolecular weight:189.248-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one
CAS:Controlled Product<p>Impurity CLOZAPINE EP IMPURITY A<br>Stability Store in Freezer<br>Applications A useful intermediate for the preparation of pharmaceutical actives and fine chemicals. Antipsychotic drug.<br>References Venkat Rao, S., Arab. J. Chem., 13, 6040 (2020)<br></p>Formula:C13H9ClN2OColor and Shape:NeatMolecular weight:244.68Deferiprone
CAS:Controlled Product<p>Applications A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transferrin and ferritin in vitro.<br>References Kontoghiorghes, G.J.: Lancet I, 817 (1985), Kontoghiorghes, G.J., et al.: Br. J. Haematol., 62, 607 (1986), Kontoghiorghes, G.J., et al.: Biochem. Biophys. Acta, 869, 141 (1986), Kontoghiorghes, G.J., et al.: Arzneim.-Forsch., 37, 1099 (1987),<br></p>Formula:C7H9NO2Color and Shape:White To Off-WhiteMolecular weight:139.15Lansoprazole
CAS:<p>Applications Used as a gastric proton pump inhibitor. An antiulcerative. May limit the severity of tuberculosis (see Chem. and Eng. News. p. 28 July 20 (2018)).<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006), Chem. and Eng. News. p. 28 July 20 (2018)<br></p>Formula:C16H14F3N3O2SColor and Shape:White To Light BeigeMolecular weight:369.36N-(3-(2-Chlorobenzoyl)-5-ethylthiophen-2-yl)-2-(1,3-dioxoisoindolin-2-yl)acetamide
CAS:Purity:97%Molecular weight:452.9100036621094Suvorexant
CAS:Controlled Product<p>Applications Suvorexant (MK-4305) is a dual (non-selective) orexin receptor antagonist in development by Merck & Co. for the treatment of insomnia. It works by turning off wakefulness rather than by inducing sleep. Users of higher doses had an increased rate of suicidal ideation.<br>References Cox, C., et al.: J. Med. Chem., 53, 5320 (2010); Baxter, C., et al.: Org. Process Res. Dev., 15, 367 (2011); Winrow, C., et al.: J. Neurogenet., 25, 52 (2011); Mieda, M., et al.: CNS Drugs, 27, 83 (2013); Osborne, R.: Nat. Rev. Drug Discov., 12, 492 (2013)<br></p>Formula:C23H23ClN6O2Color and Shape:WhiteMolecular weight:450.92rac-cis-7-Hydroxy Pramipexole
CAS:Controlled Product<p>Impurity Pramipexole Related Compound G<br>Applications Pramipexole derivative used for the preparation of (S)-Pramipexole via resolution of 2,6-diamino-7-hydroxy-4,5,6,7-tetrahydrobenzothiazole derivatives.<br>References Validation of a column liquid chromatographic method for the analysis of pramipexole and its 5 impurities. Journal of AOAC International (2010), 93(4), 1102-1112. Gegoe, Csaba Lehel; Fejes, Imre; Garaczi, Sandor; Kovacs, Imre; Lukacs, Ferenc; Majercsik, Orsolya; Schneider, Geza. Process for preparation of (S)-pramipexole via resolution of 2,6-diamino-7-hydroxy-4,5,6,7-tetrahydrobenzothiazole derivatives. Eur. Pat. Appl. (2008), 26pp. CODEN: EPXXDW EP 1878731<br></p>Formula:C10H17N3OSColor and Shape:NeatMolecular weight:227.33Apremilast
CAS:<p>Applications Apremilast is an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis.<br>References Gan, E., et al.: BioDrugs, 27, 359 (2013); Pathan, E., et al.: Annal. Rheum. DIs., 72, 1475 (2013);<br></p>Formula:C22H24N2O7SColor and Shape:NeatMolecular weight:460.503-Chloro-N-methylpropan-1-amine Hydrochloride
CAS:Controlled Product<p>Applications 3-Chloro-N-methylpropan-1-amine Hydrochloride can be used as reactant/reagent in oxidative metabolism of ferrocene analogs of tamoxifen: characterization and antiproliferative activities of metabolites.<br>References Richard, M. A., et al.: ChemMedChem, 10, 981-990 (2015)<br></p>Formula:C4H10ClN•(HCl)Color and Shape:NeatMolecular weight:107.5836465-Hydroxy Omeprazole-d3 Sodium Salt
CAS:Controlled ProductFormula:C17H15D3N3NaO4SColor and Shape:White To Light YellowMolecular weight:386.421-CYCLOPROPYL-6,7,8-TRIFLUORO-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:283.205993652343759-Piperazino Levofloxacin Impurity
CAS:Controlled Product<p>Applications A degradation product of Levofloxacin (L360000). Levofloxacin impurity.<br>References ierens, C., et al.: J. Pharm. Biomed. Anal., 22, 763 (2000), Kitade, T., et al.: Chem. Pharm. Bull., 51, 53 (2003), Liang, Y., et al.: Anal. Chim. Acta, 510, 21 (2004),<br></p>Formula:C18H20FN3O4Color and Shape:NeatMolecular weight:361.3683-(4-Fluoro-phenyl)-1-methyl-1H-pyrazole-4-carbaldehyde
CAS:Formula:C11H9FN2OPurity:95.0%Color and Shape:Solid, Light yellow powderMolecular weight:204.2042-Nitrobenzaldehyde
CAS:<p>Applications 2-Nitrobenzaldehyde is a benzaldhyde with a nitro group substituted in the ortho position. 2-Nitrobenzaldehyde is used in the preparation of dyes and colorants such as Indigo carmine. 2-Nitrobenzaldehyde gas been shown to be a useful photoremovable protecting group as well as in the preparation of more effective ones such as o-Nitrophenylethylene glycol.<br>References Gravel, D. et al.: Can. J. Chem., 61, 400 (1983); Sebej, P. et al.: J. Org. Chem., 74, 8647 (2009); Das, A. et al.: J. Ind. Che,. Soc., 49, 993 (1972);<br></p>Formula:C7H5NO3Color and Shape:NeatMolecular weight:151.122-(Aminomethyl)-1-ethylpyrrolidine
CAS:Controlled ProductFormula:C7H16N2Color and Shape:Colourless To Light YellowMolecular weight:128.224'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile
CAS:Controlled Product<p>Impurity Irbesartan Cyano Impurity<br>Applications A butyldiazaspirononenone derivative used in the preparation of acetylcholinesterase inhibitors. An impurity found in Irbesartan (I751000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kavitha, C.V. et al.: Bioorg. Med. Chem., 15, 7391 (2007);<br></p>Formula:C25H27N3OColor and Shape:NeatMolecular weight:385.50Fluralaner-13C2,15N,D2
CAS:Controlled ProductFormula:C2C20D2H15Cl2F615NN2O3Color and Shape:Off-WhiteMolecular weight:561.276(5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone
CAS:Controlled Product<p>Applications (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone is an intermediate used in the synthesis of dronedarone hydrochloride (I), a class III antiarrhythmia drug for the prevention of cardiac arrhythmias such as atrial fibrillation.<br>References Mali, A. C., et al.: Org. Proc. Res. Dev., 17, 863 (2013)<br></p>Formula:C30H42N2O3Color and Shape:NeatMolecular weight:478.675,6-Dehydro-17b-dutasteride
CAS:Controlled Product<p>Impurity Dutateride EP Impurity G<br>Applications 5,6-Dehydro-dutasteride (Dutateride EP Impurity G) is an impurity in the synthesis of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Formula:C27H28F6N2O2Color and Shape:NeatMolecular weight:526.51Glycopyrrolate Bromide-d3 (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Labelled analogue of Glycopyrrolate Bromide, a novel pharmaceutical compound based on PDE IV inhibitors. Glycopyrrolate Bromide is used in the treatment of respiratory complaints.<br>References Gomez, et al.: Br. J. Anaesth., 74, 549 (1995);<br></p>Formula:C19H25D3NO3·BrColor and Shape:NeatMolecular weight:401.35DL-threo-Ritalinic Acid-d10 (Major)
CAS:Controlled ProductFormula:C13H7D10NO2Color and Shape:NeatMolecular weight:229.34N-Benzoyl-DL-tyrosyl-N',N'-dipropylamide
CAS:Controlled Product<p>Applications N-Benzoyl-DL-tyrosyl-N',N'-dipropylamide is a metabolite of the antispasmodic agent Tiropramide (T446900). Tiropramide impurity C.<br>References Setnikar, I. et al.: Arzneim.-Forsch., 39, 328 (1989);<br></p>Formula:C22H28N2O3Color and Shape:Off-WhiteMolecular weight:368.474-{3-[4-(Trifluoromethyl)phenyl]-1H-pyrazol-4-yl}pyridine
CAS:Formula:C15H10F3N3Purity:95.0%Molecular weight:289.261Minoxidil Sulfate-d10
CAS:Controlled Product<p>Stability Light Sensitive - Protect from Light, Store in Freezer<br>Applications Labelled Minoxidil sulfate (M345100). Minoxidil sulfate is the active metabolite of Minoxidil and is a potent (IC50=0.14µM) vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener.<br>References Nakaya, Y., et al.: J. Dermatol. Sci., 7 (Suppl.), S104-S108 (1994), Ohtsuyama, M., et al.: J. Pharmacol. Exp. Ther., 269(2), 823 (1994), Andersson, K.E., et al.: Pharmacol. Toxicol., 70, 244 (1992), Bray, K.M., et al.: J. Biol. Chem., 267, 11689 (1992), Saitoh, M. et al.: Biochem. Biophys. Res. Commun., 140, 280 (1986)<br></p>Formula:C9H5D10N5O4SColor and Shape:NeatMolecular weight:299.37Iso Loratadine
CAS:Controlled Product<p>Impurity Loratadine EP Impurity E<br>Applications Iso Loratadine (Loratadine EP Impurity E) is a Loratadine (L469575) impurity. An isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.<br>References Billah., et al.: Lipids, 26, 1172 (1991), Piwinski., et al.: J. Med. Chem., 34, 457 (1991),<br></p>Formula:C22H23ClN2O2Color and Shape:NeatMolecular weight:382.88N-Desmethyl Diphenhydramine Hydrochloride
CAS:<p>Applications N-Desmethyl Diphenhydramine is an impurity of Diphenhydramine (D486900) with antihistaminic activity.<br>References Nauta, W. T. et al.: Med. Chem., Spec. Contrib. Int. Symp., 3rd, 125 (1973);<br></p>Formula:C16H19NO·ClHColor and Shape:White To Light BeigeMolecular weight:277.794-Phenyl-2-(4-pyridyl)thiazole-5-carboxylic acid
CAS:Color and Shape:SolidMolecular weight:282.32000732421875Loxapine N-Oxide
CAS:<p>Stability Hygroscopic, Light Sensitive<br>Applications Loxapine N-Oxide is a metabolite of Loxapine (L472750), a D2/D4-Dopamine receptor antagonist. It is a serotonergic receptor antagonist that acts as a dibenzoxazepine antipsychotic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shen, Y., et al.: J. Biol. Chem., 268, 18200 (1993), Fiorella, D., et al.: Psychopharmacology, 121, 347 (1995), Glusa, E., et al.: Br. J. Pharmacol., 130, 692 (2000)<br></p>Formula:C18H18ClN3O2Color and Shape:NeatMolecular weight:343.81N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine Formamide Hydrochloride
CAS:Controlled Product<p>Impurity Alfuzosin Hydrochloride EP Impurity E<br>Applications Alfuzosin (A532000) impurity. Alfuzosin (A532000) is an α1-Adrenoceptor antagonist structurally similar to Prozosin. Antihypertensive. Used in treatment of benign prostatic hypertrophy. (Alfuzosin Hydrochloride EP Impurity E )<br>References Ramage, A.G., et al.: Eur. J. Pharmacol., 129, 307 (1986), Deering, A.H.,: Brit. J. Clin. Pharmacol., 25, 417 (1988), Priolo, L.D., et al.: Eur. J. Clin. Pharmacol., 35, 25 (1988),<br></p>Formula:C15H21N5O3·HClColor and Shape:White To Off-WhiteMolecular weight:319.37 + (36.46)2,5-Dioxopyrrolidin-1-yl 6-hydrazinylnicotinate hydrochloride
CAS:Purity:98%Molecular weight:286.67001342773444-Chloro-1H -pyrazol-3-ylamine hydrochloride
CAS:Formula:C3H5Cl2N3Purity:95.0%Color and Shape:SolidMolecular weight:153.994’-O-Benzyloxy Ezetimibe
CAS:Controlled Product<p>Impurity Ezetimibe Benzyl Ether Impurity<br>Applications Protected Ezetimibe, used for the synthesis of related derivatives.<br>References Raman, B., et al.: J. Pharm. Biomed. Anal., 52, 73 (2010),<br></p>Formula:C31H27F2NO3Color and Shape:NeatMolecular weight:499.55Oxyphenbutazone
CAS:<p>Applications Anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yoshida, F., et al.: J. Med. Chem., 43, 2575 (2000), Chen, M., ET AL.: Pharm. Res., 18, 1645 (2001), Davis, A., et al.: Curr. Opin. Chem. Biol., 8, 378 (2004), Wang, J., ET AL.: Anal. Chim. Acta, 601, 156 (2007),<br></p>Formula:C19H20N2O3Color and Shape:NeatMolecular weight:324.374-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide
CAS:<p>Applications 4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide is an impurity of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Formula:C15H17N3O2SColor and Shape:White To Light YellowMolecular weight:303.384-Bromo-1-ethyl-1 H -pyrazole-3-carboxylic acid methyl ester
CAS:Formula:C7H9BrN2O2Purity:96%Color and Shape:SolidMolecular weight:233.0652-Amino-5-bromo-N-cyclohexyl-N-methylbenzylamine Dihydrochloride
CAS:Controlled Product<p>Impurity Bromhexine EP Impurity D<br>Applications 2-Amino-5-bromo-N-cyclohexyl-N-methylbenzylamine (Bromhexine EP Impurity D) is an impurity of Bromhexine hydrochloride (B678600). Bromhexine hydrochloride impurity D.<br>References Uboh, C.E., et al.: J. Pharmaceut. Biomed. Anal., 9, 33 (19991),<br></p>Formula:C14H21BrN2·2ClHColor and Shape:Light YellowMolecular weight:370.16(2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications (2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile is a key intermediate for dipeptidyl peptidase IV inhibitor Vildagliptin (V305000).<br>References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008);<br></p>Formula:C7H9ClN2OColor and Shape:NeatMolecular weight:172.61Perphenazine-d4 (phenothiazine-1,3,7,9-d4)
CAS:Controlled Product<p>Applications Perphenazine-d4 (phenothiazine-1,3,7,9-d4) (CAS# 155593-75-2) is a useful isotopically labeled research compound.<br></p>Formula:C21D4H22ClN3OSColor and Shape:NeatMolecular weight:407.993,4-Dihydro Naratriptan Oxalate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 3,4-Dihydro Naratriptan Oxalate is the basic form of 3,4-Dihydro Naratriptan(D449205); it is an impurity of Naratriptan (N378730), It is a triptan drug and is used for the treatment of migraine headaches.<br>References Dulery, B.D., et al.: J. Pharm. Biomed. Anal., 15, 1009 (1997), Havanka, H., et al.: Clin. Ther., 22, 970 (2000),<br></p>Formula:C17H23N3O2S·C2H2O4Color and Shape:White To Light YellowMolecular weight:333.45 + 90.03Quinoline Yellow (Technical Grade)
CAS:<p>Stability Hygroscopic<br>Applications Quinoline yellow, is a yellow powder used in lipstick, lotion, soap, shampoo, bubble bath, ingested drugs, and applied drugs applications.<br></p>Formula:C18H9NNa2O8S2Color and Shape:NeatMolecular weight:477.381-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
CAS:<p>Applications Used in the preparation of Mirtazapine (M365000) impurities.<br></p>Formula:C17H18N4Color and Shape:Light Yellow To BrownMolecular weight:278.35Levomepromazine EP Impurity D
Controlled ProductFormula:C32H33N3O2S2Color and Shape:NeatMolecular weight:555.8Sibutramine, Hydrochloride Monohydrate
CAS:Controlled ProductFormula:C17H26ClN·ClH·H2OColor and Shape:Off White SolidMolecular weight:334.322-Amino-4-thiazoleacetic Acid
CAS:Controlled ProductFormula:C5H6N2O2SColor and Shape:NeatMolecular weight:158.186-chloro-2-(4-methylphenyl)quinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:297.739990234375Fingolimod
CAS:Controlled Product<p>Applications Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.<br>References Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004),<br></p>Formula:C19H33NO2Color and Shape:NeatMolecular weight:307.47N-Benzyl Hydroxymedetomidine
CAS:Controlled Product<p>Applications N-Benzyl Hydroxymedetomidine is an impurity of Medetomidine (M203250, HCl); an α2-adrenergic agonist, sedative, and analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996)<br></p>Formula:C20H22N2OColor and Shape:NeatMolecular weight:306.4Teneligliptin
CAS:<p>Teneligliptin (MP-513), potent DPP-4 inhibitor, IC50 ~1 nM, blocks DPP-4 in human/rat plasma and recombinant forms.</p>Formula:C22H30N6OSPurity:99.73%Color and Shape:SolidMolecular weight:426.58N-Nitrosodesipramine
CAS:Formula:C18H21N3OColor and Shape:Yellow To Dark YellowMolecular weight:295.38N,N'-Methylene Ambroxol Hydrochloride
CAS:Controlled Product<p>Impurity Ambroxol EP Impurity B Hydrochloride<br>Stability Hygroscopic<br>Applications Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).<br>References Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978); Nieder, M. et al.: HRC & CC, 9, 561 (1986); Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (2008);<br></p>Formula:C14H18Br2N2O·ClHColor and Shape:White To Off-WhiteMolecular weight:426.57N-Nitroso Desmethyl Olopatadine
Controlled ProductFormula:C20H20N2O4Color and Shape:NeatMolecular weight:352.3843-Phenoxyphenylacetonitrile
CAS:Controlled Product<p>Applications 3-PHENOXYPHENYLACETONITRILE (cas# 51632-29-2) is a useful research chemical.<br></p>Formula:C14H11NOColor and Shape:NeatMolecular weight:209.24
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