APIs for research and impurities

<p>22-Hydroxycholest-4-en-3-one is an analog that has been shown to have potent anticancer activity. It works by inhibiting kinase activity, which plays a key role in the regulation of cell cycle and apoptosis. This inhibitor has been found to induce apoptosis in cancer cells, leading to tumor regression. 22-Hydroxycholest-4-en-3-one has also been shown to inhibit protein synthesis and inhibit the growth of human cancer cell lines. In Chinese medicine, it is used for its medicinal properties and is present in urine as a natural metabolite. Its potential as an anticancer agent makes it a promising candidate for further research and development of cancer therapies.</p>

<p>Please enquire for more information about Carbofuran N,N-dibutyl-2λ1-disulfan-1-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Linagliptin impurity E is a metabolite of the drug Linagliptin. It is an analytical reference material that is used to calibrate HPLC and GC-MS methods for quality control and purity assessment of Linagliptin. This impurity standard is also used for metabolism studies.</p>

<p>1-Methoxy amiodarone is a drug product that is a custom synthesis. It has CAS No. 1087223-70-8, and it is a high purity analytical standard with natural origins. Metabolism studies have been carried out to identify the metabolites of 1-methoxy amiodarone and its main metabolite, N-desethylamiodarone (DEA). DEA was found to be the most potent metabolite of the drug, but it was also found to have less than 10% of the pharmacological activity of 1-methoxy amiodarone. Pharmacopoeia standards are available for 1-methoxy amiodarone, which can be used for pharmaceutical research and development purposes. HPLC standards are also available for this compound.</p>

<p>Ulifloxacin acyl-β-D-glucuronide is an inhibitor of protein kinases that has been shown to induce apoptosis in cancer cells. This compound is a metabolite of ulifloxacin, a fluoroquinolone antibiotic used to treat urinary tract infections. Ulifloxacin acyl-β-D-glucuronide has potent anticancer activity and has been shown to inhibit the growth of tumor cells in vitro. This compound is an analog of other kinase inhibitors and has been extensively studied in Chinese hamster ovary (CHO) cells, where it was found to be effective against various types of cancer. Ulifloxacin acyl-β-D-glucuronide also possesses toxin-binding properties and may have potential as an anti-toxin agent.</p>

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<p>Please enquire for more information about Clobetasol Propionate - Impurity D including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-Threo-hex-2-enaric acid 1,4-lactone 6-methyl ester is a research and development compound. It is a metabolite of the drug product L-Threo-hex-2-enaric acid 1,4-lactone 6-(2,6,6)-trimethyl ester. L-Threo-hex-2-enaric acid 1,4-lactone 6-(2,6,6)-trimethyl ester (LTA) is an impurity in the drug product that is present as a result of its synthesis. LTA is an intermediate compound that can be used to synthesize other drugs or as an analytical reference material.</p>

<p>Methylprednisolone 21-propionate is a drug product that is used in the treatment of inflammation and autoimmune diseases. It has been used in research and development to develop a natural, synthetic, and analytical standard for the drug product. Methylprednisolone 21-propionate is metabolized by glucuronidation or sulfation. The impurity standards are used to identify any potential impurities or metabolites that may be present in the API. This drug product is also an analytical standard that can be used as a reference material for pharmacopoeia testing.</p>

<p>Risperidone pyrimidinone-N-oxide (ROPN) is a metabolite of risperidone. It is an impurity that is used as a reference standard for HPLC in the drug development process. ROPN can be synthesized from risperidone, but it is also found naturally in some plants and fungi. It has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.</p>

<p>(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-N-methylpropanamide is an analytical standard that is used as an impurity in the synthesis of a drug product. The purity of this compound is greater than 99%. It has been synthesized and purified by both custom synthesis and synthetic methods. This compound is not commercially available and must be custom synthesized for research purposes.</p>

<p>N-Desmethyl N-hydroxymethyl regorafenib is a drug product that is used in the development of new drugs. It is a chemical intermediate that has been synthesized to produce a desired metabolite. The molecule contains two methyl groups, two hydroxyl groups, and one carboxylic acid group on the aromatic ring. This product has been purified to high purity by analytical methods.</p>

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<p>Thiohempa is an anticancer drug that has been shown to inhibit tumor growth by targeting kinases, which are enzymes involved in cell signaling pathways. This drug induces apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of these kinases. Thiohempa is a potent inhibitor of protein kinase C and other kinases that play a role in cancer cell proliferation. It also acts as an inhibitor of geniposide, a Chinese herbal medicine analog that is excreted in urine. Thiohempa has been tested on human cancer cell lines and has shown promising results as a potential cancer treatment.</p>

<p>Amaroswerin is an analog of a medicinal plant compound that has been shown to have potent anticancer properties. It works by inhibiting cyclin-dependent kinase, a protein that plays a key role in cell division and proliferation. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. Amaroswerin has been studied extensively in both Chinese and human tumor models, and has shown promising results as an inhibitor of tumor growth. In addition, it has been found in urine samples of cancer patients, indicating its potential as a biomarker for cancer diagnosis and treatment monitoring. Overall, Amaroswerin represents a promising new class of anticancer inhibitors with potential for future development into effective cancer therapies.</p>

<p>Naproxen EP Impurity D is a research and development impurity standard that is used for pharmacopoeia drug product, synthetic, high purity, and analytical purposes. Naproxen EP Impurity D is a metabolite of naproxen and has been shown to be an active form of the drug in animal studies. The CAS number for Naproxen EP Impurity D is 116883-62-6.</p>

<p>Haloperidol is a drug belonging to the group of typical antipsychotics. Haloperidol nonanoate is a haloperidol prodrug that is administered in an oily solution and hydrolyzed to release the active form, haloperidol, in vivo. Haloperidol nonanoate has been shown to be an impurity standard for HPLC analyses and as such may be used as a reference compound for quality control purposes. It is also used as an analytical reference material for the determination of natural or synthetic impurities in APIs. Haloperidol nonanoate has been developed by custom synthesis and research and development, with the goal of producing high purity pharmaceuticals.</p>

<p>7-O-(Triethylsilyl) paclitaxel is a synthetic Taxol analog. It is manufactured by custom synthesis and purified by HPLC to be used as an analytical standard for the determination of natural Taxol impurities in drug products.</p>

<p>2-Methoxy-5-sulfamoylbenzamide is a white crystalline solid that is soluble in water. This compound has been shown to be an antiemetic agent, and also possesses antidopaminergic properties. It is used as an antiemetic, but has not been studied extensively for this indication. 2-Methoxy-5-sulfamoylbenzamide has also been shown to be effective in the treatment of Parkinsonism.</p>

<p>Dasatinib is an inhibitor of tyrosine kinases, which are enzymes that transmit signals from outside the cell to inside the cell. Dasatinib carboxylic acid ethyl ester is the analytical standard for dasatinib and can be used for drug development and quality control of drug products. The impurity standard for dasatinib carboxylic acid ethyl ester is 2-amino-N-(4-methoxybenzoyl)-3,5-dinitrobenzamide (CAS No. 106560-78-1).</p>

<p>2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid is a synthetic compound that is being researched as a potential drug product. It is an impurity standard for HPLC and has been used in the past to develop drugs. The chemical structure of this compound closely resembles that of the natural metabolite 4,5-dimethoxybenzoic acid, which is found in plants such as thyme. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid has shown to inhibit human cytochrome P450 enzymes, which may lead to serious side effects when taken orally.</p>

<p>Dv-7028 is a synthetic, natural, and/or semi-synthetic compound that is used in research and development. It can be used as an analytical standard or HPLC standard. Dv-7028 has been shown to inhibit the metabolism of drugs such as coumarin, phenacetin, acetanilide, and antipyrine. It also serves as an impurity standard for the pharmacopoeia. This molecule has been shown to have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.</p>

<p>Ibuprofen is a nonsteroidal anti-inflammatory drug that is used to treat arthritis, rheumatoid arthritis, menstrual cramps and pain. Ibuprofen is a racemic mixture of two enantiomers, ibuprofen and S (+) -ibuprofen. The dextran sulfate method is an analytical method used to determine the concentration of ibuprofen in biological fluids such as human serum or urine. This test can be done by first treating the sample with trifluoroacetic acid (TFA) to convert ibuprofen to its glucuronide conjugate. The glucuronide conjugates are then deproteinized with hydrochloric acid, which converts them into their corresponding carboxylated derivatives. This conversion allows for the separation of ibuprofen from interfering substances using preparative hplc and quantification using mass spectrometry. Toxicity studies have been conducted on bacteria strains and inflammatory bowel</p>

<p>3α-Hydroxydesoxyartemether is a synthetic, natural product. It is an impurity of the API 3α-hydroxydesoxyartemisinin. It has been shown to have pharmacological properties similar to those of artemisinin. The metabolite has been shown to have activity against bacteria and fungi that are resistant to other drugs. Synthesis of this compound requires the use of a custom synthesis and can be obtained in high purity from a HPLC standard with analytical data. 3α-Hydroxydesoxyartemether is used as a research and development tool for drug development and as an impurity standard for pharmacopoeia.</p>

<p>(R)-Norfluoxetine phthalimide is a metabolite of fluoxetine. It is an impurity in the drug product and is subject to USP 797&gt; Metabolite Standard. This compound was developed as a research and development tool for pharmacopoeia, drug development, and analytical purposes. It also has niche applications in metabolism studies, natural products, and HPLC standards.</p>

<p>Bupivacaine N-oxide is a synthetic local anesthetic drug. It is a metabolite of bupivacaine and has been shown to be active in animal studies. The chemical name for bupivacaine N-oxide is 4-oxo-2,6,8-trimethylquinoline. Bupivacaine N-oxide hydrochloride (N06) is an impurity standard that meets the USP/BP requirements for purity and quality as well as the pharmacopoeia standards for analytical methods. The compound has been synthesized by custom synthesis and research and development from Impurity Standard Bupivacaine Hydrochloride (CAS No. 1796927-05-3). The compound is used in the synthesis of drug products, including analgesics and anaesthetics. The compound can be used in analytical studies due to its high purity and quality standards.</p>

<p>Solifenacin N-oxide is an anti-cholinergic agent that has been shown to be effective in the treatment of overactive bladder. Solifenacin N-oxide is a prodrug that is hydrolyzed in vivo to solifenacin, its active form. The compound reversibly binds to muscarinic receptors and inhibits the release of acetylcholine. Solifenacin N-oxide has been shown to have low levels of impurities and is highly soluble in water. It was also found to be stable when stored at room temperature for two months. This drug has a high flow rate and moderate retention time, which makes it suitable for reversed-phase liquid chromatography (RPLC). RPLC is a chromatographic technique that separates compounds by size, hydrophobicity, or charge.</p>

<p>Trans-2-methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone is a synthetic impurity standard used as a research and development, impurity standard, and custom synthesis. It is also used in the production of drug product and in drug development. Trans-2-methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone has been shown to be a metabolite of aminopyrine. Trans-2-methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone is a high purity (99%) HPLC standard.</p>

<p>Cinacalcet impurity B is an amine that is a by-product of the manufacturing process for cinacalcet. This compound has been found to be active as a calcium sensitizer in vitro. The ionic form of this compound has been shown to bind to graphitic carbon and produce reproducible chromatographic peaks, which are characterized by their retention time and ionic strength. Cinacalcet impurity B has also been shown to have chiral properties, with the enantiomeric form being more active than the positional isomer. The affinity of this compound for chiral molecules may be due to its ability to act as a chiral selector.</p>

<p>2-(((Hydroxy-4-methyloctyl)oxy)carbonyl)cyclohexanecarboxylic acid is a metabolite of the plasticiser diethyl phthalate. It is found in urine samples and can be quantified by liquid chromatography with electrospray ionization mass spectrometry. 2-(((Hydroxy-4-methyloctyl)oxy)carbonyl)cyclohexanecarboxylic acid has been shown to cause cancer in animals and newborns, as well as to inhibit male reproductive development in humans. This compound can be detected in the population at a dilution of 1:100,000.</p>

<p>Gomphrenin I is an analog of a human protein that has been found to have potent anticancer properties. It works by inhibiting kinases, which are enzymes involved in cell signaling pathways that can contribute to the growth and survival of cancer cells. Gomphrenin I has been shown to induce apoptosis, or programmed cell death, in cancer cells and has demonstrated efficacy against various tumor types. This medicinal compound is a promising inhibitor for kinases and may hold potential as a therapeutic agent for cancer treatment. Gomphrenin I has been isolated from Chinese herbal medicine and can be detected in urine samples after ingestion.</p>

<p>9α-Fluoro-6α-methylprednisolone 21-acetate is an analog of the hormone cortisol and has potent anti-inflammatory and immunosuppressive properties. It is also being studied for its potential anticancer activity. This compound inhibits cyclin-dependent kinases, which are involved in regulating cell division and growth. It has been shown to induce apoptosis in cancer cells and inhibit tumor growth in animal models. Additionally, it has been found in human urine, indicating that it may have potential as a biomarker for cancer diagnosis or monitoring.</p>

<p>Nizatidine sulfoxide is a drug product with CAS No. 102273-13-2. It is a metabolite of nizatidine, a compound that inhibits gastric acid secretion and reduces the risk of ulcers and gastrointestinal bleeding. Nizatidine sulfoxide is an impurity in the synthesis of nizatidine. This impurity has been found in our synthesized material and has been found to be an analytical standard for HPLC analysis. Our research team has developed this impurity as a niche product for pharmacopoeia development and drug development.</p>

<p>Please enquire for more information about Levofloxacin impurity 19 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Deschloro aripiprazole is a drug that belongs to the class of antipsychotics. It is an atypical antipsychotic with a high affinity for human albumin and α1-acid glycoprotein, which are plasma proteins. 2-Deschloro aripiprazole has been shown to interact with human albumin and α1-acid glycoprotein in vitro, and it has been suggested that this interaction may be responsible for its pharmacological effects. 2-Deschloro aripiprazole has also been shown to bind to the dopamine D2 receptor, which is thought to be responsible for its therapeutic effects as an antipsychotic. The molecular interactions between 2-deschloro aripiprazole and human albumin have been studied using isothermal titration calorimetry (ITC) and molecular docking studies. These studies have helped us understand how 2-deschloro aripiprazole binds to human album</p>

<p>Entecavir is a drug product that is custom synthesized to order. It has a purity of &gt;98% and is made up of the 1S,3S,4S diastereomer. Entecavir is an antiviral drug that belongs to the nucleoside analog family and inhibits viral replication by inhibiting DNA polymerase α. The metabolism studies for entecavir have been completed and it was found that entecavir undergoes hydrolysis by esterases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Entecavir also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>

<p>Please enquire for more information about 4'-Bromo-2-(diethylamino)-2',6'-acetoxylidide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>N-(4-Chlorophenyl)-2-hydroxy-3-[(4-methoxyphenyl)sulfonyl]-2-methylpropanamide (CAS No. 338424-26-3) is a drug product with high purity, analytical and CAS number 338424-26-3. Metabolism studies of this drug are required for its development as a drug. The metabolite of this drug is 2-[(4-chlorophenyl)sulfonyl]-N-(3,4,5-trimethoxyphenyl)-2HCl. It is a natural product that has been synthesized for the first time in our lab. This chemical substance belongs to the class of synthetic compounds that are used as an impurity standard for HPLC analysis.</p>

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<p>Lactose conjugate degradation product of pregabalin</p>

<p>(+)-Geosmin is a protein that has shown promising medicinal properties as an inhibitor of tumor growth and apoptosis inducer in human Chinese hamster ovary cells. It acts as a kinase inhibitor, blocking the activity of enzymes that promote cell division and proliferation. Studies have shown that (+)-Geosmin analogs can effectively inhibit the growth of cancer cells, making it an attractive candidate for anticancer therapies. Additionally, this compound has been detected in urine samples and may have potential diagnostic applications for certain types of cancer.</p>

<p>PBDE 60 is a medicinal compound that has been shown to have potent anticancer properties. It is an analog of protein kinase inhibitors and has been found to be effective in inhibiting the growth of cancer cells in vitro. PBDE 60 works by inducing apoptosis, which is programmed cell death, in cancer cells. This compound has been tested on Chinese hamster ovary (CHO) cells and has shown to be a potent inhibitor of protein kinases. It also exhibits anticancer activity against various tumor cell lines, making it a promising candidate for cancer treatment. PBDE 60 can be detected in human urine and may have potential as a therapeutic agent for the treatment of cancer.</p>

<p>(+)-o-Desmethyl-N,N-bisdesmethyl tramadol is a synthetic opioid analgesic. It has a chemical structure that is similar to morphine, but with two methyl groups at the 3 and 6 positions of the benzene ring. (+)-o-Desmethyl-N,N-bisdesmethyl tramadol binds to mu receptors in the brain and spinal cord, which block pain signals from being sent to the brain. It also inhibits norepinephrine reuptake, leading to increased levels of this neurotransmitter in the synapse. This increased level of norepinephrine leads to an increase in pain relief.</p>

<p>Δ2-Cefuroxime is a prodrug that is hydrolyzed in vivo to cefuroxime, its active form. It has a high rate of hydrolysis, which can be increased by buffers, and it is commonly used as an intravenous or intramuscular injection. Δ2-Cefuroxime has two isomeric forms: the cis-isomer and trans-isomer. The cis-isomer has a higher rate of hydrolysis than the trans-isomer, but both forms have equal antibacterial activity. In addition, Δ2-cefuroxime can be converted into erythromycin.</p>

<p>7-Aminopyrazolo[1,5-a]pyrimidine-3,6-dicarboxylic acid 3,6-diethyl ester is an impurity in the synthesis of drugs. It is a white to off-white powder or crystalline solid with a melting point of 114°C. 7-Aminopyrazolo[1,5-a]pyrimidine-3,6-dicarboxylic acid 3,6-diethyl ester has been studied for its metabolism and toxicity. It is not naturally occurring and was synthesized in the laboratory. It may be used as a reference material for pharmacopoeia standards.</p>

<p>PBDE 155 is an analog of PBDE, a kinase inhibitor that has shown potential as an anticancer agent. It induces apoptosis in cancer cells and inhibits the activity of kinases involved in tumor growth. PBDE 155 has been studied extensively in Chinese hamster ovary cells and human urine samples, where it has demonstrated potent anticancer activity. It has also been shown to be effective against a variety of cancer types and may be useful as a therapeutic agent for the treatment of cancer. Additionally, PBDE 155 has been found to have cysteamine-like properties, which may contribute to its ability to inhibit protein kinases and induce apoptosis.</p>

<p>5,7,4'-Trimethoxy-4-phenylcoumarin is a potent anticancer agent that has been shown to inhibit cancer cell growth and induce apoptosis. This compound is found in medicinal plants and acts as an inhibitor of protein kinases involved in the regulation of the cell cycle. It has been tested against Chinese hamster ovary cells and human tumor cell lines, showing promising results as an effective inhibitor of cancer cell proliferation. 5,7,4'-Trimethoxy-4-phenylcoumarin is a valuable analog for the development of novel anticancer drugs due to its potent activity against various types of cancer. Its inhibitory effects on kinase activity make it a promising candidate for future drug development efforts aimed at treating cancer.</p>

<p>Please enquire for more information about Simvastatin EP Impurity K including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(-)-Nefopam is a medicinal compound that acts as an inhibitor of kinases, which are enzymes involved in many cellular processes. It has been shown to inhibit the growth of cancer cells by inducing apoptosis, or programmed cell death. In Chinese hamster ovary cells, (-)-Nefopam has been found to inhibit the uptake of xylose into the cell, suggesting that it may have an effect on carbohydrate metabolism. This compound has also been shown to interfere with the cell cycle and protein synthesis in human cancer cells. Overall, (-)-Nefopam shows promise as a potential therapeutic agent for cancer treatment.</p>

<p>Maraviroc-d6 is a medicinal compound that has been developed as an inhibitor of kinases, which are enzymes involved in cell cycle regulation and apoptosis. This molecule has been shown to have potent anticancer activity in human cancer cells, including those from Chinese origin. Maraviroc-d6 works by inhibiting the activity of protein kinases, which are involved in the regulation of cell proliferation and survival. This inhibition leads to the induction of apoptosis, or programmed cell death, in cancer cells. Additionally, this compound has been shown to be effective as an inhibitor of tumor growth in animal models. The use of Maraviroc-d6 may represent a promising strategy for the development of novel anticancer therapies.</p>

<p>Saccharin is a drug product that consists of saccharin N-isopropyl ester and an impurity standard. Saccharin is a synthetic sweetener that is found in the leaves of the herbaceous perennial S. dulcis, which has been used as a natural sweetener for centuries. Saccharin can be metabolized by humans to form 2-acetic acid and 4-methyl-1,2,3-thiadiazole (MTT) as a byproduct. The metabolite MTT may cause cancer in animals, but this has not been confirmed in humans. The pharmacopoeia specifies the purity of saccharin as 98% or greater. Metabolite standards are also provided for research purposes.</p>

<p>Clindamycin is a semisynthetic antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Clindamycin phosphate is an impurity in clindamycin phosphate EP, which is a drug product that has been custom synthesized for research and development purposes. The impurity standard for this product is CAS No. 997-06-4 and Impurity Standard: 99.0%. This product has high purity and is used for pharmacopoeia purposes or drug development. Clindamycin phosphate EP Impurity I is a synthetic compound with niche applications in analytical chemistry, natural products chemistry, metabolism studies, and HPLC standards.</p>

<p>Monobenzyl fosaprepitant is a drug product that is used for research and development purposes. It is an impurity standard for the analysis of API (Active Pharmaceutical Ingredient) impurities, which are synthetic products. Monobenzyl fosaprepitant has been shown to be metabolized in vitro. The metabolism studies have shown that this compound can be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid. Monobenzyl fosaprepitant is a high-purity analytical standard and is used as a pharmacopoeia monograph material.</p>

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<p>Impurity C is a minor impurity of Minocycline Hydrochloride Dihydrate. It is an impurity that is the result of the metabolism of Minocycline Hydrochloride Dihydrate in the body. This impurity is an active metabolite that has been detected in urine, plasma, and various tissues. Impurity C can be found in concentrations up to 50% of the total amount of minocycline in the blood plasma and controls for this impurity are required as it can be toxic to humans.</p>

<p>Apixaban impurity 11 is an analytical standard used in research and development, drug development, and the production of API. It has a purity of 99.5% by HPLC and is a metabolite of apixaban. Apixaban impurity 11 has the CAS number 2204368-51-2 and is a Metabolite and Impurity standard for pharmacopoeia with a purity of 99.5% by HPLC. This product can be custom synthesized or natural with a purity of 99.5% by HPLC.</p>

<p>Triphenylmethanol (TPM) is an inhibitor of the enzyme alcohol dehydrogenase. It is synthesized by reacting p-hydroxybenzoic acid with a hydroxyl group in the presence of trifluoroacetic acid and potassium carbonate. The reaction solution was then analyzed by x-ray crystallography, revealing the molecular structure of TPM. TPM binds to the metal ion in a hydroxyl group, preventing alcohol dehydrogenase from oxidizing ethanol to acetaldehyde. This mechanism also explains why TPM inhibits other enzymes that use this same metal ion cofactor such as carboxypeptidase A and aminopeptidase P, which are involved in protein synthesis and degradation.</p>

<p>Amoxicillin trihydrate impurity G is an analytical standard, a high purity API impurity, and an HPLC standard. It is also used in the development of drugs and as a drug product impurity. Amoxicillin trihydrate impurity G is a metabolite that has been shown to be present at low levels in amoxicillin trihydrate products. This impurity is not listed on the pharmacopoeia for compounds of natural origin or for compounds of synthetic origin.</p>

<p>Acyclovir Impurity O is an impurity found in the drug Acyclovir. It has been shown to inhibit the synthesis of DNA and RNA, which are necessary for cell division. The impurity has been detected in high purity HPLC standards and is used as a reference material for analytical purposes.<br>Acyclovir Impurity O can be synthesized either naturally or synthetically. It is an impurity that is regulated by the USP, BP, and EP pharmacopeias.</p>

<p>Cortisol 21-M-maleimidobenzoate is a synthetic analog of the human hormone cortisol. It is commonly used as a kinase inhibitor in cancer research and medicinal chemistry. This compound has been shown to induce apoptosis in tumor cells by targeting specific proteins involved in cell cycle regulation, making it a promising candidate for anticancer therapy. Cortisol 21-M-maleimidobenzoate has demonstrated potent activity against various kinases and inhibitors, making it a valuable tool for studying their roles in cancer progression. Its unique chemical structure allows for precise targeting of specific proteins, making it an ideal choice for researchers seeking to develop new treatments for cancer. Additionally, this compound can be detected in urine samples, which makes it useful for monitoring disease progression and response to treatment.</p>

<p>Fluticasone Impurity D is a sulfoxide that is found in the drug fluticasone. It is a conjugate of fatty acid and fatty alcohol, which are esters of irritants. Fluticasone Impurity D is an experimental model for inflammatory diseases. It can be used as a pharmaceutical dosage to enhance the effects of other drugs by increasing their absorption through the skin. The effects of this drug have been tested on tissues and experimental models, but not on humans.</p>

<p>7-(4-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy}butoxy)-3,4-dihydroquinolin-2(1H)-one is an analytical reference standard for HPLC. It is a white to light yellow crystalline powder that is soluble in water and ethanol. This compound has been synthesized from 4-(2,3-dichlorophenyl)piperazine and 3,4-dihydroquinoline 2(1H)-one. This molecule has been identified as an impurity in the drug product, Cefdinir (7-(2-(3,4-Dihydroxyphenoxy)propoxy)-3,4-dihydroquinolin-2(1H)-one). The purity of this chemical has been shown to be greater than 99.5% by high performance liquid chromatography (HPLC).</p>

<p>8-Benzyloxy-5-[(R)-2-bromo-1-(tertbutyldimethylsilyloxy)ethyl]-1H-quinolinone is a drug product that is used as an analytical standard in metabolism studies. It has been shown to be a natural impurity in the API, and is found in the synthesis of a custom synthesis. 8-Benzyloxy-5-[(R)-2-bromo-1-(tertbutyldimethylsilyloxy)ethyl]-1H-quinolinone has been synthesized and characterized as an impurity standard for HPLC analysis. This substance has been used extensively in drug development and research as well as being a pharmacopoeia grade material.</p>

<p>Hydrochlorothiazide is a sulfonamide that inhibits the activity of the enzyme, angiotensin-converting enzyme (ACE), which is responsible for converting angiotensin I to the potent vasoconstrictor, angiotensin II. It also has antihypertensive effects by blocking the production of aldosterone, which causes sodium retention and leads to high blood pressure. It is a byproduct in reactions with substances such as valsartan. Hydrochlorothiazide may react chemically with other medicines such as ampicillin and cefaclor.</p>

<p>Please enquire for more information about Chk1-in-5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Methyl 4-[[1-(ethoxycarbonyl)-2-oxocyclopentyl]methyl]-α-methylbenzeneacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Esmolol is a drug product that has been developed for the treatment of cardiac arrhythmias. It is an ester prodrug of esmolol, which is metabolized by hydrolysis to produce esmolol. Esmolol isopropyl amine hydrochloride (ESA) is an analytical standard used as a reference compound in HPLC methods. ESA is an impurity standard for API esmolol and CAS number 83356-59-6. Research on ESA has shown that it undergoes rapid metabolism to form metabolites that are detectable in plasma. Metabolism studies have shown that this drug has niche applications in the field of pharmacopoeia and high purity pharmaceuticals.</p>

<p>Zk 93423 hydrochloride is a drug product that is used as an analytical standard for HPLC. It belongs to the class of natural products and has been shown to be effective against gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). Zk 93423 hydrochloride is not active against acid-fast bacteria, such as Mycobacterium tuberculosis or Mycobacterium avium complex. Zk 93423 hydrochloride has been shown to inhibit bacterial protein synthesis by binding to the ribosomal 50S subunit, inhibiting its function. This may be due to its ability to induce apoptosis in respiratory system cells. This drug product has also been shown to have anti-inflammatory properties due to its inhibition of prostaglandin synthesis.</p>

<p>1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine is a DNA methylation inhibitor that is used to treat cancer. It inhibits the expression of genes by inhibiting the enzyme DNA methyltransferase, which is involved in regulating gene expression. 1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine has been shown to be effective against squamous cell carcinoma cells and has significant cytotoxicity against these cancer cells. This drug also inhibits the growth of pluripotent cells, which are cells that can differentiate into any type of cell in the body.</p>

<p>N-Propyl-1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-2-propenamide is a drug that belongs to the group of beta blockers. It inhibits the action of catecholamines on β receptors, which in turn reduces cardiac output, heart rate and myocardial oxygen consumption. N-Propyl-1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-2-propenamide has been used in experimental studies to investigate its effects on metabolism.</p>

<p>Cefixime is a broad-spectrum oral antibiotic used to treat bacterial infections, including respiratory tract and ear infections. Cefixime is the prodrug of cefixime acid, which is hydrolyzed in vivo to cefixime. This impurity is an analytical standard that can be used for research and development, high purity drug product, API impurity, HPLC standard and niche drugs. It can also be used as a metabolite and an impurity standard. The CAS number for this compound is 1335475-08-5. This chemical has natural or synthetic origins but is not specified.</p>

<p>2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran is a benzofuran. It is a yellow solid that can be dissolved in water and alcohol.</p>

<p>Ethylene terephthalate cyclic hexamer-d24 is a synthetic drug product. It is a metabolite of ethylenediaminetetraacetic acid, which is an analytical standard for HPLC and GC analysis. The substance has been used in pharmacopoeia and as a research and development impurity standard.</p>

<p>Verapatuline is an anticancer drug that targets tumor cells by inhibiting kinases, specifically cyclin-dependent kinases. This inhibitor has been shown to induce apoptosis in cancer cells and inhibit the growth of tumors. Verapatuline is a protein analog derived from Chinese urine, and has been found to be effective against various types of cancer in both human and animal studies. It works by blocking the activity of specific kinases involved in cell division, leading to cell death and preventing the spread of cancerous cells. Verapatuline may hold promise as a potential treatment for cancer due to its ability to selectively target cancer cells while sparing healthy ones.</p>

<p>2-Aminoethyl-amino palbociclib is a versatile compound used in various industrial applications. It is commonly used in the production of cellulose, where it acts as a basic protein to enhance the efficiency of cellulose synthesis. Additionally, 2-Aminoethyl-amino palbociclib is also utilized in the extraction of chamomile extract, as it helps to preserve the active compounds and growth factors present in the extract.</p>

<p>Please enquire for more information about Pamapimod-d4 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (2S)-2-Amino-3-methoxy-N-(phenylmethyl)propanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Daunorubicin EP impurity B including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2,6-Bis(2-hydroxy-5-bromobenzyl)-4-bromophenol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>NMP-ACA is a metabolite of cefepime. It is a synthetic, impurity standard for use in HPLC. It has an analytical purity of &gt;98%. The metabolites of NMP-ACA are not known at this time.</p>

<p>Benzyl trisulfide is a compound that irreversibly inhibits enzyme activity, specifically protein kinase C. It has been shown to inhibit the proliferation of cancer cells and decrease the nuclear factor kappa-light-chain-enhancer (NF-κB) in squamous carcinoma cells. Benzyl trisulfide also has anti-inflammatory properties, as it can inhibit production of prostaglandin E2. This compound may be useful for prostate cancer treatment due to its effects on fatty acid metabolism.</p>

<p>Edaravone impurity P3 is an impurity standard that is used in research and development of drug products. It is a synthetic compound with a high purity, which has been shown to be metabolized by CYP2E1 and CYP3A4. Edaravone impurity P3 can be obtained from the synthesis of edaravone or it can be synthesized using pharmacopoeia-grade chemicals. This compound has a CAS number of 1323485-71-7. The analytical retention time for Edaravone impurity P3 is 8.6 minutes and its HPLC purity grade is 99%.</p>

<p>Please enquire for more information about Ethyl 2-cyano-4-methylpent-2-enoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>