Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
Mostrar 10 subcategorías más
Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
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PHA-767491
CAS:<p>PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.</p>Fórmula:C12H11N3OPureza:99.49% - >99.99%Forma y color:SolidPeso molecular:213.24Sarecycline free base
CAS:<p>Sarecycline free base (P005672) is a tetracycline-derived, narrow-spectrum antibiotic.</p>Fórmula:C24H29N3O8Pureza:98%Forma y color:SolidPeso molecular:487.5Seliciclib
CAS:<p>Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.</p>Fórmula:C19H26N6OPureza:97.15% - 99.89%Forma y color:White To Off-White SolidPeso molecular:354.45InhA-IN-2
CAS:<p>N-[3-(Aminomethyl)phenyl]-5-chloro-3-methyl-benzo[b]thiophene-2-sulfonamide inhibits InhA without KatG activation.</p>Fórmula:C16H15ClN2O2S2Pureza:98.4%Forma y color:SolidPeso molecular:366.89Protein kinase inhibitor 6
CAS:<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Fórmula:C13H9FN2SPureza:98.01%Forma y color:SolidPeso molecular:244.29R-IMPP
CAS:<p>R-IMPP is an inhibitor of PCSK9 translation.</p>Fórmula:C24H27N3O2Pureza:99.47% - 99.85%Forma y color:SolidPeso molecular:389.496-Mercaptopurine hydrate
CAS:<p>6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.</p>Fórmula:C5H6N4OSPureza:97.54% - 99.14%Forma y color:Light Yellow Crystalline PowderPeso molecular:170.19Mogroside I E1
CAS:<p>Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.</p>Fórmula:C36H62O9Pureza:98.62% - 99.71%Forma y color:SolidPeso molecular:638.87TH5487
CAS:<p>TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)</p>Fórmula:C19H18BrIN4O2Pureza:98.38% - 98.73%Forma y color:SolidPeso molecular:541.18Ro3280
CAS:<p>Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).</p>Fórmula:C27H35F2N7O3Pureza:97.1% - >99.99%Forma y color:SolidPeso molecular:543.61360A
CAS:<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Fórmula:C27H23N5O2Pureza:98.68%Forma y color:SolidPeso molecular:449.5LIMK-IN-22j
CAS:<p>LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.</p>Fórmula:C20H21BrN8Pureza:99.165%Forma y color:SolidPeso molecular:453.34BI-847325
CAS:<p>BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.</p>Fórmula:C29H28N4O2Pureza:97.13% - 97.54%Forma y color:SolidPeso molecular:464.56BS194
CAS:<p>BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.</p>Fórmula:C20H27N5O3Pureza:99.85%Forma y color:SolidPeso molecular:385.46CWHM-12
CAS:<p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>Fórmula:C26H32BrN5O6Pureza:98.05% - 99.83%Forma y color:SolidPeso molecular:590.47CRT0066854
CAS:<p>CRT-0066854 is a PKCι and PKCζ inhibitor. CRT0066854 was able to restore polarized morphogenesis in the dysplastic H-Ras spheroids.</p>Fórmula:C24H25N5SForma y color:SolidPeso molecular:415.55CCG-222740
CAS:<p>CCG-222740 is an inhibitor of Rho/MRTF pathway</p>Fórmula:C23H19ClF2N2O3Pureza:98.76%Forma y color:SolidPeso molecular:444.86Ganciclovir sodium
CAS:<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Fórmula:C9H13N5NaO4Pureza:99.93%Forma y color:SolidPeso molecular:278.22Aplidine
CAS:<p>Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM).</p>Fórmula:C57H87N7O15Pureza:99.86%Forma y color:SolidPeso molecular:1110.34Aurora kinase inhibitor-2
CAS:<p>Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).</p>Fórmula:C23H20N4O3Pureza:98.66%Forma y color:SolidPeso molecular:400.43Activated Protein C (390-404), human acetate
<p>Activated Protein C (390-404), human acetate (Activated Protein C ) inhibits APC anticoagulant activity.</p>Fórmula:C93H134N22O25Pureza:99.92%Forma y color:SolidPeso molecular:1960.19Clevudine
CAS:<p>Clevudine (Levovir) fights HBV, blocks viral DNA synthesis, and has a long half-life reducing relapse risk after treatment.</p>Fórmula:C10H13FN2O5Pureza:99.88% - 99.97%Forma y color:SolidPeso molecular:260.22CID755673
CAS:<p>CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.</p>Fórmula:C12H11NO3Pureza:97.68% - 99.84%Forma y color:SolidPeso molecular:217.22MC180295
CAS:<p>MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.</p>Fórmula:C17H18N4O3SPureza:99.84%Forma y color:SolidPeso molecular:358.41Favipiravir
CAS:<p>Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.</p>Fórmula:C5H4FN3O2Pureza:97.32% - 99.90%Forma y color:SolidPeso molecular:157.1Cyclo(-RGDfK)
CAS:<p>Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.</p>Fórmula:C27H41N9O7Pureza:95.29% - >99.99%Forma y color:SolidPeso molecular:603.67AZ3146
CAS:<p>AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.</p>Fórmula:C24H32N6O3Pureza:97.84% - >99.99%Forma y color:SolidPeso molecular:452.55Metoprine
CAS:<p>Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.</p>Fórmula:C11H10Cl2N4Pureza:98.42%Forma y color:SolidPeso molecular:269.13CID44216842
CAS:<p>CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.</p>Fórmula:C22H20BrN3O3SPureza:99.66%Forma y color:SolidPeso molecular:486.38SNS-314 Mesylate
CAS:<p>SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.</p>Fórmula:C18H15ClN6OS2·CH4O3SPureza:99.44% - 99.92%Forma y color:SolidPeso molecular:527.04DHFR-IN-3
CAS:<p>DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.</p>Fórmula:C8H7BrN4Pureza:99.521% - 99.65%Forma y color:SolidPeso molecular:239.07NSAH
CAS:<p>NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-</p>Fórmula:C18H14N2O3Pureza:99.27%Forma y color:SolidPeso molecular:306.32M2N12
CAS:<p>M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.</p>Fórmula:C20H16ClN5O2Pureza:98.01%Forma y color:SolidPeso molecular:393.83HAMNO
CAS:<p>HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).</p>Fórmula:C17H13NO2Pureza:99.96%Forma y color:SolidPeso molecular:263.29TH287
CAS:<p>TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.</p>Fórmula:C11H10Cl2N4Pureza:97.73% - 99%Forma y color:SolidPeso molecular:269.136-AZATHYMINE
CAS:<p>6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.</p>Fórmula:C4H5N3O2Pureza:99.47%Forma y color:SolidPeso molecular:127.13-Methylcytidine
CAS:<p>3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.</p>Fórmula:C10H15N3O5Pureza:99.52%Forma y color:SolidPeso molecular:257.24IMT1B
CAS:<p>IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.</p>Fórmula:C24H21ClFNO6Pureza:98.26% - 99.83%Forma y color:SolidPeso molecular:473.88Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Fórmula:C18H16O8Pureza:99.50% - 99.85%Forma y color:SolidPeso molecular:360.31(1E)-CFI-400437 dihydrochloride
CAS:<p>(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.</p>Fórmula:C29H30Cl2N6O2Pureza:97.08%Forma y color:SolidPeso molecular:565.5Ganciclovir hydrate
CAS:<p>Ganciclovir hydrate: oral anti-cytomegalovirus; inhibits HSV 1/2, CMV, adenoviruses, FHV-1; brain-penetrating.</p>Fórmula:C9H15N5O5Forma y color:SolidPeso molecular:273.249TH-257
CAS:<p>TH-257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM).</p>Fórmula:C24H26N2O3SPureza:98.23%Forma y color:SolidPeso molecular:422.54SR18662
<p>SR18662, improved ML264 derivative, inhibits KLF5 at 4.4 nM IC50; curbs colorectal cancer cell growth and triggers apoptosis.</p>Fórmula:C16H19Cl2N3O4SPureza:98.97% - 99.2%Forma y color:SolidPeso molecular:420.31CRT0044876
CAS:<p>CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.</p>Fórmula:C9H6N2O4Pureza:98.27% - 98.98%Forma y color:Brown PowderPeso molecular:206.15EHop-016
CAS:<p>EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.</p>Fórmula:C25H30N6OPureza:98.99% - >99.99%Forma y color:SolidPeso molecular:430.555-Fluoroorotic acid
CAS:<p>5-Fluoroorotic acid is an inhibitor of thymidylate synthase.</p>Fórmula:C5H3FN2O4Pureza:99.7% - >99.99%Forma y color:White To Pale Yellow PowderPeso molecular:174.09RI-2
CAS:<p>RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.</p>Fórmula:C21H18Cl2N2O4Pureza:99.63% - 99.86%Forma y color:SolidPeso molecular:433.28Quarfloxin
CAS:<p>Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.</p>Fórmula:C35H33FN6O3Pureza:99.77%Forma y color:SolidPeso molecular:604.67AS2863619
CAS:<p>AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.</p>Fórmula:C16H14Cl2N8OPureza:>99.99%Forma y color:SolidPeso molecular:405.242'-Fluoro-2'-Deoxyadenosine
CAS:<p>2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).</p>Fórmula:C10H12FN5O3Pureza:99.95%Forma y color:SolidPeso molecular:269.23BRD9876
CAS:<p>BRD9876 is a selective inhibitor of MM1S growth.</p>Fórmula:C16H14N2Pureza:97.81%Forma y color:SolidPeso molecular:234.3Ro5-3335
CAS:<p>Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.</p>Fórmula:C13H10ClN3OPureza:99.42% - 99.87%Forma y color:SolidPeso molecular:259.69XL228
CAS:<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Fórmula:C22H31N9OPureza:99.07%Forma y color:SolidPeso molecular:437.54Tozasertib
CAS:<p>Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).</p>Fórmula:C23H28N8OSPureza:99.99%Forma y color:SolidPeso molecular:464.59APY29
CAS:<p>APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.</p>Fórmula:C17H16N8Pureza:96.51% - 98.46%Forma y color:SolidPeso molecular:332.36SAR-020106
CAS:<p>SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.</p>Fórmula:C19H19ClN6OPureza:97.78%Forma y color:SolidPeso molecular:382.85CID-797718
CAS:<p>CID-797718 is a protein kinase D1 (PKD1) inhibitor.</p>Fórmula:C12H11NO3Pureza:98.91% - 99.21%Forma y color:SolidPeso molecular:217.22Tipiracil hydrochloride
CAS:<p>Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).</p>Fórmula:C9H12Cl2N4O2Pureza:98.13% - ≥95%Forma y color:SolidPeso molecular:279.12Lurbinectedin
CAS:<p>Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.</p>Fórmula:C41H44N4O10SPureza:98.11%Forma y color:SolidPeso molecular:784.87THZ2
CAS:<p>THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).</p>Fórmula:C31H28ClN7O2Pureza:98.28%Forma y color:SolidPeso molecular:566.05Voruciclib
CAS:<p>Voruciclib: oral, selective CDK inhibitor (Ki: 0.626-9.1 nM), reduces MCL-1, targets CDK9 in diffuse large B-cell lymphoma.</p>Fórmula:C22H19ClF3NO5Pureza:99.89%Forma y color:SolidPeso molecular:469.84Pyrintegrin
CAS:<p>Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.</p>Fórmula:C23H25N5O3SPureza:99.19%Forma y color:SolidPeso molecular:451.54GSK-923295
CAS:<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Forma y color:SolidPeso molecular:592.13P18IN011
CAS:<p>P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).</p>Fórmula:C15H12N2O5SPureza:97.63%Forma y color:SolidPeso molecular:332.3310074-A4
CAS:<p>10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from</p>Fórmula:C18H14Cl2N2O3SPureza:99.06%Forma y color:SolidPeso molecular:409.29Madrasin
CAS:<p>Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.</p>Fórmula:C16H17N5O2Pureza:99.06% - 99.61%Forma y color:SolidPeso molecular:311.34BCH001
CAS:<p>BCH001 is a specific small-molecule inhibitor of PAPD5.</p>Fórmula:C20H15F3N2O5Pureza:99.06%Forma y color:SolidPeso molecular:420.34Trimethoprim sulfate
CAS:<p>Trimethoprim sulfate, a dihydrofolate reductase inhibitor, treats bacterial infections and sometimes malaria; may depress hematopoiesis.</p>Fórmula:C28H38N8O10SForma y color:SolidPeso molecular:678.72Dimethylenastron
CAS:<p>Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.</p>Fórmula:C16H18N2O2SPureza:98.07%Forma y color:SolidPeso molecular:302.39SCH900776 (S-isomer)
CAS:<p>SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).</p>Fórmula:C15H18BrN7Pureza:99.88%Forma y color:SolidPeso molecular:376.25THZ531
CAS:<p>THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).</p>Fórmula:C30H32ClN7O2Pureza:97.17% - 99.86%Forma y color:SolidPeso molecular:558.07Senexin B
CAS:<p>Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).</p>Fórmula:C27H26N6OPureza:99.67%Forma y color:SolidPeso molecular:450.53RK33
CAS:<p>"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."</p>Fórmula:C23H20N6O3Pureza:99.04% - 99.72%Forma y color:SolidPeso molecular:428.44WNK463
CAS:<p>WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).</p>Fórmula:C21H24F3N7O2Pureza:>99.99% - ≥95%Forma y color:SolidPeso molecular:463.46N2-Methylguanosine
CAS:<p>N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's</p>Fórmula:C11H15N5O5Pureza:97.77%Forma y color:SolidPeso molecular:297.27BIO-1211
CAS:<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Fórmula:C36H48N6O9Pureza:99.33%Forma y color:SolidPeso molecular:708.8Levofloxacin hydrochloride
CAS:<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Fórmula:C18H21ClFN3O4Pureza:99.78% - 99.98%Forma y color:SolidPeso molecular:397.8dGTP
CAS:<p>dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and</p>Fórmula:C10H16N5O13P3Pureza:99.64%Forma y color:SolidPeso molecular:507.18Triazavirin
CAS:<p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>Fórmula:C5H7N6NaO5SPureza:99.55%Forma y color:SolidPeso molecular:286.2T-5224
CAS:<p>T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription</p>Fórmula:C29H27NO8Pureza:97.88% - 99.29%Forma y color:SolidPeso molecular:517.53KIRA6
CAS:<p>KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 μM). It can trigger an apoptotic response.</p>Fórmula:C28H25F3N6OPureza:97.91%Forma y color:SolidPeso molecular:518.53PRT4165
CAS:<p>PRT4165 (NSC600157) is a potent PRC1-mediated H2A ubiquitylation inhibitor.</p>Fórmula:C15H9NO2Pureza:98.91% - 99.6%Forma y color:SolidPeso molecular:235.24BS-181 hydrochloride
CAS:<p>BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.</p>Fórmula:C22H32N6·HClPureza:99.21%Forma y color:SolidPeso molecular:416.99CX-5461 dihydrochloride
<p>CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).</p>Fórmula:C27H29Cl2N7O2SForma y color:SolidPeso molecular:586.54Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Forma y color:SolidPeso molecular:938.712,2'-Anhydrouridine
CAS:<p>2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies.</p>Fórmula:C9H10N2O5Pureza:98.45%Forma y color:SolidPeso molecular:226.19Leukadherin-1
CAS:<p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>Fórmula:C22H15NO4S2Pureza:98.49% - 98.93%Forma y color:SolidPeso molecular:421.49GSK180736A
CAS:<p>GSK180736A: GRK2 inhibitor (IC50 0.77µM), >100x selectivity vs GRKs, weak at PKA (IC50 30µM), strong vs ROCK1 (IC50 100nM).</p>Fórmula:C19H16FN5O2Pureza:98.38% - 98.98%Forma y color:SolidPeso molecular:365.36Gadodiamide
CAS:<p>Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.</p>Fórmula:C16H26GdN5O8Pureza:99.86%Forma y color:SolidPeso molecular:573.66K858 (Racemic)
CAS:<p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>Fórmula:C13H15N3O2SPureza:>99.99%Forma y color:SolidPeso molecular:277.345-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE
CAS:<p>5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.</p>Fórmula:C8H13N3SPureza:99.03%Forma y color:SolidPeso molecular:183.27Folinic acid calcium hydrate
CAS:<p>Folinic acid (Leucovorin) calcium hydrate is a biofolic acid often used as a rescue agent with methotrexate (MTX) to reduce MTX-induced toxicity.</p>Fórmula:C20H23CaN7O8Forma y color:SolidPeso molecular:529.523Sovilnesib
CAS:<p>Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.</p>Fórmula:C26H34F2N6O4SPureza:99.57%Forma y color:SolidPeso molecular:564.65GJ103 sodium salt
CAS:<p>GJ103 sodium salt, a GJ072 analog, lowers surface tension, viscosity, and pH in aqueous solutions, aiding molecular movement.</p>Fórmula:C16H13N4NaO3SPureza:99.70% - 99.91%Forma y color:SolidPeso molecular:364.36TAK-960 dihydrochloride
<p>TAK-960 dihydrochloride: oral PLK1 inhibitor, IC50 0.8 nM; also Hinders PLK2 and PLK3 (IC50s 16.9/50.2 nM); curbs cancer cell growth.</p>Fórmula:C27H36Cl2F3N7O3Forma y color:SolidPeso molecular:634.52Spermine tetrahydrochloride
CAS:<p>Spermine tetrahydrochloride, a polyamine in all eukaryotic cells, protects DNA from free radicals.</p>Fórmula:C10H26N4·4HClPureza:99.75% - 99.82%Forma y color:SolidPeso molecular:348.189-Ethylguanine
CAS:<p>9-Ethylguanine is a model nucleobase commonly used in the studies of DNA interactions with organometallic complexes.</p>Fórmula:C7H9N5OPureza:98.6%Forma y color:SolidPeso molecular:179.18RAD51-IN-1
CAS:<p>Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.</p>Fórmula:C22H16ClN3OPureza:99.95%Forma y color:SolidPeso molecular:373.83CBFβ Inhibitor
CAS:<p>CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.</p>Fórmula:C12H14N2OSPureza:96.50%Forma y color:SolidPeso molecular:234.32NITD-2
CAS:<p>NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.</p>Fórmula:C23H19N3O4SPureza:98.03% - 99.46%Forma y color:SolidPeso molecular:433.48
![5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT8912.webp&w=3840&q=75)
