Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(115 productos)
- CDK(547 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(46 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(269 productos)
- Kinesina(87 productos)
- LIM quinasa(21 productos)
- Asociado a microtúbulos(273 productos)
- PKC(127 productos)
- PLK(25 productos)
- ROCK(61 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3912 productos de "Ciclo celular / Checkpoint"
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6-Mercaptopurine hydrate
CAS:6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.Fórmula:C5H6N4OSPureza:97.54% - 99.14%Forma y color:Light Yellow Crystalline PowderPeso molecular:170.19Ara-G
CAS:Ara-G, a deoxyguanosine analog, inhibits DNA synthesis, targeting T cell leukemia by converting to araGTP.Fórmula:C10H13N5O5Pureza:98.74%Forma y color:Slightly Off White To White PowderPeso molecular:283.24MLN8054 sodium
CAS:MLN8054 sodium is an Aurora A inhibitor.Fórmula:C25H14ClF2N4NaO2Forma y color:SolidPeso molecular:498.84Mogroside I E1
CAS:Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.Fórmula:C36H62O9Pureza:98.62% - 99.71%Forma y color:SolidPeso molecular:638.87Didox
CAS:Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.Fórmula:C7H7NO4Pureza:99.83%Forma y color:SolidPeso molecular:169.13Orbofiban
CAS:Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.Fórmula:C17H23N5O4Forma y color:SolidPeso molecular:361.4T56-LIMKi
CAS:T56-LIMKi (T5601640) is a selective inhibitor of LIMK2.Fórmula:C19H14F3N3O3Pureza:98.39% - 99.57%Forma y color:SolidPeso molecular:389.33IMP-1088
CAS:IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.Fórmula:C25H29F2N5OPureza:98.48% - 99.52%Forma y color:SolidPeso molecular:453.53Ref: TM-T9350
1mg137,00€2mg178,00€5mg268,00€1mL*10mM (DMSO)294,00€10mg444,00€25mg790,00€50mg1.063,00€Protein kinase inhibitor 6
CAS:Protein kinase inhibitor 6 is a protein kinase inhibitor.Fórmula:C13H9FN2SPureza:98.01%Forma y color:SolidPeso molecular:244.29Ref: TM-T9779
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg86,00€25mg163,00€50mg222,00€100mg324,00€200mg440,00€BTYNB
CAS:BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.Fórmula:C12H9BrN2OSPureza:≥95%Forma y color:SolidPeso molecular:309.18IXA4
CAS:IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1.Fórmula:C24H28N4O4Pureza:99.8% - 99.85%Forma y color:SolidPeso molecular:436.5RK33
CAS:"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."Fórmula:C23H20N6O3Pureza:99.04% - 99.72%Forma y color:SolidPeso molecular:428.44STF-083010
CAS:STF-083010 is a selective inhibitor of the IRE1α endonuclease.Fórmula:C15H11NO3S2Pureza:98.09% - 99.45%Forma y color:SolidPeso molecular:317.38Ref: TM-T6681
5mg49,00€1mL*10mM (DMSO)55,00€10mg75,00€25mg114,00€50mg193,00€100mg349,00€200mg527,00€500mg767,00€Datelliptium chloride hydrochloride
CAS:Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.
Fórmula:C23H29Cl2N3OPureza:99.46%Forma y color:SolidPeso molecular:434.4Cyclo(RADfK)
CAS:Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.Fórmula:C28H43N9O7Pureza:>99.99%Forma y color:SolidPeso molecular:617.76-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Fórmula:C10H13N5O3SPureza:97.52%Forma y color:SolidPeso molecular:283.31GNF4877
CAS:GNF4877 inhibits DYRK1A/GSK3β (IC50: 6/16 nM), blocks NFATc export, and boosts β-cell growth.Fórmula:C25H27FN6O4Pureza:98.68% - 99.40%Forma y color:SolidPeso molecular:494.52Cilengitide
CAS:Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Fórmula:C27H40N8O7Pureza:98% - 99.8%Forma y color:SolidPeso molecular:588.66Aplidine
CAS:Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM).Fórmula:C57H87N7O15Pureza:99.86%Forma y color:SolidPeso molecular:1110.34Ref: TM-T9715
1mg235,00€5mg588,00€10mg787,00€1mL*10mM (DMSO)938,00€25mg1.216,00€50mg1.568,00€100mg2.527,00€PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:CRT0066101 dihydrochloride is an inhibitor of PKD.Fórmula:C18H21Cl3N4OPureza:99.5%Forma y color:SolidPeso molecular:415.75Clevudine
CAS:Clevudine (Levovir) fights HBV, blocks viral DNA synthesis, and has a long half-life reducing relapse risk after treatment.Fórmula:C10H13FN2O5Pureza:99.88% - 99.97%Forma y color:SolidPeso molecular:260.22Hydroxyfasudil Hydrochloride
CAS:Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).Fórmula:C14H18ClN3O3SPureza:98.05%Forma y color:SolidPeso molecular:343.83Carotegrast methyl HCl
CAS:Carotegrast methyl (AJM300/PTC-100) is an oral α4 integrin blocker reducing inflammation and experimental colitis.Fórmula:C25H20Cl3N3O5Forma y color:SolidPeso molecular:548.801Atuveciclib
CAS:Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.Fórmula:C18H18FN5O2SPureza:98.8%Forma y color:SolidPeso molecular:387.43Ref: TM-T10464L
1mg84,00€2mg114,00€5mg192,00€1mL*10mM (DMSO)212,00€10mg313,00€25mg580,00€50mg773,00€100mg1.063,00€E7820
CAS:E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Forma y color:SolidPeso molecular:336.37Ref: TM-T4435
1mg34,00€2mg49,00€5mg65,00€1mL*10mM (DMSO)80,00€10mg84,00€25mg137,00€50mg200,00€100mg321,00€200mg477,00€LP-935509
CAS:LP-935509 is a selective, brain-permeable, small molecule competitive inhibitor of articulin-2-associated kinase 1 (AAK1).Cost-effective and quality-assured.Fórmula:C20H24N6O3Pureza:98.34% - 99.64%Forma y color:SolidPeso molecular:396.44Ref: TM-T15781
1mg37,00€2mg49,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg124,00€25mg239,00€50mg444,00€100mg647,00€AZD-5438
CAS:AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).Fórmula:C18H21N5O2SPureza:99.73% - 99.87%Forma y color:SolidPeso molecular:371.46EN4
CAS:EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.Fórmula:C25H24N2O4Pureza:98.51%Forma y color:SolidPeso molecular:416.47CID755673
CAS:CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.Fórmula:C12H11NO3Pureza:97.68% - 99.84%Forma y color:SolidPeso molecular:217.22SNS-314
CAS:SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.Fórmula:C18H15ClN6OS2Pureza:98%Forma y color:SolidPeso molecular:430.93Favipiravir
CAS:Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.Fórmula:C5H4FN3O2Pureza:97.32% - 99.90%Forma y color:SolidPeso molecular:157.1Arg-Gly-Asp TFA (99896-85-2(free base))
Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.Fórmula:C14H23F3N6O8Pureza:99.2% - ≥98%Forma y color:SolidPeso molecular:460.36SNS-314 Mesylate
CAS:SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.Fórmula:C18H15ClN6OS2·CH4O3SPureza:99.44% - 99.92%Forma y color:SolidPeso molecular:527.04Temozolomide Acid
CAS:TMZA, a TMZ metabolite, shows in vitro anticancer effects. TMZ, an oral alkylator, treats GBM and astrocytomas.Fórmula:C6H5N5O3Pureza:99.28%Forma y color:SolidPeso molecular:195.14SL327
CAS:SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.Fórmula:C16H12F3N3SPureza:97.98% - >99.99%Forma y color:SolidPeso molecular:335.35CDK9-IN-30
CAS:CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.Fórmula:C16H20FNO3Pureza:99.75%Forma y color:SolidPeso molecular:293.33Brequinar
CAS:Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.Fórmula:C23H15F2NO2Pureza:99.1% - 99.57%Forma y color:SolidPeso molecular:375.37NG 52
CAS:NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.Fórmula:C16H19ClN6OPureza:98% - 99.34%Forma y color:SolidPeso molecular:346.81LDC4297 hydrochloride
CAS:LDC4297 hydrochloride is a selective and potent CDK7 inhibitor with broad-spectrum antiviral activity, useful for research on viral infections.Fórmula:C23H29ClN8OForma y color:SolidPeso molecular:468.98PF-06873600
CAS:PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.Fórmula:C20H27F2N5O4SPureza:98.77% - 99.55%Forma y color:SolidPeso molecular:471.52Ref: TM-T8463
1mg54,00€5mg114,00€1mL*10mM (DMSO)118,00€10mg178,00€25mg334,00€50mg557,00€100mg888,00€200mg1.198,00€T-5224
CAS:T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcriptionFórmula:C29H27NO8Pureza:97.88% - 99.29%Forma y color:SolidPeso molecular:517.53Ref: TM-T5416
1mg48,00€5mg96,00€1mL*10mM (DMSO)107,00€10mg144,00€25mg254,00€50mg424,00€100mg627,00€200mg998,00€2'-Deoxy-2'-fluorocytidine
CAS:2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.Fórmula:C9H12FN3O4Pureza:99.90%Forma y color:White Or Almost White Crystalline PowderPeso molecular:245.21EG1
CAS:EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.Fórmula:C22H18N2O5Pureza:97.48%Forma y color:SolidPeso molecular:390.39Ref: TM-T27246
1mL*10mM (DMSO)33,00€2mg34,00€5mg54,00€10mg86,00€25mg130,00€50mg187,00€100mg260,00€200mg370,00€Hexapeptide-10 Acetate
Hexapeptide-10 Acetate (Hexapeptide-10 Acetate) is a synthetic peptide.Fórmula:C30H57N7O10Pureza:98.84%Forma y color:SolidPeso molecular:675.81WNK-IN-11
CAS:WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)Fórmula:C21H21Cl2N5OSPureza:98.32%Forma y color:SolidPeso molecular:462.4Ref: TM-T5456
1mg87,00€5mg172,00€1mL*10mM (DMSO)188,00€10mg280,00€25mg474,00€50mg683,00€100mg964,00€500mg1.918,00€Trifluridine/tipiracil hydrochloride mixture
CAS:Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in aFórmula:C29H34Cl2F6N8O12Pureza:98% - 99.79%Forma y color:SolidPeso molecular:871.53Ref: TM-T3658
2mg37,00€5mg54,00€1mL*10mM (DMSO)73,00€10mg93,00€25mg148,00€50mg236,00€100mg358,00€200mg538,00€500mg842,00€NU2058
CAS:NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.Fórmula:C12H17N5OPureza:99.34% - 99.92%Forma y color:SolidPeso molecular:247.3Ref: TM-T3186
10mg42,00€1mL*10mM (DMSO)47,00€25mg78,00€50mg106,00€100mg160,00€200mg230,00€500mg378,00€WR99210 hydrochloride(47326-86-3 free base)
CAS:WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.Fórmula:C14H19Cl4N5O2Pureza:97.77% - 99.8%Forma y color:SolidPeso molecular:431.14Ref: TM-T17257L
1mg62,00€5mg132,00€1mL*10mM (DMSO)157,00€10mg200,00€25mg338,00€50mg497,00€100mg708,00€200mg954,00€NSC632839
CAS:NSC-632839 (Ubiquitin Isopeptidase Inhibitor II) is a nonselective isopeptidase inhibitor, which inhibits USP2 (EC50: 45±4 μM), USP7 (EC50: 37±1 μM), and SENP2Fórmula:C21H22ClNOPureza:99.74% - 99.88%Forma y color:SolidPeso molecular:339.86AZ191
CAS:AZ191（IC50 of 17 nM） is an effective and specific DYRK1B inhibitor.Fórmula:C24H27N7OPureza:98.04% - 99.65%Forma y color:SolidPeso molecular:429.52TP-353
CAS:TP-353 (EOS-61973) is a CDK7 inhibitor.Fórmula:C35H30FNO3Pureza:99.12%Forma y color:SolidPeso molecular:531.62Ref: TM-T22440
1mg43,00€5mg80,00€1mL*10mM (DMSO)105,00€10mg129,00€25mg225,00€50mg314,00€100mg432,00€200mg597,00€ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Fórmula:C21H25N7Pureza:97.63% - ≥95%Forma y color:SolidPeso molecular:375.47Fosifloxuridine nafalbenamide
CAS:Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.
Fórmula:C29H29FN3O9PPureza:95.87%Forma y color:SolidPeso molecular:613.531,4-Anthraquinone
CAS:1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.Fórmula:C14H8O2Pureza:95.96% - 97.01%Forma y color:Orange Brown SolidPeso molecular:208.21GLPG0187
CAS:GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).Fórmula:C29H37N7O5SPureza:99.4% - 99.70%Forma y color:SolidPeso molecular:595.71Ref: TM-T4259
1mg44,00€5mg98,00€1mL*10mM (DMSO)129,00€10mg144,00€25mg236,00€50mg350,00€100mg522,00€500mg1.134,00€APTO-253 HCl
CAS:APTO-253 (LOR-253/LT-253) is a small-molecule MTF-1 inhibitor with antitumor properties, reducing cyclin D1, hypoxia, and angiogenesis gene expression.Fórmula:C22H15ClFN5Forma y color:SolidPeso molecular:403.84Roniciclib
CAS:Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.Fórmula:C18H21F3N4O3SPureza:98% - 98.63%Forma y color:SolidPeso molecular:430.44BI-1347
CAS:BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.Fórmula:C22H20N4OPureza:96.7% - 99.63%Forma y color:SolidPeso molecular:356.42Ref: TM-T5405
1mg40,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg126,00€25mg240,00€50mg439,00€100mg647,00€500mg1.359,00€HA-100 hydrochloride
CAS:HA-100 hydrochloride inhibits protein kinases PKG, PKA, PKC, MLC-kinase (IC50: 4-240 μM) and ROCK.Fórmula:C13H16ClN3O2SForma y color:SolidPeso molecular:313.8THZ1
CAS:THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.Fórmula:C31H28ClN7O2Pureza:97.42% - 99.27%Forma y color:SolidPeso molecular:566.05EOAI3402143
CAS:EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis.Fórmula:C25H28Cl2N4O3Pureza:99.6%Forma y color:SolidPeso molecular:503.42Ref: TM-T11209
1mg63,00€5mg137,00€1mL*10mM (DMSO)152,00€10mg215,00€25mg423,00€50mg680,00€100mg1.009,00€TH588
CAS:TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.Fórmula:C13H12Cl2N4Pureza:96.05% - 99.82%Forma y color:SolidPeso molecular:295.17MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Fórmula:C25H15ClF2N4O2Pureza:98.07% - 98.26%Forma y color:SolidPeso molecular:476.86Ref: TM-T6315
1mg50,00€2mg67,00€5mg84,00€1mL*10mM (DMSO)88,00€10mg120,00€25mg220,00€50mg356,00€100mg537,00€CCT245737
CAS:CCT245737 is an orally active, selective Chk1 inhibitor, and is >1,000-fold selective over CHK2 and CDK1.Cost-effective and quality-assured.Fórmula:C16H16F3N7OPureza:98.28% - 99.93%Forma y color:SolidPeso molecular:379.34Ref: TM-T7080
1mg37,00€2mg49,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg113,00€25mg213,00€50mg350,00€100mg523,00€DHFR-IN-3
CAS:DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.Fórmula:C8H7BrN4Pureza:99.521% - 99.65%Forma y color:SolidPeso molecular:239.07Brr2-IN-3
CAS:Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.Fórmula:C24H20N4O3SPureza:99.26%Forma y color:SolidPeso molecular:444.51Ref: TM-T22282
1mg52,00€2mg65,00€5mg92,00€1mL*10mM (DMSO)110,00€10mg161,00€25mg290,00€50mg420,00€100mg587,00€200mg792,00€Simeprevir
CAS:Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.Fórmula:C38H47N5O7S2Pureza:99.45% - 99.92%Forma y color:SolidPeso molecular:749.94CW-069
CAS:CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.Fórmula:C23H21IN2O3Pureza:97.52% - 99.52%Forma y color:SolidPeso molecular:500.33Ref: TM-T6209
1mg40,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg118,00€25mg205,00€50mg290,00€100mg409,00€500mg888,00€Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Fórmula:C32H46O8Pureza:97.1% - 99.93%Forma y color:SolidPeso molecular:558.70Pritelivir
CAS:Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).Fórmula:C18H18N4O3S2Pureza:97.96% - 99.42%Forma y color:SolidPeso molecular:402.49ROCK-IN-2
CAS:ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.Fórmula:C18H13ClF2N6OPureza:97.29%Forma y color:SolidPeso molecular:402.79Ref: TM-TQ0110
1mg108,00€5mg260,00€1mL*10mM (DMSO)353,00€10mg416,00€25mg690,00€50mg964,00€100mg1.305,00€BSJ-03-123
CAS:BSJ-03-123 is a potent, CDK6-selective small-molecule degrader.Fórmula:C47H56N10O11Pureza:97.78% - 99.38%Forma y color:SolidPeso molecular:937.01Ref: TM-T5395
1mg87,00€2mg113,00€5mg177,00€10mg259,00€25mg409,00€50mg560,00€100mg800,00€500mg1.611,00€Y16
CAS:Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Fórmula:C24H20N2O3Pureza:98.26% - 99.85%Forma y color:SolidPeso molecular:384.43Ref: TM-T3553
1mg34,00€2mg48,00€5mg70,00€1mL*10mM (DMSO)77,00€10mg109,00€25mg177,00€50mg263,00€100mg389,00€CKI-7 free base
CAS:CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Fórmula:C11H12ClN3O2SForma y color:SolidPeso molecular:285.75MC180295
CAS:MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.Fórmula:C17H18N4O3SPureza:99.84%Forma y color:SolidPeso molecular:358.41Ref: TM-T5533
1mg52,00€5mg124,00€1mL*10mM (DMSO)136,00€10mg177,00€25mg301,00€50mg424,00€100mg605,00€200mg797,00€SBC-115337
CAS:SBC-115337 is a PCSK9 inhibitor.Fórmula:C29H19N3O4Pureza:99.41%Forma y color:SolidPeso molecular:473.48NSAH
CAS:NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-Fórmula:C18H14N2O3Pureza:99.27%Forma y color:SolidPeso molecular:306.32GDC-0575
CAS:GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).Fórmula:C16H20BrN5OPureza:≥95%Forma y color:SolidPeso molecular:378.27AT9283
CAS:AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).
Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Forma y color:SolidPeso molecular:381.43BS-181 hydrochloride
CAS:BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Fórmula:C22H32N6·HClPureza:99.21%Forma y color:SolidPeso molecular:416.99Ref: TM-T6162
200mgA consultar1mg37,00€2mg52,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg116,00€25mg250,00€50mg416,00€100mg645,00€COH29
CAS:COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.Fórmula:C22H16N2O5SPureza:97.04% - 98.92%Forma y color:SolidPeso molecular:420.44Ref: TM-T3157
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg178,00€50mg334,00€100mg557,00€200mg790,00€NVP-LCQ195
CAS:NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).Fórmula:C17H19Cl2N5O4SPureza:99.56% - 99.85%Forma y color:SolidPeso molecular:460.33Ref: TM-TQ0068
1mg46,00€5mg92,00€1mL*10mM (DMSO)94,00€10mg138,00€25mg255,00€50mg374,00€100mg533,00€200mg705,00€CHR-6494
CAS:CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).Fórmula:C16H16N6Pureza:98.78%Forma y color:SolidPeso molecular:292.34Ref: TM-T14959
5mg54,00€1mL*10mM (DMSO)60,00€10mg82,00€25mg145,00€50mg259,00€100mg442,00€200mg643,00€Senexin A
CAS:Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.Fórmula:C17H14N4Pureza:99.74%Forma y color:SolidPeso molecular:274.32Ref: TM-T5673
1mg34,00€1mL*10mM (DMSO)71,00€5mg73,00€10mg94,00€25mg177,00€50mg323,00€100mg460,00€200mg622,00€N1-Methylpseudouridine
CAS:N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms byFórmula:C10H14N2O6Pureza:98.95% - 99.88%Forma y color:SolidPeso molecular:258.23APY29
CAS:APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.Fórmula:C17H16N8Pureza:96.51% - 98.46%Forma y color:SolidPeso molecular:332.36Ref: TM-T3654
2mg40,00€5mg62,00€1mL*10mM (DMSO)67,00€10mg90,00€25mg167,00€50mg285,00€100mg515,00€500mg1.071,00€URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Fórmula:C27H27N5Pureza:99.32% - 99.98%Forma y color:SolidPeso molecular:421.54Talotrexin
CAS:Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.Fórmula:C27H27N9O6Forma y color:SolidPeso molecular:573.56Fialuridine
CAS:Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.Fórmula:C9H10FIN2O5Pureza:99.71% - 99.88%Forma y color:Less Crystals Colourless CrystalsPeso molecular:372.09WNK463
CAS:WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).Fórmula:C21H24F3N7O2Pureza:>99.99% - ≥95%Forma y color:SolidPeso molecular:463.46NSC23005 Sodium
CAS:NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.Fórmula:C13H16NNaO4SPureza:99.64%Forma y color:SolidPeso molecular:305.32Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Fórmula:C5H7N6NaO5SPureza:99.55%Forma y color:SolidPeso molecular:286.2LJI308
CAS:LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.Fórmula:C21H18F2N2O2Pureza:99.73% - 99.87%Forma y color:SolidPeso molecular:368.38MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Fórmula:C9H7NO4Pureza:98.53%Forma y color:Yellow PowderPeso molecular:193.166-AZATHYMINE
CAS:6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.Fórmula:C4H5N3O2Pureza:99.47%Forma y color:SolidPeso molecular:127.1SCH900776
CAS:SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.Fórmula:C15H18BrN7Pureza:96.69% - 99.6%Forma y color:SolidPeso molecular:376.25Eprociclovir potassium
CAS:Eprociclovir potassium, 15x stronger than acyclovir, inhibits EHV1 and human herpesviruses, also treats herpetic keratitis effectively with eyedrops.Fórmula:C11H15KN5O3Forma y color:SolidPeso molecular:304.37NY2267
CAS:NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethylFórmula:C38H43N3O6Pureza:99.16% - 99.27%Forma y color:SolidPeso molecular:637.76α2β1 Integrin Ligand Peptide acetate
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.Fórmula:C16H26N4O11Pureza:98.46%Forma y color:SolidPeso molecular:450.4LY2334737
CAS:LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.Fórmula:C17H25F2N3O5Pureza:98.82%Forma y color:SolidPeso molecular:389.39Ref: TM-T4061
1mg35,00€5mg79,00€1mL*10mM (DMSO)94,00€10mg111,00€25mg215,00€50mg319,00€100mg442,00€200mg583,00€
