Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
Mostrar 10 subcategorías más
Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
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Teplizumab
CAS:<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Pureza:SDS-PAGE:95.8%;SEC-HPLC:99.7%Forma y color:LiquidPeso molecular:145.79 kDaOrbofiban TFA
CAS:<p>Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary</p>Fórmula:C19H24F3N5O6Pureza:97.21% - 98.72%Forma y color:SolidPeso molecular:475.426-Mercaptopurine
CAS:<p>6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.</p>Fórmula:C5H4N4SPureza:99.53% - 99.63%Forma y color:Yellow Crystalline Powder SolidPeso molecular:152.18Levofloxacin hydrate
CAS:<p>Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Fórmula:C18H20FN3O4H2OPureza:98.26%Forma y color:Pale Yellow SolidPeso molecular:370.38ATN-161 trifluoroacetate salt
CAS:<p>ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.</p>Fórmula:C25H36F3N9O10SPureza:98% - 99.98%Forma y color:SolidPeso molecular:711.67BMS-1001 hydrochloride
CAS:<p>BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect</p>Fórmula:C35H35ClN2O7Pureza:97.36%Forma y color:SolidPeso molecular:631.11TAK-901
CAS:<p>TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others</p>Fórmula:C28H32N4O3SPureza:99.02% - 99.59%Forma y color:SolidPeso molecular:504.64Abciximab
CAS:<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Pureza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Forma y color:LiquidPeso molecular:95.18 kDaRifaximin
CAS:<p>Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.</p>Fórmula:C43H51N3O11Pureza:99.18% - 99.40%Forma y color:Red-Orange Crystalline PowderPeso molecular:785.88HLM006474
CAS:<p>HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 μM in A375 cells).</p>Fórmula:C25H25N3O2Pureza:98.45% - 99.04%Forma y color:SolidPeso molecular:399.48Avotaciclib
CAS:<p>Avotaciclib (BEY1107) is a potent and orally active cyclin dependent kinase 1 (CDK1) inhibitor.Avotaciclib can be used to study locally advanced or metastatic</p>Fórmula:C13H11N7OPureza:98.02%Forma y color:SolidPeso molecular:281.27Lerociclib dihydrochloride
CAS:<p>Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/</p>Fórmula:C26H36Cl2N8OPureza:97.4%Forma y color:SolidPeso molecular:547.52Foralumab
CAS:<p>Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.</p>Pureza:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Forma y color:LiquidBMVC-8C3O
CAS:<p>BMVC-8C3O is a DNA G-quadruplex (G4) ligand.Cost-effective and quality-assured.</p>Fórmula:C42H53I3N4O3Pureza:99.72%Forma y color:SolidPeso molecular:1042.61Trilaciclib hydrochloride
CAS:<p>Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).</p>Fórmula:C24H32Cl2N8OPureza:99.69% - 99.89%Forma y color:SolidPeso molecular:519.47NU6140
CAS:<p>NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).</p>Fórmula:C23H30N6O2Pureza:98.33%Forma y color:SolidPeso molecular:422.52MYCi975
CAS:<p>MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.</p>Fórmula:C25H16Cl2F6N2O2Pureza:99.3% - 99.82%Forma y color:SolidPeso molecular:561.3Cirtuvivint
CAS:<p>Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.</p>Fórmula:C24H25N7OPureza:99.46% - >99.99%Forma y color:SolidPeso molecular:427.5Cinoxacin
CAS:<p>Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.</p>Fórmula:C12H10N2O5Pureza:99.62% - 99.98%Forma y color:SolidPeso molecular:262.22Cibisatamab
CAS:<p>Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.</p>Pureza:SDS-PAGE:99.1%;SEC-HPLC:96.5%Forma y color:LiquidPeso molecular:191.1 kDaButylparaben
CAS:<p>Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity.</p>Fórmula:C11H14O3Pureza:98.15%Forma y color:Small Colorless Crystals Or Powder Tongue Aqueous Solutions Slightly Acidic To Litmus (Ntp 1992)Peso molecular:194.23LY 345899
CAS:<p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>Fórmula:C20H21N7O7Pureza:99.7%Forma y color:SolidPeso molecular:471.42BT173
CAS:<p>BT173 is a novel inhibitor of homeodomain interacting protein kinase 2 (HIPK2 ), attenuating renal fibrosis through suppression of the TGF-ß1/Smad3 pathway.</p>Fórmula:C18H12BrN3O2Pureza:98.247%Forma y color:SolidPeso molecular:382.21Procaine
CAS:<p>Procaine (Vitamin H3) is a slow-acting ester local anesthetic with a short effect, used for infiltration, nerve, and spinal blocks.</p>Fórmula:C13H20N2O2Pureza:99.57% - 99.73%Forma y color:Anhydrous Plates Tables From Ligroin Or Ether SolidPeso molecular:236.31Tidutamab
CAS:<p>Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).</p>Pureza:97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Forma y color:LiquidOtelixizumab
CAS:<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Pureza:>95%Forma y color:LiquidJH-RE-06
CAS:<p>JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.</p>Fórmula:C20H16Cl3N3O4Pureza:99.29%Forma y color:SolidPeso molecular:468.72Carmofur
CAS:<p>Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.</p>Fórmula:C11H16FN3O3Pureza:98.53% - 99.98%Forma y color:SolidPeso molecular:257.26Mps1-IN-3
CAS:<p>Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).</p>Fórmula:C26H31N7O4SPureza:99.25%Forma y color:SolidPeso molecular:537.63Hu7691 free base
CAS:<p>Hu7691 free base is an Akt inhibitor that inhibits Akt1, Akt2 and Akt3 and induces differentiation of neuroblastoma cells.</p>Fórmula:C22H21F3N4OPureza:98.89%Forma y color:SolidPeso molecular:414.423GSK-1520489A
CAS:<p>GSK-1520489A is an active PKMYT1 inhibitor.</p>Fórmula:C21H23N5O3SPureza:99.85%Forma y color:SolidPeso molecular:425.5Enrofloxacin
CAS:<p>Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.</p>Fórmula:C19H22FN3O3Pureza:99.43% - >99.99%Forma y color:Pale Yellow CrystalsPeso molecular:359.39SU056
CAS:<p>SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.</p>Fórmula:C20H16FNO5Pureza:99.89%Forma y color:SoildPeso molecular:369.34R-10015
CAS:<p>R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.</p>Fórmula:C20H19ClN6O2Pureza:98.68%Forma y color:SolidPeso molecular:410.86XPW1
CAS:<p>XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.</p>Fórmula:C36H39ClFN7O2Pureza:98.08%Forma y color:SoildPeso molecular:656.19Vitamin D2
CAS:<p>Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.</p>Fórmula:C28H44OPureza:98.73% - 99.89%Forma y color:Prisms From Acetone 1998)Peso molecular:396.65Efalizumab
CAS:<p>Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.</p>Pureza:SDS-PAGE:95% SEC-HPLC:98.77%Forma y color:LiquidPeso molecular:146.14 kDaHycanthone
CAS:<p>Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.</p>Fórmula:C20H24N2O2SPureza:98.78%Forma y color:Yellow-Orange Powder (Ntp 1992)Peso molecular:356.48DI-87
CAS:<p>DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.</p>Fórmula:C23H30N6O3S2Pureza:99.76%Forma y color:SolidPeso molecular:502.65Ceftriaxone sodium hydrate
CAS:<p>Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.</p>Fórmula:C18H16N8Na2O7S3·5H2OPureza:99.77% - 99.78%Forma y color:White Or Almost White Crystalline Powder OdorlessPeso molecular:661.6Abrilumab
CAS:<p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>Pureza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Forma y color:LiquidCyclin K degrader 1
<p>Cyclin K degrader 1 is a Cyclin K degrader.Cyclin K degrader 1 is a degrader converted from AT-7519.Cyclin K degrader 1 has weak degrading activity against Cyclin K but does not result in a sustained decrease in degradation affinity.Cyclin K degrader 1 is a degrader converted from AT-7519.</p>Fórmula:C23H17Cl2N5O2Pureza:99.76%Forma y color:SolidPeso molecular:466.32Metarrestin
CAS:<p>Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.</p>Fórmula:C31H30N4OPureza:99.45%Forma y color:SolidPeso molecular:474.6Gemifloxacin mesylate
CAS:<p>Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually</p>Fórmula:C19H24FN5O7SPureza:97.24% - ≥95%Forma y color:Beige SolidPeso molecular:485.49hSMG-1 inhibitor 11j
CAS:<p>hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, >455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.</p>Fórmula:C27H28ClN7O3SPureza:99.22% - 99.65%Forma y color:SolidPeso molecular:566.07Ribociclib succinate
CAS:<p>Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).</p>Fórmula:C27H36N8O5Pureza:99.9%Forma y color:SolidPeso molecular:552.63CDK2-IN-4
CAS:<p>CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.</p>Fórmula:C23H18N6O2SPureza:97.24% - 99.10%Forma y color:SolidPeso molecular:442.49Tadocizumab
CAS:<p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>Pureza:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Forma y color:LiquidTAO Kinase inhibitor 2
CAS:<p>TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.</p>Fórmula:C25H24N2O3Pureza:98.58%Forma y color:SoildPeso molecular:400.47MKC8866
CAS:<p>MKC8866, a selective IRE1 RNase inhibitor with an IC50 of 0.29 μM, curbs breast and prostate cancer cell growth.</p>Fórmula:C18H19NO7Pureza:99.28% - 99.854%Forma y color:SolidPeso molecular:361.35
