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Ciclo celular / Checkpoint

Ciclo celular / Checkpoint

Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.

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Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"

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  • RWJ 50271

    CAS:
    <p>RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.</p>
    Fórmula:C18H17F3N4O2S
    Pureza:99.09%
    Forma y color:Solid
    Peso molecular:410.41
  • MKC9989

    CAS:
    <p>MKC9989 is an inhibitor of Hydroxy aryl aldehydes (HAA). MKC9989 also inhibits IRE1α with an IC50 of 0.23 to 44 μM.</p>
    Fórmula:C17H20O7
    Pureza:99.3%
    Forma y color:Solid
    Peso molecular:336.34
  • BMS-1001 hydrochloride

    CAS:
    <p>BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect</p>
    Fórmula:C35H35ClN2O7
    Pureza:97.36%
    Forma y color:Solid
    Peso molecular:631.11
  • Nedaplatin

    CAS:
    <p>Nedaplatin, a cisplatin derivative, induces tumor DNA damage (IC50: 94 μM) through platinum-DNA cross-links, causing apoptosis.</p>
    Fórmula:C2H8N2O3Pt
    Pureza:99.88% - >99.99%
    Forma y color:Straw Yellow Powder
    Peso molecular:303.17
  • Ganciclovir

    CAS:
    <p>Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus.</p>
    Fórmula:C9H13N5O4
    Pureza:99.55% - 99.58%
    Forma y color:White Powder
    Peso molecular:255.23
  • Procaine hydrochloride

    CAS:
    <p>Procaine HCl is a benzoic acid derivative used as a local anesthetic, blocking nerve impulses and sensation.</p>
    Fórmula:C13H20N2O2·HCl
    Pureza:99.1% - 99.22%
    Forma y color:White Crystalline Powder
    Peso molecular:272.77
  • Teplizumab

    CAS:
    <p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>
    Pureza:SDS-PAGE:95.8%;SEC-HPLC:99.7%
    Forma y color:Liquid
    Peso molecular:145.79 kDa
  • BMVC-8C3O

    CAS:
    <p>BMVC-8C3O is a DNA G-quadruplex (G4) ligand.Cost-effective and quality-assured.</p>
    Fórmula:C42H53I3N4O3
    Pureza:99.72%
    Forma y color:Solid
    Peso molecular:1042.61
  • Trimethoprim

    CAS:
    <p>Trimethoprim (NSC-106568) inhibits dihydrofolate reductase, CYP2C8, and OCT2 - an antibacterial agent.</p>
    Fórmula:C14H18N4O3
    Pureza:99.80% - 99.81%
    Forma y color:White To Yellowish Powder
    Peso molecular:290.32
  • Pefloxacin Mesylate Dihydrate

    CAS:
    <p>Pefloxacin Mesylate Dihydrate (1589 RB) , an antibacterial agent, restrains bacterial DNA replication by inhibiting DNA gyrase (topoisomerase).</p>
    Fórmula:C17H20FN3O3·CH4O3S·2H2O
    Pureza:99.79%
    Forma y color:Solid
    Peso molecular:465.49
  • MYCi361

    CAS:
    <p>MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).</p>
    Fórmula:C26H16ClF9N2O2
    Pureza:99.52%
    Forma y color:Solid
    Peso molecular:594.86
  • KJ Pyr 9

    CAS:
    <p>KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).</p>
    Fórmula:C22H15N3O4
    Pureza:99.56% - ≥98%
    Forma y color:Solid
    Peso molecular:385.37
  • Vedolizumab

    CAS:
    <p>Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.</p>
    Pureza:SDS-PAGE:98.4%;SEC-HPLC:99.1%
    Forma y color:Liquid
    Peso molecular:146.80 kDa
  • dAURK-4 hydrochloride


    <p>dAURK-4 hydrochloride, a derivative of Alisertib, functions as a potent and selective degrader of AURKA (Aurora A), exhibiting anticancer properties [1].</p>
    Fórmula:C52H53Cl2FN8O12
    Pureza:99.44%
    Forma y color:Solid
    Peso molecular:1071.93
  • Rifaximin

    CAS:
    <p>Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.</p>
    Fórmula:C43H51N3O11
    Pureza:99.18% - 99.40%
    Forma y color:Red-Orange Crystalline Powder
    Peso molecular:785.88
  • Levofloxacin hydrate

    CAS:
    <p>Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>
    Fórmula:C18H20FN3O4H2O
    Pureza:98.26%
    Forma y color:Pale Yellow Solid
    Peso molecular:370.38
  • Otelixizumab

    CAS:
    <p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>
    Pureza:>95%
    Forma y color:Liquid
  • Hu7691 free base

    CAS:
    <p>Hu7691 free base is an Akt inhibitor that inhibits Akt1, Akt2 and Akt3 and induces differentiation of neuroblastoma cells.</p>
    Fórmula:C22H21F3N4O
    Pureza:98.89%
    Forma y color:Solid
    Peso molecular:414.423
  • Tegafur

    CAS:
    <p>Tegafur (FT 207) is a congener of the antimetabolite fluorouracil with antineoplastic activity.</p>
    Fórmula:C8H9FN2O3
    Pureza:99.16% - 99.89%
    Forma y color:White Crystalline Powder
    Peso molecular:200.17
  • SIBA

    CAS:
    <p>SIBA, a synthetic SAH analog, inhibits SAM-dependent transmethylation and blocks HSV-1 replication.</p>
    Fórmula:C14H21N5O3S
    Pureza:99.48%
    Forma y color:Solid
    Peso molecular:339.41
  • BAY-524

    CAS:
    <p>BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP).</p>
    Fórmula:C24H24F2N6O3
    Pureza:98.68% - 99.57%
    Forma y color:Solid
    Peso molecular:482.48
  • Nadifloxacin

    CAS:
    <p>Nadifloxacin (OPC7251) has been used in trials studying the treatment of Acne Vulgaris.</p>
    Fórmula:C19H21FN2O4
    Pureza:99.03% - 99.7%
    Forma y color:Off-White Crystalline Solid
    Peso molecular:360.38
  • Doxifluridine

    CAS:
    <p>Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity.</p>
    Fórmula:C9H11FN2O5
    Pureza:99.47% - 99.86%
    Forma y color:White Solid
    Peso molecular:246.19
  • CDK4/6-IN-2

    CAS:
    <p>CDK4/6-IN-2 是一种CDK4和CDK6抑制剂,IC50分别为 2.7 和 16 nM。</p>
    Fórmula:C27H32F2N8
    Pureza:99.47%
    Forma y color:Solid
    Peso molecular:506.59
  • Folinic acid calcium

    CAS:
    <p>Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.</p>
    Fórmula:C20H21CaN7O7
    Pureza:98.72% - >99.99%
    Forma y color:Yellow Crystalline Powder
    Peso molecular:511.51
  • Kira8

    CAS:
    <p>Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity (IC50: 5.9 nM).</p>
    Fórmula:C31H29ClN6O3S
    Pureza:98.07%
    Forma y color:Solid
    Peso molecular:601.12
  • MBQ-167

    CAS:
    <p>MBQ-167 is a dual inhibitor of Rac/Cdc42 (IC50s: 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively).</p>
    Fórmula:C22H18N4
    Pureza:98.07% - 99.52%
    Forma y color:Solid
    Peso molecular:338.41
  • BOS-172722

    CAS:
    <p>BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).</p>
    Fórmula:C24H30N8O
    Pureza:99.37%
    Forma y color:Solid
    Peso molecular:446.55
  • Enoxacin

    CAS:
    <p>Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.</p>
    Fórmula:C15H17FN4O3
    Pureza:98.68% - 99.89%
    Forma y color:Off-White To Yellow Crystals
    Peso molecular:320.32
  • Folinic Acid Calcium Salt Pentahydrate

    CAS:
    <p>Folinic Acid Calcium Salt Pentahydrate (Leucovorin Calcium Pentahydrate), a reduced folic acid, is used in combination with other chemotherapeutics.</p>
    Fórmula:C20H21CaN7O7·5H2O
    Pureza:99.17% - >99.99%
    Forma y color:Yellowish-White To Yellow Powder
    Peso molecular:601.58
  • Tadocizumab

    CAS:
    <p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>
    Pureza:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)
    Forma y color:Liquid
  • Cibisatamab

    CAS:
    <p>Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.</p>
    Pureza:SDS-PAGE:99.1%;SEC-HPLC:96.5%
    Forma y color:Liquid
    Peso molecular:191.1 kDa
  • Butylparaben

    CAS:
    <p>Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity.</p>
    Fórmula:C11H14O3
    Pureza:98.15%
    Forma y color:Small Colorless Crystals Or Powder Tongue Aqueous Solutions Slightly Acidic To Litmus (Ntp 1992)
    Peso molecular:194.23
  • HLM006474

    CAS:
    <p>HLM006474 is a pan inhibitor of E2F. This inhibits E2F4 DNA-binding (IC50: 29.8 μM in A375 cells).</p>
    Fórmula:C25H25N3O2
    Pureza:98.45% - 99.04%
    Forma y color:Solid
    Peso molecular:399.48
  • Procaine

    CAS:
    <p>Procaine (Vitamin H3) is a slow-acting ester local anesthetic with a short effect, used for infiltration, nerve, and spinal blocks.</p>
    Fórmula:C13H20N2O2
    Pureza:99.57% - 99.73%
    Forma y color:Anhydrous Plates Tables From Ligroin Or Ether Solid
    Peso molecular:236.31
  • Tidutamab

    CAS:
    <p>Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).</p>
    Pureza:97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)
    Forma y color:Liquid
  • ATN-161 trifluoroacetate salt

    CAS:
    <p>ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.</p>
    Fórmula:C25H36F3N9O10S
    Pureza:98% - 99.98%
    Forma y color:Solid
    Peso molecular:711.67
  • Foralumab

    CAS:
    <p>Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.</p>
    Pureza:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)
    Forma y color:Liquid
  • Orbofiban TFA

    CAS:
    <p>Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary</p>
    Fórmula:C19H24F3N5O6
    Pureza:97.21% - 98.72%
    Forma y color:Solid
    Peso molecular:475.42
  • MKC8866

    CAS:
    <p>MKC8866, a selective IRE1 RNase inhibitor with an IC50 of 0.29 μM, curbs breast and prostate cancer cell growth.</p>
    Fórmula:C18H19NO7
    Pureza:99.28% - 99.854%
    Forma y color:Solid
    Peso molecular:361.35
  • Rifapentine

    CAS:
    <p>Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.</p>
    Fórmula:C47H64N4O12
    Pureza:95.74% - ≥98%
    Forma y color:Solid
    Peso molecular:877.03
  • TK216

    CAS:
    <p>TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.</p>
    Fórmula:C19H15Cl2NO3
    Pureza:97.22%
    Forma y color:Solid
    Peso molecular:376.23
  • Monalizumab

    CAS:
    <p>Monalizumab, a humanized antibody, enhances NK cell function by inhibiting NKG2A; used in HNSCC studies.</p>
    Pureza:95% - > 95%
    Forma y color:Liquid
    Peso molecular:147 kDa (average)
  • NMDI14

    CAS:
    <p>NMDI14 is an inhibitor of nonsense mediated RNA decay (NMD).</p>
    Fórmula:C21H25N3O4S
    Pureza:97.79% - 99.37%
    Forma y color:Solid
    Peso molecular:415.51
  • DNA2 inhibitor C5

    CAS:
    <p>DNA2 inhibitor C5 is a specific cancer sensitizer with an IC50 of 20 μM, targeting multiple DNA2 activities.</p>
    Fórmula:C10H6N2O5
    Pureza:99.05%
    Forma y color:Solid
    Peso molecular:234.16
  • Pazufloxacin Mesylate

    CAS:
    <p>Pazufloxacin Mesylate (T-3762) is a fluoroquinolone antibiotic.</p>
    Fórmula:C16H15FN2O4·CH4O3S
    Pureza:99.88% - 99.93%
    Forma y color:Crystalline Solid
    Peso molecular:414.4
  • RG7800

    CAS:
    <p>RG7800 (RO6885247) has the potential for spinal muscular atrophy treatment. RG7800 is an SMN2 splicing modifier.</p>
    Fórmula:C24H28N6O
    Pureza:99.44%
    Forma y color:Solid
    Peso molecular:416.52
  • PZL-A

    CAS:
    <p>PZL-A, PZL-A, an activator of mtDNA synthesis, restored the activity of POLγ mutant variant.</p>
    Fórmula:C19H17ClN4O2
    Pureza:99.88%
    Forma y color:Soild
    Peso molecular:368.82
  • CMPD101

    CAS:
    <p>CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).</p>
    Fórmula:C24H21F3N6O
    Pureza:99.01% - 99.04%
    Forma y color:Solid
    Peso molecular:466.46
  • Oxolinic acid

    CAS:
    <p>Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.</p>
    Fórmula:C13H11NO5
    Pureza:98.39% - 99.72%
    Forma y color:Crystals From Dimethylformamide White Crystalline Powder
    Peso molecular:261.23
  • Abituzumab

    CAS:
    <p>Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.</p>
    Pureza:>95%
    Forma y color:Liquid
  • Bersanlimab

    CAS:
    <p>Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.</p>
    Pureza:> 95% - > 95%
    Forma y color:Liquid
    Peso molecular:144.22 kDa
  • CHK1-IN-4 hydrochloride


    <p>CHK1-IN-4 hydrochloride is a potent inhibitor of checkpoint kinase 1 (chk1).</p>
    Fórmula:C18H19BrClN7O2
    Pureza:99.29%
    Forma y color:Soild
    Peso molecular:480.75
  • Ribociclib succinate

    CAS:
    <p>Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).</p>
    Fórmula:C27H36N8O5
    Pureza:99.9%
    Forma y color:Solid
    Peso molecular:552.63
  • JH-RE-06

    CAS:
    <p>JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.</p>
    Fórmula:C20H16Cl3N3O4
    Pureza:99.29%
    Forma y color:Solid
    Peso molecular:468.72
  • Cinoxacin

    CAS:
    <p>Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.</p>
    Fórmula:C12H10N2O5
    Pureza:99.62% - 99.98%
    Forma y color:Solid
    Peso molecular:262.22
  • Danofloxacin mesylate

    CAS:
    <p>Danofloxacin mesylate (CP 76136-27) is a synthetic antibacterial agent of the fluoroquinolone class, acts principally by the inhibition of bacterial DNA-gyrase.</p>
    Fórmula:C19H20FN3O3·CH4O3S
    Pureza:99.73%
    Forma y color:Crystalline Solid
    Peso molecular:453.48
  • Valacyclovir hydrochloride

    CAS:
    <p>Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an acyclovir prodrug that inhibits viral DNA replication after metabolization.</p>
    Fórmula:C13H20N6O4·HCl
    Pureza:98.65% - ≥95%
    Forma y color:White To Off-White Crystalline Power
    Peso molecular:360.80
  • Mps1-IN-3

    CAS:
    <p>Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).</p>
    Fórmula:C26H31N7O4S
    Pureza:99.25%
    Forma y color:Solid
    Peso molecular:537.63
  • ART558

    CAS:
    <p>ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM).</p>
    Fórmula:C21H21F3N4O2
    Pureza:99.18% - 99.67%
    Forma y color:Solid
    Peso molecular:418.41
  • Simurosertib

    CAS:
    <p>Simurosertib (TAK-931) is a selective and ATP-competitive cell division cycle 7 kinase inhibitor (IC50: &lt;0.3 nM).</p>
    Fórmula:C17H19N5OS
    Pureza:99.93% - 99.93%
    Forma y color:Solid
    Peso molecular:341.43
  • Elarofiban TFA

    CAS:
    <p>Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.</p>
    Fórmula:C26H34F6N4O8
    Pureza:99.08%
    Forma y color:Soild
    Peso molecular:644.56
  • GSK-1520489A

    CAS:
    <p>GSK-1520489A is an active PKMYT1 inhibitor.</p>
    Fórmula:C21H23N5O3S
    Pureza:99.85%
    Forma y color:Solid
    Peso molecular:425.5
  • Abrilumab

    CAS:
    <p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>
    Pureza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)
    Forma y color:Liquid
  • Ceftriaxone sodium hydrate

    CAS:
    <p>Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.</p>
    Fórmula:C18H16N8Na2O7S3·5H2O
    Pureza:99.77% - 99.78%
    Forma y color:White Or Almost White Crystalline Powder Odorless
    Peso molecular:661.6
  • Cyclin K degrader 1


    <p>Cyclin K degrader 1 is a Cyclin K degrader.Cyclin K degrader 1 is a degrader converted from AT-7519.Cyclin K degrader 1 has weak degrading activity against Cyclin K but does not result in a sustained decrease in degradation affinity.Cyclin K degrader 1 is a degrader converted from AT-7519.</p>
    Fórmula:C23H17Cl2N5O2
    Pureza:99.76%
    Forma y color:Solid
    Peso molecular:466.32
  • NU6140

    CAS:
    <p>NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).</p>
    Fórmula:C23H30N6O2
    Pureza:98.33%
    Forma y color:Solid
    Peso molecular:422.52
  • Gemifloxacin mesylate

    CAS:
    <p>Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually</p>
    Fórmula:C19H24FN5O7S
    Pureza:97.24% - ≥95%
    Forma y color:Beige Solid
    Peso molecular:485.49
  • hSMG-1 inhibitor 11j

    CAS:
    <p>hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, &gt;455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.</p>
    Fórmula:C27H28ClN7O3S
    Pureza:99.22% - 99.65%
    Forma y color:Solid
    Peso molecular:566.07
  • LY 345899

    CAS:
    <p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>
    Fórmula:C20H21N7O7
    Pureza:99.7%
    Forma y color:Solid
    Peso molecular:471.42
  • BT173

    CAS:
    <p>BT173 is a novel inhibitor of homeodomain interacting protein kinase 2 (HIPK2 ), attenuating renal fibrosis through suppression of the TGF-ß1/Smad3 pathway.</p>
    Fórmula:C18H12BrN3O2
    Pureza:98.247%
    Forma y color:Solid
    Peso molecular:382.21
  • TAO Kinase inhibitor 2

    CAS:
    <p>TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.</p>
    Fórmula:C25H24N2O3
    Pureza:98.58%
    Forma y color:Soild
    Peso molecular:400.47
  • Avotaciclib

    CAS:
    <p>Avotaciclib (BEY1107) is a potent and orally active cyclin dependent kinase 1 (CDK1) inhibitor.Avotaciclib can be used to study locally advanced or metastatic</p>
    Fórmula:C13H11N7O
    Pureza:98.02%
    Forma y color:Solid
    Peso molecular:281.27
  • Enrofloxacin

    CAS:
    <p>Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.</p>
    Fórmula:C19H22FN3O3
    Pureza:99.43% - >99.99%
    Forma y color:Pale Yellow Crystals
    Peso molecular:359.39
  • Trilaciclib hydrochloride

    CAS:
    <p>Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).</p>
    Fórmula:C24H32Cl2N8O
    Pureza:99.69% - 99.89%
    Forma y color:Solid
    Peso molecular:519.47
  • Lerociclib dihydrochloride

    CAS:
    <p>Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/</p>
    Fórmula:C26H36Cl2N8O
    Pureza:97.4%
    Forma y color:Solid
    Peso molecular:547.52
  • Hycanthone

    CAS:
    <p>Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.</p>
    Fórmula:C20H24N2O2S
    Pureza:98.78%
    Forma y color:Yellow-Orange Powder (Ntp 1992)
    Peso molecular:356.48
  • Carmofur

    CAS:
    <p>Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.</p>
    Fórmula:C11H16FN3O3
    Pureza:98.53% - 99.98%
    Forma y color:Solid
    Peso molecular:257.26
  • TAK-901

    CAS:
    <p>TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others</p>
    Fórmula:C28H32N4O3S
    Pureza:99.02% - 99.59%
    Forma y color:Solid
    Peso molecular:504.64
  • SU056

    CAS:
    <p>SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.</p>
    Fórmula:C20H16FNO5
    Pureza:99.89%
    Forma y color:Soild
    Peso molecular:369.34
  • MYCi975

    CAS:
    <p>MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.</p>
    Fórmula:C25H16Cl2F6N2O2
    Pureza:99.3% - 99.82%
    Forma y color:Solid
    Peso molecular:561.3
  • Vitamin D2

    CAS:
    <p>Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.</p>
    Fórmula:C28H44O
    Pureza:98.73% - 99.89%
    Forma y color:Prisms From Acetone 1998)
    Peso molecular:396.65
  • R-10015

    CAS:
    <p>R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.</p>
    Fórmula:C20H19ClN6O2
    Pureza:98.68%
    Forma y color:Solid
    Peso molecular:410.86
  • Abciximab

    CAS:
    <p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>
    Pureza:SDS-PAGE:95.2%;SEC-HPLC:95.9%
    Forma y color:Liquid
    Peso molecular:95.18 kDa
  • Efalizumab

    CAS:
    <p>Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.</p>
    Pureza:SDS-PAGE:95% SEC-HPLC:98.77%
    Forma y color:Liquid
    Peso molecular:146.14 kDa
  • Cirtuvivint

    CAS:
    <p>Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.</p>
    Fórmula:C24H25N7O
    Pureza:99.46% - >99.99%
    Forma y color:Solid
    Peso molecular:427.5
  • Centrinone

    CAS:
    <p>Centrinone (LCR-263) (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4; Ki:0.16 nM).</p>
    Fórmula:C26H25F2N7O6S2
    Pureza:98.76%
    Forma y color:Solid
    Peso molecular:633.65
  • Paprotrain

    CAS:
    <p>Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.</p>
    Fórmula:C16H11N3
    Pureza:99.91%
    Forma y color:Solid
    Peso molecular:245.28
  • XPW1

    CAS:
    <p>XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.</p>
    Fórmula:C36H39ClFN7O2
    Pureza:98.08%
    Forma y color:Soild
    Peso molecular:656.19
  • DI-87

    CAS:
    <p>DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.</p>
    Fórmula:C23H30N6O3S2
    Pureza:99.76%
    Forma y color:Solid
    Peso molecular:502.65
  • 6-Mercaptopurine

    CAS:
    <p>6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.</p>
    Fórmula:C5H4N4S
    Pureza:99.53% - 99.63%
    Forma y color:Yellow Crystalline Powder Solid
    Peso molecular:152.18
  • Metarrestin

    CAS:
    <p>Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.</p>
    Fórmula:C31H30N4O
    Pureza:99.45%
    Forma y color:Solid
    Peso molecular:474.6
  • N-Dodecyl-β-D-maltoside

    CAS:
    <p>N-Dodecyl-β-D-maltoside (Lauryl Maltoside) has also been employed in applications such as in the purification and stabilization of RNA polymerase and the</p>
    Fórmula:C24H46O11
    Pureza:99.7% - >99.99%
    Forma y color:White Powder
    Peso molecular:510.62
  • MALAT1-IN-1

    CAS:
    <p>MALAT1-IN-1 is an effective dose-dependent Malat1 inhibitor, not altering Neat1 expression.</p>
    Fórmula:C19H21N3O2
    Pureza:99.58%
    Forma y color:Solid
    Peso molecular:323.39
  • CDK2-IN-4

    CAS:
    <p>CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.</p>
    Fórmula:C23H18N6O2S
    Pureza:97.24% - 99.10%
    Forma y color:Solid
    Peso molecular:442.49
  • Ribavirin

    CAS:
    <p>Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.</p>
    Fórmula:C8H12N4O5
    Pureza:99.09% - 99.83%
    Forma y color:Less Solid Colourless Solid
    Peso molecular:244.20
  • Famciclovir

    CAS:
    <p>Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.</p>
    Fórmula:C14H19N5O4
    Pureza:99.85%
    Forma y color:Off-White Powder
    Peso molecular:321.33
  • N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine


    <p>N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.</p>
    Fórmula:C41H43N3O9
    Forma y color:Solid
    Peso molecular:721.79
  • Clofarabine-5'-triphosphate

    CAS:
    <p>Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.</p>
    Fórmula:C10H14ClFN5O12P3
    Forma y color:Solid
    Peso molecular:543.62
  • Erythromycin thiocyanate

    CAS:
    <p>Erythromycin thiocyanate, a macrolide from Streptomyces erythreus, binds 50S ribosomes, halting protein synthesis in bacteria.</p>
    Fórmula:C38H68N2O13S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:793.02