Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(120 productos)
- CDK(561 productos)
- Detención del ciclo celular(8 productos)
- Chk(49 productos)
- DYRK(47 productos)
- Dynamin(28 productos)
- Ferroptosis(229 productos)
- HSP(184 productos)
- Integrin(288 productos)
- Kinesina(88 productos)
- LIM quinasa(22 productos)
- Asociado a microtúbulos(286 productos)
- PKC(130 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(7 productos)
- Wee1(19 productos)
- c-Myc(80 productos)
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Se han encontrado 2894 productos para "Ciclo celular / Checkpoint".
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(E/Z)-THZ1 2HCl
CAS:THZ1 2HCl: selective CDK7 allosteric inhibitor, IC50 3.2 nM, hinders cancer cell growth.Fórmula:C31H30Cl3N7O2Pureza:99.51%Forma y color:SolidPeso molecular:638.98Ceftriaxone sodium hydrate
CAS:Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.Fórmula:C18H16N8Na2O7S3·5H2OPureza:99.77% - 99.78%Forma y color:SolidPeso molecular:661.60Rifaximin
CAS:Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.Fórmula:C43H51N3O11Pureza:99.18% - 99.40%Forma y color:SolidPeso molecular:785.88hSMG-1 inhibitor 11j
CAS:hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, >455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.Fórmula:C27H28ClN7O3SPureza:99.22% - 99.65%Forma y color:Yellow SolidPeso molecular:566.07Metarrestin
CAS:Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.Fórmula:C31H30N4OPureza:99.45%Forma y color:White SolidPeso molecular:474.6Ref: TM-T12006
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)87,00€10mg137,00€25mg281,00€50mg485,00€100mg700,00€500mg1.459,00€Levofloxacin hydrate
CAS:Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Fórmula:C18H20FN3O4H2OPureza:98.26%Forma y color:White SolidPeso molecular:370.38CDK2-IN-4
CAS:CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.Fórmula:C23H18N6O2SPureza:97.24% - 99.10%Forma y color:SolidPeso molecular:442.49Ref: TM-T14916
1mg82,00€5mg192,00€1mL*10mM (DMSO)212,00€10mg304,00€25mg522,00€50mg713,00€100mg1.018,00€TAO Kinase inhibitor 2
CAS:TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.Fórmula:C25H24N2O3Pureza:98.58%Forma y color:SolidPeso molecular:400.47SU056
CAS:SU056 is a YB-1 inhibitor that induces cell-cycle arrest, apoptosis, and inhibits ovarian cancer cell migration.Fórmula:C20H16FNO5Pureza:99.89%Forma y color:Yellow SolidPeso molecular:369.34K34c hydrochloride
CAS:K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.Fórmula:C26H30ClN3O4Pureza:99.76% - 99.89%Forma y color:White SolidPeso molecular:483.99GSK-1520489A
CAS:GSK-1520489A is an active PKMYT1 inhibitor.Fórmula:C21H23N5O3SPureza:99.85%Forma y color:White SolidPeso molecular:425.5Ribociclib succinate
CAS:Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).Fórmula:C27H36N8O5Pureza:99.90%Forma y color:White SolidPeso molecular:552.63Ref: TM-T15732
2mg34,00€5mg49,00€1mL*10mM (DMSO)60,00€10mg70,00€25mg92,00€50mg109,00€100mg165,00€200mg258,00€500mg459,00€JH-RE-06
CAS:JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.Fórmula:C20H16Cl3N3O4Pureza:99.29%Forma y color:SolidPeso molecular:468.72Nedaplatin
CAS:Nedaplatin, a cisplatin derivative, induces tumor DNA damage (IC50: 94 μM) through platinum-DNA cross-links, causing apoptosis.Fórmula:C2H8N2O3PtPureza:99.88% - >99.99%Forma y color:SolidPeso molecular:303.17Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Fórmula:C26H31N7O4SPureza:99.25%Forma y color:SolidPeso molecular:537.63Ref: TM-T16130
2mg34,00€5mg54,00€1mL*10mM (DMSO)64,00€10mg87,00€25mg149,00€50mg255,00€100mg384,00€200mg538,00€BMT-124110 Formate
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinaseFórmula:C22H20N2O2Pureza:98.62%Forma y color:White SolidPeso molecular:344.41Ref: TM-T10572L
1mg175,00€5mg388,00€1mL*10mM (DMSO)404,00€10mg572,00€25mg888,00€50mg1.224,00€100mg1.648,00€500mg3.312,00€NU6140
CAS:NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).Fórmula:C23H30N6O2Pureza:98.33%Forma y color:SolidPeso molecular:422.52Ref: TM-T16359
2mg39,00€5mg60,00€1mL*10mM (DMSO)67,00€10mg92,00€25mg177,00€50mg285,00€100mg414,00€200mg580,00€Hycanthone
CAS:Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.Fórmula:C20H24N2O2SPureza:98.78%Forma y color:Yellow-Orange Powder (Ntp 1992)Peso molecular:356.48R-10015
CAS:R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.Fórmula:C20H19ClN6O2Pureza:98.68%Forma y color:SolidPeso molecular:410.86Ref: TM-T12609
1mg50,00€5mg112,00€1mL*10mM (DMSO)124,00€10mg170,00€25mg280,00€50mg371,00€100mg525,00€200mg712,00€PTBP1-RNA-binding inhibitor P6 TFA
PTBP1-RNA-binding inhibitor P6 TFA is a stapled peptide inhibitor of PTBP1, used to inhibit RNA alternative splicing events regulated by PTBP1.Forma y color:Odour Solid
