Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(126 productos)
- CDK(578 productos)
- Detención del ciclo celular(8 productos)
- Chk(50 productos)
- DYRK(47 productos)
- Dynamin(28 productos)
- Ferroptosis(239 productos)
- HSP(200 productos)
- Integrin(296 productos)
- Kinesina(89 productos)
- LIM quinasa(23 productos)
- Asociado a microtúbulos(303 productos)
- PKC(129 productos)
- PLK(29 productos)
- ROCK(66 productos)
- Rho(7 productos)
- Wee1(20 productos)
- c-Myc(83 productos)
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Se han encontrado 2897 productos para "Ciclo celular / Checkpoint".
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Rifaximin
CAS:Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.Fórmula:C43H51N3O11Pureza:99.18% - 99.40%Forma y color:SolidPeso molecular:785.8785hSMG-1 inhibitor 11j
CAS:hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, >455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.Fórmula:C27H28ClN7O3SPureza:99.22% - 99.69%Forma y color:Yellow SolidPeso molecular:566.074Fuzapladib
CAS:Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.Fórmula:C15H20F3N3O3SPureza:99.87%Forma y color:SolidPeso molecular:379.398Levofloxacin hydrate
CAS:Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Fórmula:C18H20FN3O4H2OPureza:98.26%Forma y color:White SolidPeso molecular:370.38CDK2-IN-4
CAS:CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.Fórmula:C23H18N6O2SPureza:97.24% - 99.10%Forma y color:SolidPeso molecular:442.493TAO Kinase inhibitor 2
CAS:TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.Fórmula:C25H24N2O3Pureza:98.58%Forma y color:SolidPeso molecular:400.4697Metarrestin
CAS:Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.Fórmula:C31H30N4OPureza:99.45%Forma y color:White SolidPeso molecular:474.5961Ribociclib succinate
CAS:Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).Fórmula:C27H36N8O5Pureza:99.90%Forma y color:White SolidPeso molecular:552.6253Carmofur
CAS:Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.Fórmula:C11H16FN3O3Pureza:98.53% - 99.98%Forma y color:SolidPeso molecular:257.2614Hu7691 free base
CAS:Hu7691 free base is an Akt inhibitor that inhibits Akt1, Akt2 and Akt3 and induces differentiation of neuroblastoma cells.Fórmula:C22H21F3N4OPureza:98.89%Forma y color:SolidPeso molecular:414.423R-10015
CAS:R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.Fórmula:C20H19ClN6O2Pureza:98.68%Forma y color:SolidPeso molecular:410.857MKC8866
CAS:MKC8866, a selective IRE1 RNase inhibitor with an IC50 of 0.29 μM, curbs breast and prostate cancer cell growth.Fórmula:C18H19NO7Pureza:99.28% - 99.91%Forma y color:Yellow SolidPeso molecular:361.346Hycanthone
CAS:Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.Fórmula:C20H24N2O2SPureza:98.78%Forma y color:Yellow-Orange Powder (Ntp 1992)Peso molecular:356.482TK216
CAS:TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.Fórmula:C19H15Cl2NO3Pureza:97.22%Forma y color:SolidPeso molecular:376.233JH-RE-06
CAS:JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.Fórmula:C20H16Cl3N3O4Pureza:99.29%Forma y color:SolidPeso molecular:468.718BAY-524
CAS:BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP).Fórmula:C24H24F2N6O3Pureza:98.68% - 99.57%Forma y color:White SolidPeso molecular:482.4826Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Fórmula:C26H31N7O4SPureza:99.25%Forma y color:SolidPeso molecular:537.634N-Dodecyl-β-D-maltoside
CAS:N-Dodecyl-β-D-maltoside (Lauryl Maltoside) has also been employed in applications such as in the purification and stabilization of RNA polymerase and theFórmula:C24H46O11Pureza:99.18% - >99.99%Forma y color:White PowderPeso molecular:510.62GSK-1520489A
CAS:GSK-1520489A is an active PKMYT1 inhibitor.Fórmula:C21H23N5O3SPureza:99.85%Forma y color:White SolidPeso molecular:425.5GSK-3 inhibitor 4
CAS:Orally active GSK-3 inhibitor 4 targets GSK-3α/β, CDK2/5 (IC50: 0.45-0.68 μM) and may aid in Alzheimer's research by lowering Tau protein.Fórmula:C22H15F2N5OPureza:99.82%Forma y color:SolidPeso molecular:403.38
