Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(120 productos)
- CDK(561 productos)
- Detención del ciclo celular(8 productos)
- Chk(49 productos)
- DYRK(47 productos)
- Dynamin(28 productos)
- Ferroptosis(229 productos)
- HSP(184 productos)
- Integrin(288 productos)
- Kinesina(88 productos)
- LIM quinasa(22 productos)
- Asociado a microtúbulos(286 productos)
- PKC(130 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(7 productos)
- Wee1(19 productos)
- c-Myc(80 productos)
Mostrar 10 subcategorías más
Se han encontrado 2894 productos para "Ciclo celular / Checkpoint".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
DNA2 inhibitor C5
CAS:DNA2 inhibitor C5 is a specific cancer sensitizer with an IC50 of 20 μM, targeting multiple DNA2 activities.Fórmula:C10H6N2O5Pureza:99.05%Forma y color:SolidPeso molecular:234.16Ref: TM-T15146
1mg57,00€1mL*10mM (DMSO)112,00€5mg113,00€10mg178,00€25mg334,00€50mg497,00€100mg692,00€RWJ 50271
CAS:RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Fórmula:C18H17F3N4O2SPureza:99.09%Forma y color:White SolidPeso molecular:410.41Ref: TM-T12783
1mg120,00€5mg295,00€1mL*10mM (DMSO)326,00€10mg447,00€25mg707,00€50mg964,00€100mg1.243,00€200mg1.693,00€Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Fórmula:C32H47N5O6SPureza:99.41%Forma y color:White SolidPeso molecular:629.81Ref: TM-T13257
1mg60,00€2mg89,00€5mg138,00€1mL*10mM (DMSO)155,00€10mg215,00€25mg359,00€50mg510,00€100mg692,00€BRD6989
CAS:BRD6989, a cortistatin A analog, inhibits CDK8/19, enhances IL-10, and binds CDK8 with a 200 nM IC50.Fórmula:C16H16N4Pureza:99.43%Forma y color:SolidPeso molecular:264.33Ref: TM-T14778
1mg34,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg92,00€25mg177,00€50mg268,00€100mg398,00€200mg575,00€DHODH-IN-11
CAS:DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.Fórmula:C15H11N3O2Pureza:98.14%Forma y color:SolidPeso molecular:265.27Pyrimethamine
CAS:Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.Fórmula:C12H13ClN4Pureza:99.67%Forma y color:CrystalsPeso molecular:248.71CDK8-IN-12
CAS:CDK8-IN-12: selective CDK8 inhibitor (Ki 14 nM), oral anticancer, blocks GSK-3α/β, PCK-θ, halts MV4-11 cell growth.Fórmula:C21H20ClN3O2Pureza:98.55% - 99.22%Forma y color:SoildPeso molecular:381.86Ref: TM-T72048
1mg49,00€5mg96,00€1mL*10mM (DMSO)110,00€10mg142,00€25mg236,00€50mg344,00€100mg482,00€200mg658,00€Lerociclib dihydrochloride
CAS:Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/Fórmula:C26H36Cl2N8OPureza:97.4%Forma y color:SolidPeso molecular:547.52Carmofur
CAS:Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.Fórmula:C11H16FN3O3Pureza:98.53% - 99.98%Forma y color:SolidPeso molecular:257.26Orbofiban TFA
CAS:Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFórmula:C19H24F3N5O6Pureza:97.21% - 99.23%Forma y color:SolidPeso molecular:475.42Trimethoprim
CAS:Trimethoprim (NSC-106568) inhibits dihydrofolate reductase, CYP2C8, and OCT2 - an antibacterial agent.Fórmula:C14H18N4O3Pureza:99.80% - 99.81%Forma y color:SolidPeso molecular:290.32BAY-524
CAS:BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP).Fórmula:C24H24F2N6O3Pureza:98.68% - 99.57%Forma y color:White SolidPeso molecular:482.48Ref: TM-T14505
1mg96,00€5mg177,00€1mL*10mM (DMSO)178,00€10mg298,00€25mg482,00€50mg658,00€100mg892,00€Pazufloxacin Mesylate
CAS:Pazufloxacin Mesylate (T-3762) is a fluoroquinolone antibiotic.Fórmula:C16H15FN2O4·CH4O3SPureza:99.88% - 99.93%Forma y color:SolidPeso molecular:414.4ZN-c3
CAS:Azenosertib (ZN-c3) is a potent and selective Wee1 inhibitor with balanced potency, ADME, and pharmacokinetic properties. Cost-effective and quality-assured.Fórmula:C29H34N8O2Pureza:99.98%Forma y color:SolidPeso molecular:526.63Ref: TM-T9643
1mg90,00€5mg215,00€1mL*10mM (DMSO)250,00€10mg334,00€25mg620,00€50mg982,00€100mg1.468,00€200mg1.972,00€Ca2+ channel agonist 1
CAS:Ca2+ channel agonist 1 activates N-type Ca2+ channels and inhibits Cdk2 (EC50: 14.23 μM/3.34 μM) for motor nerve issues.Fórmula:C19H26N6OPureza:97.71%Forma y color:SolidPeso molecular:354.45Ref: TM-T10659
1mg92,00€5mg178,00€1mL*10mM (DMSO)207,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.071,00€Tinengotinib
CAS:Tinengotinib is a multikinase inhibitor that targets a series of kinases , including Aurora kinases A/B, JAK1/2, FGFR1/2/3, VEGFRs, and many other kinases.Fórmula:C20H19ClN6OPureza:99.05%Forma y color:SolidPeso molecular:394.86Famciclovir
CAS:Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.Fórmula:C14H19N5O4Pureza:99.85% - 99.99%Forma y color:White SolidPeso molecular:321.33Arg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Fórmula:C17H31N7O10Pureza:99.92%Forma y color:SolidPeso molecular:493.47Osalmid
CAS:Osalmid (Oxaphenamide) is a choleretic drug, inhibits ribonucleotide reductase activity by targeting ribonucleotide reductase small subunit M2 (RRM2).Fórmula:C13H11NO3Pureza:99.37% - 99.6%Forma y color:SolidPeso molecular:229.23ATN-161 acetate
CAS:ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Fórmula:C25H39N9O10SPureza:98.27%Forma y color:White SolidPeso molecular:657.7
