Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(939 produtos)
- ACK(1 produtos)
- AChR(575 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.945 produtos)
- BACE(36 produtos)
- Beta Amilóide(205 produtos)
- CaMK(69 produtos)
- COX(561 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5400 produtos de "Neurociência"
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Pridinol hydrochloride
CAS:<p>Pridinolhydrochloride is the hydrochloride form of Pridinol. Pridinol hydrochloride is an orally active anticholinergic agent, which can also be used as a muscle relaxant.</p>Fórmula:C20H26ClNOCor e Forma:SolidPeso molecular:331.88Lu AF27139
CAS:<p>Lu AF27139: P2X7 receptor antagonist; IC50: 12 nM (human), 2.4 nM (rat); Ki: 22 (mouse), 54 (human), 13 nM (rat); for CNS research.</p>Fórmula:C21H19ClF3N5O2SPureza:99.96%Cor e Forma:SolidPeso molecular:497.92AChE/BuChE-IN-4
CAS:<p>AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.</p>Fórmula:C17H23N5Pureza:99.89%Cor e Forma:SoildPeso molecular:297.4NMDA receptor antagonist 6
<p>NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotective</p>Fórmula:C25H23NO2Pureza:98%Cor e Forma:SolidPeso molecular:369.46γ-DGG TFA
CAS:<p>Gamma-DGG TFA is an antagonist of excitatory amino acids that can inhibit depolarization induced by NMDA, Kainate, and Quisqualate. In addition, it counteracts excitatory postsynaptic potentials (e.p.s.p.) in rat hippocampal slices.</p>Fórmula:C9H13F3N2O7Cor e Forma:SolidPeso molecular:318.24-hydroxy DiPT hydrochloride
CAS:<p>4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.</p>Fórmula:C16H25ClN2OCor e Forma:SolidPeso molecular:296.84Cinazepam
CAS:<p>Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.</p>Fórmula:C19H14BrClN2O5Cor e Forma:SolidPeso molecular:465.682,6-DMA hydrochloride
CAS:<p>2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.</p>Fórmula:C11H18ClNO2Cor e Forma:SolidPeso molecular:231.72BIMU 8
CAS:<p>BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.</p>Fórmula:C19H27ClN4O2Pureza:99.87%Cor e Forma:SolidPeso molecular:378.9Lysyl hydroxylase 2-IN-2
<p>Lysyl Hydroxylase 2-IN-2 (compound 13) is a potent inhibitor of Lysyl Hydroxylase 2 (LH2), exhibiting an IC50 of approximately 500 nM.</p>Fórmula:C19H21N3O2Pureza:98%Cor e Forma:SolidPeso molecular:323.39MmTx2 toxin
<p>MmTx2 toxin, extracted from the venom of the coral snake, serves as a modulator of the GABA A receptor, increasing its responsiveness to agonists.</p>Fórmula:C295H450N94O97S10Pureza:98%Cor e Forma:SolidPeso molecular:7185.95AChE/BChE-IN-25
<p>AChE/BChE-IN-25 (Compound 6e) is an orally active inhibitor of hAChE and eqBChE, with IC50 values of 7.9 nM and 0.79 nM, respectively. This compound exhibits antioxidant activity, effective in scavenging free radicals with an IC50 of 22.91 μM. AChE/BChE-IN-25 demonstrates neuroprotective effects by reducing mitochondrial and cellular oxidative stress in a Drosophila Alzheimer's model and improves spatial and cognitive memory impairments induced by Scopolamine in mouse models.</p>Fórmula:C21H24ClN3O2Cor e Forma:SolidPeso molecular:385.89Pyrazolam
CAS:<p>Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.</p>Fórmula:C16H12BrN5Cor e Forma:SolidPeso molecular:354.2COX-1/2-IN-5
<p>COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and</p>Fórmula:C21H22N2O5SPureza:98%Cor e Forma:SolidPeso molecular:414.47δ-secretase inhibitor 11
CAS:<p>δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.</p>Fórmula:C10H12N4O2Pureza:99.84%Cor e Forma:SolidPeso molecular:220.23TET-13
<p>TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.</p>Fórmula:C15H16N2O3SCor e Forma:SolidPeso molecular:304.36TB-11
CAS:<p>TB-11 is an inhibitor of Cathepsin D with IC50 values of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), and 48.8 nM (BACE1). It is primarily utilized in oncological research.</p>Fórmula:C52H78N8O12Cor e Forma:SolidPeso molecular:1007.22Org 13011
CAS:<p>Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.</p>Fórmula:C18H25F3N4OPureza:98.02%Cor e Forma:SoildPeso molecular:370.41(Iso)-Samixogrel
CAS:<p>(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.</p>Fórmula:C25H25ClN2O4SPureza:98.80%Cor e Forma:SolidPeso molecular:484.99(Rac)-Sabcomeline
CAS:<p>(Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.</p>Fórmula:C10H15N3OPureza:99.14%Cor e Forma:SolidPeso molecular:193.25Binospirone
CAS:<p>Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.</p>Fórmula:C20H26N2O4Pureza:97.57% - 98.96%Cor e Forma:SoildPeso molecular:358.43GAD65(247-266) epitope TFA
<p>GAD65(247-266) epitope TFA, a T cell epitope derived from islet antigens, exhibits competitive binding to the type I diabetes-associated molecule I-A g7, albeit</p>Fórmula:C111H174F3N27O29S4Pureza:98%Cor e Forma:SolidPeso molecular:2535.99(-)-2-Phenylpropylamine
CAS:<p>(-)-2-Phenylpropylamine ((S)-2-Phenylpropylamine) (compound 3b) functions as an inhibitor for both MAO-A and MAO-B, with Ki values of 584 μM and 156 μM, respectively.</p>Fórmula:C9H13NCor e Forma:SolidPeso molecular:135.21p-Xylene bis(pyridinium bromide)
CAS:<p>p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.</p>Fórmula:C18H18Br2N2Cor e Forma:SolidPeso molecular:422.16SB 258585
CAS:<p>SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.</p>Fórmula:C18H22IN3O3SPureza:99.8%Cor e Forma:SoildPeso molecular:487.36Argiotoxin 636
CAS:<p>Argiotoxin 636 is a toxin and serves as a non-specific, non-competitive, and effective antagonist of ionotropic glutamate receptors (iGluR). It inhibits excitatory synaptic transmission in neurons and has paralyzing and muscle relaxant effects. Argiotoxin 636 can be utilized for research in neurological disorders.</p>Fórmula:C29H52N10O6Cor e Forma:SolidPeso molecular:636.79Litoxetine HCl
<p>Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.</p>Fórmula:C16H20ClNOPureza:99.56% - 99.75%Cor e Forma:SoildPeso molecular:277.79Desfesoterodine
CAS:<p>Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.</p>Fórmula:C22H31NO2Pureza:99.77%Cor e Forma:SolidPeso molecular:341.49(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Fórmula:C10H10ClNO6Pureza:99.53% - 99.9%Cor e Forma:SoildPeso molecular:275.64MRS7925
<p>MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosis</p>Fórmula:C20H26IN5O3Pureza:98%Cor e Forma:SolidPeso molecular:511.36RS 56812
CAS:<p>RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.</p>Fórmula:C18H21N3O2Pureza:99.38%Cor e Forma:SoildPeso molecular:311.38AC3-I, myristoylated
<p>Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).</p>Fórmula:C78H137N21O20Pureza:98%Cor e Forma:SolidPeso molecular:1689.05Hydroxytacrine maleate
CAS:<p>Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase inhibitor used in the study of Alzheimer's type dementia (SDAT).</p>Fórmula:C17H18N2O5Pureza:98.84%Cor e Forma:SolidPeso molecular:330.34Tiquizium
CAS:<p>Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.</p>Fórmula:C19H24NS2Pureza:99.82%Cor e Forma:SolidPeso molecular:330.53Tropicamide
CAS:<p>Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.</p>Fórmula:C17H20N2O2Pureza:99.78% - 99.94%Cor e Forma:White PowderPeso molecular:284.35NMDAR antagonist 2
<p>NMDAR antagonist 2 (compound 3I) is a blood-brain barrier permeable antagonist of NMDA receptors, exhibiting IC50 values of 4.42 μM and 214.75 μM at membrane potentials of -60 mV and 40 mV, respectively, for hGluN1/hGluN2A. This compound has been shown to mitigate hippocampal damage.</p>Fórmula:C17H20ClNOCor e Forma:SolidPeso molecular:289.84-Iodoamphetamine hydrochloride
CAS:<p>4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.</p>Fórmula:C9H13ClINCor e Forma:SolidPeso molecular:297.56MAO-B-IN-25
<p>MAO-B-IN-25 (compound 92) is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting inhibitory half-maximal inhibitory concentrations (IC50) of 240 nM</p>Fórmula:C16H13BrO3Pureza:98%Cor e Forma:SolidPeso molecular:333.18MmTx1 toxin
<p>Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].</p>Fórmula:C295H455N95O97S10Pureza:98%Cor e Forma:SolidPeso molecular:7205CaMKIIα-PHOTAC
<p>CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).</p>Fórmula:C54H58Cl2N10O11Pureza:98%Cor e Forma:SolidPeso molecular:1094Methyllycaconitine citrate
CAS:<p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>Fórmula:C43H58N2O17Pureza:98.03% - 98.91%Cor e Forma:SolidPeso molecular:874.925-(2-Aminopropyl)indole
CAS:<p>5-(2-Aminopropyl)indole is an orally active psychoactive substance that inhibits monoamine oxidase (MAO) and exhibits long-lasting stimulant effects.</p>Fórmula:C11H14N2Cor e Forma:SolidPeso molecular:174.24IHC3
<p>IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.</p>Fórmula:C17H12FN3OPureza:98%Cor e Forma:SolidPeso molecular:293.3MAOA-IN-1
<p>MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.</p>Fórmula:C13H16Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:303.18BMS-906024
CAS:<p>BMS-906024 (Osugacestat) is a gamma secretase inhibitor, a Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity.</p>Fórmula:C26H26F6N4O3Pureza:99.88% - >99.99%Cor e Forma:SolidPeso molecular:556.5GABA receptor Antagonist 1
<p>GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.</p>Pureza:98%Cor e Forma:Odour SolidMethamnetamine hydrochloride
CAS:<p>Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.</p>Fórmula:C14H18ClNCor e Forma:SolidPeso molecular:235.75Adatanserin hydrochloride
CAS:<p>Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.</p>Fórmula:C21H32ClN5OPureza:99.64%Cor e Forma:SolidPeso molecular:405.96Trontinemab
CAS:<p>Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).</p>Pureza:96.77% - 99%Cor e Forma:Liquid5-AAM-2-CP
CAS:<p>5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.</p>Fórmula:C8H9ClN2OPureza:99.58%Cor e Forma:SolidPeso molecular:184.62MAO-B-IN-37
CAS:<p>MAO-B-IN-37 (Compound 37) is a derivative of TT01001 and acts as a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 270 nM. It exhibits good metabolic stability in mouse microsomes and shows strong affinity for human serum albumin.</p>Fórmula:C14H12FN3O3Cor e Forma:SolidPeso molecular:289.266-Fluoro-N,N-diethyltryptamine
CAS:<p>6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.</p>Fórmula:C14H19FN2Cor e Forma:SolidPeso molecular:234.315-HT6 agonist 1
Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting plateletFórmula:C17H22Cl2N6SPureza:98%Cor e Forma:SolidPeso molecular:413.3725E-NBOMe hydrochloride
CAS:<p>25E-NBOMe hydrochloride is a derivative of 2C-E, featuring an N-(2-methoxybenzyl) addition to the amine group, and acts as a selective agonist of the 5-HT2A receptor.</p>Fórmula:C20H28ClNO3Cor e Forma:SolidPeso molecular:365.89KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Fórmula:C22H12F3N5Na2O7Pureza:97.27%Cor e Forma:SoildPeso molecular:561.33Nemifitide diTFA
CAS:<p>Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.</p>Fórmula:C37H45F7N10O10Pureza:99.78% - 99.84%Cor e Forma:SolidPeso molecular:922.8Arotinolol hydrochloride
CAS:<p>Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.</p>Fórmula:C15H22ClN3O2S3Pureza:99.84%Cor e Forma:SolidPeso molecular:408Brexpiprazole S-oxide
CAS:<p>Brexpiprazole S-oxide is the main metabolite of Brexpiprazole, a human 5-HT1A and dopamine receptor partial agonist (Ki: 0.12, 0.3 nM).</p>Fórmula:C25H27N3O3SPureza:98%Cor e Forma:SolidPeso molecular:449.57Orexin B, human
CAS:<p>Orexin B, human agonizes Orexin receptors (OX1 Ki=420 nM, OX2 Ki=36 nM), promotes feeding in rats, and is a neuropeptide.</p>Fórmula:C123H212N44O35SPureza:98%Cor e Forma:SolidPeso molecular:2899.34Br-PBTC
CAS:<p>Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.</p>Fórmula:C14H15BrN2OSCor e Forma:SolidPeso molecular:339.25Mesoridazine Besylate
CAS:<p>Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.</p>Fórmula:C27H32N2O4S3Pureza:99.58%Cor e Forma:SolidPeso molecular:544.75α-Casozepine
CAS:<p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>Fórmula:C60H94N14O16Cor e Forma:SolidPeso molecular:1267.47Tiaspirone hydrochloride
CAS:<p>Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.</p>Fórmula:C24H33ClN4O2SPureza:99.87%Cor e Forma:SoildPeso molecular:477.06BuChE-IN-8
<p>BuChE-IN-8 (compound 19c), a butyrylcholinesterase (BuChE) inhibitor, exhibits an IC50 value of 559 nM and concurrently inhibits human β-secretase (BACE1) and</p>Fórmula:C28H33ClN4O2SCor e Forma:SolidPeso molecular:525.11DCCCyb
CAS:<p>DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.</p>Fórmula:C22H29Cl2NO3SPureza:98%Cor e Forma:SolidPeso molecular:458.44COX-2-IN-35
<p>COX-2-IN-35 (compound 7) is a selective inhibitor of COX-2, demonstrating anti-inflammatory activity, with an inhibitory concentration (IC 50) of 4.37 nM [1].</p>Fórmula:C22H19NO2S2Pureza:98%Cor e Forma:SolidPeso molecular:393.52(S,S)-BMS-984923
CAS:<p>(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.</p>Fórmula:C22H15ClN2O2Cor e Forma:SolidPeso molecular:374.82Triazolomethylindole-3-acetic acid
CAS:<p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>Fórmula:C13H12N4O2Cor e Forma:SolidPeso molecular:256.26CALP2 TFA
<p>CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.</p>Fórmula:C70H105F3N14O15SCor e Forma:SolidPeso molecular:1471.72β-Amyloid (13-27)
CAS:<p>β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.</p>Fórmula:C84H126N24O24Pureza:98%Cor e Forma:SolidPeso molecular:1856.05Cevimeline hydrochloride hemihydrate
CAS:<p>Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.</p>Fórmula:C20H38Cl2N2O3S2Pureza:97.00%Cor e Forma:SolidPeso molecular:489.55TAT-CN21
<p>TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.</p>Fórmula:C169H303N69O43Cor e Forma:SolidPeso molecular:3989.65Alosetron
CAS:<p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>Fórmula:C17H18N4OPureza:98%Cor e Forma:Crystalline PowderPeso molecular:294.36Asenapine citrate
CAS:<p>Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).</p>Fórmula:C23H24ClNO8Cor e Forma:SolidPeso molecular:477.89α-Conotoxin EI
CAS:<p>Selective antagonist of neuromuscular nicotinic receptors α1β1γδ</p>Fórmula:C83H125N27O27S5Pureza:98%Cor e Forma:SolidPeso molecular:2093.37Cytidine 5′-diphosphoethanolamine
CAS:<p>Cytidine 5′-diphosphoethanolamine, a key intermediate in phosphatidylethanolamine synthesis, also serves as a stimulant of Ach synthesis [1].</p>Fórmula:C11H20N4O11P2Cor e Forma:SolidPeso molecular:446.24BuChE-IN-16
<p>BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.</p>Fórmula:C16H22N2O3Cor e Forma:SolidPeso molecular:290.36β-Amyloid (1-16)
CAS:<p>β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.</p>Fórmula:C84H119N27O28Pureza:98%Cor e Forma:SolidPeso molecular:1955.04AChE-IN-43
<p>AChE-IN-43 is a potent, selective AChE inhibitor with a K i of 0.41 μM, applicable in the study of neurological diseases [1].</p>Cor e Forma:Odour SolidCisapride hydrate
CAS:<p>Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of 0.483 μM. And It also acts indirectly as a parasympathomimetic.</p>Fórmula:C23H31ClFN3O5Pureza:98%Cor e Forma:SolidPeso molecular:483.96Tranylcypromine
CAS:<p>Tranylcypromine (SKF 385), a potent monoamine oxidase (MAO) inhibitor [1], is used in medicinal applications.</p>Fórmula:C9H11NPureza:98%Cor e Forma:SolidPeso molecular:133.19β-Amyloid (29-40)
CAS:<p>β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties</p>Fórmula:C49H88N12O13SPureza:98%Cor e Forma:SolidPeso molecular:1085.36(Met(O2)35)-Amyloid β-Protein (1-42)
<p>(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .</p>Fórmula:C203H311N55O62SCor e Forma:SolidPeso molecular:4546.04[Ala11,D-Leu15]-Orexin B acetate
<p>[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).</p>Fórmula:C122H210N44O37SPureza:98.18%Cor e Forma:SolidPeso molecular:2917.31hAChE/hBuChE-IN-1
<p>hAChE/hBuChE-IN-1 (compound C2) acts as a dual inhibitor of cholinesterases, exhibiting IC50 values of 514 nM for hAChE and 358 nM for hBuChE. It is orally active and capable of enhancing cognitive function and spatial memory.</p>Fórmula:C30H31FN2O3Cor e Forma:SolidPeso molecular:486.577AC1-IN-1
CAS:<p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>Fórmula:C18H18FN5O2Pureza:99.89%Cor e Forma:SolidPeso molecular:355.37CPN-267 TFA
<p>CPN-267 (compound 7b) TFA is a selective agonist of neuromedin U receptor 1 (NMUR1) with an EC50 of 0.25 nM. This compound inhibits weight gain in mice and is applicable in obesity research.</p>Fórmula:C54H68F6N16O12SCor e Forma:SolidPeso molecular:1279.27β-Amyloid (22-35)
CAS:<p>β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.</p>Fórmula:C59H102N16O21SPureza:98%Cor e Forma:SolidPeso molecular:1403.62TC-2216
CAS:<p>TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.</p>Fórmula:C12H17N3Pureza:99.33%Cor e Forma:SolidPeso molecular:203.28FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
<p>FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.</p>Fórmula:C227H330N58O66S2Cor e Forma:SolidPeso molecular:4991.53Bencycloquidium Bromide
CAS:<p>Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.</p>Fórmula:C21H32BrNO2Cor e Forma:SolidPeso molecular:410.39β-Amyloid (1-38), mouse, rat
CAS:<p>β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.</p>Cor e Forma:SolidProfenofos
CAS:<p>Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.</p>Fórmula:C11H15BrClO3PSPureza:97.04% - 97.24%Cor e Forma:SolidPeso molecular:373.63OM99-2
CAS:<p>OM99-2, an 8-residue peptidomimetic, binds memapsin 2 with 9.58 nM Ki; promising for Alzheimer's research.</p>Fórmula:C41H64N8O14Cor e Forma:SolidPeso molecular:893.005Galanin (1-15) (porcine, rat)
CAS:<p>N-terminal galanin fragment used to mediate central cardiovascular effects</p>Fórmula:C72H105N19O20Pureza:98%Cor e Forma:SolidPeso molecular:1556.724-Hydroxy MPT
CAS:<p>4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.</p>Fórmula:C14H20N2OCor e Forma:SolidPeso molecular:232.32BuChE-IN-13
<p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>Cor e Forma:Odour Solid(Met(O)35)-Amyloid β-Protein (1-42)
<p>(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of</p>Fórmula:C203H311N55O61SCor e Forma:SolidPeso molecular:4530.04Biotin-β-Amyloid (1-42), human TFA
<p>Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the</p>Fórmula:C215H326F3N57O64S2Cor e Forma:SolidPeso molecular:4854.365-HT2A receptor agonist-6
CAS:<p>5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.</p>Fórmula:C18H19N3O3Cor e Forma:SolidPeso molecular:325.36
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