Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(939 produtos)
- ACK(1 produtos)
- AChR(575 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.945 produtos)
- BACE(36 produtos)
- Beta Amilóide(205 produtos)
- CaMK(69 produtos)
- COX(561 produtos)
- Receptor de Dopamina(407 produtos)
- Receptor GABA(336 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(358 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(28 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(297 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5400 produtos de "Neurociência"
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6,7-dimethylisatin
CAS:<p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>Fórmula:C10H9NO2Pureza:98.98%Cor e Forma:SolidPeso molecular:175.18MmTx1 toxin
<p>Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].</p>Fórmula:C295H455N95O97S10Pureza:98%Cor e Forma:SolidPeso molecular:7205CaMKIIα-PHOTAC
<p>CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).</p>Fórmula:C54H58Cl2N10O11Pureza:98%Cor e Forma:SolidPeso molecular:1094Calmodulin Kinase IINtide, Myristoylated
<p>Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].</p>Fórmula:C156H275N47O43Pureza:98%Cor e Forma:SolidPeso molecular:3497.14Anti-inflammatory agent 52
<p>Anti-inflammatory agent 52 (compound 7j) is an orally active, selective COX-2 inhibitor with the capability to induce G2/M phase arrest and exhibit anti-HT29</p>Fórmula:C24H21ClN2O3SPureza:98%Cor e Forma:SolidPeso molecular:452.95COX-2-IN-31
<p>COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 μM).</p>Fórmula:C17H16N6O4SPureza:98%Cor e Forma:SolidPeso molecular:400.41PZ-1922
<p>PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.</p>Pureza:98%Cor e Forma:Odour SolidAC 253
CAS:<p>Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.</p>Fórmula:C122H196N40O39Pureza:98%Cor e Forma:SolidPeso molecular:2847.11MmTx2 toxin
<p>MmTx2 toxin, extracted from the venom of the coral snake, serves as a modulator of the GABA A receptor, increasing its responsiveness to agonists.</p>Fórmula:C295H450N94O97S10Pureza:98%Cor e Forma:SolidPeso molecular:7185.95Lysyl hydroxylase 2-IN-2
<p>Lysyl Hydroxylase 2-IN-2 (compound 13) is a potent inhibitor of Lysyl Hydroxylase 2 (LH2), exhibiting an IC50 of approximately 500 nM.</p>Fórmula:C19H21N3O2Pureza:98%Cor e Forma:SolidPeso molecular:323.39NMDA receptor antagonist 6
<p>NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotective</p>Fórmula:C25H23NO2Pureza:98%Cor e Forma:SolidPeso molecular:369.46nAChR agonist CMPI hydrochloride
CAS:<p>CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.</p>Fórmula:C18H20Cl2N4OCor e Forma:SolidPeso molecular:379.29γ-Secretase modulator 10
CAS:<p>γ-Secretase modulator 10 is a novel γ-secretase modulator.</p>Fórmula:C25H23F3N4O2Cor e Forma:SolidPeso molecular:468.48BChE-IN-10
CAS:<p>BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.</p>Fórmula:C23H20O5Cor e Forma:SolidPeso molecular:376.4MGS0274
CAS:<p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>Fórmula:C21H32FNO7Cor e Forma:SolidPeso molecular:429.485Echimidine N-oxide
CAS:<p>Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.</p>Fórmula:C20H31NO8Cor e Forma:SolidPeso molecular:413.467Dicloromezotiaz
CAS:<p>Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.</p>Fórmula:C19H12Cl3N3O2SCor e Forma:SolidPeso molecular:452.745-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Fórmula:C25H30N4O2SCor e Forma:SolidPeso molecular:450.6YS-370
CAS:<p>YS-370 orally blocks P-gp, moderately inhibits CYP3A4, reverses drug resistance, and enhances paclitaxel's anticancer effects.</p>Fórmula:C37H35BrN4O3Pureza:98.055%Cor e Forma:SolidPeso molecular:663.6TC-2216
CAS:<p>TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.</p>Fórmula:C12H17N3Pureza:99.33%Cor e Forma:SolidPeso molecular:203.28nAChR agonist 2
CAS:<p>Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,</p>Fórmula:C11H16N2Cor e Forma:SolidPeso molecular:176.263DOPR hydrochloride
CAS:<p>DOPR hydrochloride is a psychoactive substance belonging to the amphetamine class.</p>Fórmula:C14H24ClNO2Cor e Forma:SolidPeso molecular:273.84-Bromo-2,5-DMMA
CAS:<p>4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.</p>Fórmula:C12H18BrNO2Cor e Forma:SolidPeso molecular:288.18Desalkylgidazepam
CAS:<p>Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).</p>Fórmula:C15H11BrN2OCor e Forma:SolidPeso molecular:315.1725N-NBOMe hydrochloride
CAS:<p>25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.</p>Fórmula:C18H23ClN2O5Cor e Forma:SolidPeso molecular:382.845-MeO-MET
CAS:<p>5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.</p>Fórmula:C14H20N2OCor e Forma:SolidPeso molecular:232.32Pyrantel hydrochloride
CAS:<p>Pyrantel hydrochloride is the hydrochloride form of Pyrantel. Pyrantel is is an anthelmintic and a nicotinic acetylcholine receptor (nAChR) agonist.</p>Fórmula:C11H15ClN2SPureza:98.01%Cor e Forma:SoildPeso molecular:242.773-Hydroxy desalkylflurazepam
CAS:<p>3-Hydroxy desalkylflurazepam is a benzodiazepine compound with potential sedative and anxiolytic effects.</p>Fórmula:C15H10ClFN2O2Cor e Forma:SolidPeso molecular:304.75-(2-Aminopropyl)indole
CAS:<p>5-(2-Aminopropyl)indole is an orally active psychoactive substance that inhibits monoamine oxidase (MAO) and exhibits long-lasting stimulant effects.</p>Fórmula:C11H14N2Cor e Forma:SolidPeso molecular:174.244-Iodoamphetamine hydrochloride
CAS:<p>4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.</p>Fórmula:C9H13ClINCor e Forma:SolidPeso molecular:297.56SPL-707
CAS:<p>SPL-707 is an effective and selective signal peptide peptidase-like 2a inhibitor (IC50: 80 nM).</p>Fórmula:C27H28FN5O4Pureza:98%Cor e Forma:SolidPeso molecular:505.54Monoamine oxidase
CAS:<p>Enzyme that breaks down amines in the brain and body, affecting mood and brain function.</p>Cor e Forma:Solid(Iso)-Samixogrel
CAS:<p>(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.</p>Fórmula:C25H25ClN2O4SPureza:98.80%Cor e Forma:SolidPeso molecular:484.99[Ala11,D-Leu15]-Orexin B(human)
CAS:<p>OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).</p>Fórmula:C120H206N44O35SPureza:98%Cor e Forma:SolidPeso molecular:2857.28VU6028418
CAS:<p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>Cor e Forma:SolidJF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Cor e Forma:SolidJatrorrhizine hydroxide
CAS:<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Fórmula:C20H21NO5Cor e Forma:SolidPeso molecular:355.38LE 300
CAS:<p>LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.</p>Fórmula:C20H22N2Pureza:97.91% - 98.79%Cor e Forma:SolidPeso molecular:290.4SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Fórmula:C25H30ClN3O3SCor e Forma:SolidPeso molecular:488.04AChE/MAO-B-IN-7
<p>AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.</p>Fórmula:C22H21N3O3Cor e Forma:SolidPeso molecular:375.42α-Casozepine
CAS:<p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>Fórmula:C60H94N14O16Cor e Forma:SolidPeso molecular:1267.47Lupanine hydrochloride
CAS:<p>Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.</p>Fórmula:C15H25ClN2OCor e Forma:SolidPeso molecular:284.83β-Amyloid (1-9)
CAS:<p>This is an N-terminal fragment of beta amyloid.</p>Fórmula:C42H60N14O17Pureza:98%Cor e Forma:SolidPeso molecular:1033.01Encecalinol
CAS:<p>Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].</p>Fórmula:C14H18O3Cor e Forma:SolidPeso molecular:234.29Methyl ganoderate A acetonide
CAS:<p>Methyl ganoderate A from Ganoderma lucidum is a natural AChE inhibitor (IC50=18.35 μM) for Alzheimer's research.</p>Fórmula:C34H50O7Cor e Forma:SolidPeso molecular:570.76SQ-3
<p>SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]</p>Fórmula:C21H21FN2OCor e Forma:SolidPeso molecular:336.4LRRK2 inhibitor 1
CAS:<p>LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.</p>Fórmula:C20H23N5O4Pureza:99.94%Cor e Forma:SolidPeso molecular:397.43N-Methylcyclohexaneethaneamine
CAS:<p>N-Methylcyclohexaneethaneamine is a useful organic compound for research related to life sciences.</p>Fórmula:C9H19NCor e Forma:SolidPeso molecular:141.2539(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Fórmula:C10H10ClNO6Pureza:99.53% - 99.9%Cor e Forma:SoildPeso molecular:275.64SB 258585
CAS:<p>SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.</p>Fórmula:C18H22IN3O3SPureza:99.8%Cor e Forma:SoildPeso molecular:487.364-Butyl-α-agarofuran
CAS:<p>4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.</p>Fórmula:C18H30OCor e Forma:SolidPeso molecular:262.43TAT-CN21
<p>TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.</p>Fórmula:C169H303N69O43Cor e Forma:SolidPeso molecular:3989.65AChE-IN-4
<p>AChE-IN-4 is an acetylcholine esterase inhibitor (AChEI) with an IC50 value of 24.1 μM.</p>Fórmula:C32H25BrN6O4SCor e Forma:SolidPeso molecular:669.55β-Amyloid (1-17)
CAS:<p>This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.</p>Fórmula:C90H130N28O29Pureza:98%Cor e Forma:SolidPeso molecular:2068.2PSEN1-IN-1
<p>PSEN1-IN-1 (Compound (+)-13b) functions as an inhibitor of PSEN1, displaying potent inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with respective IC50</p>Fórmula:C20H19ClF3NO3SCor e Forma:SolidPeso molecular:445.88Furosemide
CAS:<p>Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.</p>Fórmula:C12H11ClN2O5SPureza:99.32% - 99.89%Cor e Forma:Crystals From Aqueous Ethanol Tasteless (Ntp 1992)Peso molecular:330.744Ro60-0175
CAS:<p>Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.</p>Fórmula:C11H12ClFN2Pureza:97.09%Cor e Forma:SolidPeso molecular:226.68DDC 2′,3′-O-disulfate
<p>DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].</p>Fórmula:C17H16O11S2Cor e Forma:SolidPeso molecular:460.43AZD4694 Precursor
CAS:<p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>Fórmula:C22H25N3O7Cor e Forma:SolidPeso molecular:443.45Tampramine
CAS:<p>Tampramine: a TCA and selective norepinephrine inhibitor, with low affinity for other receptors, potential treatment for FST depression.</p>Fórmula:C23H24N4Pureza:99.87%Cor e Forma:SolidPeso molecular:356.46OXA(17-33) TFA
<p>OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).</p>Fórmula:C81H126F3N23O24Cor e Forma:SolidPeso molecular:1863Amyloid β-Protein (3-42)
CAS:<p>Amyloid β-Protein (3-42), the precursor of Pyr peptide, serves as the foundation of the amyloid template block in Alzheimer's disease when modified to</p>Cor e Forma:SolidBuChE-IN-13
<p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>Cor e Forma:Odour SolidmcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Fórmula:C71H99N17O16Cor e Forma:SolidPeso molecular:1446.65(Met(O2)35)-Amyloid β-Protein (1-42)
<p>(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .</p>Fórmula:C203H311N55O62SCor e Forma:SolidPeso molecular:4546.04FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
<p>FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.</p>Fórmula:C227H330N58O66S2Cor e Forma:SolidPeso molecular:4991.53KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Fórmula:C22H12F3N5Na2O7Pureza:97.27%Cor e Forma:SoildPeso molecular:561.33mGluR3 modulator-1
CAS:<p>1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.</p>Fórmula:C16H21N3OPureza:98.99%Cor e Forma:SolidPeso molecular:271.36G923-0271
CAS:<p>G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.</p>Fórmula:C28H23FN4OCor e Forma:SolidPeso molecular:450.51Imipramine N-oxide
CAS:<p>Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.</p>Fórmula:C19H24N2OPureza:99.80%Cor e Forma:SolidPeso molecular:296.41RS 56812
CAS:<p>RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.</p>Fórmula:C18H21N3O2Pureza:99.38%Cor e Forma:SoildPeso molecular:311.38Calcium Channel Compound Library
<p>A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;</p>Cor e Forma:Odour SolidHistamine & Melatonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>Cor e Forma:Odour SolidAmyloid-Forming peptide GNNQQNY
CAS:<p>Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental in</p>Fórmula:C33H48N12O14Cor e Forma:SolidPeso molecular:836.81Donitriptan hydrochloride
CAS:<p>Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively</p>Fórmula:C23H26ClN5O2Pureza:99.8% - 99.86%Cor e Forma:SolidPeso molecular:439.94Salvianolic acid H
CAS:<p>Salvianolic acid H is a strong inhibitor of acetylcholinesterase (AChE) [1].</p>Fórmula:C27H22O12Cor e Forma:SolidPeso molecular:538.46Stacofylline
CAS:<p>Stacofylline is a xanthine derivative that is used to treat migraine headaches.</p>Fórmula:C20H33N7O3Pureza:99.54% - >99.99%Cor e Forma:SolidPeso molecular:419.525β-Cholanic acid
CAS:<p>5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.</p>Fórmula:C24H40O2Pureza:98.91% - 99.89%Cor e Forma:SoildPeso molecular:360.57FFN246
CAS:<p>FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and</p>Fórmula:C15H13FN2OPureza:98%Cor e Forma:SolidPeso molecular:256.2712,14-Dichlorodehydroabietic acid
CAS:<p>12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.</p>Fórmula:C20H26Cl2O2Cor e Forma:SolidPeso molecular:369.33Aducanumab
CAS:<p>Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.</p>Pureza:95% - 97.10%Cor e Forma:LiquidPeso molecular:145.93 kDaZanapezil free base
CAS:<p>Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.</p>Fórmula:C25H32N2OCor e Forma:SolidPeso molecular:376.544Sodium Channel Targeted Library
<p>A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;</p>Cor e Forma:Odour SolidLu AE51090
CAS:<p>Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.</p>Fórmula:C24H29N3O3Pureza:99.57%Cor e Forma:SolidPeso molecular:407.51γ-Secretase Modulators
CAS:<p>gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.</p>Fórmula:C26H24F3N3O3Pureza:98%Cor e Forma:SolidPeso molecular:483.48Emraclidine
CAS:<p>Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.</p>Fórmula:C20H21F3N4OPureza:99.96%Cor e Forma:SolidPeso molecular:390.4SB 216641
CAS:<p>SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.</p>Fórmula:C28H30N4O4Pureza:98.09%Cor e Forma:SolidPeso molecular:486.56LY3027788 hydrochloride
CAS:<p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>Fórmula:C25H32ClF2NO11SCor e Forma:SolidPeso molecular:628.03AChE/BuChE-IN-6
<p>AChE/BuChE-IN-6 (Compound 11f) is an inhibitor of AChE and BuChE, with IC50 values of 1.24 and 1.85 μg/mL, respectively. It exhibits strong DPPH radical scavenging activity (IC50 = 3.15 μg/mL). In vivo toxicity studies demonstrate that AChE/BuChE-IN-6 is safe, showing no significant differences in blood and biochemical parameters compared to controls, and no abnormalities in liver and kidney tissues. This compound shows potential for Alzheimer's disease research.</p>Fórmula:C24H20ClN3O3Cor e Forma:SolidPeso molecular:433.887Mesoridazine Besylate
CAS:<p>Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.</p>Fórmula:C27H32N2O4S3Pureza:99.58%Cor e Forma:SolidPeso molecular:544.75MR33317
<p>MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.</p>Fórmula:C22H28ClN3O2Peso molecular:401.187XL01126
<p>XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.</p>Fórmula:C50H64ClFN10O6S2Cor e Forma:SolidPeso molecular:1019.69Lu AF27139
CAS:<p>Lu AF27139: P2X7 receptor antagonist; IC50: 12 nM (human), 2.4 nM (rat); Ki: 22 (mouse), 54 (human), 13 nM (rat); for CNS research.</p>Fórmula:C21H19ClF3N5O2SPureza:99.96%Cor e Forma:SolidPeso molecular:497.92Amyloid β-Protein (1-24)
CAS:<p>Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.</p>Fórmula:C130H183N35O40Peso molecular:2876.05MGS0028
CAS:<p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>Fórmula:C8H8FNO5Cor e Forma:SolidPeso molecular:217.15Otaplimastat HCl
CAS:<p>Otaplimastat HCl is an MMP inhibitor reducing NMDA-mediated excitotoxicity and oxidative stress, restoring TIMP levels, and protecting vascular permeability.</p>Fórmula:C28H35ClN6O5Pureza:100%Peso molecular:571.07α-Conotoxin imi
CAS:<p>alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.</p>Fórmula:C52H78N20O15S4Pureza:98%Cor e Forma:SolidPeso molecular:1351.56UCM 549
CAS:<p>UCM 549 is a bioactive chemical.</p>Fórmula:C19H21NO2Cor e Forma:SolidPeso molecular:295.38ZZL-7
CAS:<p>ZZL-7 is a rapid antidepressant targeting nNOS & SERT in DRN, crosses blood-brain barrier, with MDD research potential.</p>Fórmula:C11H20N2O4Pureza:99.79%Cor e Forma:SoildPeso molecular:244.29RuBi-Nicotine
CAS:<p>Nicotinic receptor agonist</p>Fórmula:C40H44Cl2N8RuPureza:98%Cor e Forma:SolidPeso molecular:808.81
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