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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5400 produtos de "Neurociência"

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  • SAHM1

    CAS:
    <p>Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.</p>
    Fórmula:C94H162N36O23S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2196.58
  • Dicloromezotiaz

    CAS:
    <p>Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.</p>
    Fórmula:C19H12Cl3N3O2S
    Cor e Forma:Solid
    Peso molecular:452.74
  • Deoxynojirimycin Tetrabenzyl Ether

    CAS:
    <p>Deoxynojirimycin tetrabenzyl ether aids in making 1-dNM, a strong α-glucosidase I &amp; II blocker.</p>
    Fórmula:C34H37NO4
    Cor e Forma:Solid
    Peso molecular:523.673
  • Laniquidar TFA


    <p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>
    Fórmula:C39H37F3N4O5
    Pureza:99.85%
    Cor e Forma:Soild
    Peso molecular:698.73
  • Cyclodrine

    CAS:
    <p>Cyclodrine (Cyclopent) is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.</p>
    Fórmula:C19H29NO3
    Pureza:97.62%
    Cor e Forma:Soild
    Peso molecular:319.44
  • 3-Aminopropylphosphinic acid

    CAS:
    <p>3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).</p>
    Fórmula:C3H10NO2P
    Cor e Forma:Solid
    Peso molecular:123.092
  • 2-Hydroxyalbrassitriol

    CAS:
    <p>2-Hydroxyalbrassitriol (Compound 6) is an AChE inhibitor with an IC 50 of 35.97 μM [1] .</p>
    Fórmula:C15H26O4
    Cor e Forma:Solid
    Peso molecular:270.36
  • COX-2-IN-49


    <p>COX-2-IN-49 (compound 6c) is a potent inhibitor of cyclooxygenase-2 (COX-2), displaying an IC50 value of 2.671 µM. This compound exhibits anti-proliferative properties and holds potential for use in cancer research.</p>
    Cor e Forma:Odour Solid
  • Feralolide

    CAS:
    <p>Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) and</p>
    Fórmula:C18H16O7
    Cor e Forma:Solid
    Peso molecular:344.32
  • AChE-IN-87


    <p>AChE-IN-87 is an AChE inhibitor with an IC50 of 0.05 μM and a Ki of 16.93 nM. It exhibits no cytotoxicity toward 3T3 cells and is suitable for Alzheimer's disease (AD) research.</p>
    Fórmula:C32H39N3O12S2
    Cor e Forma:Solid
    Peso molecular:721.19752
  • LU-32-176B

    CAS:
    <p>LU32-176B is a bioactive chemical.</p>
    Fórmula:C23H24F2N2O2
    Cor e Forma:Solid
    Peso molecular:398.45
  • MK-0969

    CAS:
    <p>MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.</p>
    Fórmula:C24H30F2N4O2
    Cor e Forma:Solid
    Peso molecular:444.52
  • TZ4M


    <p>TZ4M, a 2,4-thiazolidinedione (TZD)-based anti-ADV agent, exhibits neuroprotective effects and acetylcholinesterase (AChE) inhibition in human plasma.</p>
    Fórmula:C19H15NO4S
    Cor e Forma:Solid
    Peso molecular:353.39
  • 2-Methyl-N,N-dimethyltryptamine

    CAS:
    <p>2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.</p>
    Fórmula:C13H18N2
    Cor e Forma:Solid
    Peso molecular:202.3
  • β-Amyloid (1-34)

    CAS:
    <p>This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.</p>
    Fórmula:C170H253N47O52
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3787.2
  • Methyl ganoderate A acetonide

    CAS:
    <p>Methyl ganoderate A from Ganoderma lucidum is a natural AChE inhibitor (IC50=18.35 μM) for Alzheimer's research.</p>
    Fórmula:C34H50O7
    Cor e Forma:Solid
    Peso molecular:570.76
  • Antidepressant agent 4


    <p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>
    Fórmula:C19H38ClN5O2S
    Cor e Forma:Solid
    Peso molecular:436.06
  • Lesogaberan napadisylate

    CAS:
    <p>Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.</p>
    Fórmula:C13H17FNO5PS
    Cor e Forma:Solid
    Peso molecular:349.31
  • Antipsychotic agent-2


    <p>Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.</p>
    Fórmula:C22H26FN5O
    Cor e Forma:Solid
    Peso molecular:395.47
  • Withasomniferolide B

    CAS:
    <p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>
    Fórmula:C28H36O4
    Cor e Forma:Solid
    Peso molecular:436.58
  • (R,R)-Palonosetron Hydrochloride

    CAS:
    <p>(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron</p>
    Fórmula:C19H25ClN2O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:332.87
  • β-Amyloid (4-10)

    CAS:
    <p>Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in</p>
    Fórmula:C39H52N12O12
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:880.9
  • hAChE/hBuChE-IN-1


    <p>hAChE/hBuChE-IN-1 (compound C2) acts as a dual inhibitor of cholinesterases, exhibiting IC50 values of 514 nM for hAChE and 358 nM for hBuChE. It is orally active and capable of enhancing cognitive function and spatial memory.</p>
    Fórmula:C30H31FN2O3
    Cor e Forma:Solid
    Peso molecular:486.577
  • nAChR agonist 2

    CAS:
    <p>Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,</p>
    Fórmula:C11H16N2
    Cor e Forma:Solid
    Peso molecular:176.263
  • Dehydro Aripiprazole (hydrochloride)

    CAS:
    <p>Dehydro aripiprazole, an active atypical antipsychotic metabolite of aripiprazole, is formed by CYP3A4 and CYP2D6.</p>
    Fórmula:C23H26Cl3N3O2
    Cor e Forma:Solid
    Peso molecular:482.83
  • Aloveroside A

    CAS:
    <p>Aloveroside A, a triglucosylnaphthalene derivative extracted from Aloe vera using ethanol, exhibits modest inhibitory activity against bACE, demonstrating</p>
    Fórmula:C30H40O17
    Cor e Forma:Solid
    Peso molecular:672.63
  • SQ-3


    <p>SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]</p>
    Fórmula:C21H21FN2O
    Cor e Forma:Solid
    Peso molecular:336.4
  • Naratriptan D3 Hydrochloride

    CAS:
    <p>Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.</p>
    Fórmula:C17H26ClN3O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:374.94
  • δ-secretase inhibitor 11

    CAS:
    <p>δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.</p>
    Fórmula:C10H12N4O2
    Pureza:99.84%
    Cor e Forma:Solid
    Peso molecular:220.23
  • (±)-Acetylcarnitine chloride

    CAS:
    <p>(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with neuroprotective properties and can be used in studies of neuritis.</p>
    Fórmula:C9H18ClNO4
    Pureza:99.98%
    Cor e Forma:White Crystalline Powder
    Peso molecular:239.7
  • Orexin B, rat, mouse

    CAS:
    <p>Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.</p>
    Fórmula:C126H215N45O34S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2936.45
  • BuChE-IN-13


    <p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>
    Cor e Forma:Odour Solid
  • Dexetimide

    CAS:
    <p>Dexetimide, a muscarinic receptor antagonist, treats neuroleptic-induced parkinsonism.</p>
    Fórmula:C23H26N2O2
    Cor e Forma:Solid
    Peso molecular:362.46
  • Ladostigil hemitartrate

    CAS:
    <p>Ladostigil hemitartrate (TV-3326) inhibits cholinesterase &amp; MAO-B, has neuroprotective traits, and is used in depression &amp; Alzheimer's research.</p>
    Fórmula:C20H26N2O8
    Cor e Forma:Solid
    Peso molecular:422.434
  • VU0364770 hydrochloride

    CAS:
    <p>VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).</p>
    Fórmula:C12H10Cl2N2O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:269.13
  • SL 327

    CAS:
    Fórmula:C16H12F3N3S
    Pureza:>97.0%(HPLC)
    Cor e Forma:White to Light yellow powder to crystal
    Peso molecular:335.35

    Ref: 3B-L0331

    5mg
    65,00€
    25mg
    191,00€
  • Sumatriptan

    CAS:
    <p>Sumatriptan (GR 43175 free base) is a 5-HT1 receptor agonist with anti-inflammatory activity used in acute migraine and acute myocardial infarction.</p>
    Fórmula:C14H21N3O2S
    Pureza:99.93%
    Cor e Forma:White To Off-White Crystalline Powder
    Peso molecular:295.4
  • SSR180711 hydrochloride

    CAS:
    <p>SSR180711 hydrochloride (SSR-180711A HCl) is an Alpha7 nicotinic acetylcholine partial agonist that can be used to study neurolysis.</p>
    Fórmula:C14H18BrClN2O2
    Pureza:99.22%
    Cor e Forma:Solid
    Peso molecular:361.66
  • Mofegiline hydrochloride

    CAS:
    <p>Mofegiline hydrochloride is a potent and selective enzyme-activated irreversible MAO-B inhibitor.</p>
    Fórmula:C11H14ClF2N
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:233.69
  • Altanserin

    CAS:
    <p>Altanserin, a 5-HT2A receptor binder, is tagged with F-18 for brain PET scans.</p>
    Fórmula:C22H22FN3O2S
    Cor e Forma:Solid
    Peso molecular:411.49
  • Isoprocarb

    CAS:
    <p>Isoprocarb is a metabolite of the pesticide.</p>
    Fórmula:C11H15NO2
    Cor e Forma:Solid
    Peso molecular:193.24
  • K 02288

    CAS:
    Fórmula:C20H20N2O4
    Pureza:>98.0%(HPLC)
    Cor e Forma:White to Almost white powder to crystal
    Peso molecular:352.39

    Ref: 3B-K0065

    10mg
    115,00€
    50mg
    363,00€
  • Anti-APP Antibody (8U619)


    <p>Anti-APP Antibody (8U619) is an antibody targeting APP. Anti-APP Antibody (8U619) can be used in ELISA, WB, IF.</p>
    Cor e Forma:Odour Liquid
  • L-655708

    CAS:
    <p>L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM.</p>
    Fórmula:C18H19N3O4
    Pureza:98.41%
    Cor e Forma:Powder
    Peso molecular:341.36
  • Fluvoxamine

    CAS:
    <p>Fluvoxamine (DU-23000) is a selective, orally available 5-HT and serotonin reuptake inhibitor (SSRI) exhibiting antidepressant effects.</p>
    Fórmula:C15H21F3N2O2
    Cor e Forma:Solid
    Peso molecular:318.33
  • Trihexyphenidyl Hydrochloride

    CAS:
    Fórmula:C20H31NO·HCl
    Pureza:>98.0%(T)(HPLC)
    Cor e Forma:White to Almost white powder to crystal
    Peso molecular:337.93

    Ref: 3B-T3303

    5g
    107,00€
    25g
    325,00€
  • Cisatracurium Besylate

    CAS:
    Fórmula:C65H82N2O18S2
    Pureza:>98.0%(HPLC)(qNMR)
    Cor e Forma:White to Light yellow powder to crystal
    Peso molecular:1,243.49

    Ref: 3B-C2940

    1g
    307,00€
    200mg
    93,00€
  • Anti-APP Antibody (3L659)


    <p>Anti-APP Antibody (3L659) is a Mouse antibody targeting APP. Anti-APP Antibody (3L659) can be used in ELISA, WB, IHC, IF.</p>
    Pureza:>95%
    Cor e Forma:Odour Liquid
  • Anti-APP Antibody (5W753)


    <p>Anti-APP Antibody (5W753) is an antibody targeting APP. Anti-APP Antibody (5W753) can be used in ELISA, IF, FCM.</p>
    Cor e Forma:Odour Liquid
  • Saracatinib

    CAS:
    Fórmula:C27H32ClN5O5
    Pureza:>95.0%(HPLC)(qNMR)
    Cor e Forma:White to Light yellow to Light orange powder to crystal
    Peso molecular:542.03

    Ref: 3B-A3611

    25mg
    184,00€