Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(942 produtos)
- ACK(1 produtos)
- AChR(576 produtos)
- ATP Citrato Liase(16 produtos)
- Receptor adrenérgico(2.949 produtos)
- BACE(36 produtos)
- Beta Amilóide(205 produtos)
- CaMK(69 produtos)
- COX(565 produtos)
- Receptor de Dopamina(410 produtos)
- Receptor GABA(337 produtos)
- Gama-secretase(59 produtos)
- GluR(255 produtos)
- GlyT(24 produtos)
- Receptor de Histamina(359 produtos)
- LRRK2(33 produtos)
- Receptor de Melatonina(24 produtos)
- NMDAR(26 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5389 produtos de "Neurociência"
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LP-922761 hydrate
<p>LP-922761 hydrate: selective AAK1 inhibitor; IC50: 4.8 nM (enzyme), 7.6 nM (cellular); also inhibits BIKE (IC50: 24 nM); inert to GAK, opioids, α2, GABAa.</p>Fórmula:C21H28N6O4Cor e Forma:SolidPeso molecular:414.98Eltoprazine
CAS:<p>Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.</p>Fórmula:C12H16N2O2Cor e Forma:SolidPeso molecular:220.27(S)-Amisulpride
CAS:(S)-Amisulpride ((S) Amisulpride) (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist.Fórmula:C17H27N3O4SPureza:98.38%Cor e Forma:SolidPeso molecular:369.48TCN238
CAS:<p>TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).</p>Fórmula:C12H11N3Pureza:99.9% - 99.92%Cor e Forma:SolidPeso molecular:197.24Ziprasidone mesylate
CAS:<p>Ziprasidone mesylate (CP-88059), an oral 5-HT & dopamine blocker, binds D2, 5-HT2A, 5-HT1A with Ki values: 4.8, 0.42, 3.4 nM.</p>Fórmula:C22H25ClN4O4S2Cor e Forma:SolidPeso molecular:509.04Prifinium bromide
CAS:<p>Prifinium bromide is a quaternary ammon antimuscarinic. It inhibits hyperkinesia of the digestive organs and urinary tract and has a spasmolytic action.</p>Fórmula:C22H28BrNPureza:97.99%Cor e Forma:SolidPeso molecular:386.37Acotiamide
CAS:<p>Acotiamide, an oral AChE inhibitor (IC50: 1.79μM), improves gastric motility, targeting functional dyspepsia.</p>Fórmula:C21H30N4O5SCor e Forma:SolidPeso molecular:450.55Risperidone hydrochloride
CAS:<p>Risperidone hydrochloride blocks 5-HT2, inhibits P-glycoprotein, and antagonizes D2 receptors (Ki: 5-HT2A - 4.8 nM, D2 - 5.9 nM).</p>Fórmula:C23H28ClFN4O2Cor e Forma:SolidPeso molecular:446.95Cinanserin
CAS:<p>Cinanserin is a serotonin 5-HT2 antagonist.</p>Fórmula:C20H24N2OSCor e Forma:SolidPeso molecular:340.48S 14506 HCl
CAS:<p>S 14506 HCl: Strong 5-HT1A agonist; pKi - 9.0 (5-HT1A), 6.6 (5-HT1B/C), <6.0 (5-HT3).</p>Fórmula:C24H26FN3O2Cor e Forma:SolidPeso molecular:407.48Syn-Ake acetate
CAS:<p>Syn-Ake acetate (Dipeptide diaminobutyroyl benzylamide) is a muscarinic acetylcholine receptor antagonist.</p>Fórmula:C19H29N5O3·2(C2H4O2)Pureza:99.60%Cor e Forma:SolidPeso molecular:495.58CNQX
CAS:<p>CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)</p>Fórmula:C9H4N4O4Pureza:99.70%Cor e Forma:Pale Yellow SolidPeso molecular:232.15Flibanserin hydrochloride
CAS:<p>Flibanserin HCl: oral 5-HT1A agonist & 5-HT2A antagonist, Ki values 1 nM & 49 nM, for HSDD, has antidepressant/anxiolytic properties.</p>Fórmula:C20H22ClF3N4OCor e Forma:SolidPeso molecular:426.87Edrophonium chloride
CAS:Edrophonium chloride is an acetylcholinesterase (AChE) inhibitor that is known to prevent the breakdown of the neurotransmitter acetylcholine by bindingFórmula:C10H16ClNOPureza:97.41%Cor e Forma:LiquidPeso molecular:201.69Methiothepin mesylate
CAS:<p>Methiothepin mesylate (Metitepine mesylate) is a potent and non-selective 5-HT2 receptor antagonist, used as an antipsychotic.</p>Fórmula:C21H28N2O3S3Pureza:98% - 99.92%Cor e Forma:SolidPeso molecular:452.65SC-560
CAS:<p>SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.</p>Fórmula:C17H12ClF3N2OPureza:99.97%Cor e Forma:SolidPeso molecular:352.74PXS-4728A
CAS:<p>BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive</p>Fórmula:C15H22ClFN2O2Pureza:98.61%Cor e Forma:SolidPeso molecular:316.8WAY-100635 Monomaleate
CAS:<p>WAY-100635 maleate is a selective 5-hydroxytryptamine 1A receptor antagonist with an IC50 value of 0.91 nM and a Ki value of 0.39 nM.</p>Fórmula:C25H34N4O2·C4H4O4Pureza:98.44% - 99.46%Cor e Forma:SolidPeso molecular:538.64HM-30181 mesylate monohydrate
CAS:<p>HM-30181 mesylate monohydrate is an oral P-glycoprotein (P-gp) inhibitor, used to enhance the oral bioavailability of P-gp substrate drugs.</p>Fórmula:C39H42N6O11SPureza:99.37%Cor e Forma:SolidPeso molecular:802.85Sunifiram
CAS:<p>Sunifiram (DM-235) is a potent nootropic agent.</p>Fórmula:C14H18N2O2Pureza:99.57%Cor e Forma:SolidPeso molecular:246.3SAX-187
CAS:<p>SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.</p>Fórmula:C15H13ClN4O2S2Pureza:97.82% - 98%Cor e Forma:SolidPeso molecular:380.87Piperidolate
CAS:<p>Piperidolate inhibits intestinal cramp induced by acetylcholine</p>Fórmula:C21H25NO2Pureza:98.45%Cor e Forma:SolidPeso molecular:323.43Ocinaplon
CAS:<p>Ocinaplon (DOV 273547) is a GABAA receptors modulator.</p>Fórmula:C17H11N5OPureza:99.81%Cor e Forma:SolidPeso molecular:301.3BACE-IN-1 acetate
BACE-IN-1 acetate (350228-37-4), a BACE1 inhibitor with three disulfide bonds and N-linked glycosylation, is used in assays.Fórmula:C75H122N16O29Pureza:96.98%Cor e Forma:SolidPeso molecular:1711.86Metergoline
CAS:Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist.Fórmula:C25H29N3O2Pureza:99.83% - 99.97%Cor e Forma:SolidPeso molecular:403.52Epinastine hydrochloride
CAS:<p>Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis.</p>Fórmula:C16H15N3·HClPureza:99.26% - 99.62%Cor e Forma:White SolidPeso molecular:285.77CTEP
CAS:<p>CTEP (RO 4956371) (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold</p>Fórmula:C19H13ClF3N3OPureza:99.17%Cor e Forma:SolidPeso molecular:391.77SIB-1757
CAS:<p>SIB-1757 (6-methyl-2-[(E)-phenyldiazenyl]pyridin-3) is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)</p>Fórmula:C12H11N3OPureza:97.37%Cor e Forma:SolidPeso molecular:213.24Kavain
CAS:<p>Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of</p>Fórmula:C14H14O3Pureza:99.93% - ≥95%Cor e Forma:SolidPeso molecular:230.26Zaltoprofen
CAS:<p>Zaltoprofen (Soleton) is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.</p>Fórmula:C17H14O3SPureza:99.72%Cor e Forma:Off-White To Pale Yellow Crystalline SolidPeso molecular:298.36Songorine
CAS:<p>Songorine (Napellonine) shows anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.</p>Fórmula:C22H31NO3Pureza:98% - 99.92%Cor e Forma:SolidPeso molecular:357.494i
CAS:<p>4i (CHEMBL1269981) is a 5-HT3 receptor antagonist,It modulates the serotonergic system.</p>Fórmula:C16H12ClN3OPureza:99.49%Cor e Forma:SolidPeso molecular:297.74Geissoschizine methyl ether
CAS:<p>Geissoschizine methyl ether: an alkaloid from Uncaria hook, key in Yokukansan, impacts mood and social behavior enhancing serotonin activity.</p>Fórmula:C22H26N2O3Pureza:99.24% - 99.68%Cor e Forma:SolidPeso molecular:366.45PHCCC
CAS:<p>PHCCC is a Group I mGluR antagonist and enhances mGluR4 function; also blocks mGluR2/8.</p>Fórmula:C17H14N2O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:294.3A-317491
CAS:<p>A-317491 (ABT 202) is a non-nucleotide P2X3 ( Ki: 22 nM) and P2X2/3 receptor (Ki: 9 nM) antagonist, which inhibits calcium flux mediated by the receptors.</p>Fórmula:C33H27NO8Pureza:98.08%Cor e Forma:SolidPeso molecular:565.57IMR-1A
CAS:IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.Fórmula:C13H11NO5S2Pureza:97.1% - 99.76%Cor e Forma:SolidPeso molecular:325.36JNJ16259685
CAS:<p>JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19</p>Fórmula:C20H23NO3Pureza:98.31%Cor e Forma:SolidPeso molecular:325.4Phenylbiguanide
CAS:<p>Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)</p>Fórmula:C8H11N5Pureza:99.54%Cor e Forma:SolidPeso molecular:177.21Farampator
CAS:<p>Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.</p>Fórmula:C12H13N3O2Pureza:99.84% - >99.99%Cor e Forma:SolidPeso molecular:231.25α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Fórmula:C10H16OPureza:97.02% - 98.41%Cor e Forma:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Peso molecular:152.23Tebanicline hydrochloride
CAS:<p>Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.</p>Fórmula:C9H12Cl2N2OPureza:91.74% - 98.71%Cor e Forma:SolidPeso molecular:235.11Temgicoluril
CAS:<p>Temgicoluril (mebikar) acts on GABA Receptor.</p>Fórmula:C8H14N4O2Pureza:99.8%Cor e Forma:SolidPeso molecular:198.22Azeliragon
CAS:Azeliragon (TTP488) is an antagonist at the Receptor for Advanced Glycation End products; is evaluated as a potential treatment for patients with mild-to-Fórmula:C32H38ClN3O2Pureza:96.7% - 98.33%Cor e Forma:SolidPeso molecular:532.12Imidazenil
CAS:<p>Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.</p>Fórmula:C18H12BrFN4OPureza:98.4%Cor e Forma:SolidPeso molecular:399.22Parecoxib
CAS:<p>Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.</p>Fórmula:C19H18N2O4SPureza:99.71% - 99.78%Cor e Forma:SolidPeso molecular:370.42α-Asarone
CAS:<p>alpha-Asarone (trans-Asarone) is a psychoactive compound with antidepressant-like activity in mice.</p>Fórmula:C12H16O3Pureza:99.64% - 99.64%Cor e Forma:Monoclinic Needles From Water Monoclinic Needles From WaterPeso molecular:208.25XAP044
CAS:<p>XAP044 blocks mGlu7, inhibiting long-term potentiation in mouse brain with a half-maximal effect at 88nm.</p>Fórmula:C15H9IO4Pureza:97.41%Cor e Forma:SolidPeso molecular:380.13Zotepine
CAS:<p>Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM,</p>Fórmula:C18H18ClNOSPureza:99.78%Cor e Forma:SolidPeso molecular:331.86Donitriptan Mesylate
CAS:<p>Donitriptan Mesylate, a 5-HT1B/1D agonist, is used potentially for the treatment of migraines.</p>Fórmula:C24H29N5O5SCor e Forma:SolidPeso molecular:499.58Ipsapirone hydrochloride
CAS:<p>Ipsapirone, a pyrimidinylpiperazine ligand, is potent and specific for 5-HT1A receptors and has potential therapeutic use in affective disorders.</p>Fórmula:C19H24ClN5O3SCor e Forma:SolidPeso molecular:437.94
