Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(639 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(2.994 produtos)
- BACE(37 produtos)
- Beta Amilóide(221 produtos)
- CaMK(73 produtos)
- COX(600 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(369 produtos)
- Gama-secretase(57 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(325 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5467 produtos de "Neurociência"
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Piperidolate
CAS:Piperidolate inhibits intestinal cramp induced by acetylcholineFórmula:C21H25NO2Pureza:98.45%Cor e Forma:SolidPeso molecular:323.43U93631
CAS:GABAA antagonist; binds picrotoxin site, stabilizes inactive channel. Speeds GABA-induced Cl- decay, minor peak effect. Inhibits 5-HT3A receptors.Fórmula:C17H21N3O2Pureza:99.65% - 99.76%Cor e Forma:SolidPeso molecular:299.37Donitriptan Mesylate
CAS:Donitriptan Mesylate, a 5-HT1B/1D agonist, is used potentially for the treatment of migraines.Fórmula:C24H29N5O5SCor e Forma:SolidPeso molecular:499.58Fesoterodine
CAS:Fesoterodine is an oral mAChR blocker (pKi: 7.3-8.0) for M1-M5, used to treat OAB.Fórmula:C26H37NO3Pureza:97.1%Cor e Forma:SolidPeso molecular:411.58Ilmetropium iodide
CAS:Ilmetropium iodide is a bronchodilator.Fórmula:C20H30INO3Pureza:98.45%Cor e Forma:SolidPeso molecular:459.36DMAB-anabaseine dihydrochloride
CAS:DMAB-anabaseine dihydrochloride (N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride) is an α7-containingFórmula:C19H23Cl2N3Pureza:99.91%Cor e Forma:SolidPeso molecular:364.31Almotriptan
CAS:Almotriptan (LAS 31416), a triptan and 5-HT1B/1D agonist, treats migraines by constricting cranial vessels and altering blood flow.Fórmula:C17H25N3O2SPureza:99.85%Cor e Forma:Light Yellow Or White PowerPeso molecular:335.46Aripiprazole monohydrate
CAS:Aripiprazole (OPC-14597) is a potent D2 partial agonist and inverse agonist of 5-HT2 receptors, used for schizophrenia and COVID-19 studies.Fórmula:C23H29Cl2N3O3Cor e Forma:SolidPeso molecular:466.4Urapidil
CAS:Urapidil (Ebrantil), a sympatholytic antihypertensive drug, acts as a 5-HT1A receptor agonist and as an α1-adrenoceptor antagonist.Fórmula:C20H29N5O3Pureza:99.85% - >99.99%Cor e Forma:SolidPeso molecular:387.48VU0152100
CAS:VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).Fórmula:C18H19N3O2SPureza:99.56%Cor e Forma:SolidPeso molecular:341.43Ref: TM-T17238
2mg39,00€5mg58,00€10mg92,00€25mg195,00€50mg325,00€100mg522,00€200mg743,00€1mL*10mM (DMSO)64,00€SB 204741
CAS:SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.Fórmula:C14H14N4OSPureza:99.83%Cor e Forma:SolidPeso molecular:286.35Ref: TM-T23312
1mg38,00€2mg50,00€5mg84,00€10mg119,00€25mg234,00€50mg439,00€100mg600,00€200mg837,00€1mL*10mM (DMSO)84,00€VU0467154
CAS:VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.Fórmula:C17H15F3N4O3S2Pureza:99.51% - 99.53%Cor e Forma:SolidPeso molecular:444.45Ref: TM-T17244
1mg47,00€2mg63,00€5mg92,00€10mg126,00€25mg236,00€50mg400,00€100mg695,00€200mg945,00€1mL*10mM (DMSO)101,00€CX516
CAS:CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.Fórmula:C14H15N3OPureza:99.04% - ≥95%Cor e Forma:Tan SolidPeso molecular:241.29S1RA hydrochloride
CAS:S1RA hydrochloride (E-52862 hydrochloride) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, and has good selectivity against σ2R (Ki >Fórmula:C20H24ClN3O2Pureza:98% - 99.84%Cor e Forma:SolidPeso molecular:373.87Ref: TM-T4229
1mg35,00€5mg75,00€10mg105,00€25mg205,00€50mg334,00€100mg492,00€500mg973,00€1mL*10mM (DMSO)84,00€Oxyphenonium bromide
CAS:Oxyphenonium bromide is an anticholinergic used to study and treat ulcers and relieve visceral spasms.
Fórmula:C21H34BrNO3Pureza:98.96%Cor e Forma:SolidPeso molecular:428.404Bestim
CAS:Bestim is an immunomodulatory dipeptide that is synthetic.Fórmula:C16H19N3O5Pureza:99.76%Cor e Forma:SolidPeso molecular:333.34Ref: TM-T25146
1mg88,00€5mg172,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€1mL*10mM (DMSO)182,00€VU0119498
CAS:VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.Fórmula:C15H10BrNO2Pureza:97.56%Cor e Forma:SolidPeso molecular:316.15SAX-187
CAS:SAX-187 (SAX-187) has high-affinity binding at the human 5-HT6 receptor.Fórmula:C15H13ClN4O2S2Pureza:97.82% - 98%Cor e Forma:SolidPeso molecular:380.87Ref: TM-T3183
1mg79,00€5mg152,00€10mg245,00€25mg398,00€50mg532,00€100mg735,00€200mg973,00€1mL*10mM (DMSO)166,00€GNE0877
CAS:GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).Fórmula:C14H16F3N7Pureza:98.01% - 99.97%Cor e Forma:SolidPeso molecular:339.32Ref: TM-T6031
1mg44,00€2mg57,00€5mg113,00€10mg177,00€25mg356,00€50mg532,00€100mg760,00€500mg1.558,00€1mL*10mM (DMSO)90,00€Ondansetron hydrochloride
CAS:Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiationFórmula:C18H19N3O·HClPureza:99.78%Cor e Forma:White PowderPeso molecular:329.82α-Conotoxin PIA acetate
α-Conotoxin PIA acetate is an antagonist of nicotinic acetylcholine receptor (nAChR) mainly targeting α6 and α3 subunits.Pureza:98%Cor e Forma:LiquidPeso molecular:N/AElenbecestat free base
CAS:Elenbecestat (E2609) is a BACE1 inhibitor that reduces Aβ peptide formation, potentially preventing amyloid plaques in the brain.Fórmula:C19H15F6N5O2SCor e Forma:SolidPeso molecular:491.41Olanzapine HCl
CAS:Olanzapine HCl, an FDA-approved atypical antipsychotic for schizophrenia and bipolar disorder, resembles clozapine and quetiapine.Fórmula:C17H21ClN4SCor e Forma:SolidPeso molecular:348.89S26131
CAS:S26131 (N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide) behaves as an antagonist on MT1 and MT2 receptors with Ki ofFórmula:C31H34N2O4Pureza:99.77%Cor e Forma:SolidPeso molecular:498.61Mosapride Citrate
CAS:Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.Fórmula:C21H25ClFN3O3·C6H8O7Pureza:99.70%Cor e Forma:White PowderPeso molecular:614.02Acotiamide monohydrochloride trihydrate
CAS:Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with GI motility-enhancing activity.Fórmula:C21H37ClN4O8SPureza:98% - 99.54%Cor e Forma:SolidPeso molecular:541.06Baclofen hydrochloride
CAS:Baclofen HCL, a GABA-B agonist, treats muscle spasticity by reducing excitatory transmission.Fórmula:C10H13Cl2NO2Pureza:99.55%Cor e Forma:SolidPeso molecular:250.122Glypromate acetate(32302-76-4 free base)
Glypromate acetate is a neuroprotective agent, is a weak NMDA receptor agonist.Fórmula:C14H23N3O8Pureza:99.94%Cor e Forma:SolidPeso molecular:361.35Ref: TM-T7778L
2mg37,00€5mg52,00€10mg74,00€25mg119,00€50mg160,00€100mg225,00€200mg314,00€1mL*10mM (DMSO)57,00€(S)-UFR2709
CAS:(S)-UFR2709, a nAChR competitive antagonist, favors α4β2 over α7, reduces anxiety and alcohol use in rats.Fórmula:C13H17NO2Cor e Forma:SolidPeso molecular:219.284Ansofaxine
CAS:Ansofaxine, an SNRI compound, is commonly utilized in depression research as a serotonin-norepinephrine reuptake inhibitor.Fórmula:C24H31NO3Cor e Forma:SolidPeso molecular:381.516Zotepine
CAS:Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM,Fórmula:C18H18ClNOSPureza:99.78%Cor e Forma:SolidPeso molecular:331.86Trihexyphenidyl hydrochloride
CAS:Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is an antiparkinsonian agent of the antimuscarinic class.Fórmula:C20H32ClNOPureza:99.65%Cor e Forma:SolidPeso molecular:337.927JNJ-40411813
CAS:JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).
Fórmula:C20H25ClN2OPureza:99.74%Cor e Forma:SolidPeso molecular:344.88LP-211
CAS:LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.Fórmula:C30H34N4OPureza:98.65%Cor e Forma:SolidPeso molecular:466.62Ref: TM-T5387
2mg44,00€5mg66,00€10mg90,00€25mg170,00€50mg289,00€100mg462,00€200mg658,00€1mL*10mM (DMSO)73,00€Brexpiprazole
CAS:Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.Fórmula:C25H27N3O2SPureza:99.06% - 99.96%Cor e Forma:SolidPeso molecular:433.57Ref: TM-T2306
5mg50,00€10mg63,00€25mg75,00€50mg88,00€100mg94,00€200mg140,00€500mg259,00€1mL*10mM (DMSO)A consultarAcamprosate calcium
CAS:Acamprosate calcium (Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems, used for treating alcohol dependence.Fórmula:C10H20CaN2O8S2Pureza:98% - 99.93%Cor e Forma:White Odorless Or Nearly Odorless PowderPeso molecular:400.487-Amino-4-(trifluoromethyl)coumarin
CAS:7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a 5-Hydroxytryptamine Receptor Subtype 1E (HTR1E) antagonist.Fórmula:C10H6F3NO2Pureza:97.31% - 97.84%Cor e Forma:Yellow PowderPeso molecular:229.16MDL 72527
CAS:MDL 72527 (N1,N4-Di(buta-2,3-dien-1-yl)butane-1,4-diamine dihydrochloride) is a polyamine oxidase (POA) inhibitorFórmula:C12H22Cl2N2Pureza:98.98%Cor e Forma:SolidPeso molecular:265.22Ref: TM-T22965
1mg38,00€2mg50,00€5mg84,00€10mg119,00€25mg236,00€50mg385,00€100mg575,00€1mL*10mM (DMSO)82,00€Relenopride hydrochloride
CAS:Relenopride, a 5-HT agonist, is used potentially for the treatment of chronic constipation.Fórmula:C24H31Cl2FN4O4Cor e Forma:SolidPeso molecular:529.43Melitracen hydrochloride
CAS:Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.Fórmula:C21H26ClNPureza:99.99%Cor e Forma:Crystalline SolidPeso molecular:327.90Ref: TM-T4274
10mg44,00€25mg64,00€50mg93,00€100mg110,00€200mg161,00€500mg264,00€1mL*10mM (DMSO)48,00€Ethyl (triphenylphosphoranylidene) acetate
CAS:Ethyl (triphenylphosphoranylidene) acetate ((Carbethoxymethylene)triphenylphosphorane) may act as an cholinesterase inhibitor that inhibits AChE and BChE.Fórmula:C22H21O2PPureza:97.985%Cor e Forma:White Or Slight Yellow PowderPeso molecular:348.37Naftopidil dihydrochloride
CAS:Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.Fórmula:C24H28N2O3·2HClPureza:99.76%Cor e Forma:White SolidPeso molecular:465.41Tiagabine hydrochloride hydrate
CAS:Tiagabine HCl hydrate, IC50: 67-446 nM, selectively inhibits GABA uptake, acts as an anticonvulsant.Fórmula:C20H28ClNO3S2Cor e Forma:SolidPeso molecular:430.02Nuciferine
CAS:Nuciferine ((-)-Nuciferine) is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera.Fórmula:C19H21NO2Pureza:98.76% - 99.79%Cor e Forma:SolidPeso molecular:295.38Mivacurium dichloride
CAS:Mivacurium dichloride: non-depolarizing, quick-acting muscle relaxant for minor surgeries and tracheal intubation.Fórmula:C58H80Cl2N2O14Pureza:99.2% - 99.48%Cor e Forma:Off-White SolidPeso molecular:1100.17Ref: TM-T22371
2mg46,00€5mg65,00€10mg94,00€25mg123,00€50mg188,00€100mg286,00€200mg434,00€1mL*10mM (DMSO)90,00€RS-127445 hydrochloride
CAS:RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5).Fórmula:C17H17ClFN3Pureza:99.48%Cor e Forma:SolidPeso molecular:317.79Clothianidin
CAS:Clothianidin (TI 435), an insecticide, stimulates nAChR as acetylcholine agonist, not AChE inhibitor.Fórmula:C6H8ClN5O2SPureza:99.71% - 99.87%Cor e Forma:Solid PowderPeso molecular:249.68CALP1 acetate
CALP1 acetate is a calmodulin (CaM) agonist (Kd of 88 µM) that binds to the CaM EF-hand/Ca2+-binding site.
Fórmula:C42H79N9O12Pureza:99.63%Cor e Forma:SolidPeso molecular:902.13Edrophonium chloride
CAS:Edrophonium chloride is an acetylcholinesterase (AChE) inhibitor that is known to prevent the breakdown of the neurotransmitter acetylcholine by bindingFórmula:C10H16ClNOPureza:97.41%Cor e Forma:LiquidPeso molecular:201.69VU0155041
CAS:VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).Fórmula:C14H15Cl2NO3Pureza:99.52% - 99.56%Cor e Forma:SolidPeso molecular:316.18Ref: TM-T3565
2mg38,00€5mg55,00€10mg80,00€25mg138,00€50mg178,00€100mg285,00€200mg413,00€1mL*10mM (DMSO)60,00€
